Nigel P Groome

Nigel P Groome

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Nigel P Groome

Nigel P Groome

Publications by authors named "Nigel P Groome"

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Activin over-expression in the testis of mice lacking the inhibin α-subunit gene is associated with androgen deficiency and regression of the male reproductive tract.

Mol Cell Endocrinol 2018 07 28;470:188-198. Epub 2017 Oct 28.

Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1016/j.mce.2017.10.013DOI Listing
July 2018

A new 'total' activin B enzyme-linked immunosorbent assay (ELISA): development and validation for human samples.

Clin Endocrinol (Oxf) 2009 Dec 28;71(6):867-73. Epub 2009 May 28.

Centre for Proteins and Peptides, School of Life Sciences, Oxford Brookes University, Headington, Oxford, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2009.03567.xDOI Listing
December 2009

Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients.

Clin Cancer Res 2008 Aug;14(16):5228-35

YCR and Liz Dawn Pathology and Translational Sciences Centre, Leeds Teaching Hospitals and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-4528DOI Listing
August 2008

Evaluation of the relationship between follicular fluid oxidative stress, ovarian hormones, and response to gonadotropin stimulation.

Fertil Steril 2008 Apr 6;89(4):912-21. Epub 2007 Aug 6.

Academic Department of Obstetrics and Gynaecology, Royal Free and University College London, University College London Campus, London, United Kingdom.

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http://dx.doi.org/10.1016/j.fertnstert.2007.04.034DOI Listing
April 2008

Development of a new antibody to the human inhibin/activin betaB subunit and its application to improved inhibin B ELISAs.

J Immunol Methods 2008 Jan 23;329(1-2):102-11. Epub 2007 Oct 23.

Centre for Proteins and Peptides, School of Life Sciences, Oxford Brookes University, Headington, Oxford, OX3 0BP, UK.

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http://dx.doi.org/10.1016/j.jim.2007.09.013DOI Listing
January 2008

Human fetal testis Leydig cell disruption by exposure to the pesticide dieldrin at low concentrations.

Hum Reprod 2007 Nov 11;22(11):2919-27. Epub 2007 Sep 11.

Department of Obstetrics and Gynaecology, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.

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http://dx.doi.org/10.1093/humrep/dem256DOI Listing
November 2007

Rising follicle-stimulating hormone levels with age accelerate female reproductive failure.

Endocrinology 2007 Sep 31;148(9):4432-9. Epub 2007 May 31.

ANZAC Research Institute, University of Sydney, Concord Hospital, New South Wales, 2139 Australia.

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http://dx.doi.org/10.1210/en.2007-0046DOI Listing
September 2007

Deregulation of the activin/follistatin system in hepatocarcinogenesis.

J Hepatol 2006 Nov 28;45(5):673-80. Epub 2006 Jul 28.

Department of Medicine I, Division: Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.jhep.2006.06.014DOI Listing
November 2006

Serum anti-mullerian hormone levels reflect the size of the primordial follicle pool in mice.

Endocrinology 2006 Jul 23;147(7):3228-34. Epub 2006 Mar 23.

Department of Internal Medicine, Erasmus MC, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/en.2005-1588DOI Listing
July 2006

Bovine follicle development is associated with divergent changes in activin-A, inhibin-A and follistatin and the relative abundance of different follistatin isoforms in follicular fluid.

J Endocrinol 2006 Feb;188(2):215-25

School of Biological Sciences, The University of Reading, Whiteknights, Reading RG6 6AJ, UK.

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http://dx.doi.org/10.1677/joe.1.06485DOI Listing
February 2006

Anti-müllerian hormone protein expression is reduced during the initial stages of follicle development in human polycystic ovaries.

J Clin Endocrinol Metab 2005 Oct 19;90(10):5536-43. Epub 2005 Jul 19.

Institute of Reproductive and Developmental Biology, Wolfson and Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1210/jc.2005-0907DOI Listing
October 2005

ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.

J Pathol 2005 Sep;207(1):53-60

Cancer Research UK Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.

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http://doi.wiley.com/10.1002/path.1807
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http://dx.doi.org/10.1002/path.1807DOI Listing
September 2005

Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells.

Endocrinology 2005 Aug 5;146(8):3547-57. Epub 2005 May 5.

Division of Endocrinology, Metabolism, and Molecular Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th Street, Los Angeles, California 90059, USA.

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http://dx.doi.org/10.1210/en.2005-0362DOI Listing
August 2005

Follicular and hormonal dynamics during the estrous cycle in goats.

J Reprod Dev 2005 Aug;51(4):455-63

Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Japan.

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http://dx.doi.org/10.1262/jrd.17017DOI Listing
August 2005

Evidence for increased ovarian follicular activity in girls with premature thelarche.

Clin Endocrinol (Oxf) 2005 Feb;62(2):205-9

Department of Paediatric Biochemistry, Royal Hospital for Sick Children, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2004.02198.xDOI Listing
February 2005

Adenoviral gene transfer allows Smad-responsive gene promoter analyses and delineation of type I receptor usage of transforming growth factor-beta family ligands in cultured human granulosa luteal cells.

J Clin Endocrinol Metab 2005 Jan 13;90(1):271-8. Epub 2004 Oct 13.

Program for Developmental and Reproductive Biology, Biomedicum Helsinki and Department of Bacteriology, Haartman Institute, University of Helsinki, Haartmaninkatu 8, 00014 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2004-1288DOI Listing
January 2005

Cell-specific expression of betaC-activin in the rat reproductive tract, adrenal and liver.

Mol Cell Endocrinol 2004 Jul;222(1-2):61-9

Department of Anatomy and Structural Biology and Centre for Gene Research, University of Otago, School of Medical Sciences, P.O. Box 913, Dunedin, New Zealand.

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http://dx.doi.org/10.1016/j.mce.2004.05.007DOI Listing
July 2004

Activin betaC-subunit heterodimers provide a new mechanism of regulating activin levels in the prostate.

Endocrinology 2003 Oct 26;144(10):4410-9. Epub 2003 Jun 26.

Monash Institute of Reproduction and Development, Monash University, Melbourne, Victoria 3168, Australia.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2003-0225DOI Listing
October 2003

Ovarian dynamics and their associations with peripheral concentrations of gonadotropins, ovarian steroids, and inhibin during the estrous cycle in goats.

Biol Reprod 2003 Jul 5;69(1):57-63. Epub 2003 Feb 5.

Department of Theriogenology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.

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http://dx.doi.org/10.1095/biolreprod.102.013334DOI Listing
July 2003

Inhibin B regulating follicle-stimulating hormone secretion during testicular recrudescence in the male golden hamster.

J Androl 2002 Nov-Dec;23(6):845-53

Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University, Japan.

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May 2003

Concentrations of serum total activin A and inhibin A in preterm and term labor patients: a cross-sectional study.

J Soc Gynecol Investig 2003 May;10(4):231-6

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1016/s1071-5576(03)00047-9DOI Listing
May 2003

Changes in activin and activin receptor subunit expression in rat liver during the development of CCl4-induced cirrhosis.

Mol Cell Endocrinol 2003 Mar;201(1-2):143-53

Department of Anatomy and Structural Biology and Centre for Gene Research, University of Otago, Otago School of Medical Sciences, P.O. Box 913, Dunedin, New Zealand.

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http://dx.doi.org/10.1016/s0303-7207(02)00417-3DOI Listing
March 2003

Growth differentiation factor-9 induces Smad2 activation and inhibin B production in cultured human granulosa-luteal cells.

J Clin Endocrinol Metab 2003 Feb;88(2):755-62

Program for Developmental and Reproductive Biology, Biomedicum Helsinki, and Department of Bacteriology, Haartman Institute, University of Helsinki, 00014 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2002-021317DOI Listing
February 2003

Localization and secretion of inhibins in the equine fetal ovaries.

Biol Reprod 2003 Jan;68(1):328-35

Department of Basic Veterinary Science, The United Graduate School of Veterinary Science, Gifu University, Gifu 501-1193, Japan.

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http://dx.doi.org/10.1095/biolreprod.102.003749DOI Listing
January 2003

Maternal serum activin, inhibin, human chorionic gonadotrophin and alpha-fetoprotein as second trimester predictors of pre-eclampsia.

BJOG 2003 Jan;110(1):46-52

Obstetrics and Gynaecology, Department of Reproductive and Developmental Sciences, University of Edinburgh, UK.

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January 2003

Differential expression of two estrogen receptor beta isoforms in the human fetal testis during the second trimester of pregnancy.

J Clin Endocrinol Metab 2003 Jan;88(1):424-32

MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, Edinburgh EH16 4SB, United Kingdom.

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http://dx.doi.org/10.1210/jc.2002-020811DOI Listing
January 2003

Steroid receptor expression in uterine natural killer cells.

J Clin Endocrinol Metab 2003 Jan;88(1):440-9

Obstetrics and Gynaecology Section, Department of Reproductive and Developmental Sciences, Centre for Reproductive Biology, Edinburgh, EH16 4SB, United Kingdom.

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http://dx.doi.org/10.1210/jc.2002-021174DOI Listing
January 2003

Human oestrogen receptors: differential expression of ER alpha and beta and the identification of ER beta variants.

Steroids 2002 Nov;67(12):985-92

MRC Human Reproductive Sciences Unit, The University of Edinburgh Medical School, EH16 4SB, Edinburgh, UK.

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http://dx.doi.org/10.1016/s0039-128x(02)00047-8DOI Listing
November 2002

Wild-type estrogen receptor (ERbeta1) and the splice variant (ERbetacx/beta2) are both expressed within the human endometrium throughout the normal menstrual cycle.

J Clin Endocrinol Metab 2002 Nov;87(11):5265-73

Obstetrics and Gynecology Section, Department of Reproductive and Developmental Sciences, Center for Reproductive Biology, University of Edinburgh Medical School, Little France Cresent, Edinburgh, Scotland, UK EH16 4SB.

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http://dx.doi.org/10.1210/jc.2002-020502DOI Listing
November 2002

The testis as a major source of circulating inhibins in the male equine fetus during the second half of gestation.

J Androl 2002 Mar-Apr;23(2):229-36

Department of Basic Veterinary Science, The United Graduate School of Veterinary Science, Gifu University, Japan.

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August 2002

ERbeta1 and the ERbeta2 splice variant (ERbetacx/beta2) are expressed in distinct cell populations in the adult human testis.

J Clin Endocrinol Metab 2002 Jun;87(6):2706-15

Medical Research Council Human Reproductive Sciences Unit, Centre for Reproductive Biology, 37 Chalmers Street, Edinburgh EH3 9ET, Scotland, UK.

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http://dx.doi.org/10.1210/jcem.87.6.8619DOI Listing
June 2002

Serum activin A, inhibin A, and follistatin concentrations in preeclampsia or small for gestational age pregnancies.

Obstet Gynecol 2002 Feb;99(2):267-74

Liggins Institute and Division of Pharmacology and Clinical Pharmacology, University of Auckland, Faculty of Medical and Health Sciences, New Zealand.

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http://dx.doi.org/10.1016/s0029-7844(01)01674-xDOI Listing
February 2002

High serum concentrations of dimeric inhibins A and B in normal newborn girls.

Fertil Steril 2002 Feb;77(2):363-5

Centro de Investigaciones Endocrinológicas, R. Gutierrez Hospital de Niños, Gallo 1330, 1425 Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/s0015-0282(01)02965-xDOI Listing
February 2002