Publications by authors named "Nigel P Mongan"

85Publications

Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers.

Biomedicines 2021 Jan 8;9(1). Epub 2021 Jan 8.

Translational Oncology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, Nottingham NG5 1PB, UK.

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January 2021

Molecular Characterisation of Canine Osteosarcoma in High Risk Breeds.

Cancers (Basel) 2020 Aug 25;12(9). Epub 2020 Aug 25.

School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham LE12 5RD, UK.

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August 2020

Lipidomic Biomarkers in Polycystic Ovary Syndrome and Endometrial Cancer.

Int J Mol Sci 2020 Jul 3;21(13). Epub 2020 Jul 3.

Division of Obstetrics and Gynaecology and Child Health, School of Medicine, Faculty of Medicine and Health Sciences, University of Nottingham, Queen's Medical Centre, Nottingham University Hospital, Derby Road, Nottingham NG7 2UH, UK.

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July 2020

Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival.

Breast Cancer Res Treat 2020 Jul 22;182(2):267-282. Epub 2020 May 22.

Nottingham Breast Cancer Research Centre, School of Medicine, University of Nottingham, Nottingham, UK.

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July 2020

A novel prognostic two-gene signature for triple negative breast cancer.

Mod Pathol 2020 11 13;33(11):2208-2220. Epub 2020 May 13.

Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UK.

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November 2020

Prognostic significance of KN motif and ankyrin repeat domains 1 (KANK1) in invasive breast cancer.

Breast Cancer Res Treat 2020 Jan 2;179(2):349-357. Epub 2019 Nov 2.

Division of Cancer and Stem Cells, School of Medicine, Nottingham City Hospital, The University of Nottingham, Nottingham, UK.

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January 2020

The prognostic significance of wild-type isocitrate dehydrogenase 2 (IDH2) in breast cancer.

Breast Cancer Res Treat 2020 Jan 10;179(1):79-90. Epub 2019 Oct 10.

Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UK.

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January 2020

Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer.

Br J Cancer 2019 10 27;121(9):776-785. Epub 2019 Sep 27.

Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham and Nottingham University Hospital NHS Trust, Nottingham, UK.

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October 2019

Metadherin: A Therapeutic Target in Multiple Cancers.

Front Oncol 2019 3;9:349. Epub 2019 May 3.

Department of Biotechnology, Thapar Institute of Engineering and Technology, Patiala, India.

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May 2019

Detection and analysis of RNA methylation.

F1000Res 2019 26;8. Epub 2019 Apr 26.

School of Veterinary Medicine and Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.

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June 2020

Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer.

Breast Cancer Res Treat 2019 Apr 15;174(2):387-399. Epub 2018 Dec 15.

Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UK.

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April 2019

CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.

J Mol Biol 2018 10 25;430(21):4168-4182. Epub 2018 Aug 25.

Department of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY, USA. Electronic address:

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October 2018

The dog as an animal model for bladder and urethral urothelial carcinoma: Comparative epidemiology and histology.

Oncol Lett 2018 Aug 30;16(2):1641-1649. Epub 2018 May 30.

School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, LE12 5RD, UK.

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August 2018

Impact of breast cancer grade discordance on prediction of outcome.

Histopathology 2018 Dec 19;73(6):904-915. Epub 2018 Sep 19.

Department of Histopathology, South Austin Hospital, Austin, TX, USA.

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December 2018

Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development.

Placenta 2017 Aug 20;56:79-85. Epub 2017 Feb 20.

Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Health Sciences, University of Nottingham, LE12 5RD, UK; Department of Pharmacology, Weill Cornell Medicine, New York 10065, USA. Electronic address:

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August 2017

HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells.

Mol Cancer 2017 02 16;16(1):38. Epub 2017 Feb 16.

SVMS, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.

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February 2017

Multiple Genetic Associations with Irish Wolfhound Dilated Cardiomyopathy.

Biomed Res Int 2016 13;2016:6374082. Epub 2016 Dec 13.

Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK.

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February 2017

mA potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination.

Nature 2016 12 30;540(7632):301-304. Epub 2016 Nov 30.

School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

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December 2016

Malignant inflammation in cutaneous T-cell lymphoma-a hostile takeover.

Semin Immunopathol 2017 04 7;39(3):269-282. Epub 2016 Oct 7.

Department of Immunology and Microbiology, University of Copenhagen, Blegdamsvej 3c, DK-2200, Copenhagen N, Denmark.

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April 2017

Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma.

Clin Cancer Res 2016 06 18;22(11):2791-801. Epub 2016 Jan 18.

Department of Pharmacology, Weill Cornell Medical College (WCMC) of Cornell University, New York, New York. Meyer Cancer Center, WCMC of Cornell University, New York, New York.

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June 2016

MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.

Oncotarget 2015 Nov;6(34):35710-25

Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, United Kingdom.

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November 2015

Androgen insensitivity syndrome.

Best Pract Res Clin Endocrinol Metab 2015 Aug 26;29(4):569-80. Epub 2015 Apr 26.

Department of Paediatrics, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, UK. Electronic address:

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August 2015

Genetics of Human and Canine Dilated Cardiomyopathy.

Int J Genomics 2015 22;2015:204823. Epub 2015 Jul 22.

Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK.

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August 2015

Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.

Exp Hematol 2015 Sep 16;43(9):781-93.e2. Epub 2015 May 16.

Cork Cancer Research Centre, Leslie C. Quick, Jr., Laboratory, Biosciences Institute, University College Cork, Cork, Ireland. Electronic address:

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September 2015

Regulation of vascular endothelial growth factor in prostate cancer.

Endocr Relat Cancer 2015 Jun 13;22(3):R107-23. Epub 2015 Apr 13.

Faculty of Medicine and Health SciencesSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Nottingham LE12 5RD, UKDepartment of PharmacologySchool of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UKCancer BiologyDivision of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UKDepartment of International HealthImmunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkClinical Research CenterLund University, Malmö, SwedenDepartment of PharmacologyWeill Cornell Medical College, New York, New York 10065, USA Faculty of Medicine and Health SciencesSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Nottingham LE12 5RD, UKDepartment of PharmacologySchool of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UKCancer BiologyDivision of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UKDepartment of International HealthImmunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkClinical Research CenterLund University, Malmö, SwedenDepartment of PharmacologyWeill Cornell Medical College, New York, New York 10065, USA

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June 2015

A predictive model for canine dilated cardiomyopathy-a meta-analysis of Doberman Pinscher data.

PeerJ 2015 26;3:e842. Epub 2015 Mar 26.

School of Veterinary Medicine and Science, Sutton Bonington Campus, University of Nottingham , Leicestershire , UK.

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April 2015

The role of HIF1α in renal cell carcinoma tumorigenesis.

J Mol Med (Berl) 2014 Aug 12;92(8):825-36. Epub 2014 Jun 12.

Department of Pharmacology, Weill Cornell Medical College (WCMC) of Cornell University, New York, NY, 10065, USA,

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August 2014

Retinoid receptor signaling and autophagy in acute promyelocytic leukemia.

Exp Cell Res 2014 May 30;324(1):1-12. Epub 2014 Mar 30.

Faculty of Medicine and Health Science, School of Veterinary Medicine and Science, University of Nottingham, LE12 5RD, United Kingdom; Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA.. Electronic address:

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May 2014

Molecular characterization of adipose tissue in the African elephant (Loxodonta africana).

PLoS One 2014 14;9(3):e91717. Epub 2014 Mar 14.

Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, Sutton Bonington Campus, University of Nottingham, Sutton Bonington, United Kingdom.

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December 2014

Expression of cyclin d1 and its association with disease characteristics in bladder cancer.

Anticancer Res 2013 Dec;33(12):5235-42

Division of Experimental Cancer Research, Department of Laboratory Medicine in Malmö, Lund University, Clinical Research Center, 205 02, Malmö, Sweden. Tel: +46 40391106,

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December 2013

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.

Nucleic Acids Res 2013 Nov 23;41(21):9663-79. Epub 2013 Aug 23.

Gene Regulation Group, Centre for Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK, School of Psychology, University of Nottingham, Nottingham NG7 2RD, UK and School of Veterinary Medicine and Science, University of Nottingham, Nottingham NG7 2RD, UK.

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November 2013

Expression of VEGF and its receptors VEGFR1/VEGFR2 is associated with invasiveness of bladder cancer.

Anticancer Res 2013 Jun;33(6):2381-90

Section for Experimental Cancer Research, Department of Laboratory Medicine in Malmö, Lund University, Clinical Research Center, 205 02 Malmö, Sweden.

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June 2013

Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.

Nucleic Acids Res 2013 Jul 10;41(13):6430-43. Epub 2013 May 10.

Department of Pharmacology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, NY 10065, USA.

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July 2013

CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.

Cell Cycle 2013 Apr 21;12(8):1251-66. Epub 2013 Mar 21.

Department of Laboratory Medicine, Division of Experimental Cancer Research, Clinical Research Center, Lund University, Malmö, Sweden.

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April 2013

Reduced neonatal mortality in Meishan piglets: a role for hepatic fatty acids?

PLoS One 2012 14;7(11):e49101. Epub 2012 Nov 14.

School of Veterinary Medicine and Science, University of Nottingham, Leicestershire, United Kingdom.

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May 2013

Overcoming drug resistance and treating advanced prostate cancer.

Curr Drug Targets 2012 Sep;13(10):1308-23

Division of Experimental Cancer Research, Department of Laboratory Medicine, Lund University, Clinical ResearchCentre in Malmö, Malmo, Sweden.

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September 2012

Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies.

Cancer Biol Ther 2010 May 8;9(9):678-84. Epub 2010 May 8.

Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College - New York Presbyterian Hospital, New York, NY, USA.

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May 2010

Diverse actions of retinoid receptors in cancer prevention and treatment.

Differentiation 2007 Nov 18;75(9):853-70. Epub 2007 Jul 18.

Department of Pharmacology, Weill Cornell Medical College, New York, NY 10021, USA.

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November 2007

The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures.

Mol Carcinog 2006 Dec;45(12):887-900

Department of Pharmacology, Weill Medical College, Cornell University, New York, New York 10021, USA.

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December 2006

Five novel androgen receptor gene mutations associated with complete androgen insensitivity syndrome.

Hum Mutat 2006 Mar;27(3):291

Department of Paediatrics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.

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March 2006

Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder.

Clin Cancer Res 2005 Dec;11(24 Pt 1):8570-6

Department of Urology, The New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York 10021, USA.

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December 2005

Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma.

Carcinogenesis 2006 Mar 12;27(3):499-507. Epub 2005 Dec 12.

Department of Urology, The New York-Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY, USA.

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March 2006

Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.

Mol Cancer Ther 2005 Mar;4(3):477-86

Department of Pharmacology, Weill Medical College, Cornell University, 1300 York Avenue, New York, NY 10021, USA.

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March 2005

Retinoid receptor mRNA expression profiles in human bladder cancer specimens.

Int J Oncol 2005 Apr;26(4):1041-8

Department of Urology, New York Presbyterian Hospital-Weill-Cornell Medical Center, 1300 York Avenue, New York, NY 10021, USA.

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April 2005

Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer.

Urology 2004 Aug;64(2):383-8

Department of Urology, New York Presbyterian Hospital-Weill-Cornell Medical Center, New York, New York, USA.

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August 2004

Evidence that luteinising hormone receptor polymorphisms may contribute to male undermasculinisation.

Eur J Endocrinol 2002 Jul;147(1):103-7

Department of Paediatrics, University of Cambridge, Box 116, Level 8, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK.

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July 2002

Novel alpha7-like nicotinic acetylcholine receptor subunits in the nematode Caenorhabditis elegans.

Protein Sci 2002 May;11(5):1162-71

MRC Functional Genetics Unit, Department of Human Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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May 2002

Two de novo mutations in the AR gene cause the complete androgen insensitivity syndrome in a pair of monozygotic twins.

J Clin Endocrinol Metab 2002 Mar;87(3):1057-61

University Department of Pediatrics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom CB2 2QQ.

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March 2002