Publications by authors named "Nicoletta Sacchi"

57Publications

Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19.

J Transl Med 2020 09 15;18(1):352. Epub 2020 Sep 15.

Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Via Salvatore Allende, 84081, Baronissi, SA, Italy.

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http://dx.doi.org/10.1186/s12967-020-02515-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491019PMC
September 2020

Emerging Cancer Epigenetic Mechanisms Regulated by All-Trans Retinoic Acid.

Cancers (Basel) 2020 Aug 14;12(8). Epub 2020 Aug 14.

Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.3390/cancers12082275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465226PMC
August 2020

Genomewide Association Study of Severe Covid-19 with Respiratory Failure.

Authors:
David Ellinghaus Frauke Degenhardt Luis Bujanda Maria Buti Agustín Albillos Pietro Invernizzi Javier Fernández Daniele Prati Guido Baselli Rosanna Asselta Marit M Grimsrud Chiara Milani Fátima Aziz Jan Kässens Sandra May Mareike Wendorff Lars Wienbrandt Florian Uellendahl-Werth Tenghao Zheng Xiaoli Yi Raúl de Pablo Adolfo G Chercoles Adriana Palom Alba-Estela Garcia-Fernandez Francisco Rodriguez-Frias Alberto Zanella Alessandra Bandera Alessandro Protti Alessio Aghemo Ana Lleo Andrea Biondi Andrea Caballero-Garralda Andrea Gori Anja Tanck Anna Carreras Nolla Anna Latiano Anna Ludovica Fracanzani Anna Peschuck Antonio Julià Antonio Pesenti Antonio Voza David Jiménez Beatriz Mateos Beatriz Nafria Jimenez Carmen Quereda Cinzia Paccapelo Christoph Gassner Claudio Angelini Cristina Cea Aurora Solier David Pestaña Eduardo Muñiz-Diaz Elena Sandoval Elvezia M Paraboschi Enrique Navas Félix García Sánchez Ferruccio Ceriotti Filippo Martinelli-Boneschi Flora Peyvandi Francesco Blasi Luis Téllez Albert Blanco-Grau Georg Hemmrich-Stanisak Giacomo Grasselli Giorgio Costantino Giulia Cardamone Giuseppe Foti Serena Aneli Hayato Kurihara Hesham ElAbd Ilaria My Iván Galván-Femenia Javier Martín Jeanette Erdmann Jose Ferrusquía-Acosta Koldo Garcia-Etxebarria Laura Izquierdo-Sanchez Laura R Bettini Lauro Sumoy Leonardo Terranova Leticia Moreira Luigi Santoro Luigia Scudeller Francisco Mesonero Luisa Roade Malte C Rühlemann Marco Schaefer Maria Carrabba Mar Riveiro-Barciela Maria E Figuera Basso Maria G Valsecchi María Hernandez-Tejero Marialbert Acosta-Herrera Mariella D'Angiò Marina Baldini Marina Cazzaniga Martin Schulzky Maurizio Cecconi Michael Wittig Michele Ciccarelli Miguel Rodríguez-Gandía Monica Bocciolone Monica Miozzo Nicola Montano Nicole Braun Nicoletta Sacchi Nilda Martínez Onur Özer Orazio Palmieri Paola Faverio Paoletta Preatoni Paolo Bonfanti Paolo Omodei Paolo Tentorio Pedro Castro Pedro M Rodrigues Aaron Blandino Ortiz Rafael de Cid Ricard Ferrer Roberta Gualtierotti Rosa Nieto Siegfried Goerg Salvatore Badalamenti Sara Marsal Giuseppe Matullo Serena Pelusi Simonas Juzenas Stefano Aliberti Valter Monzani Victor Moreno Tanja Wesse Tobias L Lenz Tomas Pumarola Valeria Rimoldi Silvano Bosari Wolfgang Albrecht Wolfgang Peter Manuel Romero-Gómez Mauro D'Amato Stefano Duga Jesus M Banales Johannes R Hov Trine Folseraas Luca Valenti Andre Franke Tom H Karlsen

N Engl J Med 2020 10 17;383(16):1522-1534. Epub 2020 Jun 17.

From the Institute of Clinical Molecular Biology, Christian-Albrechts-University (D.E., F.D., J.K., S. May, M. Wendorff, L.W., F.U.-W., X.Y., A.T., A. Peschuck, C.G., G.H.-S., H.E.A., M.C.R., M.E.F.B., M. Schulzky, M. Wittig, N.B., S.J., T.W., W.A., M. D'Amato, A.F.), and University Hospital Schleswig-Holstein, Campus Kiel (N.B., A.F.), Kiel, the Institute for Cardiogenetics, University of Lübeck, Lübeck (J.E.), the German Research Center for Cardiovascular Research, partner site Hamburg-Lübeck-Kiel (J.E.), the University Heart Center Lübeck (J.E.), and the Institute of Transfusion Medicine, University Hospital Schleswig-Holstein (S.G.), Lübeck, Stefan-Morsch-Stiftung, Birkenfeld (M. Schaefer, W.P.), and the Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön (O.O., T.L.L.) - all in Germany; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (D.E.); the Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital-University of the Basque Country (L.B., K.G.-E., L.I.-S., P.M.R., J.M.B.), Osakidetza Basque Health Service, Donostialdea Integrated Health Organization, Clinical Biochemistry Department (A.G.C., B.N.J.), and the Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute (M. D'Amato), San Sebastian, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, Instituto de Salud Carlos III (L.B., M. Buti, A. Albillos, A. Palom, F.R.-F., B.M., L. Téllez, K.G.-E., L.I.-S., F.M., L.R., M.R.-B., M. Rodríguez-Gandía, P.M.R., M. Romero-Gómez, J.M.B.), the Departments of Gastroenterology (A. Albillos, B.M., L. Téllez, F.M., M. Rodríguez-Gandía), Intensive Care (R.P., A.B.O.), Respiratory Diseases (D.J., A.S., R.N.), Infectious Diseases (C.Q., E.N.), and Anesthesiology (D. Pestaña, N. Martínez), Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, University of Alcalá, and Histocompatibilidad y Biologia Molecular, Centro de Transfusion de Madrid (F.G.S.), Madrid, the Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus (M. Buti, A. Palom, L.R., M.R.-B.), Hospital Clinic, University of Barcelona, and the August Pi i Sunyer Biomedical Research Institute (J.F., F.A., E.S., J.F.-A., L.M., M.H.-T., P.C.), the European Foundation for the Study of Chronic Liver Failure (J.F.), Vall d'Hebron Institut de Recerca (A. Palom, F.R.-F., A.J., S. Marsal), and the Departments of Biochemistry (A.-E.G.-F., F.R.-F., A.C.-G., C.C., A.B.-G.), Intensive Care (R.F.), and Microbiology (T.P.), University Hospital Vall d'Hebron, the Immunohematology Department, Banc de Sang i Teixits, Autonomous University of Barcelona (E.M.-D.), Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Consortium for Biomedical Research in Epidemiology and Public Health and University of Barcelona, l'Hospitalet (V. Moreno), and Autonoma University of Barcelona (T.P.), Barcelona, Universitat Autònoma de Barcelona, Bellatera (M. Buti, F.R.-F., M.R.-B.), GenomesForLife-GCAT Lab Group, Germans Trias i Pujol Research Institute (A.C.N., I.G.-F., R.C.), and High Content Genomics and Bioinformatics Unit, Germans Trias i Pujol Research Institute (L. Sumoy), Badalona, Institute of Parasitology and Biomedicine Lopez-Neyra, Granada (J.M., M.A.-H.), the Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, Seville (M. Romero-Gómez), and Ikerbasque, Basque Foundation for Science, Bilbao (M. D'Amato, J.M.B.) - all in Spain; the Division of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milan Bicocca (P.I., C.M.), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (D. Prati, G.B., A.Z., A. Bandera, A.G., A.L.F., A. Pesenti, C.P., F.C., F.M.-B., F.P., F.B., G.G., G. Costantino, L. Terranova, L. Santoro, L. Scudeller, M. Carrabba, M. Baldini, M.M., N. Montano, R.G., S.P., S. Aliberti, V. Monzani, S. Bosari, L.V.), the Department of Biomedical Sciences, Humanitas University (R.A., A. Protti, A. Aghemo, A. Lleo, E.M.P., G. Cardamone, M. Cecconi, V.R., S.D.), Humanitas Clinical and Research Center, IRCCS (R.A., A. Protti, A. Aghemo, A. Lleo, A.V., C.A., E.M.P., H.K., I.M., M. Cecconi, M. Ciccarelli, M. Bocciolone, P.P., P.O., P.T., S. Badalamenti, S.D.), University of Milan (A.Z., A. Bandera, A.G., A.L.F., A. Pesenti, F.M.-B., F.P., F.B., G.G., G. Costantino, M.M., N. Montano, R.G., S.P., S. Aliberti, S. Bosari, L.V.), and the Center of Bioinformatics, Biostatistics, and Bioimaging (M.G.V.) and the Phase 1 Research Center (M. Cazzaniga), School of Medicine and Surgery, and the Departments of Emergency, Anesthesia, and Intensive Care (G.F.), Pneumologia (P.F.), and Infectious Diseases (P.B.); University of Milano-Bicocca, Milan, the European Reference Network on Hepatological Diseases (P.I., C.M.) and the Infectious Diseases Unit (P.B.), San Gerardo Hospital, Monza, the Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale, San Gerardo (A. Biondi, L.R.B., M. D'Angiò), the Gastroenterology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (A. Latiano, O.P.), the Department of Medical Sciences, Università degli Studi di Torino, Turin (S. Aneli, G.M.), and the Italian Bone Marrow Donor Registry, E.O. Ospedali Galliera, Genoa (N.S.) - all in Italy; the Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases, and Transplantation, and the Research Institute for Internal Medicine, Division of Surgery, Inflammatory Diseases, and Transplantation, Oslo University Hospital Rikshospitalet and University of Oslo (M.M.G., J.R.H., T.F., T.H.K.), and the Section for Gastroenterology, Department of Transplantation Medicine, Division for Cancer Medicine, Surgery, and Transplantation, Oslo University Hospital Rikshospitalet (J.R.H., T.F., T.H.K.), Oslo; the School of Biological Sciences, Monash University, Clayton, VIC, Australia (T.Z., M. D'Amato); Private University in the Principality of Liechtenstein (C.G.); the Institute of Biotechnology, Vilnius University, Vilnius, Lithuania (S.J.); and the Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm (M. D'Amato).

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http://dx.doi.org/10.1056/NEJMoa2020283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315890PMC
October 2020

qPCR Applications for the Determination of the Biological Age.

Methods Mol Biol 2020 ;2065:191-197

Ente Ospedaliero Ospedali Galliera, Genoa, Italy.

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http://dx.doi.org/10.1007/978-1-4939-9833-3_14DOI Listing
January 2020

Quality control project of NGS HLA genotyping for the 17th International HLA and Immunogenetics Workshop.

Hum Immunol 2019 Apr 6;80(4):228-236. Epub 2019 Feb 6.

Histocompatibility, Immunogenetics, and Disease Profiling Laboratory, Stanford Blood Center, Palo Alto, CA, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1016/j.humimm.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446570PMC
April 2019

3D Mammary Epithelial Cell Models: A Goldmine of DCIS Biomarkers and Morphogenetic Mechanisms.

Cancers (Basel) 2019 Jan 23;11(2). Epub 2019 Jan 23.

Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.3390/cancers11020130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407115PMC
January 2019

Undermining ribosomal RNA transcription in both the nucleolus and mitochondrion: an offbeat approach to target MYC-driven cancer.

Oncotarget 2018 Jan 22;9(4):5016-5031. Epub 2017 Dec 22.

Department of Cancer Genetics and Genomics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.18632/oncotarget.23579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797030PMC
January 2018

MiR-221-regulated KIT level by wild type or leukemia mutant RUNX1: a determinant of single myeloblast fate decisions that - collectively - drives or hinders granulopoiesis.

Oncotarget 2017 Oct 23;8(49):85783-85793. Epub 2017 Sep 23.

Department of Cancer Genetics and Genomics, Roswell Park Cancer Institute, Buffalo, NY 14263.

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http://dx.doi.org/10.18632/oncotarget.21266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689646PMC
October 2017

Is it time to re-think a sustainable banking model for the Italian Cord Blood Network?

Authors:
Nicoletta Sacchi

Blood Transfus 2018 05 13;16(3):221-223. Epub 2017 Apr 13.

Italian Bone Marrow Donor Registry, Galliera Hospital, Genoa, Italy.

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http://dx.doi.org/10.2450/2017.0040-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919832PMC
May 2018

Mammary epithelial morphogenesis and early breast cancer. Evidence of involvement of basal components of the RNA Polymerase I transcription machinery.

Cell Cycle 2016 Sep 2;15(18):2515-26. Epub 2016 Aug 2.

a Department of Cancer Genetics , Roswell Park Cancer Institute , Buffalo , NY , USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026817PMC
http://dx.doi.org/10.1080/15384101.2016.1215385DOI Listing
September 2016

RUNX1: A microRNA hub in normal and malignant hematopoiesis.

Int J Mol Sci 2013 Jan 14;14(1):1566-88. Epub 2013 Jan 14.

Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.3390/ijms14011566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565335PMC
January 2013

Identification of an estrogen-regulated circadian mechanism necessary for breast acinar morphogenesis.

Cell Cycle 2012 Oct 30;11(19):3691-700. Epub 2012 Aug 30.

Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY, USA.

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http://dx.doi.org/10.4161/cc.21946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478319PMC
October 2012

Loss of MTG16a (CBFA2T3), a novel rDNA repressor, leads to increased ribogenesis and disruption of breast acinar morphogenesis.

J Cell Mol Med 2010 Jun 2;14(6A):1358-70. Epub 2009 Dec 2.

Cancer Genetics Program, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1111/j.1582-4934.2009.00982.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828852PMC
June 2010

Novel RNA-binding properties of the MTG chromatin regulatory proteins.

BMC Mol Biol 2008 Oct 24;9:93. Epub 2008 Oct 24.

Cancer Genetics Program, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1186/1471-2199-9-93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579434PMC
October 2008

Disruption of retinoic acid receptor alpha reveals the growth promoter face of retinoic acid.

PLoS One 2007 Sep 5;2(9):e836. Epub 2007 Sep 5.

Cancer Genetics Program, Department of Cancer Biology, Roswell Park Cancer Institute, Buffalo, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000836PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959242PMC
September 2007

The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on.

Nat Protoc 2006 ;1(2):581-5

Molecular Research Center, 2600 Clifton Avenue, Cincinnati, Ohio 45221, USA.

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http://dx.doi.org/10.1038/nprot.2006.83DOI Listing
September 2007

A distinct epigenetic signature at targets of a leukemia protein.

BMC Genomics 2007 Feb 1;8:38. Epub 2007 Feb 1.

Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1186/1471-2164-8-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796549PMC
February 2007

A repressive epigenetic domino effect confers susceptibility to breast epithelial cell transformation: implications for predicting breast cancer risk.

Cancer Res 2006 Nov;66(21):10308-14

Department of Cancer Genetics, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, New York 14263, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1052DOI Listing
November 2006

Resveratrol impairs the formation of MDA-MB-231 multicellular tumor spheroids concomitant with ceramide accumulation.

Cancer Lett 2007 May 22;249(2):143-7. Epub 2006 Sep 22.

Department of Biology and Genetics for Health Sciences, University of Milan, Italy.

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http://dx.doi.org/10.1016/j.canlet.2006.08.013DOI Listing
May 2007

Impaired retinoic acid (RA) signal leads to RARbeta2 epigenetic silencing and RA resistance.

Mol Cell Biol 2005 Dec;25(23):10591-603

Roswell Park Cancer Institute, Elm & Carlton Streets, C&V Bldg., RM 226, Buffalo, NY 14263.

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http://dx.doi.org/10.1128/MCB.25.23.10591-10603.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291229PMC
December 2005

Myeloid maturation block by AML1-MTG16 is associated with Csf1r epigenetic downregulation.

Oncogene 2005 Aug;24(34):5325-32

Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1038/sj.onc.1208651DOI Listing
August 2005

Sasa health exerts a protective effect on Her2/NeuN mammary tumorigenesis.

Anticancer Res 2004 Sep-Oct;24(5A):2879-84

Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

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December 2004

The MTG proteins: chromatin repression players with a passion for networking.

Genomics 2004 Jul;84(1):1-9

Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1016/j.ygeno.2004.02.011DOI Listing
July 2004

Very high frequency of hypermethylated genes in breast cancer metastasis to the bone, brain, and lung.

Clin Cancer Res 2004 May;10(9):3104-9

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1158/1078-0432.ccr-03-0118DOI Listing
May 2004

Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling.

FASEB J 2003 Dec 16;17(15):2339-41. Epub 2003 Oct 16.

Laboratory of Biochemistry and Molecular Biology, San Paolo University Hospital, School of Medicine, University of Milan, 20142 Milan, Italy.

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http://dx.doi.org/10.1096/fj.03-0292fjeDOI Listing
December 2003

Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer.

Cancer Res 2002 May;62(9):2455-61

Laboratory of Genetics and Biochemistry, San Paolo University Hospital, School of Medicine, University of Milan, 20142 Milan, Italy.

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May 2002