Publications by authors named "Nicole M Warrington"

69Publications

The Effect of Plasma Lipids and Lipid-Lowering Interventions on Bone Mineral Density: A Mendelian Randomization Study.

J Bone Miner Res 2020 Jul 12;35(7):1224-1235. Epub 2020 Mar 12.

Medical Research Council (MRC) Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1002/jbmr.3989DOI Listing
July 2020

Integrating Family-Based and Mendelian Randomization Designs.

Cold Spring Harb Perspect Med 2020 Mar 2. Epub 2020 Mar 2.

The University of Queensland Diamantina Institute, University of Queensland, Brisbane, Queensland 4102, Australia.

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http://dx.doi.org/10.1101/cshperspect.a039503DOI Listing
March 2020

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI.

Sci Adv 2019 09 4;5(9):eaaw3095. Epub 2019 Sep 4.

Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.

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http://dx.doi.org/10.1126/sciadv.aaw3095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904961PMC
September 2019

Introducing M-GCTA a Software Package to Estimate Maternal (or Paternal) Genetic Effects on Offspring Phenotypes.

Behav Genet 2020 01 6;50(1):51-66. Epub 2019 Sep 6.

University of Queensland Diamantina Institute, University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1007/s10519-019-09969-4DOI Listing
January 2020

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization.

Int J Epidemiol 2019 06;48(3):861-875

University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1093/ije/dyz019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659380PMC
June 2019

Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies.

Behav Genet 2019 05 2;49(3):327-339. Epub 2019 Jan 2.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1007/s10519-018-9944-9DOI Listing
May 2019

Antibody response to common human viruses is shaped by genetic factors.

J Allergy Clin Immunol 2019 04 20;143(4):1640-1643. Epub 2018 Dec 20.

University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia; QIMR Berghofer Medical Research Institute, Brisbane, Australia; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.11.039DOI Listing
April 2019

Altered hemodynamics contribute to local but not remote functional connectivity disruption due to glioma growth.

J Cereb Blood Flow Metab 2020 01 18;40(1):100-115. Epub 2018 Oct 18.

Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.

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http://dx.doi.org/10.1177/0271678X18803948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928560PMC
January 2020

Cooperative p16 and p21 action protects female astrocytes from transformation.

Acta Neuropathol Commun 2018 02 20;6(1):12. Epub 2018 Feb 20.

Department of Pediatrics, Washington University School of Medicine, Campus Box 8208, 660 South Euclid Ave, St Louis, MO, 63110, USA.

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http://dx.doi.org/10.1186/s40478-018-0513-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819173PMC
February 2018

Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK Biobank.

Int J Epidemiol 2018 08;47(4):1229-1241

University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1093/ije/dyy015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124616PMC
August 2018

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics.

Hum Mol Genet 2018 02;27(4):742-756

Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK.

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http://dx.doi.org/10.1093/hmg/ddx429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886200PMC
February 2018

Reprogramming Medulloblastoma-Propagating Cells by a Combined Antagonism of Sonic Hedgehog and CXCR4.

Cancer Res 2017 03 28;77(6):1416-1426. Epub 2016 Dec 28.

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505622PMC
March 2017

Genome-wide associations for birth weight and correlations with adult disease.

Authors:
Momoko Horikoshi Robin N Beaumont Felix R Day Nicole M Warrington Marjolein N Kooijman Juan Fernandez-Tajes Bjarke Feenstra Natalie R van Zuydam Kyle J Gaulton Niels Grarup Jonathan P Bradfield David P Strachan Ruifang Li-Gao Tarunveer S Ahluwalia Eskil Kreiner Rico Rueedi Leo-Pekka Lyytikäinen Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Jouke-Jan Hottenga Natalia Vilor-Tejedor Peter K Joshi Eileen Tai Hui Boh Ioanna Ntalla Niina Pitkänen Anubha Mahajan Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Michael Nodzenski Louise A Diver Krina T Zondervan Mariona Bustamante Pedro Marques-Vidal Josep M Mercader Amanda J Bennett Nilufer Rahmioglu Dale R Nyholt Ronald Ching Wan Ma Claudia Ha Ting Tam Wing Hung Tam Santhi K Ganesh Frank Ja van Rooij Samuel E Jones Po-Ru Loh Katherine S Ruth Marcus A Tuke Jessica Tyrrell Andrew R Wood Hanieh Yaghootkar Denise M Scholtens Lavinia Paternoster Inga Prokopenko Peter Kovacs Mustafa Atalay Sara M Willems Kalliope Panoutsopoulou Xu Wang Lisbeth Carstensen Frank Geller Katharina E Schraut Mario Murcia Catharina Em van Beijsterveldt Gonneke Willemsen Emil V R Appel Cilius E Fonvig Caecilie Trier Carla Mt Tiesler Marie Standl Zoltán Kutalik Sílvia Bonas-Guarch David M Hougaard Friman Sánchez David Torrents Johannes Waage Mads V Hollegaard Hugoline G de Haan Frits R Rosendaal Carolina Medina-Gomez Susan M Ring Gibran Hemani George McMahon Neil R Robertson Christopher J Groves Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Frank D Mentch Scott M MacKenzie Rebecca M Reynolds William L Lowe Anke Tönjes Michael Stumvoll Virpi Lindi Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Thorkild Ia Sørensen Harri Niinikoski Katja Pahkala Olli T Raitakari Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Mads Melbye Harry Campbell James F Wilson Martine Vrijheid Eco Jcn de Geus Dorret I Boomsma Haja N Kadarmideen Jens-Christian Holm Torben Hansen Sylvain Sebert Andrew T Hattersley Lawrence J Beilin John P Newnham Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Mika Kähönen Jorma S Viikari Terho Lehtimäki Peter Vollenweider Klaus Bønnelykke Hans Bisgaard Dennis O Mook-Kanamori Albert Hofman Fernando Rivadeneira André G Uitterlinden Charlotta Pisinger Oluf Pedersen Christine Power Elina Hyppönen Nicholas J Wareham Hakon Hakonarson Eleanor Davies Brian R Walker Vincent Wv Jaddoe Marjo-Riitta Jarvelin Struan Fa Grant Allan A Vaag Debbie A Lawlor Timothy M Frayling George Davey Smith Andrew P Morris Ken K Ong Janine F Felix Nicholas J Timpson John Rb Perry David M Evans Mark I McCarthy Rachel M Freathy

Nature 2016 10 28;538(7624):248-252. Epub 2016 Sep 28.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/nature19806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164934PMC
October 2016

Targeting brain tumor cAMP: the case for sex-specific therapeutics.

Front Pharmacol 2015 28;6:153. Epub 2015 Jul 28.

Department of Pediatrics, Washington University School of Medicine St Louis, MO, USA ; Department of Anatomy and Neurobiology, Washington University School of Medicine St Louis, MO, USA.

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http://dx.doi.org/10.3389/fphar.2015.00153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516881PMC
August 2015

A genome-wide association study of body mass index across early life and childhood.

Int J Epidemiol 2015 Apr 7;44(2):700-12. Epub 2015 May 7.

School of Women's and Infants' Health, University of Western Australia, Perth, WA, Australia, University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia, MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK, School of Social and Community Medicine, University of Bristol, Bristol, UK, Biocenter Oulu, and Institute of Health Sciences, University of Oulu, Oulu, Finland, Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, UK, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada, Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland, Department of Epidemiology and Biostatistics, MRC-HPA Centre for Environment and Health, School of Public Health, Imperial College London, London, UK, Unit of Primary Care, Oulu University Hospital, Oulu, Finland and The Joanna Briggs Institute, The Robinson Research Institute, and School of Translational Health Science, University of Adelaide, Adelaide, SA, Australia.

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http://dx.doi.org/10.1093/ije/dyv077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469798PMC
April 2015

Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescence.

Hum Mol Genet 2015 Jul 4;24(14):4158-66. Epub 2015 May 4.

The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, Australia, MRC Integrative Epidemiology Unit, School of Social and Community Medicine and

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http://dx.doi.org/10.1093/hmg/ddv143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476449PMC
July 2015

A novel common variant in DCST2 is associated with length in early life and height in adulthood.

Authors:
Ralf J P van der Valk Eskil Kreiner-Møller Marjolein N Kooijman Mònica Guxens Evangelia Stergiakouli Annika Sääf Jonathan P Bradfield Frank Geller M Geoffrey Hayes Diana L Cousminer Antje Körner Elisabeth Thiering John A Curtin Ronny Myhre Ville Huikari Raimo Joro Marjan Kerkhof Nicole M Warrington Niina Pitkänen Ioanna Ntalla Momoko Horikoshi Riitta Veijola Rachel M Freathy Yik-Ying Teo Sheila J Barton David M Evans John P Kemp Beate St Pourcain Susan M Ring George Davey Smith Anna Bergström Inger Kull Hakon Hakonarson Frank D Mentch Hans Bisgaard Bo Chawes Jakob Stokholm Johannes Waage Patrick Eriksen Astrid Sevelsted Mads Melbye Cornelia M van Duijn Carolina Medina-Gomez Albert Hofman Johan C de Jongste H Rob Taal André G Uitterlinden Loren L Armstrong Johan Eriksson Aarno Palotie Mariona Bustamante Xavier Estivill Juan R Gonzalez Sabrina Llop Wieland Kiess Anubha Mahajan Claudia Flexeder Carla M T Tiesler Clare S Murray Angela Simpson Per Magnus Verena Sengpiel Anna-Liisa Hartikainen Sirkka Keinanen-Kiukaanniemi Alexandra Lewin Alexessander Da Silva Couto Alves Alexandra I Blakemore Jessica L Buxton Marika Kaakinen Alina Rodriguez Sylvain Sebert Marja Vaarasmaki Timo Lakka Virpi Lindi Ulrike Gehring Dirkje S Postma Wei Ang John P Newnham Leo-Pekka Lyytikäinen Katja Pahkala Olli T Raitakari Kalliope Panoutsopoulou Eleftheria Zeggini Dorret I Boomsma Maria Groen-Blokhuis Jorma Ilonen Lude Franke Joel N Hirschhorn Tune H Pers Liming Liang Jinyan Huang Berthold Hocher Mikael Knip Seang-Mei Saw John W Holloway Erik Melén Struan F A Grant Bjarke Feenstra William L Lowe Elisabeth Widén Elena Sergeyev Harald Grallert Adnan Custovic Bo Jacobsson Marjo-Riitta Jarvelin Mustafa Atalay Gerard H Koppelman Craig E Pennell Harri Niinikoski George V Dedoussis Mark I Mccarthy Timothy M Frayling Jordi Sunyer Nicholas J Timpson Fernando Rivadeneira Klaus Bønnelykke Vincent W V Jaddoe

Hum Mol Genet 2015 Feb 3;24(4):1155-68. Epub 2014 Oct 3.

Department of Epidemiology, Department of Paediatrics, The Generation R Study Group,

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http://hmg.oxfordjournals.org/content/early/2014/10/03/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu510
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http://dx.doi.org/10.1093/hmg/ddu510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447786PMC
February 2015

PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells.

PLoS One 2014 9;9(9):e107397. Epub 2014 Sep 9.

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107397PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159344PMC
May 2015

Association of a body mass index genetic risk score with growth throughout childhood and adolescence.

PLoS One 2013 11;8(11):e79547. Epub 2013 Nov 11.

School of Women's and Infants' Health, The University of Western Australia, Perth, Western Australia, Australia ; Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079547PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823612PMC
November 2014

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.

Am J Epidemiol 2013 Aug 4;178(3):451-60. Epub 2013 Apr 4.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, 137 East Franklin Street, Suite 306, Campus Box 8050, Chapel Hill, NC 27514-8050, USA.

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http://dx.doi.org/10.1093/aje/kws473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816344PMC
August 2013

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.

Hum Mol Genet 2013 Jul 27;22(13):2735-47. Epub 2013 Feb 27.

Institute for Molecular Medicine, and Department of Public Health, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1093/hmg/ddt104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674797PMC
July 2013

Modelling BMI trajectories in children for genetic association studies.

PLoS One 2013 17;8(1):e53897. Epub 2013 Jan 17.

School of Women's and Infants' Health, The University of Western Australia, Perth, Western Australia, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053897PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547961PMC
July 2013

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.

Authors:
Momoko Horikoshi Hanieh Yaghootkar Dennis O Mook-Kanamori Ulla Sovio H Rob Taal Branwen J Hennig Jonathan P Bradfield Beate St Pourcain David M Evans Pimphen Charoen Marika Kaakinen Diana L Cousminer Terho Lehtimäki Eskil Kreiner-Møller Nicole M Warrington Mariona Bustamante Bjarke Feenstra Diane J Berry Elisabeth Thiering Thiemo Pfab Sheila J Barton Beverley M Shields Marjan Kerkhof Elisabeth M van Leeuwen Anthony J Fulford Zoltán Kutalik Jing Hua Zhao Marcel den Hoed Anubha Mahajan Virpi Lindi Liang-Kee Goh Jouke-Jan Hottenga Ying Wu Olli T Raitakari Marie N Harder Aline Meirhaeghe Ioanna Ntalla Rany M Salem Karen A Jameson Kaixin Zhou Dorota M Monies Vasiliki Lagou Mirna Kirin Jani Heikkinen Linda S Adair Fowzan S Alkuraya Ali Al-Odaib Philippe Amouyel Ehm Astrid Andersson Amanda J Bennett Alexandra I F Blakemore Jessica L Buxton Jean Dallongeville Shikta Das Eco J C de Geus Xavier Estivill Claudia Flexeder Philippe Froguel Frank Geller Keith M Godfrey Frédéric Gottrand Christopher J Groves Torben Hansen Joel N Hirschhorn Albert Hofman Mads V Hollegaard David M Hougaard Elina Hyppönen Hazel M Inskip Aaron Isaacs Torben Jørgensen Christina Kanaka-Gantenbein John P Kemp Wieland Kiess Tuomas O Kilpeläinen Norman Klopp Bridget A Knight Christopher W Kuzawa George McMahon John P Newnham Harri Niinikoski Ben A Oostra Louise Pedersen Dirkje S Postma Susan M Ring Fernando Rivadeneira Neil R Robertson Sylvain Sebert Olli Simell Torsten Slowinski Carla M T Tiesler Anke Tönjes Allan Vaag Jorma S Viikari Jacqueline M Vink Nadja Hawwa Vissing Nicholas J Wareham Gonneke Willemsen Daniel R Witte Haitao Zhang Jianhua Zhao James F Wilson Michael Stumvoll Andrew M Prentice Brian F Meyer Ewan R Pearson Colin A G Boreham Cyrus Cooper Matthew W Gillman George V Dedoussis Luis A Moreno Oluf Pedersen Maiju Saarinen Karen L Mohlke Dorret I Boomsma Seang-Mei Saw Timo A Lakka Antje Körner Ruth J F Loos Ken K Ong Peter Vollenweider Cornelia M van Duijn Gerard H Koppelman Andrew T Hattersley John W Holloway Berthold Hocher Joachim Heinrich Chris Power Mads Melbye Mònica Guxens Craig E Pennell Klaus Bønnelykke Hans Bisgaard Johan G Eriksson Elisabeth Widén Hakon Hakonarson André G Uitterlinden Anneli Pouta Debbie A Lawlor George Davey Smith Timothy M Frayling Mark I McCarthy Struan F A Grant Vincent W V Jaddoe Marjo-Riitta Jarvelin Nicholas J Timpson Inga Prokopenko Rachel M Freathy

Nat Genet 2013 Jan 2;45(1):76-82. Epub 2012 Dec 2.

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.2477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605762PMC
January 2013

Genome-wide meta-analysis of common variant differences between men and women.

Authors:
Vesna Boraska Ana Jerončić Vincenza Colonna Lorraine Southam Dale R Nyholt Nigel William Rayner John R B Perry Daniela Toniolo Eva Albrecht Wei Ang Stefania Bandinelli Maja Barbalic Inês Barroso Jacques S Beckmann Reiner Biffar Dorret Boomsma Harry Campbell Tanguy Corre Jeanette Erdmann Tõnu Esko Krista Fischer Nora Franceschini Timothy M Frayling Giorgia Girotto Juan R Gonzalez Tamara B Harris Andrew C Heath Iris M Heid Wolfgang Hoffmann Albert Hofman Momoko Horikoshi Jing Hua Zhao Anne U Jackson Jouke-Jan Hottenga Antti Jula Mika Kähönen Kay-Tee Khaw Lambertus A Kiemeney Norman Klopp Zoltán Kutalik Vasiliki Lagou Lenore J Launer Terho Lehtimäki Mathieu Lemire Marja-Liisa Lokki Christina Loley Jian'an Luan Massimo Mangino Irene Mateo Leach Sarah E Medland Evelin Mihailov Grant W Montgomery Gerjan Navis John Newnham Markku S Nieminen Aarno Palotie Kalliope Panoutsopoulou Annette Peters Nicola Pirastu Ozren Polasek Karola Rehnström Samuli Ripatti Graham R S Ritchie Fernando Rivadeneira Antonietta Robino Nilesh J Samani So-Youn Shin Juha Sinisalo Johannes H Smit Nicole Soranzo Lisette Stolk Dorine W Swinkels Toshiko Tanaka Alexander Teumer Anke Tönjes Michela Traglia Jaakko Tuomilehto Armand Valsesia Wiek H van Gilst Joyce B J van Meurs Albert Vernon Smith Jorma Viikari Jacqueline M Vink Gerard Waeber Nicole M Warrington Elisabeth Widen Gonneke Willemsen Alan F Wright Brent W Zanke Lina Zgaga Michael Boehnke Adamo Pio d'Adamo Eco de Geus Ellen W Demerath Martin den Heijer Johan G Eriksson Luigi Ferrucci Christian Gieger Vilmundur Gudnason Caroline Hayward Christian Hengstenberg Thomas J Hudson Marjo-Riitta Järvelin Manolis Kogevinas Ruth J F Loos Nicholas G Martin Andres Metspalu Craig E Pennell Brenda W Penninx Markus Perola Olli Raitakari Veikko Salomaa Stefan Schreiber Heribert Schunkert Tim D Spector Michael Stumvoll André G Uitterlinden Sheila Ulivi Pim van der Harst Peter Vollenweider Henry Völzke Nicholas J Wareham H-Erich Wichmann James F Wilson Igor Rudan Yali Xue Eleftheria Zeggini

Hum Mol Genet 2012 Nov 27;21(21):4805-15. Epub 2012 Jul 27.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/dds304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471397PMC
November 2012

Common variants at 12q15 and 12q24 are associated with infant head circumference.

Nat Genet 2012 Apr 15;44(5):532-538. Epub 2012 Apr 15.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.2238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773913PMC
April 2012

A genome-wide association meta-analysis identifies new childhood obesity loci.

Nat Genet 2012 May;44(5):526-31

Center for Applied Genomics, Abramson Research Center, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.2247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370100PMC
May 2012

Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts.

PLoS One 2012 29;7(3):e31369. Epub 2012 Mar 29.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031369PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315559PMC
August 2012

Associations between anxious-depressed symptoms and cardiovascular risk factors in a longitudinal childhood study.

Prev Med 2012 May 16;54(5):345-50. Epub 2012 Mar 16.

Centre for Genetic Epidemiology and Biostatistics, the University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1016/j.ypmed.2012.03.004DOI Listing
May 2012

Why does Jack, and not Jill, break his crown? Sex disparity in brain tumors.

Biol Sex Differ 2012 Jan 25;3. Epub 2012 Jan 25.

Department of Pediatrics, Division of Pediatric Hematology-Oncology, Washington University School of Medicine, CB 8208, 660 South Euclid Ave, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1186/2042-6410-3-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293746PMC
January 2012

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Chih-Mei Chen Adaikalavan Ramasamy Klaus Bønnelykke Liesbeth Duijts Manuel A Ferreira Alexessander Couto Alves Jacob P Thyssen Eva Albrecht Hansjörg Baurecht Bjarke Feenstra Patrick M A Sleiman Pirro Hysi Nicole M Warrington Ivan Curjuric Ronny Myhre John A Curtin Maria M Groen-Blokhuis Marjan Kerkhof Annika Sääf Andre Franke David Ellinghaus Regina Fölster-Holst Emmanouil Dermitzakis Stephen B Montgomery Holger Prokisch Katharina Heim Anna-Liisa Hartikainen Anneli Pouta Juha Pekkanen Alexandra I F Blakemore Jessica L Buxton Marika Kaakinen David L Duffy Pamela A Madden Andrew C Heath Grant W Montgomery Philip J Thompson Melanie C Matheson Peter Le Souëf Beate St Pourcain George Davey Smith John Henderson John P Kemp Nicholas J Timpson Panos Deloukas Susan M Ring H-Erich Wichmann Martina Müller-Nurasyid Natalija Novak Norman Klopp Elke Rodríguez Wendy McArdle Allan Linneberg Torkil Menné Ellen A Nohr Albert Hofman André G Uitterlinden Cornélia M van Duijn Fernando Rivadeneira Johan C de Jongste Ralf J P van der Valk Matthias Wjst Rain Jogi Frank Geller Heather A Boyd Jeffrey C Murray Cecilia Kim Frank Mentch Michael March Massimo Mangino Tim D Spector Veronique Bataille Craig E Pennell Patrick G Holt Peter Sly Carla M T Tiesler Elisabeth Thiering Thomas Illig Medea Imboden Wenche Nystad Angela Simpson Jouke-Jan Hottenga Dirkje Postma Gerard H Koppelman Henriette A Smit Cilla Söderhäll Bo Chawes Eskil Kreiner-Møller Hans Bisgaard Erik Melén Dorret I Boomsma Adnan Custovic Bo Jacobsson Nicole M Probst-Hensch Lyle J Palmer Daniel Glass Hakon Hakonarson Mads Melbye Deborah L Jarvis Vincent W V Jaddoe Christian Gieger David P Strachan Nicholas G Martin Marjo-Riitta Jarvelin Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2011 Dec 25;44(2):187-92. Epub 2011 Dec 25.

Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/ng.1017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272375PMC
December 2011

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Authors:
María Soler Artigas Daan W Loth Louise V Wain Sina A Gharib Ma'en Obeidat Wenbo Tang Guangju Zhai Jing Hua Zhao Albert Vernon Smith Jennifer E Huffman Eva Albrecht Catherine M Jackson David M Evans Gemma Cadby Myriam Fornage Ani Manichaikul Lorna M Lopez Toby Johnson Melinda C Aldrich Thor Aspelund Inês Barroso Harry Campbell Patricia A Cassano David J Couper Gudny Eiriksdottir Nora Franceschini Melissa Garcia Christian Gieger Gauti Kjartan Gislason Ivica Grkovic Christopher J Hammond Dana B Hancock Tamara B Harris Adaikalavan Ramasamy Susan R Heckbert Markku Heliövaara Georg Homuth Pirro G Hysi Alan L James Stipan Jankovic Bonnie R Joubert Stefan Karrasch Norman Klopp Beate Koch Stephen B Kritchevsky Lenore J Launer Yongmei Liu Laura R Loehr Kurt Lohman Ruth J F Loos Thomas Lumley Khalid A Al Balushi Wei Q Ang R Graham Barr John Beilby John D Blakey Mladen Boban Vesna Boraska Jonas Brisman John R Britton Guy G Brusselle Cyrus Cooper Ivan Curjuric Santosh Dahgam Ian J Deary Shah Ebrahim Mark Eijgelsheim Clyde Francks Darya Gaysina Raquel Granell Xiangjun Gu John L Hankinson Rebecca Hardy Sarah E Harris John Henderson Amanda Henry Aroon D Hingorani Albert Hofman Patrick G Holt Jennie Hui Michael L Hunter Medea Imboden Karen A Jameson Shona M Kerr Ivana Kolcic Florian Kronenberg Jason Z Liu Jonathan Marchini Tricia McKeever Andrew D Morris Anna-Carin Olin David J Porteous Dirkje S Postma Stephen S Rich Susan M Ring Fernando Rivadeneira Thierry Rochat Avan Aihie Sayer Ian Sayers Peter D Sly George Davey Smith Akshay Sood John M Starr André G Uitterlinden Judith M Vonk S Goya Wannamethee Peter H Whincup Cisca Wijmenga O Dale Williams Andrew Wong Massimo Mangino Kristin D Marciante Wendy L McArdle Bernd Meibohm Alanna C Morrison Kari E North Ernst Omenaas Lyle J Palmer Kirsi H Pietiläinen Isabelle Pin Ozren Pola Sbreve Ek Anneli Pouta Bruce M Psaty Anna-Liisa Hartikainen Taina Rantanen Samuli Ripatti Jerome I Rotter Igor Rudan Alicja R Rudnicka Holger Schulz So-Youn Shin Tim D Spector Ida Surakka Veronique Vitart Henry Völzke Nicholas J Wareham Nicole M Warrington H-Erich Wichmann Sarah H Wild Jemma B Wilk Matthias Wjst Alan F Wright Lina Zgaga Tatijana Zemunik Craig E Pennell Fredrik Nyberg Diana Kuh John W Holloway H Marike Boezen Debbie A Lawlor Richard W Morris Nicole Probst-Hensch Jaakko Kaprio James F Wilson Caroline Hayward Mika Kähönen Joachim Heinrich Arthur W Musk Deborah L Jarvis Sven Gläser Marjo-Riitta Järvelin Bruno H Ch Stricker Paul Elliott George T O'Connor David P Strachan Stephanie J London Ian P Hall Vilmundur Gudnason Martin D Tobin

Nat Genet 2011 Sep 25;43(11):1082-90. Epub 2011 Sep 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267376PMC
September 2011

Treating brain tumors with PDE4 inhibitors.

Trends Pharmacol Sci 2011 Jun 28;32(6):337-44. Epub 2011 Mar 28.

Department of Pediatrics, Campus Box 8208, 660 South Euclid Ave, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.tips.2011.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106141PMC
June 2011

Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth characteristics in different trimesters.

J Clin Endocrinol Metab 2011 May 9;96(5):E810-5. Epub 2011 Feb 9.

The Generation R Study Group and Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2010-2316DOI Listing
May 2011

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

Authors:
Cathy E Elks John R B Perry Patrick Sulem Daniel I Chasman Nora Franceschini Chunyan He Kathryn L Lunetta Jenny A Visser Enda M Byrne Diana L Cousminer Daniel F Gudbjartsson Tõnu Esko Bjarke Feenstra Jouke-Jan Hottenga Daniel L Koller Zoltán Kutalik Peng Lin Massimo Mangino Mara Marongiu Patrick F McArdle Albert V Smith Lisette Stolk Sophie H van Wingerden Jing Hua Zhao Eva Albrecht Tanguy Corre Erik Ingelsson Caroline Hayward Patrik K E Magnusson Erin N Smith Shelia Ulivi Nicole M Warrington Lina Zgaga Helen Alavere Najaf Amin Thor Aspelund Stefania Bandinelli Inês Barroso Gerald S Berenson Sven Bergmann Hannah Blackburn Eric Boerwinkle Julie E Buring Fabio Busonero Harry Campbell Stephen J Chanock Wei Chen Marilyn C Cornelis David Couper Andrea D Coviello Pio d'Adamo Ulf de Faire Eco J C de Geus Panos Deloukas Angela Döring George Davey Smith Douglas F Easton Gudny Eiriksdottir Valur Emilsson Johan Eriksson Luigi Ferrucci Aaron R Folsom Tatiana Foroud Melissa Garcia Paolo Gasparini Frank Geller Christian Gieger Vilmundur Gudnason Per Hall Susan E Hankinson Liana Ferreli Andrew C Heath Dena G Hernandez Albert Hofman Frank B Hu Thomas Illig Marjo-Riitta Järvelin Andrew D Johnson David Karasik Kay-Tee Khaw Douglas P Kiel Tuomas O Kilpeläinen Ivana Kolcic Peter Kraft Lenore J Launer Joop S E Laven Shengxu Li Jianjun Liu Daniel Levy Nicholas G Martin Wendy L McArdle Mads Melbye Vincent Mooser Jeffrey C Murray Sarah S Murray Michael A Nalls Pau Navarro Mari Nelis Andrew R Ness Kate Northstone Ben A Oostra Munro Peacock Lyle J Palmer Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Leena Peltonen Craig E Pennell Paul Pharoah Ozren Polasek Andrew S Plump Anneli Pouta Eleonora Porcu Thorunn Rafnar John P Rice Susan M Ring Fernando Rivadeneira Igor Rudan Cinzia Sala Veikko Salomaa Serena Sanna David Schlessinger Nicholas J Schork Angelo Scuteri Ayellet V Segrè Alan R Shuldiner Nicole Soranzo Ulla Sovio Sathanur R Srinivasan David P Strachan Mar-Liis Tammesoo Emmi Tikkanen Daniela Toniolo Kim Tsui Laufey Tryggvadottir Jonathon Tyrer Manuela Uda Rob M van Dam Joyce B J van Meurs Peter Vollenweider Gerard Waeber Nicholas J Wareham Dawn M Waterworth Michael N Weedon H Erich Wichmann Gonneke Willemsen James F Wilson Alan F Wright Lauren Young Guangju Zhai Wei Vivian Zhuang Laura J Bierut Dorret I Boomsma Heather A Boyd Laura Crisponi Ellen W Demerath Cornelia M van Duijn Michael J Econs Tamara B Harris David J Hunter Ruth J F Loos Andres Metspalu Grant W Montgomery Paul M Ridker Tim D Spector Elizabeth A Streeten Kari Stefansson Unnur Thorsteinsdottir André G Uitterlinden Elisabeth Widen Joanne M Murabito Ken K Ong Anna Murray

Nat Genet 2010 Dec;42(12):1077-85

Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140055PMC
December 2010

The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI.

BMC Med Genet 2010 Oct 8;11:140. Epub 2010 Oct 8.

Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, WA, Australia.

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http://dx.doi.org/10.1186/1471-2350-11-140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958899PMC
October 2010

Characterization of tumor necrosis factor-α block haplotypes associated with susceptibility to chronic venous leg ulcers in Caucasian patients.

Hum Immunol 2010 Dec 18;71(12):1214-9. Epub 2010 Sep 18.

School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S01988859100049
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http://dx.doi.org/10.1016/j.humimm.2010.09.001DOI Listing
December 2010

Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1.

Cancer Res 2010 Jul 15;70(14):5717-27. Epub 2010 Jun 15.

Department of Pediatrics, Molecular Imaging Center, Mallinckrodt Institute of Radiology, Developmental Biology, and Anatomy and Neurobiology, Washington University School of Medicine and St Louis Children's Hospital, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905483PMC
July 2010

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.

Nat Genet 2010 May 6;42(5):430-5. Epub 2010 Apr 6.

Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.

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http://dx.doi.org/10.1038/ng.567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862164PMC
May 2010

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.

Nat Genet 2009 Mar 8;41(3):342-7. Epub 2009 Feb 8.

deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.323DOI Listing
March 2009

Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.

Clin Cancer Res 2008 Dec;14(23):7717-25

Department of Pediatrics, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-0827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615415PMC
December 2008

Widespread CXCR4 activation in astrocytomas revealed by phospho-CXCR4-specific antibodies.

Cancer Res 2005 Dec;65(24):11392-9

Department of Pediatrics, Division of Pediatric Hematology/Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-0847DOI Listing
December 2005