Publications by authors named "Nikita B Gadekar"

2 Publications

  • Page 1 of 1

Forensic application of frontal sinus measurement among the Indian population.

J Oral Maxillofac Pathol 2019 Jan-Apr;23(1):147-151

Department of Oral Pathology and Microbiology, Maratha Mandal's NGH Institute of Dental Sciences and Research Centre, Belgaum, Karnataka, India.

Aim: Studies have been done in diversified population, demonstrating the uniqueness of frontal sinus; data related to the Indian population are less. Thus, the present study was aimed to determine the frontal sinus measurement and to assess its forensic application in the Indian population.

Materials And Methods: A total of 400 individuals with Indian origin (21-30 years) were included in the study. The digitized posteroanterior skull radiographs were obtained and was transferred to Adobe CS4 extended to measure the dimensions of frontal sinus and orbit for 12 parameters.

Statistical Analysis: A descriptive statistical analysis was performed.

Results: The descriptive statistics showed the presence of bilateral frontal sinus in 87.7% and bilateral absence in 8.0% of the individuals and the absence of left and right frontal sinus in 3.3% and 1%, respectively. Maximum population showed high asymmetry index (64.7%); the right side frontal sinus (height, 59.3% and width, 40.8%) was superior to the left side in both males and females. The partial septa among the Indian population were absent for maximum population (55.2%), and supraorbital cells of the frontal sinuses were present on both sides among the Indian population.

Conclusion: The observation of the present study suggests that the frontal sinus is highly asymmetrical and unique to the individual and hence can be effectively used in personal identification method in forensic anthropology.
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http://dx.doi.org/10.4103/jomfp.JOMFP_214_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503804PMC
May 2019

Detection of antibodies against Aggregatibacter actinomycetemcomitans in serum and saliva through ELISA in periodontally healthy individuals and individuals with chronic periodontitis.

Microb Pathog 2018 Dec 9;125:438-442. Epub 2018 Oct 9.

Department of Molecular Biology & Immunology, Maratha Mandal's NGH Institute of Dental Sciences and Research Centre, Belgaum, 590010, Karnataka, India.

Background: Periodontitis is a persistent polymicrobial infection, which leads to chronic inflammation in the tooth supporting tissues. Aggregatibacter actinomycetemcomitans are normal commensals of oral cavity but are low in number in periodontally healthy subjects. They are one of the major pathogens aetiologically linked to periodontal disease. Plasma and salivary antibody measurement may be useful to support diagnosis, disease activity, classification and prognosis of periodontitis. The aim of the present study was to investigate the association between the serum and salivary antibody levels to A. actinomycetemcomitans and therefore, to find whether this association was varying in different grades of periodontitis.

Method: Total of 50 periodontally healthy and 50 chronic periodontitis subjects (35-65 years) of both sexes were included for the study. 2 ml of un-stimulated saliva and 5 ml of venous blood was collected under sterile conditions. The detection of antibodies against A. actinomycetemcomitans in periodontally healthy individuals and individuals with chronic periodontitis was performed using indirect ELISA.

Results: Results showed serum IgG, IgA mean levels against A. actinomycetemcomitans were higher in chronic periodontitis subjects compared to mean levels in periodontally healthy subjects. Similarly, salivary IgG, IgA levels were also raised in chronic periodontitis patients as compared in healthy subjects. Also the mean levels of serum IgG and salivary IgA were increased as the severity of disease increased.

Conclusion: Antibody titer using saliva and serum could be useful tool for screening of patients with chronic periodontitis. Further, monitoring the various phases of treatment outcome using saliva could be a useful, non-invasive, prognostic indicator.
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http://dx.doi.org/10.1016/j.micpath.2018.10.007DOI Listing
December 2018
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