Publications by authors named "Nikki Duong"

9 Publications

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The impact of the gut microbiome on liver transplantation.

Curr Opin Organ Transplant 2021 Oct 11. Epub 2021 Oct 11.

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia, USA.

Purpose Of Review: Although gut dysbiosis can hasten disease progression in end-stage liver disease and contribute to disease severity, morbidity and mortality, its impact during and after transplant needs further study.

Recent Findings: Changes in the microbiome are associated with hepatic decompensation. Immune homeostasis is further disrupted during transplant and with immunosuppressants required after transplant. There is increasing evidence of the role of microbiota in peri and posttransplant complications.

Summary: Although transplant is highly successful with acceptable survival rates, infections, rejection, disease recurrence and death remain important complications. Prognostication and interventions involving the gut microbiome could be beneficial.
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http://dx.doi.org/10.1097/MOT.0000000000000930DOI Listing
October 2021

Effects of a Resident-Led Subject Exam Review on Mean Scores of Internal Medicine Subject Exam: a Case-control Study.

Med Sci Educ 2021 Feb 24;31(1):49-52. Epub 2020 Nov 24.

Department of Medicine, MedStar Georgetown University Hospital, 3800 Reservoir Rd, NW, Washington, DC 20007 USA.

The National Board of Medical Examiners (NBME) offers Subject Examinations (SE) for students completing the Internal Medicine (IM) clerkship. There is a paucity of literature in regard to the efficacy of review methods prior to rendering said examination. Our medical center's residents conducted a structured review session in preparation for SE administration. The mean SE scores prior to and after the initiation of the resident-led review session were compared. There was no statistically significant association found between the mean NBME scores in the experimental or control groups. We propose that alternative methods be further assessed for efficacy.
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http://dx.doi.org/10.1007/s40670-020-01157-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368476PMC
February 2021

Reply.

Clin Gastroenterol Hepatol 2021 Jun 29. Epub 2021 Jun 29.

Virginia Commonwealth University and Central Virginia Veterans Healthcare System, Richmond, Virginia.

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http://dx.doi.org/10.1016/j.cgh.2021.06.031DOI Listing
June 2021

Bowel Movement Frequency Is Not Linked With Cognitive Function in Cirrhosis.

Clin Gastroenterol Hepatol 2021 May 13. Epub 2021 May 13.

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and Central Virginia Veterans Healthcare System, Richmond, Virginia. Electronic address:

The spectrum of hepatic encephalopathy (HE) ranges from overt HE (OHE) to cognitive impairment (ie, covert) HE (CHE). The first-line therapy is lactulose, which is titrated to achieve ~2-3 soft/loose daily bowel movements (BM). This metric is considered dogma for practitioners despite erratic results, GI adverse events, and poor tolerance in Western countries. There are logistic barriers for the widespread uptake of rifaximin, the second-line therapy. Moreover, although BM frequency-directed dose titration of lactulose is the usual practice, its impact on objective cognitive performance is unclear. Our aim is to determine the impact of BM frequency on cognition in patients with/without prior OHE.
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http://dx.doi.org/10.1016/j.cgh.2021.05.014DOI Listing
May 2021

The Impact of Frailty, Sarcopenia, and Malnutrition on Liver Transplant Outcomes.

Clin Liver Dis (Hoboken) 2021 Apr 1;17(4):271-276. Epub 2021 May 1.

MedStar Georgetown Transplant Institute Georgetown University Hospital Washington DC.

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http://dx.doi.org/10.1002/cld.1043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087926PMC
April 2021

Author Spotlight: Nikki Duong.

Authors:
Nikki Duong

Dig Dis Sci 2020 08;65(8):2176

Department of Internal Medicine, Georgetown University Hospital, Washington, DC, USA.

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http://dx.doi.org/10.1007/s10620-020-06294-3DOI Listing
August 2020

How to Become a Competitive Applicant for Gastroenterology Fellowship: Tips and Tricks for Success Part II.

Dig Dis Sci 2020 08;65(8):2172-2175

Division of Gastroenterology, Hepatology and Nutrition, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, USA.

In recent years, gastroenterology has become one of the most competitive subspecialties included in the internal medicine fellowship match, which increases the stressful nature of an already potentially nerve-wracking process for the trainee. Though each applicant has unique strengths and thus the process is somewhat individualized, there are some basic principles that can render an applicant more competitive for a gastroenterology fellowship. These include establishing mentorship, achieving scholarly work, building your resume, honing interpersonal and networking skills, and writing a well-planned application. The goal of this article is to outline some basic principles that will help improve the competitiveness of an applicant, and also highlight some practical tips and tricks for applicants with diverse backgrounds, such as international medical graduates, minority applicants, and women in medicine.
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http://dx.doi.org/10.1007/s10620-020-06293-4DOI Listing
August 2020

How to Become a Competitive Applicant for Gastroenterology Fellowship: Tips and Tricks for Success Part I.

Dig Dis Sci 2020 07;65(7):1895-1898

Division of Gastroenterology, Hepatology and Nutrition, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, USA.

In recent years, gastroenterology has become one of the most competitive subspecialties included in the internal medicine fellowship match, which increases the stressful nature of an already potentially nerve-wracking process for the trainee. Though each applicant has unique strengths and thus the process is somewhat individualized, there are some basic principles that can render an applicant more competitive for a gastroenterology fellowship. These include establishing mentorship, achieving scholarly work, building your resume, honing interpersonal and networking skills, and a writing a well-planned application. The goal of this article is to outline some basic principles that will help improve the competitiveness of an applicant, and also highlight some practical tips and tricks for applicants with diverse backgrounds, such as international medical graduates, minority applicants, and women in medicine.
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http://dx.doi.org/10.1007/s10620-020-06292-5DOI Listing
July 2020

Case of acute mixed liver injury due to hypothyroidism.

BMJ Case Rep 2018 Jan 23;2018. Epub 2018 Jan 23.

Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, USA.

The effects of hypothyroidism on the liver are not well understood. A 77-year-old woman with Hashimoto's thyroiditis had stopped taking levothyroxine on her own for 6 months. Her thyroid stimulating hormone (TSH) level was consistent with severe hypothyroidism. She resumed thyroid replacement therapy. The following month, her liver function tests were significantly elevated. Seven weeks after resumption of therapy, her TSH and liver tests had returned to normal. We attribute the mixed hepatocellular injury to hypothyroidism that resolved on correction of the hypothyroid state. This case reminds us that thyroid disease should be considered when evaluating acute liver injury.
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http://dx.doi.org/10.1136/bcr-2017-222373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786968PMC
January 2018
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