Nigel K Arden

Nigel K Arden

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Nigel K Arden

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Prevalence of and Risk Factors for Total Hip and Knee Replacement in Retired National Football League Athletes.

Am J Sports Med 2019 Oct 9;47(12):2863-2870. Epub 2019 Sep 9.

MOTION Science Institute, Department of Exercise and Sport Science, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1177/0363546519870804DOI Listing
October 2019

ACL and meniscal injuries increase the risk of primary total knee replacement for osteoarthritis: a matched case-control study using the Clinical Practice Research Datalink (CPRD).

Br J Sports Med 2019 Aug 13;53(15):965-968. Epub 2018 Jan 13.

NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/bjsports-2017-097762DOI Listing
August 2019

The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis.

J Rheumatol 2019 Aug 15;46(8):981-989. Epub 2019 Jan 15.

From the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, and UK National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford; Institute of Translational Medicine, University of Liverpool, Liverpool; Faculty of Health and Medical Sciences, University of Surrey, Guildford; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; NIHR Leeds Biomedical Research Centre, Leeds, UK; Department of Medicine, Faculty of Medicine, and Institute of Health Policy, Management, and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto; Division of Rheumatology, Department of Medicine, and School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; Institute of Bone and Joint Research, Department of Rheumatology, School of Medicine, University of Sydney and Royal North Shore Hospital; Inner West Psychology; School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, Australia; Department of Epidemiology and Biostatistics, Amsterdam University Medical Centers, location VUmc; Amsterdam University Medical Centre, Department of Medical Humanities, Amsterdam Public Health, Amsterdam; Departments of Rheumatology and Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Bispebjerg and Frederiksberg Hospital, and Department of Rheumatology, Odense University Hospital; Center for Muscle and Joint Health, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark; Université de Lorraine, Approches Épidémiologiques et Psychologiques (APEMAC), Nancy, France; Division of Rheumatology, Allergy and Immunology, Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, North Carolina; Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Sections of Clinical Epidemiology and Rheumatology, Boston University School of Medicine, Boston, Massachusetts; TissueGene Inc., Rockville; Division of Rheumatology and Clinical Immunology, Department of Medicine and Division of Gerontology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA; Merck Biopharma, Merck KGaA, Darmstadt; University Pain Centre, University Hospital Carl Gustav Carus, Dresden, Germany; Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania; Faculty of Humanities and Social Sciences, University of Lucerne, Lucerne, Switzerland.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.181194
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http://dx.doi.org/10.3899/jrheum.181194DOI Listing
August 2019

Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017.

J Rheumatol 2019 Aug 1;46(8):976-980. Epub 2019 Mar 1.

From the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford; School of Health and Social Care, London South Bank University, London; Institute of Translational Medicine, University of Liverpool, Liverpool; Faculty of Health and Medical Sciences, University of Surrey, Guildford; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research (NIHR) Leeds Biomedical Research Centre (BRC), Leeds, UK; Department of Medicine, Faculty of Medicine, and Institute of Health Policy, Management, and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto; Division of Rheumatology, Department of Medicine, and School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; Institute of Bone and Joint Research, Department of Rheumatology, School of Medicine, University of Sydney and Royal North Shore Hospital, Sydney, Australia; Department of Epidemiology and Biostatistics, Amsterdam University Medical Centres, location VUmc; Amsterdam University Medical Centre, Department of Medical Humanities, Amsterdam Public Health, Amsterdam; Departments of Rheumatology and Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands; Musculoskeletal Statistics Unit, the Parker Institute, Bispebjerg and Frederiksberg Hospital and Department of Rheumatology, Odense University Hospital; Center for Muscle and Joint Health, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark; Université de Lorraine, APEMAC, Nancy, France; Division of Rheumatology, Allergy and Immunology, Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, North Carolina; Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago; Sections of Clinical Epidemiology and Rheumatology, Boston University School of Medicine, Boston; TissueGene Inc., Rockville; Division of Rheumatology and Clinical Immunology, Department of Medicine and Division of Gerontology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA; Merck Biopharma, Merck KGaA, Darmstadt; University Pain Centre, University Hospital Carl Gustav Carus, Dresden, Germany; Inner West Psychology; Institute of Bone and Joint Research, Department of Rheumatology, School of Medicine, University of Sydney and Royal North Shore Hospital; School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, Australia; Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania; Faculty of Humanities and Social Sciences, University of Lucerne, Lucerne, Switzerland.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.181066
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http://dx.doi.org/10.3899/jrheum.181066DOI Listing
August 2019

The prevalence of hand and wrist osteoarthritis in elite former cricket and rugby union players.

J Sci Med Sport 2019 Aug 16;22(8):871-875. Epub 2019 Mar 16.

Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Botnar Research Centre, UK.

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http://dx.doi.org/10.1016/j.jsams.2019.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593259PMC
August 2019

Descriptive epidemiology of hip and knee replacement in rheumatoid arthritis: an analysis of UK electronic medical records.

Semin Arthritis Rheum 2019 Aug 26. Epub 2019 Aug 26.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom; GREMPAL Research Group, Idiap Jordi Gol and CIBERFes, Unviersitat Autonoma de Barcelona and Insituto de Salud Carlos III, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.semarthrit.2019.08.008DOI Listing
August 2019

Measurement of synovial tissue volume in knee osteoarthritis using a semiautomated MRI-based quantitative approach.

Magn Reson Med 2019 05 15;81(5):3056-3064. Epub 2019 Feb 15.

Centre for Imaging Sciences, Division of Informatics, Imaging and Data Science, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1002/mrm.27633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686166PMC
May 2019

Lifetime risk of knee and hip replacement following a diagnosis of RA: findings from a cohort of 13 961 patients from England.

Rheumatology (Oxford) 2019 May 23. Epub 2019 May 23.

GREMPAL Research Group, Idiap Jordi Gol and CIBERFes, Universitat Autonoma de Barcelona and Instituto de Salud Carlos III, Barcelona, Spain.

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http://dx.doi.org/10.1093/rheumatology/kez223DOI Listing
May 2019

Predicting incident radiographic knee osteoarthritis in middle-aged women within 4 years: the importance of knee-level prognostic factors.

Arthritis Care Res (Hoboken) 2019 May 25. Epub 2019 May 25.

Botnar Research Centre. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford. Oxford, UK.

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http://dx.doi.org/10.1002/acr.23932DOI Listing
May 2019

Dominant vs. non-dominant hip comparison in bone mineral density in young sporting athletes.

Arch Osteoporos 2019 May 25;14(1):54. Epub 2019 May 25.

Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://link.springer.com/10.1007/s11657-019-0605-2
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http://dx.doi.org/10.1007/s11657-019-0605-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535155PMC
May 2019

An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).

Semin Arthritis Rheum 2019 Apr 30. Epub 2019 Apr 30.

Division of Public Health, Epidemiology and Health Economics, University of Liège, CHU Sart Tilman, 4000, Liège, Belgium; WHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Liège, Belgium; Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.1016/j.semarthrit.2019.04.008DOI Listing
April 2019

Lifetime risk of knee and hip replacement following a diagnosis of RA: findings from a cohort of 13 961 patients from England.

Rheumatology (Oxford) 2019 Apr 23. Epub 2019 Apr 23.

GREMPAL Research Group, Idiap Jordi Gol and CIBERFes, Universitat Autonoma de Barcelona and Instituto de Salud Carlos III, Barcelona, Spain.

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http://dx.doi.org/10.1093/rheumatology/kez143DOI Listing
April 2019

Predictors of return to desired activity 12 months following unicompartmental and total knee arthroplasty.

Acta Orthop 2019 Feb 19;90(1):74-80. Epub 2018 Nov 19.

b Arthritis Research UK Centre for Sport , Exercise and Osteoarthritis, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences , University of Oxford, Botnar Research Centre , Oxford , UK ;

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http://dx.doi.org/10.1080/17453674.2018.1542214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366469PMC
February 2019

Effect of Vitamin D supplementation on synovial tissue volume and subchondral bone marrow lesion volume in symptomatic knee osteoarthritis.

BMC Musculoskelet Disord 2019 Feb 14;20(1):76. Epub 2019 Feb 14.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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https://bmcmusculoskeletdisord.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12891-019-2424-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376763PMC
February 2019

UK podiatrists' experiences of podiatry services for people living with arthritis: a qualitative investigation.

J Foot Ankle Res 2018 5;11:27. Epub 2018 Jun 5.

1Faculty of Health Sciences, University of Southampton, Highfield Campus Building 45, University Road, Southampton, Hampshire SO17 1BJ UK.

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http://dx.doi.org/10.1186/s13047-018-0262-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989380PMC
October 2018

Risk of Injury in Royal Air Force Training: Does Sex Really Matter?

Mil Med 2018 Aug 21. Epub 2018 Aug 21.

Arthritis Research UK Sports, Exercise and Osteoarthritis Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford, UK.

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http://dx.doi.org/10.1093/milmed/usy177DOI Listing
August 2018

Evaluating Patients' Expectations From a Novel Patient-Centered Perspective Predicts Knee Arthroplasty Outcome.

J Arthroplasty 2018 07 15;33(7):2146-2152.e4. Epub 2018 Feb 15.

Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Botnar Research Centre, Oxford UK.

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http://dx.doi.org/10.1016/j.arth.2018.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005343PMC
July 2018

Osteoarthritis and other long-term health conditions in former elite cricketers.

J Sci Med Sport 2018 Jun 18;21(6):558-563. Epub 2017 Oct 18.

University of Oxford, Botnar Research Centre, UK; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, UK.

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http://dx.doi.org/10.1016/j.jsams.2017.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964309PMC
June 2018

The impact of rheumatoid arthritis on the risk of adverse events following joint replacement: a real-world cohort study.

Clin Epidemiol 2018 14;10:697-704. Epub 2018 Jun 14.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.2147/CLEP.S160347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005318PMC
June 2018

Association between NICE guidance on biologic therapies with rates of hip and knee replacement among rheumatoid arthritis patients in England and Wales: An interrupted time-series analysis.

Semin Arthritis Rheum 2018 04 23;47(5):605-610. Epub 2017 Sep 23.

Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD; GREMPAL Research Group, Idiap Jordi Gol Primary Care Research Institute and CIBERFes, Universitat Autònoma de Barcelona and Instituto de Salud Carlos III, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866918PMC
April 2018

Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial.

Ann Intern Med 2018 03 20;168(6):385-395. Epub 2018 Feb 20.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds, United Kingdom (S.R.K., A.G., R.J.W., P.G.C.).

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http://dx.doi.org/10.7326/M17-1430DOI Listing
March 2018

Development of a model predicting non-satisfaction 1 year after primary total knee replacement in the UK and transportation to Switzerland.

Sci Rep 2018 02 21;8(1):3380. Epub 2018 Feb 21.

Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41598-018-21713-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821704PMC
February 2018

Physical activity in former elite cricketers and strategies for promoting physical activity after retirement from cricket: a qualitative study.

BMJ Open 2017 Nov 17;7(11):e017785. Epub 2017 Nov 17.

Arthritis Research UK Centre for Sport, Exercise & Osteoarthritis, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK.

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-01778
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http://dx.doi.org/10.1136/bmjopen-2017-017785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701977PMC
November 2017

Protective effect of antirheumatic drugs on dementia in rheumatoid arthritis patients.

Alzheimers Dement (N Y) 2017 Nov 9;3(4):612-621. Epub 2017 Nov 9.

Oxford NIHR Biomedical Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/j.trci.2017.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700830PMC
November 2017

Health amongst former rugby union players: A cross-sectional study of morbidity and health-related quality of life.

Sci Rep 2017 09 28;7(1):11786. Epub 2017 Sep 28.

Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, Oxford, UK.

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http://dx.doi.org/10.1038/s41598-017-12130-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620077PMC
September 2017

Common attributes in retired professional cricketers that may enhance or hinder quality of life after retirement: a qualitative study.

BMJ Open 2017 Jul 26;7(7):e016541. Epub 2017 Jul 26.

Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis; Nuffield Department of Orthopaedics, Rheumatologyand Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-01654
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http://dx.doi.org/10.1136/bmjopen-2017-016541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642649PMC
July 2017

The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.

Lancet 2017 04 14;389(10077):1424-1430. Epub 2017 Feb 14.

Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)30059-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522532PMC
April 2017

Cost-Effectiveness of Orthogeriatric and Fracture Liaison Service Models of Care for Hip Fracture Patients: A Population-Based Study.

J Bone Miner Res 2017 Feb 1;32(2):203-211. Epub 2016 Nov 1.

Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://doi.wiley.com/10.1002/jbmr.2995
Publisher Site
http://dx.doi.org/10.1002/jbmr.2995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321497PMC
February 2017

Predictors of Patient-Reported Pain and Functional Outcomes Over 10 Years After Primary Total Knee Arthroplasty: A Prospective Cohort Study.

J Arthroplasty 2017 01 23;32(1):92-100.e2. Epub 2016 Jun 23.

Arthritis Research UK Sports, Exercise and Osteoarthritis Centre of Excellence, University of Oxford, UK; NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1016/j.arth.2016.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178876PMC
January 2017

Determinants of the Maternal 25-Hydroxyvitamin D Response to Vitamin D Supplementation During Pregnancy.

J Clin Endocrinol Metab 2016 12 27;101(12):5012-5020. Epub 2016 Oct 27.

Medical Research Council (MRC) Lifecourse Epidemiology Unit (University of Southampton) (R.J.M., N.C.H., C.C., S.D., S.R.C., H.M.I., E.M.D., K.M.G., S.M.R.), Southampton General Hospital; Paediatric Endocrinology (R.J.M.), University Hospital Southampton NHS Foundation Trust; and National Institute for Health Research (NIHR) Southampton Nutrition Biomedical Research Centre (N.C.H., C.C., K.M.G.), University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, United Kingdom; NIHR Musculoskeletal Biomedical Research Unit (C.C., N.K.A., A.C., M.K.J.), University of Oxford, Oxford OX3 7LD, United Kingdom; MRC Human Nutrition Research (I.S., A.P.), Elsie Widdowson Laboratory, Cambridge, United Kingdom CB1 9NL; Academic Unit of Child Health (N.J.B.), Sheffield Children's Hospital, University of Sheffield, Sheffield, United Kingdom S10 2TH; Academic Unit of Bone Metabolism (R.E.), University of Sheffield, Sheffield, United Kingdom S5 7AU; Sheffield Hospitals NHS Trust (University of Sheffield) (R.F., S.V.G.), Sheffield, United Kingdom S10 2SF; Nuffield Department of Obstetrics and Gynaecology (S.K., A.T.P.), John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom OX3 9DU; Department of Paediatric Endocrinology (M.Z.M.), Royal Manchester Children's Hospitals, Manchester, United Kingdom M13 9WL; and School of Medicine and Dentistry (D.M.R.), Medical School, University of Aberdeen, Aberdeen, United Kingdom AB25 2ZD; Department of Medicine (I.S.), Norwich Medical School, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, United Kingdom NR4 7TJ.

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http://dx.doi.org/10.1210/jc.2016-2869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155676PMC
December 2016

Adipokines as potential prognostic biomarkers in patients with acute knee injury.

Biomarkers 2015 26;20(8):519-25. Epub 2015 May 26.

a Nuffield Department of Orthopaedics , Rheumatology and Musculoskeletal Sciences, University of Oxford , Oxford , UK .

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http://dx.doi.org/10.3109/1354750X.2014.948914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819580PMC
November 2016

Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women.

Biomarkers 2015 5;20(8):557-64. Epub 2016 Feb 5.

a Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford , Oxford , UK .

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http://dx.doi.org/10.3109/1354750X.2015.1105498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819573PMC
November 2016

Anti-Osteoporosis Medication Prescriptions and Incidence of Subsequent Fracture Among Primary Hip Fracture Patients in England and Wales: An Interrupted Time-Series Analysis.

J Bone Miner Res 2016 11 4;31(11):2008-2015. Epub 2016 Jul 4.

Oxford National Institute for Health Research (NIHR) Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/jbmr.2882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122450PMC
November 2016

Association Between Overweight and Obesity and Risk of Clinically Diagnosed Knee, Hip, and Hand Osteoarthritis: A Population-Based Cohort Study.

Arthritis Rheumatol 2016 08;68(8):1869-75

MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK, Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, and University of Oxford, Oxford, UK, and GREMPAL Research Group, IDIAP Jordi Gol Primary Care Research Institute, Universitat Autònoma de Barcelona, RETICEF, IMIM Research Foundation, Parc de Salut Mar, and Instituto de Salud Carlos III, Barcelona, Spain.

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http://dx.doi.org/10.1002/art.39707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966641PMC
August 2016

Harmonising data collection from osteoarthritis studies to enable stratification: recommendations on core data collection from an Arthritis Research UK clinical studies group.

Rheumatology (Oxford) 2016 08 15;55(8):1394-402. Epub 2016 Apr 15.

Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, University of Oxford MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1093/rheumatology/kew201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957675PMC
August 2016

Reply.

Arthritis Rheumatol 2016 06;68(6):1567-8

University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/art.39578DOI Listing
June 2016

Obesity and the Relative Risk of Knee Replacement Surgery in Patients With Knee Osteoarthritis: A Prospective Cohort Study.

Arthritis Rheumatol 2016 Apr;68(4):817-25

University of Oxford, Oxford, UK, FIMIM-Parc Salut Mar and RETICEF, Barcelona, Spain, and GREMPAL Research Group, IDIAP Jordi Gol Primary Care Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/art.39486DOI Listing
April 2016

Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study.

Age Ageing 2016 Mar 21;45(2):236-42. Epub 2016 Jan 21.

Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1093/ageing/afv204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776625PMC
March 2016

Strategies for the prevention of knee osteoarthritis.

Nat Rev Rheumatol 2016 Feb 6;12(2):92-101. Epub 2015 Oct 6.

Botnar Research Centre, Nuffield Orthopedic Centre, Oxford OX3 7LD, UK.

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http://www.esceo.org/sites/esceo/files/publications/nrrheum-
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http://dx.doi.org/10.1038/nrrheum.2015.135DOI Listing
February 2016

Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England.

Br J Sports Med 2016 Feb;50(3):187

National Institute for Health Research Oxford Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Headington, Oxford OX3 7LD, UK MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1136/bjsports-2014-f6549repDOI Listing
February 2016

Incidence and Predictors of Multiple Fractures Despite High Adherence to Oral Bisphosphonates: A Binational Population-Based Cohort Study.

J Bone Miner Res 2016 Jan;31(1):234-44

Oxford National Institute for Health Research (NIHR) Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/jbmr.2595DOI Listing
January 2016

Can the publication of guidelines change the management of early rheumatoid arthritis? An interrupted time series analysis from the United Kingdom.

Rheumatology (Oxford) 2015 Dec 4;54(12):2244-8. Epub 2015 Aug 4.

Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, Department of Rheumatology, University Hospital Southampton NHS Foundation Trust and NIHR Wellcome Trust Clinical Research Facility, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1093/rheumatology/kev268DOI Listing
December 2015

Are guidelines good value for money?

Rheumatology (Oxford) 2015 Dec 27;54(12):2121-3. Epub 2015 Aug 27.

NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton,

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http://dx.doi.org/10.1093/rheumatology/kev308DOI Listing
December 2015

Validation of statistical shape modelling to predict hip osteoarthritis in females: data from two prospective cohort studies (Cohort Hip and Cohort Knee and Chingford).

Rheumatology (Oxford) 2015 Nov 1;54(11):2033-41. Epub 2015 Jul 1.

Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/kev232DOI Listing
November 2015

Raising the quality of rheumatology management recommendations: lessons from the EULAR process 10 years after provision of standard operating procedures.

Rheumatology (Oxford) 2015 Aug 19;54(8):1392-6. Epub 2015 Feb 19.

NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK and

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http://dx.doi.org/10.1093/rheumatology/keu525DOI Listing
August 2015

Variations In Good Patient Reported Outcomes After Total Knee Arthroplasty.

J Arthroplasty 2015 Aug 28;30(8):1364-71. Epub 2015 Feb 28.

Oxford NIHR Musculoskeletal BRU to Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; MRC Life course Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1016/j.arth.2015.02.039DOI Listing
August 2015

Drug utilization in patients with OA: a population-based study.

Rheumatology (Oxford) 2015 May 21;54(5):860-7. Epub 2014 Oct 21.

Institute of Bone and Joint Research, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia, Global Burden of Diseases Study 2010 Working Group, University of Washington, Seattle, WA, USA, Institut d'Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, Departament de Reumatologia, L'Hospitalet de Llobregat, Institut Català de la Salut, Primary Care Department, IDIAP Jordi Gol, SIDIAP Database, Institut Català de la Salut, URFOA-IMIM and RETICEF, Internal Medicine, Parc de Salut Mar-Instituto Carlos III, Barcelona, Spain, Musculoskeletal Epidemiology Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford and MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK Institute of Bone and Joint Research, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia, Global Burden of Diseases Study 2010 Working Group, University of Washington, Seattle, WA, USA, Institut d'Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, Departament de Reumatologia, L'Hospitalet de Llobregat, Institut Català de la Salut, Primary Care Department, IDIAP Jordi Gol, SIDIAP Database, Institut Català de la Salut, URFOA-IMIM and RETICEF, Internal Medicine, Parc de Salut Mar-Instituto Carlos III, Barcelona, Spain, Musculoskeletal Epidemiology Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford and MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK Institute of Bone and Joint Research, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia, Global Burden of Diseases Study 2010 Working Group, University of Washington, Seattle, WA, USA, Institut d'Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, Departament de Reumatologia, L'Hospitalet de Llobregat, Institut Catal

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http://dx.doi.org/10.1093/rheumatology/keu403DOI Listing
May 2015

Inadequate pain relief and large functional loss among patients with knee osteoarthritis: evidence from a prospective multinational longitudinal study of osteoarthritis real-world therapies.

Rheumatology (Oxford) 2015 Feb 23;54(2):270-7. Epub 2014 Aug 23.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK, Clinical Development, MRL, Merck & Co., Kenilworth, Global Health Outcomes, Merck & Co., Whitehouse Station, MedData Analytics, East Brunswick, NJ, College of Pharmacy, St Johns University, Queens, NY, USA, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, Centre for Health Economics, Swansea University, Swansea, UK, Cochin Hospital, Rehabilitation Department, University of Paris, Paris, France, Department of Rheumatology and Clinical Immunology, University of Twente, Enschede, The Netherlands and Pain Research & Nuffield Department of Anaesthetics, Oxford University, Oxford, UK.

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http://rheumatology.oxfordjournals.org/content/early/2014/08
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http://www.rheumatology.oxfordjournals.org/cgi/doi/10.1093/r
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http://dx.doi.org/10.1093/rheumatology/keu332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301711PMC
February 2015

The reliability of a novel magnetic resonance imaging-based tool for the evaluation of forefoot bursae in patients with rheumatoid arthritis: the FFB score.

Rheumatology (Oxford) 2014 Nov 6;53(11):2014-7. Epub 2014 Jun 6.

Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Faculty of Health Sciences, University of Southampton, Department of Podiatry, Solent NHS Trust, Department of Radiology, University Hospital Southampton NHS Foundation Trust, Southampton, UK, Department of Radiology, Klinikum Augsburg, Augsburg, Germany, Department of Radiology, Boston University, Boston, MA, USA, Faculty of Medicine, University of Southampton, Southampton, Nuffield Department of Orthopaedics and Rheumatology, University of Oxford, Oxford and NIHR-Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.1093/rheumatology/keu232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202022PMC
November 2014

Oral bisphosphonate use and total knee/hip implant survival: validation of results in an external population-based cohort.

Arthritis Rheumatol 2014 Nov;66(11):3233-40

University of Oxford, Oxford, UK, University of Southampton and Southampton General Hospital, Southampton, UK; FIMIM-Parc de Salut Mar, Instituto de Salud Carlos III, IDIAP Jordi Gol Primary Care Research Institute, and Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/art.38789DOI Listing
November 2014

A novel methodological approach for measuring symptomatic change following total joint arthroplasty.

J Arthroplasty 2014 Nov 19;29(11):2140-5. Epub 2014 Jun 19.

NIHR Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; MRC Life course Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1016/j.arth.2014.06.008DOI Listing
November 2014

Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other joints.

Ann Rheum Dis 2014 Sep 6;73(9):1659-64. Epub 2013 Jun 6.

Oxford NIHR Musculoskeletal BRU, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1136/annrheumdis-2013-203355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875433PMC
September 2014

Relationship between mortality and BMI after fracture: a population-based study of men and women aged ≥40 years.

J Bone Miner Res 2014 Aug;29(8):1737-44

Grup de Recerca en Malalties Prevalents de l'Aparell Locomotor (GREMPAL), Informació pel Desenvolupament de la Investigació en Atenció Primària (IDIAP) Jordi Gol Primary Care Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain; Unitat de Recerca en Fisiopatologia Òssia i Articular (URFOA), Institut Municipal d'Investigacions Mèdiques, Parc de Salut Mar, Barcelona, Spain; Oxford National Institute for Health Research (NIHR) Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Primary Care Department, Institut Català de la Salut, Barcelona, Spain; Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), Instituto Carlos III, Barcelona, Spain.

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http://dx.doi.org/10.1002/jbmr.2209DOI Listing
August 2014

A randomized saline-controlled trial of NASHA hyaluronic acid for knee osteoarthritis.

Curr Med Res Opin 2014 Feb 5;30(2):279-86. Epub 2013 Nov 5.

NIHR Musculoskeletal Biomedical Research Unit, University of Oxford , UK.

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http://www.tandfonline.com/doi/full/10.1185/03007995.2013.85
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http://dx.doi.org/10.1185/03007995.2013.855631DOI Listing
February 2014

Decision making in knee arthroplasty.

Rheumatology (Oxford) 2014 Feb 31;53(2):203-4. Epub 2013 Oct 31.

Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK.

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http://dx.doi.org/10.1093/rheumatology/ket339DOI Listing
February 2014

Predictors of fracture while on treatment with oral bisphosphonates: a population-based cohort study.

J Bone Miner Res 2014 Jan;29(1):268-74

Unitat de Recerca en Fisiopatologia Òssia i Articular (URFOA-IMIM) and Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), Parc de Salut Mar, Barcelona, Spain; National Institute for Health Research (NIHR) Biomedical Research Unit, Musculoskeletal Epidemiology Group, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Grup de Recerca en Malalties Prevalents de l'Aparell Locomotor (GREMPAL) Research Group, Institut d'Investigació en Atenció Primària (IDIAP) Jordi Gol Primary Care Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain; Medical Research Council (MRC) Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1002/jbmr.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867340PMC
January 2014

Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.

BMJ 2013 Nov 27;347:f6549. Epub 2013 Nov 27.

National Institute for Health Research Oxford Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Headington, Oxford OX3 7LD, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898581PMC
http://dx.doi.org/10.1136/bmj.f6549DOI Listing
November 2013

Cam impingement of the hip: a risk factor for hip osteoarthritis.

Nat Rev Rheumatol 2013 10 23;9(10):630-4. Epub 2013 Jul 23.

Department of Orthopaedics, Erasmus MC University Medical Centre, Room EE16-18, Dr Molewaterplein 50, 3015 GE, Rotterdam, Netherlands.

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http://dx.doi.org/10.1038/nrrheum.2013.114DOI Listing
October 2013

Lower limbs composition and radiographic knee osteoarthritis (RKOA) in Chingford sample--a longitudinal study.

Arch Gerontol Geriatr 2013 Jan-Feb;56(1):148-54. Epub 2012 Oct 18.

Human Population Biology Research Unit, Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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https://linkinghub.elsevier.com/retrieve/pii/S01674943120020
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http://dx.doi.org/10.1016/j.archger.2012.09.006DOI Listing
May 2013

Mapping the Oxford hip score onto the EQ-5D utility index.

Qual Life Res 2013 Apr 22;22(3):665-75. Epub 2012 Apr 22.

Wessex Institute, University of Southampton, Alpha House, Enterprise Road, Chilworth, Southampton, SO16 7NS, UK.

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http://dx.doi.org/10.1007/s11136-012-0174-yDOI Listing
April 2013

The association of patient characteristics and surgical variables on symptoms of pain and function over 5 years following primary hip-replacement surgery: a prospective cohort study.

BMJ Open 2013 Mar 1;3(3). Epub 2013 Mar 1.

Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Headington, Oxford, UK.

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http://dx.doi.org/10.1136/bmjopen-2012-002453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612787PMC
March 2013

Regional and temporal variation in the treatment of rheumatoid arthritis across the UK: a descriptive register-based cohort study.

BMJ Open 2012 8;2(6). Epub 2012 Nov 8.

Department of Rheumatology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.1136/bmjopen-2012-001603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533005PMC
November 2012

Predictors of outcomes of total knee replacement surgery.

Rheumatology (Oxford) 2012 Oct 24;51(10):1804-13. Epub 2012 Apr 24.

Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Headington, Oxford, UK.

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http://dx.doi.org/10.1093/rheumatology/kes075DOI Listing
October 2012

Clinical tool to identify patients who are most likely to achieve long-term improvement in physical function after total hip arthroplasty.

Arthritis Care Res (Hoboken) 2012 Jun 9;64(6):881-9. Epub 2012 Jan 9.

University of Southampton and Southampton General Hospital, Southampton, and University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/acr.21594DOI Listing
June 2012

Vitamin D threshold to prevent aromatase inhibitor-related bone loss: the B-ABLE prospective cohort study.

Breast Cancer Res Treat 2012 Jun 21;133(3):1159-67. Epub 2012 Mar 21.

URFOA-IMIM, Parc de Salut Mar, Parc de Recerca Biomèdica de Barcelona, C/Dr Aiguader, 88, 2nd Floor, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1007/s10549-012-2013-9DOI Listing
June 2012

How do physicians weigh benefits and risks associated with treatments in patients with osteoarthritis in the United Kingdom?

J Rheumatol 2012 May 15;39(5):1056-63. Epub 2012 Mar 15.

Health Preference Assessment, RTI Health Solutions, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.3899/jrheum.111066DOI Listing
May 2012

Knee replacement.

Lancet 2012 Apr 6;379(9823):1331-40. Epub 2012 Mar 6.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S0140-6736(11)60752-6DOI Listing
April 2012

Knee arthroplasty and risk of hip fracture: a population-based, case-control study.

Calcif Tissue Int 2012 Feb 18;90(2):144-50. Epub 2011 Dec 18.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00223-011-9558-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271227PMC
February 2012

Peripheral neuropathy in ANCA-associated vasculitis: outcomes from the European Vasculitis Study Group trials.

Rheumatology (Oxford) 2011 Dec 2;50(12):2214-22. Epub 2011 Sep 2.

Rheumatology Department, Greenlane Clinical Centre, Epsom, Auckland, New Zealand.

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http://dx.doi.org/10.1093/rheumatology/ker266DOI Listing
December 2011

Association between bisphosphonate use and implant survival after primary total arthroplasty of the knee or hip: population based retrospective cohort study.

BMJ 2011 Dec 6;343:d7222. Epub 2011 Dec 6.

Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232250PMC
http://dx.doi.org/10.1136/bmj.d7222DOI Listing
December 2011