Nicole L Gruta

Nicole L La Gruta

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Nicole L Gruta

Nicole L La Gruta

Publications by authors named "Nicole L La Gruta"

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1PubMed Central Citations

Simulation modelling for immunologists.

Nat Rev Immunol 2020 Mar 5;20(3):186-195. Epub 2019 Dec 5.

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41577-019-0235-3DOI Listing
March 2020

Modified Vaccinia Virus Ankara Can Induce Optimal CD8 T Cell Responses to Directly Primed Antigens Depending on Vaccine Design.

J Virol 2019 Nov 15;93(21). Epub 2019 Oct 15.

John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia

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http://dx.doi.org/10.1128/JVI.01154-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803277PMC
November 2019

The clock is ticking: the impact of ageing on T cell metabolism.

Clin Transl Immunology 2019 18;8(11):e01091. Epub 2019 Nov 18.

Department of Biochemistry Biomedicine Discovery Institute Monash University Clayton VIC Australia.

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http://dx.doi.org/10.1002/cti2.1091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859487PMC
November 2019

Characterisation of clinical and immune reactivity to barley and rye ingestion in children with coeliac disease.

Gut 2019 Aug 28. Epub 2019 Aug 28.

Immunology Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia

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http://dx.doi.org/10.1136/gutjnl-2019-319093DOI Listing
August 2019

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses.

Nat Commun 2019 06 28;10(1):2846. Epub 2019 Jun 28.

Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, 3800, Australia.

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http://dx.doi.org/10.1038/s41467-019-10661-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599079PMC
June 2019

CD4 T help promotes influenza virus-specific CD8 T cell memory by limiting metabolic dysfunction.

Proc Natl Acad Sci U S A 2019 03 20;116(10):4481-4488. Epub 2019 Feb 20.

Department of Microbiology and Immunology, The Peter Doherty Institute, University of Melbourne, Parkville, VIC 3000, Australia;

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http://dx.doi.org/10.1073/pnas.1808849116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410826PMC
March 2019

Most viral peptides displayed by class I MHC on infected cells are immunogenic.

Proc Natl Acad Sci U S A 2019 02 4;116(8):3112-3117. Epub 2019 Feb 4.

John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia;

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http://dx.doi.org/10.1073/pnas.1815239116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386720PMC
February 2019

Understanding the drivers of MHC restriction of T cell receptors.

Nat Rev Immunol 2018 07;18(7):467-478

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41577-018-0007-5DOI Listing
July 2018

Age-Related Decline in Primary CD8 T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8 T Cells.

Cell Rep 2018 06;23(12):3512-3524

Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia; Department of Microbiology and Immunology, The Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.057DOI Listing
June 2018

CD4CD8β double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin.

J Leukoc Biol 2017 09 21;102(3):837-844. Epub 2017 Jun 21.

The University of Queensland Diamantina Institute, Faculty of Medicine, University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia;

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http://doi.wiley.com/10.1189/jlb.1AB0217-065R
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http://dx.doi.org/10.1189/jlb.1AB0217-065RDOI Listing
September 2017

Targeted deletion of Traf2 allows immunosuppression-free islet allograft survival in mice.

Diabetologia 2017 04 6;60(4):679-689. Epub 2017 Jan 6.

Transplantation Immunology Group, Immunology Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW, 2010, Australia.

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http://dx.doi.org/10.1007/s00125-016-4198-7DOI Listing
April 2017

Corrigendum to ''Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host'' [J.Theor. Biol. 413 (2017) 34-49].

J Theor Biol 2017 04;419:394

School of Mathematics and Statistics, University of Melbourne, Parkville, VIC 3010, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Parkville, VIC 3010, Australia; Modelling and Simulation, Infection and Immunity Theme, Murdoch Children's Research Institute, Parkville, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jtbi.2017.03.015DOI Listing
April 2017

Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host.

J Theor Biol 2017 01 15;413:34-49. Epub 2016 Nov 15.

School of Mathematics and Statistics, University of Melbourne, Parkville, VIC 3010, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Parkville, VIC 3010, Australia; Modelling and Simulation, Infection and Immunity Theme, Murdoch Children's Research Institute, Parkville, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jtbi.2016.11.008DOI Listing
January 2017

Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response.

Immunity 2016 10 4;45(4):749-760. Epub 2016 Oct 4.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.09.007DOI Listing
October 2016

Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection.

J Exp Med 2016 08 8;213(9):1695-703. Epub 2016 Aug 8.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia

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http://dx.doi.org/10.1084/jem.20160312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995085PMC
August 2016

Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged mice.

Proc Natl Acad Sci U S A 2016 Feb 19;113(5):1333-8. Epub 2016 Jan 19.

Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia;

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http://dx.doi.org/10.1073/pnas.1525167113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747731PMC
February 2016

PTPN2 attenuates T-cell lymphopenia-induced proliferation.

Nat Commun 2014 ;5:3073

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1038/ncomms4073DOI Listing
November 2015

Consistency in polyclonal T-cell responses to gluten between children and adults with celiac disease.

Gastroenterology 2015 Nov 29;149(6):1541-1552.e2. Epub 2015 Jul 29.

Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Gastroenterology, The Royal Melbourne Hospital, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.07.013DOI Listing
November 2015

Antigen Specificity of Type I NKT Cells Is Governed by TCR β-Chain Diversity.

J Immunol 2015 Nov 30;195(10):4604-14. Epub 2015 Sep 30.

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria 3010, Australia; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Parkville, Victoria 3010, Australia;

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http://dx.doi.org/10.4049/jimmunol.1501222DOI Listing
November 2015

Sizing up the key determinants of the CD8(+) T cell response.

Nat Rev Immunol 2015 Nov 9;15(11):705-16. Epub 2015 Oct 9.

Department of Microbiology and Immunology, University of Melbourne, Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.

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http://dx.doi.org/10.1038/nri3905DOI Listing
November 2015

Paired TCRαβ analysis of virus-specific CD8(+) T cells exposes diversity in a previously defined 'narrow' repertoire.

Immunol Cell Biol 2015 Oct 25;93(9):804-14. Epub 2015 Mar 25.

Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute of Infection and Immunity, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1038/icb.2015.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618100PMC
October 2015

Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR α- and β-chain diversity in the face of peptide-MHC class I specificity.

J Immunol 2015 Feb 22;194(3):898-910. Epub 2014 Dec 22.

Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia; and

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http://dx.doi.org/10.4049/jimmunol.1401792DOI Listing
February 2015

T cell mediated immunity to influenza: mechanisms of viral control.

Trends Immunol 2014 Aug 16;35(8):396-402. Epub 2014 Jul 16.

Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria, 3010, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714906140010
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http://dx.doi.org/10.1016/j.it.2014.06.004DOI Listing
August 2014

The influenza virus-specific CTL immunodominance hierarchy in mice is determined by the relative frequency of high-avidity T cells.

J Immunol 2014 May 2;192(9):4061-8. Epub 2014 Apr 2.

Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.4049/jimmunol.1301403DOI Listing
May 2014

T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.

Nat Struct Mol Biol 2014 May 28;21(5):480-8. Epub 2014 Apr 28.

1] Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia. [2] Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK. [3] Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria, Australia. [4] [5].

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http://dx.doi.org/10.1038/nsmb.2817DOI Listing
May 2014

Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection.

Proc Natl Acad Sci U S A 2014 Jan 13;111(4):1485-90. Epub 2014 Jan 13.

Department of Microbiology and Immunology, University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Parkville, VIC 3010, Australia.

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http://dx.doi.org/10.1073/pnas.1323736111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910643PMC
January 2014

Interrogating the relationship between naïve and immune antiviral T cell repertoires.

Curr Opin Virol 2013 Aug 10;3(4):447-51. Epub 2013 Jul 10.

Department of Microbiology & Immunology, University of Melbourne, Parkville, VIC 3010, Australia.

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http://dx.doi.org/10.1016/j.coviro.2013.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779657PMC
August 2013

Influenza-induced, helper-independent CD8+ T cell responses use CD40 costimulation at the late phase of the primary response.

J Leukoc Biol 2013 Jan 29;93(1):145-54. Epub 2012 Oct 29.

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3052, Australia.

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http://dx.doi.org/10.1189/jlb.0612266DOI Listing
January 2013

Ecological analysis of antigen-specific CTL repertoires defines the relationship between naive and immune T-cell populations.

Proc Natl Acad Sci U S A 2013 Jan 14;110(5):1839-44. Epub 2013 Jan 14.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1222149110
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http://dx.doi.org/10.1073/pnas.1222149110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562793PMC
January 2013

Precursor frequency and competition dictate the HLA-A2-restricted CD8+ T cell responses to influenza A infection and vaccination in HLA-A2.1 transgenic mice.

J Immunol 2011 Aug 15;187(4):1895-902. Epub 2011 Jul 15.

Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Victoria, Australia.

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http://dx.doi.org/10.4049/jimmunol.1100664DOI Listing
August 2011

Effect of MHC class I diversification on influenza epitope-specific CD8+ T cell precursor frequency and subsequent effector function.

J Immunol 2011 Jun 2;186(11):6319-28. Epub 2011 May 2.

Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.4049/jimmunol.1000883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103778PMC
June 2011

Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses.

Proc Natl Acad Sci U S A 2011 Jun 23;108(23):9536-41. Epub 2011 May 23.

Department of Microbiology and Immunology, Bio21, Department of Biochemistry, University of Melbourne, Parkville, VIC 3010, Australia.

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http://dx.doi.org/10.1073/pnas.1106851108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111262PMC
June 2011

Influenza epitope-specific CD8+ T cell avidity, but not cytokine polyfunctionality, can be determined by TCRβ clonotype.

J Immunol 2010 Dec 1;185(11):6850-6. Epub 2010 Nov 1.

Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1002025
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http://dx.doi.org/10.4049/jimmunol.1002025DOI Listing
December 2010

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.

Nature 2010 Oct;467(7317):844-8

The Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1038/nature09448DOI Listing
October 2010

Multiplexed combinatorial tetramer staining in a mouse model of virus infection.

J Immunol Methods 2010 Aug 15;360(1-2):157-61. Epub 2010 Jun 15.

Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.jim.2010.06.003DOI Listing
August 2010

Altered CD8(+) T cell immunodominance after vaccinia virus infection and the naive repertoire in inbred and F(1) mice.

J Immunol 2010 Jan 30;184(1):45-55. Epub 2009 Nov 30.

Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.

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http://dx.doi.org/10.4049/jimmunol.0900999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845786PMC
January 2010

Functional implications of T cell receptor diversity.

Curr Opin Immunol 2009 Jun 11;21(3):286-90. Epub 2009 Jun 11.

Department of Microbiology and Immunology, The University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.coi.2009.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706259PMC
June 2009

Killer T cells in influenza.

Pharmacol Ther 2008 Nov 28;120(2):186-96. Epub 2008 Aug 28.

Department of Microbiology and Immunology, University of Melbourne, Royal Parade, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.pharmthera.2008.08.007DOI Listing
November 2008

Cell cycle-related acquisition of cytotoxic mediators defines the progressive differentiation to effector status for virus-specific CD8+ T cells.

J Immunol 2008 Sep;181(6):3818-22

Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.4049/jimmunol.181.6.3818DOI Listing
September 2008

A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo.

Proc Natl Acad Sci U S A 2008 Mar 28;105(9):3351-6. Epub 2008 Feb 28.

Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute and Department of Microbiology and Immunology, University of Melbourne, Victoria 3010, Australia.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0800137105
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http://dx.doi.org/10.1073/pnas.0800137105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265200PMC
March 2008

Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity.

Mol Immunol 2008 Feb 24;45(3):607-18. Epub 2007 Aug 24.

Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.molimm.2006.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237887PMC
February 2008

Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens.

Proc Natl Acad Sci U S A 2007 Nov 31;104(45):17753-8. Epub 2007 Oct 31.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1073/pnas.0708622104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077019PMC
November 2007

A question of self-preservation: immunopathology in influenza virus infection.

Immunol Cell Biol 2007 Feb-Mar;85(2):85-92. Epub 2007 Jan 9.

Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/sj.icb.7100026DOI Listing
May 2007

IL-18, but not IL-12, is required for optimal cytokine production by influenza virus-specific CD8+ T cells.

Eur J Immunol 2007 Feb;37(2):368-75

Department of Microbiology and Immunology, University of Melbourne, Parkville, Australia.

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http://doi.wiley.com/10.1002/eji.200636766
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http://dx.doi.org/10.1002/eji.200636766DOI Listing
February 2007

A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses.

Eur J Immunol 2006 Nov;36(11):2951-9

Department of Microbiology and Immunology, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1002/eji.200636390DOI Listing
November 2006

Establishment and recall of CD8+ T-cell memory in a model of localized transient infection.

Immunol Rev 2006 Jun;211:133-45

Department of Microbiology and Immunology, University of Melbourne, Parkville, Melbourne, Australia.

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http://dx.doi.org/10.1111/j.0105-2896.2006.00386.xDOI Listing
June 2006

A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies.

Proc Natl Acad Sci U S A 2006 Jan 17;103(4):994-9. Epub 2006 Jan 17.

Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Australia.

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http://dx.doi.org/10.1073/pnas.0510429103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1348014PMC
January 2006

Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.

Gastroenterology 2005 Sep;129(3):1005-18

Department of Medicine, University of Melbourne at Western Hospital, Footscray, Australia.

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http://dx.doi.org/10.1053/j.gastro.2005.06.068DOI Listing
September 2005

Contribution of T cell receptor affinity to overall avidity for virus-specific CD8+ T cell responses.

Proc Natl Acad Sci U S A 2005 Aug 1;102(32):11432-7. Epub 2005 Aug 1.

Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Melbourne, Australia.

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http://dx.doi.org/10.1073/pnas.0504851102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183580PMC
August 2005

Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression.

Proc Natl Acad Sci U S A 2005 Apr 14;102(17):6074-9. Epub 2005 Apr 14.

Department of Immunology, Hartwell Center for Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0501960102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087947PMC
April 2005

Characterization of CD8+ T cell repertoire diversity and persistence in the influenza A virus model of localized, transient infection.

Semin Immunol 2004 Jun;16(3):179-84

Department of Microbiology and Immunology, University of Melbourne, Parkville, Vic. 3010, Australia.

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http://dx.doi.org/10.1016/j.smim.2004.02.005DOI Listing
June 2004

Thymic expression of a gastritogenic epitope results in positive selection of self-reactive pathogenic T cells.

J Immunol 2004 May;172(10):5994-6002

Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Australia. Division of Immunobiology, University of Bonn, Bonn, Germany.

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http://dx.doi.org/10.4049/jimmunol.172.10.5994DOI Listing
May 2004

Differential tumor necrosis factor receptor 2-mediated editing of virus-specific CD8+ effector T cells.

Proc Natl Acad Sci U S A 2004 Mar 1;101(10):3545-50. Epub 2004 Mar 1.

Department of Immunology, St. Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0307347101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC373499PMC
March 2004

Architectural changes in the TCR:CD3 complex induced by MHC:peptide ligation.

J Immunol 2004 Mar;172(6):3662-9

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.4049/jimmunol.172.6.3662DOI Listing
March 2004

Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells.

J Immunol Methods 2002 Dec;271(1-2):137-51

Department of Immunology, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/s0022-1759(02)00343-5DOI Listing
December 2002

Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis.

Autoimmun Rev 2002 Oct;1(5):290-7

The Russell Grimwade School of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/s1568-9972(02)00066-6DOI Listing
October 2002

The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues.

J Immunol 2002 Jul;169(2):739-49

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.4049/jimmunol.169.2.739DOI Listing
July 2002