Publications by authors named "Niklas Lindegardh"

84Publications

Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.

Authors:
Issaka Zongo Fabrice A Somé Serge A M Somda Sunil Parikh Noel Rouamba Philip J Rosenthal Joel Tarning Niklas Lindegardh François Nosten Jean Bosco Ouédraogo

PLoS One 2014 18;9(8):e103200. Epub 2014 Aug 18.

Direction Régionale de l'Ouest, Institut de Recherche en Sciences de la Santé, Bobo-Dioulasso, Burkina Faso; Non Transmissible disease department, Centre Muraz Bobo-Dioulasso, Bobo-Dioulasso, Burkina Faso.

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May 2015

Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso.

Authors:
Innocent Valea Halidou Tinto Maminata Traore-Coulibaly Laeticia C Toe Niklas Lindegardh Joel Tarning Jean-Pierre Van Geertruyden Umberto D'Alessandro Geraint R Davies Stephen A Ward

J Antimicrob Chemother 2014 Sep 2;69(9):2499-507. Epub 2014 Jun 2.

Molecular and Biochemical Parasitolgy, Liverpool School of Tropical Medicine, Liverpool, UK.

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September 2014

Benefits of a pharmacology antimalarial reference standard and proficiency testing program provided by the Worldwide Antimalarial Resistance Network (WWARN).

Authors:
Chris Lourens Niklas Lindegardh Karen I Barnes Philippe J Guerin Carol H Sibley Nicholas J White Joel Tarning

Antimicrob Agents Chemother 2014 Jul 28;58(7):3889-94. Epub 2014 Apr 28.

Worldwide Antimalarial Resistance Network (WWARN) Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

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July 2014

Preliminary pharmaceutical development of antimalarial-antibiotic cotherapy as a pre-referral paediatric treatment of fever in malaria endemic areas.

Authors:
Alexandra Gaubert Tina Kauss Mathieu Marchivie Boubakar B Ba Martine Lembege Fawaz Fawaz Jean-Michel Boiron Xavier Lafarge Niklas Lindegardh Jean-Louis Fabre Nicholas J White Piero L Olliaro Pascal Millet Luc Grislain Karen Gaudin

Int J Pharm 2014 Jul 13;468(1-2):55-63. Epub 2014 Apr 13.

Université de Bordeaux, EA 4575 Analytical and Pharmaceutical Developments Applied to Neglected Diseases and Counterfeits, Bordeaux, France.

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July 2014

Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria.

Authors:
Joel Tarning Niklas Lindegardh Khin Maung Lwin Anna Annerberg Lily Kiricharoen Elizabeth Ashley Nicholas J White François Nosten Nicholas P J Day

Antimicrob Agents Chemother 2014 21;58(4):2052-8. Epub 2014 Jan 21.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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November 2014

Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy.

Authors:
Kimberly K Scarsi Fatai A Fehintola Qing Ma Francesca T Aweeka Kristin M Darin Gene D Morse Ibrahim Temitope Akinola Waheed A Adedeji Niklas Lindegardh Joel Tarning Oladosu Ojengbede Isaac F Adewole Babafemi Taiwo Robert L Murphy Olusegun O Akinyinka Sunil Parikh

J Antimicrob Chemother 2014 May 19;69(5):1370-6. Epub 2014 Jan 19.

Division of Infectious Diseases and Center for Global Health, Northwestern University, Chicago, IL, USA.

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May 2014

Pharmacokinetics of orally administered oseltamivir in healthy obese and nonobese Thai subjects.

Authors:
Podjanee Jittamala Sasithon Pukrittayakamee Joel Tarning Niklas Lindegardh Warunee Hanpithakpong Walter Robert John Taylor Saranath Lawpoolsri Prakaykaew Charunwattana Salwaluk Panapipat Nicholas J White Nicholas P J Day

Antimicrob Agents Chemother 2014 23;58(3):1615-21. Epub 2013 Dec 23.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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October 2014

Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques.

Authors:
Monica Vaccari Claudio Fenizia Zhong-Min Ma Anna Hryniewicz Adriano Boasso Melvin N Doster Christopher J Miller Niklas Lindegardh Joel Tarning Alan L Landay Gene M Shearer Genoveffa Franchini

AIDS Res Hum Retroviruses 2014 Apr 24;30(4):355-62. Epub 2013 Dec 24.

1 Animal Models and Retroviral Vaccines Section, NCI , NIH, Bethesda, Maryland.

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April 2014

Liquid chromatographic-mass spectrometric method for simultaneous determination of small organic acids potentially contributing to acidosis in severe malaria.

Authors:
Natthida Sriboonvorakul Natchanun Leepipatpiboon Arjen M Dondorp Thomas Pouplin Nicholas J White Joel Tarning Niklas Lindegardh

J Chromatogr B Analyt Technol Biomed Life Sci 2013 Dec 16;941:116-22. Epub 2013 Oct 16.

Chromatography and Separation Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.

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December 2013

Reduced susceptibility of Plasmodium falciparum to artesunate in southern Myanmar.

Authors:
Myat P Kyaw Myat H Nyunt Khin Chit Moe M Aye Kyin H Aye Moe M Aye Niklas Lindegardh Joel Tarning Mallika Imwong Christopher G Jacob Charlotte Rasmussen Jamie Perin Pascal Ringwald Myaing M Nyunt

PLoS One 2013 8;8(3):e57689. Epub 2013 Mar 8.

Department of Medical Research (Lower Myanmar), Yangon, The Republic of the Union of Myanmar.

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September 2013

Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers.

Authors:
Insti Instiaty Niklas Lindegardh Podjanee Jittmala Warunee Hanpithakpong Daniel Blessborn Sasithon Pukrittayakamee Nicholas J White Joel Tarning

Antimicrob Agents Chemother 2013 Jun 18;57(6):2858-62. Epub 2013 Mar 18.

Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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June 2013

Pharmacokinetic predictors for recurrent malaria after dihydroartemisinin-piperaquine treatment of uncomplicated malaria in Ugandan infants.

Authors:
Darren J Creek Victor Bigira Shelley McCormack Emmanuel Arinaitwe Humphrey Wanzira Abel Kakuru Jordan W Tappero Taylor G Sandison Niklas Lindegardh Francois Nosten Francesca T Aweeka Sunil Parikh

J Infect Dis 2013 Jun 27;207(11):1646-54. Epub 2013 Feb 27.

Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Australia.

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June 2013

Pharmacokinetic properties of anti-influenza neuraminidase inhibitors.

Authors:
Kalayanee Chairat Joel Tarning Nicholas J White Niklas Lindegardh

J Clin Pharmacol 2013 Feb 24;53(2):119-39. Epub 2013 Jan 24.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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February 2013

Combination therapy with amantadine, oseltamivir and ribavirin for influenza A infection: safety and pharmacokinetics.

Authors:
Sachiko Seo Janet A Englund Jack T Nguyen Sasithon Pukrittayakamee Niklas Lindegardh Joel Tarning Paul A Tambyah Christian Renaud Gregory T Went Menno D de Jong Michael J Boeckh

Antivir Ther 2013 21;18(3):377-86. Epub 2012 Dec 21.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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September 2013

Pharmaceutical development and optimization of azithromycin suppository for paediatric use.

Authors:
Tina Kauss Alexandra Gaubert Chantal Boyer Boubakar B Ba Muriel Manse Stephane Massip Jean-Michel Léger Fawaz Fawaz Martine Lembege Jean-Michel Boiron Xavier Lafarge Niklas Lindegardh Nicholas J White Piero Olliaro Pascal Millet Karen Gaudin

Int J Pharm 2013 Jan 3;441(1-2):218-26. Epub 2012 Dec 3.

Univ. Bordeaux, EA 4575 Analytical and Pharmaceutical Developments Applied to Neglected Diseases and Counterfeits, Bordeaux, France.

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January 2013

A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan.

Authors:
Richard M Hoglund Ishag Adam Warunee Hanpithakpong Michael Ashton Niklas Lindegardh Nicholas P J Day Nicholas J White Francois Nosten Joel Tarning

Malar J 2012 Nov 29;11:398. Epub 2012 Nov 29.

Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, University of Gothenburg, Gothenburg, Sweden.

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November 2012

Population pharmacokinetic and pharmacodynamic properties of intramuscular quinine in Tanzanian children with severe Falciparum malaria.

Authors:
Ilse C E Hendriksen Deogratius Maiga Martha M Lemnge George Mtove Samwel Gesase Hugh Reyburn Niklas Lindegardh Nicholas P J Day Lorenz von Seidlein Arjen M Dondorp Joel Tarning Nicholas J White

Antimicrob Agents Chemother 2013 Feb 26;57(2):775-83. Epub 2012 Nov 26.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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February 2013

Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.

Authors:
Debashish Das Rupam Tripura Aung Pyae Phyo Khin Maung Lwin Joel Tarning Sue J Lee Warunee Hanpithakpong Kasia Stepniewska Didier Menard Pascal Ringwald Kamolrat Silamut Mallika Imwong Kesinee Chotivanich Poravuth Yi Nicholas P J Day Niklas Lindegardh Duong Socheat Chea Nguon Nicholas J White François Nosten Arjen M Dondorp

Clin Infect Dis 2013 Mar 21;56(5):e48-58. Epub 2012 Nov 21.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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March 2013

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study.

Authors:
Chanaki Amaratunga Sokunthea Sreng Seila Suon Erika S Phelps Kasia Stepniewska Pharath Lim Chongjun Zhou Sivanna Mao Jennifer M Anderson Niklas Lindegardh Hongying Jiang Jianping Song Xin-zhuan Su Nicholas J White Arjen M Dondorp Tim J C Anderson Michael P Fay Jianbing Mu Socheat Duong Rick M Fairhurst

Lancet Infect Dis 2012 Nov 30;12(11):851-8. Epub 2012 Aug 30.

Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA.

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November 2012

Population pharmacokinetic and pharmacodynamic modeling of amodiaquine and desethylamodiaquine in women with Plasmodium vivax malaria during and after pregnancy.

Authors:
Joel Tarning Palang Chotsiri Vincent Jullien Marcus J Rijken Martin Bergstrand Mireille Cammas Rose McGready Pratap Singhasivanon Nicholas P J Day Nicholas J White Francois Nosten Niklas Lindegardh

Antimicrob Agents Chemother 2012 Nov 27;56(11):5764-73. Epub 2012 Aug 27.

Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.

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November 2012

Population pharmacokinetics of Artemether and dihydroartemisinin in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda.

Authors:
Joel Tarning Frank Kloprogge Patrice Piola Mehul Dhorda Sulaiman Muwanga Eleanor Turyakira Nitra Nuengchamnong François Nosten Nicholas P J Day Nicholas J White Philippe J Guerin Niklas Lindegardh

Malar J 2012 Aug 22;11:293. Epub 2012 Aug 22.

Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

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August 2012

Pharmacokinetics of piperaquine in pregnant women in Sudan with uncomplicated Plasmodium falciparum malaria.

Authors:
Ishag Adam Joel Tarning Niklas Lindegardh Hyder Mahgoub Rose McGready François Nosten

Am J Trop Med Hyg 2012 Jul;87(1):35-40

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July 2012

Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults.

Authors:
Pauline Byakika-Kibwika Mohammed Lamorde Jonathan Mayito Lillian Nabukeera Rhoda Namakula Harriet Mayanja-Kizza Elly Katabira Muhammad Ntale Nadine Pakker Mairin Ryan Warunee Hanpithakpong Joel Tarning Niklas Lindegardh Peter J de Vries Saye Khoo David Back Concepta Merry

J Antimicrob Chemother 2012 Sep 11;67(9):2213-21. Epub 2012 Jun 11.

Infectious Diseases Institute, Makerere University, Kampala, Uganda.

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September 2012

Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.

Authors:
Anna Färnert Johan Ursing Thomas Tolfvenstam Josea Rono Lillemor Karlsson Elda Sparrelid Niklas Lindegårdh

Malar J 2012 May 25;11:176. Epub 2012 May 25.

Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

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May 2012

Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria.

Authors:
Kris M Jamsen Stephen B Duffull Joel Tarning Niklas Lindegardh Nicholas J White Julie A Simpson

Malar J 2012 Jul 11;11:143. Epub 2012 Jul 11.

Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia.

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July 2012

Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults.

Authors:
Pauline Byakika-Kibwika Mohammed Lamorde Jonathan Mayito Lillian Nabukeera Harriet Mayanja-Kizza Elly Katabira Warunee Hanpithakpong Celestino Obua Nadine Pakker Niklas Lindegardh Joel Tarning Peter J de Vries Concepta Merry

Malar J 2012 Apr 27;11:132. Epub 2012 Apr 27.

Infectious Diseases Institute, Makerere University, PO Box 22418, Kampala, Uganda.

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April 2012

Nevirapine-Based Antiretroviral Therapy Impacts Artesunate and Dihydroartemisinin Disposition in HIV-Infected Nigerian Adults.

Authors:
Fatai A Fehintola Kimberly K Scarsi Qing Ma Sunil Parikh Gene D Morse Babafemi Taiwo Ibrahim Tope Akinola Isaac F Adewole Niklas Lindegardh Aphiradee Phakderaj Oladosu Ojengbede Robert L Murphy Olusegun O Akinyinka Francesca T Aweeka

AIDS Res Treat 2012 5;2012:703604. Epub 2012 Mar 5.

Department of Clinical Pharmacology, University College Hospital and Department of Pharmacology & Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria.

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August 2012

Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults.

Authors:
Pauline Byakika-Kibwika Mohammed Lamorde Violet Okaba-Kayom Harriet Mayanja-Kizza Elly Katabira Warunee Hanpithakpong Nadine Pakker Thomas P C Dorlo Joel Tarning Niklas Lindegardh Peter J de Vries David Back Saye Khoo Concepta Merry

J Antimicrob Chemother 2012 May 8;67(5):1217-23. Epub 2012 Feb 8.

Infectious Diseases Institute, Makerere University, Kampala, Uganda.

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May 2012

Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria.

Authors:
Joel Tarning Marcus J Rijken Rose McGready Aung Pyae Phyo Warunee Hanpithakpong Nicholas P J Day Nicholas J White François Nosten Niklas Lindegardh

Antimicrob Agents Chemother 2012 Apr 17;56(4):1997-2007. Epub 2012 Jan 17.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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April 2012

Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria.

Authors:
Khin Maung Lwin Aung Pyae Phyo Joel Tarning Warunee Hanpithakpong Elizabeth A Ashley Sue J Lee Phaikyeong Cheah Pratap Singhasivanon Nicholas J White Niklas Lindegårdh François Nosten

Antimicrob Agents Chemother 2012 Mar 17;56(3):1571-7. Epub 2012 Jan 17.

Shoklo Malaria Research Unit, Mae Sod, Thailand.

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March 2012

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast.

Authors:
Steffen Borrmann Philip Sasi Leah Mwai Mahfudh Bashraheil Ahmed Abdallah Steven Muriithi Henrike Frühauf Barbara Schaub Johannes Pfeil Judy Peshu Warunee Hanpithakpong Anja Rippert Elizabeth Juma Benjamin Tsofa Moses Mosobo Brett Lowe Faith Osier Greg Fegan Niklas Lindegårdh Alexis Nzila Norbert Peshu Margaret Mackinnon Kevin Marsh

PLoS One 2011 10;6(11):e26005. Epub 2011 Nov 10.

Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya.

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May 2012

Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial.

Authors:
Aung Pyae Phyo Khin Maung Lwin Ric N Price Elizabeth A Ashley Bruce Russell Kanlaya Sriprawat Niklas Lindegardh Pratap Singhasivanon Nicholas J White François Nosten

Clin Infect Dis 2011 Nov;53(10):977-84

Shoklo Malaria Research Unit, Mae Sod.

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November 2011

Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects.

Authors:
Rose McGready Aung Pyae Phyo Marcus J Rijken Joel Tarning Niklas Lindegardh Warunee Hanpithakpon Hla Hla Than Nathar Hlaing Naw Thida Zin Pratap Singhasivanon Nicholas J White François Nosten

Br J Clin Pharmacol 2012 Mar;73(3):467-77

Shoklo Malaria Research Unit, PO Box 46, Mae Sot Tak 63110 Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.

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March 2012

Pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated falciparum malaria.

Authors:
Marcus J Rijken Rose McGready Aung Phae Phyo Niklas Lindegardh Joel Tarning Natthapon Laochan Hla Hla Than Oh Mu Aye Kyi Win Pratap Singhasivanon Nicholas White François Nosten

Antimicrob Agents Chemother 2011 Dec 26;55(12):5500-6. Epub 2011 Sep 26.

Shoklo Malaria Research Unit, PO Box 46 Mae Sot, Tak 63110, Thailand.

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December 2011

Determination of tafenoquine in dried blood spots and plasma using LC and fluorescence detection.

Authors:
Susanne Römsing Niklas Lindegardh Yngve Bergqvist

Bioanalysis 2011 Aug;3(16):1847-53

Dalarna University College, Borlänge, Sweden.

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August 2011

Quantification of dihydroartemisinin, artesunate and artemisinin in human blood: overcoming the technical challenge of protecting the peroxide bridge.

Authors:
Niklas Lindegardh Warunee Hanpithakpong Benjamas Kamanikom Janhom Pattayaso Pratap Singhasivanon Nicholas J White Nicholas P J Day

Bioanalysis 2011 Jul;3(14):1613-24

Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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July 2011

Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria.

Authors:
Kris M Jamsen Stephen B Duffull Joel Tarning Niklas Lindegardh Nicholas J White Julie A Simpson

Malar J 2011 Jul 1;10:181. Epub 2011 Jul 1.

Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia.

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July 2011

Pharmacokinetics of amodiaquine and desethylamodiaquine in pregnant and postpartum women with Plasmodium vivax malaria.

Authors:
Marcus J Rijken Rose McGready Vincent Jullien Joel Tarning Niklas Lindegardh Aung Pyae Phyo Aye Kyi Win Poe Hsi Mireille Cammas Pratap Singhasivanon Nicholas J White François Nosten

Antimicrob Agents Chemother 2011 Sep 27;55(9):4338-42. Epub 2011 Jun 27.

Shoklo Malaria Research Unit, 68/30 Bantung Road, P.O. Box 46, Mae Sot, Tak 63110, Thailand.

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September 2011

A small amount of fat does not affect piperaquine exposure in patients with malaria.

Authors:
Anna Annerberg Khin Maung Lwin Niklas Lindegardh Sakchai Khrutsawadchai Elizabeth Ashley Nicholas P J Day Pratap Singhasivanon Joel Tarning Nicholas J White François Nosten

Antimicrob Agents Chemother 2011 Sep 27;55(9):3971-6. Epub 2011 Jun 27.

Mahidol-Oxford Tropical Medicine Research Unit (MORU), Mahidol University, Bangkok, Thailand.

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September 2011

An open-label crossover study to evaluate potential pharmacokinetic interactions between oral oseltamivir and intravenous zanamivir in healthy Thai adults.

Authors:
Sasithon Pukrittayakamee Podjanee Jittamala Kasia Stepniewska Niklas Lindegardh Sunee Chueasuwanchai Wattana Leowattana Aphiradee Phakdeeraj Sutatip Permpunpanich Warunee Hanpithakpong Wirichada Pan-Ngum Caroline Fukuda Salwaluk Panapipat Pratap Singhasivanon Nicholas J White Nicholas P J Day

Antimicrob Agents Chemother 2011 Sep 20;55(9):4050-7. Epub 2011 Jun 20.

Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Rd., Bangkok 10400, Thailand.

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September 2011

Orally formulated artemisinin in healthy fasting Vietnamese male subjects: a randomized, four-sequence, open-label, pharmacokinetic crossover study.

Authors:
Tran Tinh Hien Warunee Hanpithakpong Nguyen Thanh Truong Nguyen Thi Dung Pham Van Toi Jeremy Farrar Niklas Lindegardh Joel Tarning Michael Ashton

Clin Ther 2011 May;33(5):644-54

Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

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May 2011

Valacyclovir for herpes simplex encephalitis.

Authors:
Thomas Pouplin Julie Nguyen Pouplin Pham Van Toi Niklas Lindegardh H Rogier van Doorn Tran Tinh Hien Jeremy Farrar M Estée Török Tran Thi Hong Chau

Antimicrob Agents Chemother 2011 Jul 16;55(7):3624-6. Epub 2011 May 16.

Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.

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July 2011

Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.

Authors:
Marcus J Rijken Machteld E Boel Bruce Russell Mallika Imwong Mara L Leimanis Aung Pyae Phyo Atis Muehlenbachs Niklas Lindegardh Rose McGready Laurent Rénia Georges Snounou Pratap Singhasivanon François Nosten

Malar J 2011 May 5;10:113. Epub 2011 May 5.

Shoklo Malaria Research Unit, PO Box 46 Mae Sot, Tak 63110, Thailand.

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May 2011

Quantification of the anti-influenza drug zanamivir in plasma using high-throughput HILIC-MS/MS.

Authors:
Niklas Lindegardh Warunee Hanpithakpong Benjamas Kamanikom Jeremy Farrar Tran Tinh Hien Pratap Singhasivanon Nicholas J White Nicholas P J Day

Bioanalysis 2011 Jan;3(2):157-65

Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.

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January 2011

Implementation of a reference standard and proficiency testing programme by the World Wide Antimalarial Resistance Network (WWARN).

Authors:
Chris Lourens William M Watkins Karen I Barnes Carol H Sibley Philippe J Guerin Nicholas J White Niklas Lindegardh

Malar J 2010 Dec 25;9:375. Epub 2010 Dec 25.

Worldwide Antimalarial Resistance Network (WWARN), Oxford, UK.

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December 2010

Intrahost modeling of artemisinin resistance in Plasmodium falciparum.

Authors:
Sompob Saralamba Wirichada Pan-Ngum Richard J Maude Sue J Lee Joel Tarning Niklas Lindegårdh Kesinee Chotivanich François Nosten Nicholas P J Day Duong Socheat Nicholas J White Arjen M Dondorp Lisa J White

Proc Natl Acad Sci U S A 2011 Jan 20;108(1):397-402. Epub 2010 Dec 20.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Rajthevee, Bangkok 10400, Thailand.

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January 2011

Assay for screening for six antimalarial drugs and one metabolite using dried blood spot sampling, sequential extraction and ion-trap detection.

Authors:
Daniel Blessborn Susanne Romsing Yngve Bergqvist Niklas Lindegardh

Bioanalysis 2010 Nov;2(11):1839-47

Dalarna University College, Borlange, Sweden.

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November 2010

Efficacy and safety of artemether-lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: an open-label, randomised, non-inferiority trial.

Authors:
Patrice Piola Carolyn Nabasumba Eleanor Turyakira Mehul Dhorda Niklas Lindegardh Dan Nyehangane Georges Snounou Elizabeth A Ashley Rose McGready Francois Nosten Philippe J Guerin

Lancet Infect Dis 2010 Nov;10(11):762-9

Epicentre, Paris, France.

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November 2010

Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine.

Authors:
Shabana Ali Muzammil H Najmi Joel Tarning Niklas Lindegardh

Malar J 2010 Oct 11;9:275. Epub 2010 Oct 11.

Department of Pharmacology and Therapeutics, Army Medical College, National University of Sciences and Technology (NUST), Islamabad, Pakistan.

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October 2010

Population pharmacokinetics and pharmacodynamics of artemether and lumefantrine during combination treatment in children with uncomplicated falciparum malaria in Tanzania.

Authors:
Sofia Friberg Hietala Andreas Mårtensson Billy Ngasala Sabina Dahlström Niklas Lindegårdh Anna Annerberg Zul Premji Anna Färnert Pedro Gil Anders Björkman Michael Ashton

Antimicrob Agents Chemother 2010 Nov 16;54(11):4780-8. Epub 2010 Aug 16.

Department of Pharmacology, University of Gothenburg, Gothenburg, Sweden.

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November 2010

Laboratory capacity building in Asia for infectious disease research: experiences from the South East Asia Infectious Disease Clinical Research Network (SEAICRN).

Authors:
Heiman F L Wertheim Pilaipan Puthavathana Ngoc My Nghiem H Rogier van Doorn Trung Vu Nguyen Hung Viet Pham Decy Subekti Syahrial Harun Suhud Malik Janet Robinson Motiur Rahman Walter Taylor Niklas Lindegardh Steve Wignall Jeremy J Farrar Menno D de Jong

PLoS Med 2010 Apr 6;7(4):e1000231. Epub 2010 Apr 6.

South East Asia Infectious Diseases Clinical Research Network, National Hospital of Tropical Diseases, Hanoi, Vietnam.

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April 2010

Comparison of plasma, venous and capillary blood levels of piperaquine in patients with uncomplicated falciparum malaria.

Authors:
Elizabeth A Ashley Kasia Stepniewska Niklas Lindegardh Anna Annerberg Joel Tarning Rose McGready Lucy Phaiphun Pratap Singhasivanon Nicholas J White François Nosten

Eur J Clin Pharmacol 2010 Jul 19;66(7):705-12. Epub 2010 Mar 19.

Shoklo Malaria Research Unit, Mae Sot, Thailand.

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July 2010

Possible neuropsychiatric reaction to high-dose oseltamivir during acute 2009 H1N1 influenza A infection.

Authors:
Kenta Nakamura Brian S Schwartz Niklas Lindegårdh Chris Keh B Joseph Guglielmo

Clin Infect Dis 2010 Apr;50(7):e47-9

School of Medicine, University of California, San Francisco, California, USA.

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April 2010

Acute encephalopathy associated with influenza A infection in adults.

Authors:
Nelson Lee Chun Kwok Wong Paul K S Chan Niklas Lindegardh Nicholas J White Frederick G Hayden Edward H C Wong Ka Shing Wong Clive S Cockram Joseph J Y Sung David S C Hui

Emerg Infect Dis 2010 Jan;16(1):139-42

Division of Infectious Diseases, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, 9/F Clinical Sciences Building, Department of Medicine and Therapeutics, Shatin, Hong Kong, People's Republic of China.

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January 2010

Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda.

Authors:
Julia Mwesigwa Sunil Parikh Bryan McGee Polina German Troy Drysdale Joan N Kalyango Tamara D Clark Grant Dorsey Niklas Lindegardh Anna Annerberg Philip J Rosenthal Moses R Kamya Francesca Aweeka

Antimicrob Agents Chemother 2010 Jan 19;54(1):52-9. Epub 2009 Oct 19.

Department of Medicine, 1001 Potrero Avenue, Building 30, Room 3402, University of California, San Francisco, San Francisco, CA 94143-0811, USA.

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January 2010

Towards optimal design of anti-malarial pharmacokinetic studies.

Authors:
Julie A Simpson Kris M Jamsen Ric N Price Nicholas J White Niklas Lindegardh Joel Tarning Stephen B Duffull

Malar J 2009 Aug 6;8:189. Epub 2009 Aug 6.

Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Melbourne, Victoria, Australia.

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August 2009

Artemisinin resistance in Plasmodium falciparum malaria.

Authors:
Arjen M Dondorp François Nosten Poravuth Yi Debashish Das Aung Phae Phyo Joel Tarning Khin Maung Lwin Frederic Ariey Warunee Hanpithakpong Sue J Lee Pascal Ringwald Kamolrat Silamut Mallika Imwong Kesinee Chotivanich Pharath Lim Trent Herdman Sen Sam An Shunmay Yeung Pratap Singhasivanon Nicholas P J Day Niklas Lindegardh Duong Socheat Nicholas J White

N Engl J Med 2009 Jul;361(5):455-67

Mahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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July 2009

Population pharmacokinetics of lumefantrine in pregnant women treated with artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria.

Authors:
Joel Tarning Rose McGready Niklas Lindegardh Elizabeth A Ashley Mupawjay Pimanpanarak Benjamas Kamanikom Anna Annerberg Nicholas P J Day Kasia Stepniewska Pratap Singhasivanon Nicholas J White François Nosten

Antimicrob Agents Chemother 2009 Sep 29;53(9):3837-46. Epub 2009 Jun 29.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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September 2009

Lopinavir/ritonavir affects pharmacokinetic exposure of artemether/lumefantrine in HIV-uninfected healthy volunteers.

Authors:
Polina German Sunil Parikh Jody Lawrence Grant Dorsey Philip J Rosenthal Diane Havlir Edwin Charlebois Warunee Hanpithakpong Niklas Lindegardh Francesca T Aweeka

J Acquir Immune Defic Syndr 2009 Aug;51(4):424-9

Department of Clinical Pharmacy, Drug Research, University of California, School of Medicine, San Francisco, CA 94143-0622, USA.

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August 2009

A liquid chromatographic-tandem mass spectrometric method for determination of artemether and its metabolite dihydroartemisinin in human plasma.

Authors:
Warunee Hanpithakpong Benjamas Kamanikom Pratap Singhasivanon Nicholas J White Nicholas Pj Day Niklas Lindegardh

Bioanalysis 2009 Apr;1(1):37-46

Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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April 2009

Guidelines for field surveys of the quality of medicines: a proposal.

Authors:
Paul N Newton Sue J Lee Catherine Goodman Facundo M Fernández Shunmay Yeung Souly Phanouvong Harparkash Kaur Abdinasir A Amin Christopher J M Whitty Gilbert O Kokwaro Niklas Lindegårdh Patrick Lukulay Lisa J White Nicholas P J Day Michael D Green Nicholas J White

PLoS Med 2009 Mar;6(3):e52

Wellcome Trust-Mahosot Hospital-Oxford University Tropical Medicine Research Collaboration, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.

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March 2009

A randomised controlled trial of artemether-lumefantrine versus artesunate for uncomplicated plasmodium falciparum treatment in pregnancy.

Authors:
Rose McGready Saw Oo Tan Elizabeth A Ashley Mupawjay Pimanpanarak Jacher Viladpai-Nguen Lucy Phaiphun Katja Wüstefeld Marion Barends Natthapon Laochan Lily Keereecharoen Niklas Lindegardh Pratap Singhasivanon Nicholas J White François Nosten

PLoS Med 2008 Dec;5(12):e253

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December 2008

Does artesunate prolong the electrocardiograph QT interval in patients with severe malaria?

Authors:
Richard J Maude Katherine Plewes M Abul Faiz Josh Hanson Prakaykaew Charunwatthana Sue J Lee Joel Tärning Emran Bin Yunus M Gofranul Hoque Mahatab Uddin Hasan Amir Hossain Niklas Lindegardh Nicholas P J Day Nicholas J White Arjen M Dondorp

Am J Trop Med Hyg 2009 Jan;80(1):126-32

Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.

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January 2009

Oseltamivir is adequately absorbed following nasogastric administration to adult patients with severe H5N1 influenza.

Authors:
Walter R J Taylor Bui Nghia Thinh Giang Thuc Anh Peter Horby Heiman Wertheim Niklas Lindegardh Menno D de Jong Kasia Stepniewska Tran Thuy Hanh Nguyen Duc Hien Ngo Minh Bien Ngo Quy Chau Annette Fox Nghiem My Ngoc Martin Crusat Jeremy J Farrar Nicholas J White Nguyen Hong Ha Trinh Thi Lien Nguyen Vu Trung Nicholas Day Nguyen Gia Binh

PLoS One 2008 15;3(10):e3410. Epub 2008 Oct 15.

Oxford University Clinical Research Unit, Hanoi, Vietnam.

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December 2008

Adherence and efficacy of supervised versus non-supervised treatment with artemether/lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Bangladesh: a randomised controlled trial.

Authors:
Md Mushfiqur Rahman Arjen M Dondorp Nicholas P J Day Niklas Lindegardh Mallika Imwong M A Faiz A Mannan Bangali A T M Mustafa Kamal Jahirul Karim Jaranit Kaewkungwal Pratap Singhasivanon

Trans R Soc Trop Med Hyg 2008 Sep 7;102(9):861-7. Epub 2008 Jul 7.

Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.

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September 2008

Quantification of the antimalarial piperaquine in plasma.

Authors:
Joel Tarning Niklas Lindegardh

Trans R Soc Trop Med Hyg 2008 May;102(5):409-11

Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand.

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May 2008

Plasmodium vivax resistance to chloroquine in Dawei, southern Myanmar.

Authors:
Jean-Paul Guthmann Anne Pittet Alexandre Lesage Mallika Imwong Niklas Lindegardh Myo Min Lwin Than Zaw Anna Annerberg Xavier de Radiguès François Nosten

Trop Med Int Health 2008 Jan;13(1):91-8

Epicentre, Paris, France.

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January 2008

World Antimalarial Resistance Network (WARN) IV: clinical pharmacology.

Authors:
Karen I Barnes Niklas Lindegardh Olumide Ogundahunsi Piero Olliaro Christopher V Plowe Milijaona Randrianarivelojosia Grace O Gbotosho William M Watkins Carol H Sibley Nicholas J White

Malar J 2007 Sep 6;6:122. Epub 2007 Sep 6.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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September 2007

Importance of collection tube during clinical studies of oseltamivir.

Authors:
Niklas Lindegardh Geraint R Davies Tran Tinh Hien Jeremy Farrar Pratap Singhasivanon Nicholas P J Day Nicholas J White

Antimicrob Agents Chemother 2007 May 26;51(5):1835-6. Epub 2007 Feb 26.

Wellcome Trust-Mahidol University-Oxford Tropical Medicine Research Programme, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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May 2007

Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz.

Authors:
Polina German Bryan Greenhouse Carrie Coates Grant Dorsey Philip J Rosenthal Edwin Charlebois Niklas Lindegardh Diane Havlir Francesca T Aweeka

Clin Infect Dis 2007 Mar;44(6):889-91

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March 2007

Pharmacokinetic study of artemether-lumefantrine given once daily for the treatment of uncomplicated multidrug-resistant falciparum malaria.

Authors:
Elizabeth A Ashley Kasia Stepniewska Niklas Lindegårdh Rose McGready Anna Annerberg Robert Hutagalung Thida Singtoroj Gilvary Hla Al Brockman Stephane Proux Jahser Wilahphaingern Pratap Singhasivanon Nicholas J White François Nosten

Trop Med Int Health 2007 Feb;12(2):201-8

Shoklo Malaria Research Unit, Mae Sot, Thailand.

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February 2007

How much fat is necessary to optimize lumefantrine oral bioavailability?

Authors:
Elizabeth A Ashley Kasia Stepniewska Niklas Lindegårdh Anna Annerberg Am Kham Al Brockman Pratap Singhasivanon Nicholas J White François Nosten

Trop Med Int Health 2007 Feb;12(2):195-200

Shoklo Malaria Research Unit, Mae Sot, Thailand.

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February 2007

Efficacy of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia.

Authors:
Mey Bouth Denis Reiko Tsuyuoka Pharath Lim Niklas Lindegardh Poravuth Yi Sophoan Narann Top Duong Socheat Thierry Fandeur Anna Annerberg Eva Maria Christophel Pascal Ringwald

Trop Med Int Health 2006 Dec;11(12):1800-7

National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.

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December 2006

The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria.

Authors:
Rose McGready Kasia Stepniewska Niklas Lindegardh Elizabeth A Ashley Yar La Pratap Singhasivanon Nicholas J White François Nosten

Eur J Clin Pharmacol 2006 Dec 20;62(12):1021-31. Epub 2006 Oct 20.

Shoklo Malaria Research Unit, P.O. Box 46, Mae Sot, Tak, Thailand.

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December 2006

Pharmacokinetic and pharmacodynamic assessment of co-amoxiclav in the treatment of melioidosis.

Authors:
Wirongrong Chierakul Jinda Wangboonskul Thida Singtoroj Wirichada Pongtavornpinyo Jennifer M Short Bina Maharjan Vanaporn Wuthiekanun David A B Dance Prapit Teparrukkul Niklas Lindegardh Sharon J Peacock Nicholas P Day Wipada Chaowagul Nicholas J White

J Antimicrob Chemother 2006 Dec 26;58(6):1215-20. Epub 2006 Sep 26.

Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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December 2006

Rapid degradation of oseltamivir phosphate in clinical samples by plasma esterases.

Authors:
Niklas Lindegardh Geraint R Davies Tinh Hien Tran Jeremy Farrar Pratap Singhasivanon Nicholas P J Day Nicholas J White

Antimicrob Agents Chemother 2006 Sep;50(9):3197-9

Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand.

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September 2006

Population pharmacokinetic assessment of a new regimen of mefloquine used in combination treatment of uncomplicated falciparum malaria.

Authors:
Elizabeth A Ashley Kasia Stepniewska Niklas Lindegårdh Rose McGready Robert Hutagalung Rae Hae Pratap Singhasivanon Nicholas J White François Nosten

Antimicrob Agents Chemother 2006 Jul;50(7):2281-5

Shoklo Malaria Research Unit, P.O. Box 46, Mae Sot, Tak 63110, Thailand.

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July 2006

Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.

Authors:
Frank Smithuis Moe Kyaw Kyaw Ohn Phe Khin Zarli Aye Linn Htet Marion Barends Niklas Lindegardh Thida Singtoroj Elizabeth Ashley Saw Lwin Kasia Stepniewska Nicholas J White

Lancet 2006 06;367(9528):2075-85

Médecins Sans Frontières (Holland), Yangon, Myanmar.

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June 2006

Pitfalls in estimating piperaquine elimination.

Authors:
Joel Tarning Niklas Lindegårdh Anna Annerberg Thida Singtoroj Nicholas P J Day Michael Ashton Nicholas J White

Antimicrob Agents Chemother 2005 Dec;49(12):5127-8

Department of Pharmacology, Göteborg University, Sweden.

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December 2005

Therapeutic efficacy of artemether-lumefantrine and artesunate-mefloquine for treatment of uncomplicated Plasmodium falciparum malaria in Luang Namtha Province, Lao People's Democratic Republic.

Authors:
Jörg M Stohrer Sabine Dittrich Vonthalom Thongpaseuth Viengxay Vanisaveth Rattanaxay Phetsouvanh Samlane Phompida Feliciano Monti Eva-Maria Christophel Niklas Lindegardh Anna Annerberg Tomas Jelinek

Trop Med Int Health 2004 Nov;9(11):1175-83

Institute of Tropical Medicine, Charité, Berlin, Germany.

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November 2004

Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.

Authors:
Mayfong Mayxay Maniphone Khanthavong Niklas Lindegårdh Siamphay Keola Marion Barends Tiengkham Pongvongsa Ratsuda Yapom Anna Annerberg Samlane Phompida Rattanaxay Phetsouvanh Nicholas J White Paul N Newton

Clin Infect Dis 2004 Oct 27;39(8):1139-47. Epub 2004 Sep 27.

Wellcome Trust-Mahosot Hospital, Oxford Tropical Medicine Research Collaboration, Vientiane, Lao PDR.

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October 2004

Determination of pyronaridine in whole blood by automated solid phase extraction and high-performance liquid chromatography.

Authors:
Daniel Blessborn Niklas Lindegårdh Orjan Ericsson Urban Hellgren Yngve Bergqvist

Ther Drug Monit 2003 Jun;25(3):264-70

Dalarna University College, Borlänge, Sweden.

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June 2003

Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports.

Authors:
Anna Färnert Johan Lindberg Pedro Gil Göte Swedberg Yngve Berqvist Mita M Thapar Niklas Lindegårdh Sándor Berezcky A Björkman

BMJ 2003 Mar;326(7390):628-9

Department of Medicine, Division of Infectious Diseases, Karolinska Institute, Karolinska Hospital, S-171 76 Stockholm, Sweden.

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March 2003

Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis.

Authors:
Mita M Thapar Michael Ashton Niklas Lindegårdh Yngve Bergqvist Sabina Nivelius Inger Johansson Anders Björkman

Eur J Clin Pharmacol 2002 Apr 28;58(1):19-27. Epub 2002 Feb 28.

Department of Infectious Diseases, Malaria Research Laboratory, L7/03, Karolinska Hospital, Stockholm 17176, Sweden.

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April 2002