Niklas Mattsson

Niklas Mattsson

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Niklas Mattsson

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Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease.

EMBO Mol Med 2019 Nov 11:e11170. Epub 2019 Nov 11.

Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.

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http://dx.doi.org/10.15252/emmm.201911170DOI Listing
November 2019

Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults.

Neurobiol Aging 2019 Oct 22;82:110-119. Epub 2019 Jul 22.

Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA; Department of Psychiatry, University of California, CA, USA; Department of Radiology and Biomedical Imaging, University of California, CA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.07.005DOI Listing
October 2019

Apathy and anxiety are early markers of Alzheimer's disease.

Neurobiol Aging 2019 Oct 19. Epub 2019 Oct 19.

Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden; Memory Clinic, Skåne University Hospital, Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.10.008DOI Listing
October 2019

Primary fatty amides are potential plasma biomarkers for AD.

Nat Rev Neurol 2019 Sep;15(9):498-499

Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1038/s41582-019-0229-6DOI Listing
September 2019

β-amyloid pathology and hippocampal atrophy are independently associated with memory function in cognitively healthy elderly.

Sci Rep 2019 Aug 1;9(1):11180. Epub 2019 Aug 1.

Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund/Malmö, Sweden.

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http://dx.doi.org/10.1038/s41598-019-47638-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671981PMC
August 2019

Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease.

JAMA Neurol 2019 Jul;76(7):791-799

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1001/jamaneurol.2019.0765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583067PMC
July 2019

Determining clinically meaningful decline in preclinical Alzheimer disease.

Neurology 2019 Jul 9;93(4):e322-e333. Epub 2019 Jul 9.

From the Center for Imaging of Neurodegenerative Diseases (M.W., R.S.M.), Department of Veterans Affairs Medical Center; Departments of Radiology and Biomedical Imaging (P.S.I., M.W.) and Psychiatry (P.S.I., R.S.M.), University of California, San Francisco; Clinical Memory Research Unit, Faculty of Medicine (P.S.I., E.S., S.P., O.H., N.M.), Memory Clinic (E.S., S.P., O.H.) and Department of Neurology (N.M.), Skåne University Hospital, and Wallenberg Center for Molecular Medicine (N.M.), Lund University, Sweden; Department of Neurology and Neurological Sciences (E.M.), Stanford University, CA; The Florey Institute (Y.Y.L., C.L.M., P.T.M.), The University of Melbourne; and CogState (P.T.M.), Melbourne, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000007831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669933PMC
July 2019

Staging β-Amyloid Pathology With Amyloid Positron Emission Tomography.

JAMA Neurol 2019 Jul 17. Epub 2019 Jul 17.

Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1001/jamaneurol.2019.2214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646987PMC
July 2019

Biomarkers for tau pathology.

Mol Cell Neurosci 2019 Jun 7;97:18-33. Epub 2018 Dec 7.

Helen Wills Neuroscience Institute, University of California, Berkeley, USA; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.

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http://dx.doi.org/10.1016/j.mcn.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584358PMC
June 2019

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2019.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580449PMC
June 2019

Cerebrospinal fluid neurofilament light is associated with survival in mitochondrial disease patients.

Mitochondrion 2019 05 9;46:228-235. Epub 2018 Jul 9.

Department of Pediatrics, University of Gothenburg, The Queen Silvia's Children Hospital, Gothenburg, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S15677249183002
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http://dx.doi.org/10.1016/j.mito.2018.07.002DOI Listing
May 2019

Predicting diagnosis and cognition with F-AV-1451 tau PET and structural MRI in Alzheimer's disease.

Alzheimers Dement 2019 Apr 25;15(4):570-580. Epub 2019 Jan 25.

Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Malmö, Sweden.

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http://dx.doi.org/10.1016/j.jalz.2018.12.001DOI Listing
April 2019

Accurate risk estimation of β-amyloid positivity to identify prodromal Alzheimer's disease: Cross-validation study of practical algorithms.

Alzheimers Dement 2019 Feb 23;15(2):194-204. Epub 2018 Oct 23.

Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden; Memory Clinic, Skåne University Hospital, Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374284PMC
February 2019

Data-driven approaches for tau-PET imaging biomarkers in Alzheimer's disease.

Hum Brain Mapp 2019 02 19;40(2):638-651. Epub 2018 Oct 19.

Alzheimer Center and Department of Neurology, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, Netherlands.

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http://dx.doi.org/10.1002/hbm.24401DOI Listing
February 2019

Associations between tau, Aβ, and cortical thickness with cognition in Alzheimer disease.

Neurology 2019 02 9;92(6):e601-e612. Epub 2019 Jan 9.

From the Clinical Memory Research Unit (R.O., R.S., O.S., N.M., P.S.I., S.P., O.H.), Lund University, Sweden; Department of Neurology and Alzheimer Center (R.O.), VU University Medical Center, Amsterdam Neuroscience, the Netherlands; Department of Radiation Physics (T.O.), Skåne University Hospital, Lund; Memory Clinic (O.H.), Skåne University Hospital, Malmö, Sweden; and Center for Imaging of Neurodegenerative Diseases (P.S.I.), Department of Veterans Affairs Medical Center, San Francisco, CA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382060PMC
February 2019

Effects of APOE ε4 on neuroimaging, cerebrospinal fluid biomarkers, and cognition in prodromal Alzheimer's disease.

Neurobiol Aging 2018 11 11;71:81-90. Epub 2018 Jul 11.

Department of Clinical Sciences, Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund/Malmö, Sweden; Memory Clinic, Skåne University Hospital, Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.07.003DOI Listing
November 2018

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.

Ann Neurol 2018 11;84(5):729-740

Alzheimer center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/ana.25333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354051PMC
November 2018

The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review.

Alzheimers Dement 2018 10 23;14(10):1313-1333. Epub 2018 Jun 23.

Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.jalz.2018.05.008DOI Listing
October 2018

Chronic depressive symptomatology and CSF amyloid beta and tau levels in mild cognitive impairment.

Int J Geriatr Psychiatry 2018 10 28;33(10):1305-1311. Epub 2018 Jun 28.

Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/gps.4926DOI Listing
October 2018

CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer disease.

Neurology 2018 08 27;91(9):e867-e877. Epub 2018 Jul 27.

From the Clinical Memory Research Unit (S.J., N.M., E.S., O.L., S.P., O.H.), Department of Clinical Sciences, Lund University; Department of Neurology (N.M., S.P.) and Memory Clinic (E.S., O.H.), Skåne University Hospital; Institute of Neuroscience and Physiology (H.Z., K.B.), Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg; Clinical Neurochemistry Laboratory (H.Z., K.B.), Sahlgrenska University Hospital, Sweden; Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology; and UK Dementia Research Institute at UCL (H.Z.), London.

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http://dx.doi.org/10.1212/WNL.0000000000006082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133624PMC
August 2018

Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort study.

Alzheimers Res Ther 2018 08 7;10(1):77. Epub 2018 Aug 7.

Clinical Memory Research Unit, Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1186/s13195-018-0403-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081879PMC
August 2018

Apolipoprotein E genotypes and longevity across dementia disorders.

Alzheimers Dement 2018 07 13;14(7):895-901. Epub 2018 Mar 13.

Department of Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1016/j.jalz.2018.02.003DOI Listing
July 2018

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Authors:
Niklas Mattsson Colin Groot Willemijn J Jansen Susan M Landau Victor L Villemagne Sebastiaan Engelborghs Mark M Mintun Alberto Lleo José Luis Molinuevo William J Jagust Giovanni B Frisoni Adrian Ivanoiu Gaël Chételat Catarina Resende de Oliveira Karen M Rodrigue Johannes Kornhuber Anders Wallin Aleksandra Klimkowicz-Mrowiec Ramesh Kandimalla Julius Popp Pauline P Aalten Dag Aarsland Daniel Alcolea Ina S Almdahl Inês Baldeiras Mark A van Buchem Enrica Cavedo Kewei Chen Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Kiran Dip Gill Olymbia Gkatzima Timo Grimmer Harald Hampel Sanna-Kaisa Herukka Peter Johannsen Koen van Laere Mony J de Leon Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Barbara Mroczko Arto Nordlund Sudesh Prabhakar Oliver Peters Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Frans R J Verhey Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Rik Vandenberghe David J Brooks Tormod Fladby Christopher C Rowe Alexander Drzezga Marcel M Verbeek Marie Sarazin David A Wolk Adam S Fleisher William E Klunk Duk L Na Pascual Sánchez-Juan Dong Young Lee Agneta Nordberg Magda Tsolaki Vincent Camus Juha O Rinne Anne M Fagan Henrik Zetterberg Kaj Blennow Gil D Rabinovici Oskar Hansson Bart N M van Berckel Wiesje M van der Flier Philip Scheltens Pieter Jelle Visser Rik Ossenkoppele

Alzheimers Dement 2018 07 28;14(7):913-924. Epub 2018 Mar 28.

Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.02.009DOI Listing
July 2018

Amyloid pathology in the progression to mild cognitive impairment.

Neurobiol Aging 2018 04 27;64:76-84. Epub 2017 Dec 27.

Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund, Sweden; Department of Neurology, Skåne University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820200PMC
April 2018

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Authors:
Willemijn J Jansen Rik Ossenkoppele Betty M Tijms Anne M Fagan Oskar Hansson William E Klunk Wiesje M van der Flier Victor L Villemagne Giovanni B Frisoni Adam S Fleisher Alberto Lleó Mark A Mintun Anders Wallin Sebastiaan Engelborghs Duk L Na Gäel Chételat José Luis Molinuevo Susan M Landau Niklas Mattsson Johannes Kornhuber Osama Sabri Christopher C Rowe Lucilla Parnetti Julius Popp Tormod Fladby William J Jagust Pauline Aalten Dong Young Lee Rik Vandenberghe Catarina Resende de Oliveira Elisabeth Kapaki Lutz Froelich Adrian Ivanoiu Tomasz Gabryelewicz Marcel M Verbeek Páscual Sanchez-Juan Helmut Hildebrandt Vincent Camus Marzena Zboch David J Brooks Alexander Drzezga Juha O Rinne Andrew Newberg Alexandre de Mendonça Marie Sarazin Gil D Rabinovici Karine Madsen Milica G Kramberger Agneta Nordberg Vincent Mok Barbara Mroczko David A Wolk Philipp T Meyer Magda Tsolaki Philip Scheltens Frans R J Verhey Pieter Jelle Visser Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kaj Blennow Mark A van Buchem Enrica Cavedo Kewei Chen Elena Chipi Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Olymbia Gkatzima Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Peter Johannsen Aleksandra Klimkowicz-Mrowiec Sebastian Köhler Norman Koglin Koen van Laere Mony de Leon Viviana Lisetti Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Arto Nordlund Gerald P Novak George P Paraskevas Gayan Perera Oliver Peters Inez H G B Ramakers Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Henrik Zetterberg

JAMA Psychiatry 2018 01;75(1):84-95

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1001/jamapsychiatry.2017.3391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786156PMC
January 2018

Comparing F-AV-1451 with CSF t-tau and p-tau for diagnosis of Alzheimer disease.

Neurology 2018 01 10;90(5):e388-e395. Epub 2018 Jan 10.

From the Clinical Memory Research Unit (N.M., R.S., O.S., S.P., M.S., P.S.I., O.H.), Faculty of Medicine, Lund University; Memory Clinic (N.M., O.H.) and Departments of Neurology (N.M., R.S., S.P.), Clinical Neurophysiology (D.H.), Radiation Physics (T.O.), and Clinical Physiology and Nuclear Medicine (J.J.), Skåne University Hospital, Lund; MedTech West and the Department of Clinical Neuroscience (M.S.), University of Gothenburg, Sweden; Center for Imaging of Neurodegenerative Diseases (P.S.I.), Department of Veterans Affairs Medical Center, San Francisco; Department of Radiology and Biomedical Imaging (P.S.I.), University of California, San Francisco; Clinical Neurochemistry Laboratory (H.Z., K.B.), Sahlgrenska University Hospital; Institute of Neuroscience and Physiology, Department of Molecular Neuroscience (H.Z., K.B.), the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; and Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791788PMC
January 2018

CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients.

Neurobiol Aging 2017 11 11;59:1-9. Epub 2017 Jul 11.

Department of Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK; UK Dementia Research Institute at UCL, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.06.028DOI Listing
November 2017

Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations.

Alzheimers Res Ther 2017 Oct 23;9(1):87. Epub 2017 Oct 23.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1186/s13195-017-0313-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654097PMC
October 2017

 Cortical Atrophy is Associated with Accelerated Cognitive Decline in Mild Cognitive Impairment with Subsyndromal Depression.

Am J Geriatr Psychiatry 2017 Sep 20;25(9):980-991. Epub 2017 Apr 20.

Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, San Francisco, CA; Departments of Psychiatry, University of California, San Francisco, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2017.04.011DOI Listing
September 2017

Cerebrospinal fluid neurofilament light concentration in motor neuron disease and frontotemporal dementia predicts survival.

Amyotroph Lateral Scler Frontotemporal Degener 2017 08 6;18(5-6):397-403. Epub 2017 Feb 6.

a Institute of Neuroscience and Physiology, Department of Neurochemistry , The Sahlgrenska Academy at the University of Gothenburg , Mölndal , Sweden.

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http://dx.doi.org/10.1080/21678421.2017.1281962DOI Listing
August 2017

Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease.

JAMA Neurol 2017 05;74(5):557-566

Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden5Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Möndal, Sweden.

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http://dx.doi.org/10.1001/jamaneurol.2016.6117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822204PMC
May 2017

Clinical validity of cerebrospinal fluid Aβ42, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework.

Neurobiol Aging 2017 04;52:196-213

Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden; Memory Clinic, Skåne University Hospital, Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.02.034DOI Listing
April 2017

Ex vivo O-labeling mass spectrometry identifies a peripheral amyloid β clearance pathway.

Mol Neurodegener 2017 02 20;12(1):18. Epub 2017 Feb 20.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1186/s13024-017-0152-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317049PMC
February 2017

Cognitive and functional changes associated with Aβ pathology and the progression to mild cognitive impairment.

Neurobiol Aging 2016 12 26;48:172-181. Epub 2016 Aug 26.

Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund University, Lund, Sweden; Department of Neurology, Skåne University Hospital, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.08.017DOI Listing
December 2016

Reply: Do we still need positron emission tomography for early Alzheimer's disease diagnosis?

Brain 2016 11;139(11):e61

Lund University, Department of Clinical Sciences in Malmö, Clinical Memory Research Unit, Sweden.

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http://dx.doi.org/10.1093/brain/aww169DOI Listing
November 2016

Serum neurofilament light protein predicts clinical outcome in traumatic brain injury.

Sci Rep 2016 11 7;6:36791. Epub 2016 Nov 7.

Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Mölndal, SE-43180 Mölndal, Sweden.

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http://dx.doi.org/10.1038/srep36791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098187PMC
November 2016

Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease.

EMBO Mol Med 2016 10 4;8(10):1184-1196. Epub 2016 Oct 4.

Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden Department of Neurology, Skåne University Hospital, Lund, Sweden

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http://dx.doi.org/10.15252/emmm.201606540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048367PMC
October 2016

Plasma tau in Alzheimer disease.

Neurology 2016 Oct 30;87(17):1827-1835. Epub 2016 Sep 30.

From the Clinical Memory Research Unit (N.M., S.J., P.S.I., E.S., S.P., O.H.), Department of Clinical Sciences, Malmö, Lund University; Department of Neurology (N.M., E.S., O.H., S.P.), Skåne University Hospital, Lund; Clinical Neurochemistry Laboratory (H.Z., U.A., K.B.), Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at the University of Gothenburg, Mölndal Canpus, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology, Queen Square, London, UK; Janssen R&D (D.B.), Titusville, NJ; Diagnostics and Life Sciences (C.A.T.H.), GE Global Research, Niskayuna, NY; Quanterix Corporation (A.J., D.H., L.S.), Lexington, MA; Department of Pathology and Laboratory Medicine (L.M.S., J.Q.T.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Center for Imaging of Neurodegenerative Diseases (M.W.W.), Department of Veterans Affairs Medical Center; and Department of Radiology and Biomedical Imaging (M.W.W.), University of California, San Francisco.

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http://dx.doi.org/10.1212/WNL.0000000000003246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089525PMC
October 2016

Selective vulnerability in neurodegeneration: insights from clinical variants of Alzheimer's disease.

J Neurol Neurosurg Psychiatry 2016 09 8;87(9):1000-4. Epub 2016 Jan 8.

Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1136/jnnp-2015-311321DOI Listing
September 2016

Assessing risk for preclinical β-amyloid pathology with , cognitive, and demographic information.

Alzheimers Dement (Amst) 2016 3;4:76-84. Epub 2016 Aug 3.

Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Malmö, Sweden; Department of Neurology, Skåne University Hospital, Lund, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S23528729163003
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http://dx.doi.org/10.1016/j.dadm.2016.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045949PMC
August 2016

Serum visinin-like protein-1 in concussed professional ice hockey players.

Brain Inj 2015 8;29(7-8):872-6. Epub 2015 May 8.

Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital , Mölndal , Sweden .

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http://www.tandfonline.com/doi/full/10.3109/02699052.2015.10
Publisher Site
http://dx.doi.org/10.3109/02699052.2015.1018324DOI Listing
June 2016

Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology.

Neurology 2016 05 15;86(20):1887-96. Epub 2016 Apr 15.

From the Center for Imaging of Neurodegenerative Diseases (P.S.I., R.S.M., R.L.N., D.T., M.W.W.), Department of Veterans Affairs Medical Center, San Francisco; Departments of Radiology and Biomedical Imaging (P.S.I., D.T., M.W.W.) and Psychiatry (R.S.M.), University of California, San Francisco; Clinical Memory Research Unit, Faculty of Medicine (P.S.I., N.M.), Lund University; Memory Clinic (N.M.) and Department of Neurology (N.M.), Skåne University Hospital, Lund University; MedTech West and the Department of Clinical Neuroscience and Rehabilitation (M.S.), University of Gothenburg, Sweden; Department of Neurology (M.C.D., P.S.A.), Keck School of Medicine, University of Southern California, Los Angeles; Helen Wills Neuroscience Institute (W.J.J.), University of California, Berkeley; and Life Sciences Division (M.S., W.J.J.), Lawrence Berkeley National Laboratory, Berkeley CA.

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http://dx.doi.org/10.1212/WNL.0000000000002683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873684PMC
May 2016

Cerebrospinal fluid analysis detects cerebral amyloid-β accumulation earlier than positron emission tomography.

Brain 2016 Apr 2;139(Pt 4):1226-36. Epub 2016 Mar 2.

Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Sweden Memory Clinic, Skåne University Hospital, Sweden

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http://dx.doi.org/10.1093/brain/aww015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806222PMC
April 2016

Increased amyloidogenic APP processing in APOE ɛ4-negative individuals with cerebral β-amyloidosis.

Nat Commun 2016 Mar 7;7:10918. Epub 2016 Mar 7.

Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Simrisbanvägen 14, Malmö 212 24, Sweden.

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http://dx.doi.org/10.1038/ncomms10918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786682PMC
March 2016

CSF Aβ42/Aβ40 and Aβ42/Aβ38 ratios: better diagnostic markers of Alzheimer disease.

Ann Clin Transl Neurol 2016 03 1;3(3):154-65. Epub 2016 Jan 1.

Clinical Memory Research Unit Department of Clinical Sciences, Malmö Lund University Lund Sweden; Memory Clinic Skåne University Hospital Malmö Sweden.

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http://dx.doi.org/10.1002/acn3.274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774260PMC
March 2016

Interaction of Cigarette Smoking History With APOE Genotype and Age on Amyloid Level, Glucose Metabolism, and Neurocognition in Cognitively Normal Elders.

Nicotine Tob Res 2016 Feb 6;18(2):204-11. Epub 2015 Apr 6.

Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, San Francisco, CA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA; Departments of Psychiatry, Medicine, and Neurology, University of California, San Francisco, CA.

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http://dx.doi.org/10.1093/ntr/ntv075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967295PMC
February 2016

Chronic Depressive Symptomatology in Mild Cognitive Impairment Is Associated with Frontal Atrophy Rate which Hastens Conversion to Alzheimer Dementia.

Am J Geriatr Psychiatry 2016 Feb 30;24(2):126-35. Epub 2015 Mar 30.

Center for Imaging of Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, CA; Department of Psychiatry, University of California San Francisco, San Francisco, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2015.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973623PMC
February 2016

Total-tau and neurofilament light in CSF reflect spinal cord ischaemia after endovascular aortic repair.

Neurochem Int 2016 Feb 10;93:1-5. Epub 2015 Dec 10.

Department of Clinical Sciences Malmö, Anaesthesiology and Intensive Care Medicine, Lund University, Skåne University Hospital, Malmö, Sweden.

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http://dx.doi.org/10.1016/j.neuint.2015.12.003DOI Listing
February 2016

Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression.

JAMA Neurol 2016 Jan;73(1):60-7

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1001/jamaneurol.2015.3037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624219PMC
January 2016

Benchmarking biomarker-based criteria for Alzheimer's disease: Data from the Swedish Dementia Registry, SveDem.

Alzheimers Dement 2015 Dec 13;11(12):1470-1479. Epub 2015 Jun 13.

Center for Alzheimer Research, Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences, and Society (NVS), Karolinska Institutet, Stockholm, Sweden; Department of Geriatric Medicine, Karolinska University Hospital, Huddinge, Sweden.

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http://dx.doi.org/10.1016/j.jalz.2015.04.007DOI Listing
December 2015

CSF biomarkers for the differential diagnosis of Alzheimer's disease: A large-scale international multicenter study.

Alzheimers Dement 2015 Nov 21;11(11):1306-15. Epub 2015 Mar 21.

AXA Research Fund & UPMC Chair, Paris, France; Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut de la Mémoire et de la Maladie d'Alzheimer & Institut du Cerveau et de la Moelle épinière (ICM), Département de Neurologie, Hôpital de la Pitié-Salpétrière, Paris, France.

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http://dx.doi.org/10.1016/j.jalz.2014.12.006DOI Listing
November 2015

The transitional association between β-amyloid pathology and regional brain atrophy.

Alzheimers Dement 2015 Oct 9;11(10):1171-9. Epub 2014 Dec 9.

Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2014.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461550PMC
October 2015

Cerebrospinal fluid tau and amyloid-β1-42 in patients with dementia.

Brain 2015 Sep 30;138(Pt 9):2716-31. Epub 2015 Jun 30.

1 Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden 8 UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1093/brain/awv181DOI Listing
September 2015

Cerebrospinal fluid α-synuclein and Lewy body-like symptoms in normal controls, mild cognitive impairment, and Alzheimer's disease.

J Alzheimers Dis 2015 ;43(3):1007-16

Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.3233/JAD-141287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350922PMC
August 2015

Cerebrospinal fluid biomarkers and cerebral atrophy in distinct clinical variants of probable Alzheimer's disease.

Neurobiol Aging 2015 Aug 25;36(8):2340-7. Epub 2015 Apr 25.

Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, CA, USA; Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465267PMC
August 2015

Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2.

Alzheimers Dement 2015 Jul;11(7):740-56

Department of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA; Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA; Department of Radiology, University of California at San Francisco, San Francisco, CA, USA; Department of Medicine, University of California at San Francisco, San Francisco, CA, USA; Department of Neurology, University of California at San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2015.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523217PMC
July 2015

Exploring Alzheimer molecular pathology in Down's syndrome cerebrospinal fluid.

Neurodegener Dis 2014 27;14(2):98-106. Epub 2014 Jun 27.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1159/000358800DOI Listing
May 2015

Predicting Reduction of Cerebrospinal Fluid β-Amyloid 42 in Cognitively Healthy Controls.

JAMA Neurol 2015 May;72(5):554-60

Department of Radiology and Biomedical Imaging, University of California, San Francisco3Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, California.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2014.4530DOI Listing
May 2015

Amyloid biomarkers in Alzheimer's disease.

Trends Pharmacol Sci 2015 May 1;36(5):297-309. Epub 2015 Apr 1.

Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden; UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1016/j.tips.2015.03.002DOI Listing
May 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Authors:
Willemijn J Jansen Rik Ossenkoppele Dirk L Knol Betty M Tijms Philip Scheltens Frans R J Verhey Pieter Jelle Visser Pauline Aalten Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kristen Bibeau Kaj Blennow David J Brooks Mark A van Buchem Vincent Camus Enrica Cavedo Kewei Chen Gael Chetelat Ann D Cohen Alexander Drzezga Sebastiaan Engelborghs Anne M Fagan Tormod Fladby Adam S Fleisher Wiesje M van der Flier Lisa Ford Stefan Förster Juan Fortea Nadia Foskett Kristian S Frederiksen Yvonne Freund-Levi Giovanni B Frisoni Lutz Froelich Tomasz Gabryelewicz Kiran Dip Gill Olymbia Gkatzima Estrella Gómez-Tortosa Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Helmut Hildebrandt Lianna Ishihara Adrian Ivanoiu William J Jagust Peter Johannsen Ramesh Kandimalla Elisabeth Kapaki Aleksandra Klimkowicz-Mrowiec William E Klunk Sebastian Köhler Norman Koglin Johannes Kornhuber Milica G Kramberger Koen Van Laere Susan M Landau Dong Young Lee Mony de Leon Viviana Lisetti Alberto Lleó Karine Madsen Wolfgang Maier Jan Marcusson Niklas Mattsson Alexandre de Mendonça Olga Meulenbroek Philipp T Meyer Mark A Mintun Vincent Mok José Luis Molinuevo Hanne M Møllergård John C Morris Barbara Mroczko Stefan Van der Mussele Duk L Na Andrew Newberg Agneta Nordberg Arto Nordlund Gerald P Novak George P Paraskevas Lucilla Parnetti Gayan Perera Oliver Peters Julius Popp Sudesh Prabhakar Gil D Rabinovici Inez H G B Ramakers Lorena Rami Catarina Resende de Oliveira Juha O Rinne Karen M Rodrigue Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Christopher C Rowe Eckart Rüther Osama Sabri Páscual Sanchez-Juan Isabel Santana Marie Sarazin Johannes Schröder Christin Schütte Sang W Seo Femke Soetewey Hilkka Soininen Luiza Spiru Hanne Struyfs Charlotte E Teunissen Magda Tsolaki Rik Vandenberghe Marcel M Verbeek Victor L Villemagne Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Anders Wallin Åsa K Wallin Jens Wiltfang David A Wolk Marzena Zboch Henrik Zetterberg

JAMA 2015 May;313(19):1924-38

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden87UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jama.2015.4668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486209PMC
May 2015

Biomarkers and cognitive endpoints to optimize trials in Alzheimer's disease.

Ann Clin Transl Neurol 2015 May 21;2(5):534-47. Epub 2015 Mar 21.

Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases San Francisco, California ; Department of Radiology and Biomedical Imaging, University of California San Francisco, California.

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http://dx.doi.org/10.1002/acn3.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435707PMC
May 2015

Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease.

Brain 2015 Mar 24;138(Pt 3):772-83. Epub 2014 Dec 24.

2 Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA 3 Department of Veterans Affairs Medical Centre, Centre for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA.

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http://brain.oxfordjournals.org/content/brain/early/2014/12/
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http://www.brain.oxfordjournals.org/cgi/doi/10.1093/brain/aw
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http://dx.doi.org/10.1093/brain/awu367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339769PMC
March 2015

Brain structure and function as mediators of the effects of amyloid on memory.

Neurology 2015 Mar 13;84(11):1136-44. Epub 2015 Feb 13.

From the Department of Veterans Affairs Medical Center (N.M., P.S.I., S.M., M.W.), Center for Imaging of Neurodegenerative Diseases, San Francisco, CA; Clinical Neurochemistry Laboratory (N.M.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Department of Radiology and Biomedical Imaging (N.M., P.S.I., M.W.), University of California, San Francisco; Alzheimer's Disease Cooperative Study (P.S.A.), Department of Neurosciences, University of California, San Diego, La Jolla; Helen Wills Neuroscience Institute and School of Public Health (W.J.), University of California, Berkeley; and Department of Psychiatry (S.M.), University of California, San Francisco.

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http://www.neurology.org/content/84/11/1136.full.pdf
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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000137
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http://dx.doi.org/10.1212/WNL.0000000000001375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371407PMC
March 2015

Bidirectional links between Alzheimer's disease and Niemann-Pick type C disease.

Neurobiol Dis 2014 Dec 4;72 Pt A:37-47. Epub 2014 Jun 4.

Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Gothenburg, Sweden; UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.05.033DOI Listing
December 2014

The cerebrospinal fluid "Alzheimer profile": easily said, but what does it mean?

Alzheimers Dement 2014 Nov 8;10(6):713-723.e2. Epub 2014 Apr 8.

Alzheimer Center and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S15525260140002
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http://dx.doi.org/10.1016/j.jalz.2013.12.023DOI Listing
November 2014

CSF neurofilament light differs in neurodegenerative diseases and predicts severity and survival.

Neurology 2014 Nov 22;83(21):1945-53. Epub 2014 Oct 22.

From the Clinical Neurochemistry Laboratory (T.S., C.R., N.M., K.B., H.Z.), Institute of Neuroscience and Physiology, Department of Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences, and Society (B.F., D.R., B.W., M.E.), and KI Alzheimer Disease Research Center (A.W.), Karolinska Institutet, Stockholm; Department of Geriatric Medicine (B.F., D.R., M.E.), Karolinska University Hospital, Stockholm, Sweden; Centre for Statistical Methodology (J.W.B.), London School of Hygiene & Tropical Medicine, London, UK; Department of Veterans Affairs Medical Center (N.M.), Center for Imaging of Neurodegenerative Diseases, San Francisco, CA; Clinical Memory Research Unit (K.N.), Department of Clinical Sciences Malmö, Lund University, Malmö; Department of Public Health and Caring Sciences/Geriatrics (L.K.), Uppsala University; Institute of Neuroscience and Physiology (L.R.), Department of Neurology, the Sahlgrenska Academy at the University of Gothenburg, Sweden; and UCL Institute of Neurology (J.M.S., H.Z.), Queen Square, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000001015DOI Listing
November 2014

β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage.

Alzheimers Res Ther 2014 17;6(5-8):75. Epub 2014 Nov 17.

Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, S-431 80 Mölndal, Sweden.

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http://dx.doi.org/10.1186/s13195-014-0075-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233234PMC
November 2014

History of cigarette smoking in cognitively-normal elders is associated with elevated cerebrospinal fluid biomarkers of oxidative stress.

Drug Alcohol Depend 2014 Sep 3;142:262-8. Epub 2014 Jul 3.

Department of Pathology & Laboratory Medicine and Center for Neurodegenerative Diseases Research, Perelman School of Medicine, University of Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2014.06.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144023PMC
September 2014

Effects of baseline CSF α-synuclein on regional brain atrophy rates in healthy elders, mild cognitive impairment and Alzheimer's disease.

PLoS One 2013 31;8(12):e85443. Epub 2013 Dec 31.

Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, United States of America ; Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085443PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877372PMC
August 2014

Diagnostic accuracy of CSF Ab42 and florbetapir PET for Alzheimer's disease.

Ann Clin Transl Neurol 2014 Aug 19;1(8):534-43. Epub 2014 Jul 19.

Department of Radiology and Biomedical Imaging, University of California San Francisco, California ; Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases San Francisco, California.

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http://dx.doi.org/10.1002/acn3.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184556PMC
August 2014

Altered cerebrospinal fluid levels of amyloid β and amyloid precursor-like protein 1 peptides in Down's syndrome.

Neuromolecular Med 2014 Jun 18;16(2):510-6. Epub 2014 Apr 18.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden,

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http://dx.doi.org/10.1007/s12017-014-8302-1DOI Listing
June 2014

Emerging β-amyloid pathology and accelerated cortical atrophy.

JAMA Neurol 2014 Jun;71(6):725-34

Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California3Department of Radiology and Biomedical Imaging, University of California, San Francisco.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2014.446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410966PMC
June 2014

Understanding the cause of sporadic Alzheimer's disease.

Expert Rev Neurother 2014 Jun;14(6):621-30

Department of Psychiatry and Neurochemistry, Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, S-431 80 Mölndal, Sweden.

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http://dx.doi.org/10.1586/14737175.2014.915740DOI Listing
June 2014

Smoking and increased Alzheimer's disease risk: a review of potential mechanisms.

Alzheimers Dement 2014 Jun;10(3 Suppl):S122-45

Center for Imaging of Neurodegenerative Diseases (CIND), San Francisco VA Medical Center, San Francisco, CA, USA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA; Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2014.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098701PMC
June 2014

Association of brain amyloid-β with cerebral perfusion and structure in Alzheimer's disease and mild cognitive impairment.

Brain 2014 May 12;137(Pt 5):1550-61. Epub 2014 Mar 12.

1 Department of Veterans Affairs Medical Centre, Centre for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA.

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http://dx.doi.org/10.1093/brain/awu043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999717PMC
May 2014

Diagnostic performance of cerebrospinal fluid total tau and phosphorylated tau in Creutzfeldt-Jakob disease: results from the Swedish Mortality Registry.

JAMA Neurol 2014 Apr;71(4):476-83

Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden5University College London Institute of Neurology, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2013.6455DOI Listing
April 2014

Assessment of peptide chemical modifications on the development of an accurate and precise multiplex selected reaction monitoring assay for apolipoprotein e isoforms.

J Proteome Res 2014 Feb 14;13(2):1077-87. Epub 2014 Jan 14.

Lunenfeld-Tanenbaum Research Institute, Joseph and Wolf Lebovic Health Complex, Mount Sinai Hospital , 60 Murray Street, Toronto, Ontario, M5T 3L9 Canada.

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http://dx.doi.org/10.1021/pr401060xDOI Listing
February 2014