Nicolas Servant

Nicolas Servant

UNVERIFIED PROFILE

Are you Nicolas Servant?   Register this Author

Register author
Nicolas Servant

Nicolas Servant

Publications by authors named "Nicolas Servant"

Are you Nicolas Servant?   Register this Author

67Publications

2693Reads

11Profile Views

Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy.

Proc Natl Acad Sci U S A 2019 Nov 4. Epub 2019 Nov 4.

INSERM U981, LabEx LERMIT, Department of Molecular Medicine, Gustave Roussy Research Center, Université Paris Saclay, 94800 Villejuif, France;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1910824116DOI Listing
November 2019

Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors.

Cancer Cell 2019 Nov 7. Epub 2019 Nov 7.

PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2019.10.008DOI Listing
November 2019

Familial breast cancer and DNA repair genes: Insights into known and novel susceptibility genes from the GENESIS study, and implications for multigene panel testing.

Int J Cancer 2019 04 13;144(8):1962-1974. Epub 2018 Nov 13.

Inserm, Paris, France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ijc.31921
Publisher Site
http://dx.doi.org/10.1002/ijc.31921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587727PMC
April 2019

Transcriptome Profiling of Single Mouse Oocytes.

Methods Mol Biol 2018 ;1818:51-65

Institut Curie, PSL Research University, CNRS UMR3215, INSERM U934, UPMC Paris-Sorbonne, Paris, 75005, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-8603-3_7DOI Listing
March 2019

Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells.

Sci Rep 2019 Jan 29;9(1):888. Epub 2019 Jan 29.

Institut Curie, PSL Research University, INSERM U934, CNRS UMR3215, F-75248, Paris, Cedex 05, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-37301-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351556PMC
January 2019

Effective normalization for copy number variation in Hi-C data.

BMC Bioinformatics 2018 Sep 6;19(1):313. Epub 2018 Sep 6.

Institut Curie, PSL Research University, Paris, F-75005, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-018-2256-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127909PMC
September 2018

Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine Trials.

J Natl Cancer Inst 2016 Apr 23;108(4). Epub 2015 Nov 23.

Affiliations of authors:Department of Medical Oncology, Institut Curie , Paris & Saint-Cloud , France (CLT, MK, MA); EA7285 Versailles-St-Quentin-en-Yvelines University , France (CLT, RR); Investigational Cancer Therapeutics, M. D. Anderson Cancer Center , Houston, TX (AMT); Drug Development Program, Department of Medical Oncology and Hematology, Princess Margaret Hospital , Toronto , Canada (PB); Department of Genetics, Institut Curie , Paris , France (GP, CC, ER, IB); Department of Pathology, Institut Curie , Paris , France (AVS); Institut Curie / INSERM U900 , Paris , France (NS, XP); Department of Surgery, Institut Curie , Paris & Saint-Cloud , France (RR); Institut Curie, INSERM U830 , Paris , France (OD); EA7331, University of Paris-Descartes , Paris , France (IB).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djv362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830395PMC
April 2016

Design and statistical principles of the SHIVA trial.

Chin Clin Oncol 2015 Sep;4(3):32

Unité INSERM, Institut Curie, Mines ParisTech U900, Paris, France; Department of Medical Oncology, Clinical Trial Unit, Institut Curie, Paris and Saint-Cloud, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3978/j.issn.2304-3865.2015.02.02DOI Listing
September 2015

Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.

Nature 2015 Jul 11;523(7558):92-5. Epub 2015 May 11.

Institut Curie, Centre de Recherche, PSL Research University, CNRS UMR 168, Physicochimie Curie Mechanics and Genetics of Embryonic and Tumour Development, INSERM, Fondation Pierre-Gilles de Gennes, F-75005 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14329DOI Listing
July 2015

Epigenomic alterations in breast carcinoma from primary tumor to locoregional recurrences.

PLoS One 2014 6;9(8):e103986. Epub 2014 Aug 6.

UMR144, Oncology Molecular Team, Institut Curie, Paris, France; Department of translational research, Residual Tumor and Response to Treatment Team, Institut Curie, Paris, France; Department of Surgery, Institut Curie, Paris, France.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103986PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123987PMC
April 2015

Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.

Mol Cell 2015 Mar 22;57(5):769-783. Epub 2015 Jan 22.

Institut Curie, 26 Rue d'Ulm, 75005 Paris, France; INSERM U934, 26 Rue d'Ulm, 75005 Paris, France; CNRS UMR3215, 26 Rue d'Ulm, 75005 Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2014.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352895PMC
March 2015

Multi-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data.

Bioinformatics 2014 Dec 12;30(24):3443-50. Epub 2014 Jul 12.

Inserm, U900, Bioinformatics, Biostatistics, Epidemiology and Computational Systems Biology of Cancer, Institut Curie, Centre de Recherche, 26 rue d'Ulm, Paris 75248, Mines ParisTech, Fontainebleau 77300, Inserm, U830, Genetics and Biology of Cancers, Paris 75248, France, Institut de Pathologie et de Génétique, Gosselies 6041, Belgium, Clinical Research Department, Department of Medical Oncology, Plateforme de Génomique, Département de recherche translationnelle, Centre de recherche, Next-generation sequencing platform, Institut Curie, CNRS, UMR144, Subcellular Structure and cellular Dynamics, Paris 75248, France and OncoDNA, Gosselies 6041, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btu436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253825PMC
December 2014

[Biological network modelling and precision medicine in oncology].

Bull Cancer 2014 Jun;101 Suppl 1:S18-21

Institut Curie, 26 rue d'Ulm, 75248 Paris, France, INSERM U900, 75248 Paris, France, Mines ParisTech, 77300 Fontainebleau, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1684/bdc.2014.1973DOI Listing
June 2014

The spectrum of clinical trials aiming at personalizing medicine.

Chin Clin Oncol 2014 Jun;3(2):13

Institut Curie, Unité INSERM/Institut Curie U900, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3978/j.issn.2304-3865.2014.05.02DOI Listing
June 2014

Combinatorial flexibility of cytokine function during human T helper cell differentiation.

Nat Commun 2014 May 28;5:3987. Epub 2014 May 28.

1] INSERM U932, 26 rue d'Ulm, 75005 Paris, France [2] Section Recherche, Institut Curie, 26 rue d'Ulm, 75005 Paris, France [3] Laboratoire d'Immunologie Clinique, Institut Curie, 26 rue d'Ulm, 75005 Paris, France [4] CIC IGR Curie 1428, 26 rue d'Ulm, 75005 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms4987DOI Listing
May 2014

Developmental dynamics and disease potential of random monoallelic gene expression.

Dev Cell 2014 Feb;28(4):366-80

Institut Curie, 26 rue d'Ulm, Paris 75248, France; Genetics and Developmental Biology Unit, INSERM U934/CNRS UMR3215, Paris 75248, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2014.01.016DOI Listing
February 2014

A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis.

Brief Bioinform 2013 Nov 17;14(6):671-83. Epub 2012 Sep 17.

Institut Pasteur, PF2 Plate-forme Transcriptome et Epigénome, 28 rue du Dr Roux, Paris CEDEX 15, F-75724 France. Tel.: +33 (0) 145688651; Fax: +33 (0) 145688406;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bib/bbs046DOI Listing
November 2013

RNAi-dependent and independent control of LINE1 accumulation and mobility in mouse embryonic stem cells.

PLoS Genet 2013 11 7;9(11):e1003791. Epub 2013 Nov 7.

Swiss Federal Institute of Technology Zurich, Department of Biology, Chair of RNA biology, Zurich, Switzerland ; Institut Curie, CNRS UMR3215, Paris, France.

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pgen.1003791
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1003791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820764PMC
November 2013

Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation.

PLoS Genet 2009 Aug 28;5(8):e1000620. Epub 2009 Aug 28.

CNRS UPR2357-Institut de Biologie Moléculaire des Plantes, Université de Strasbourg, Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1000620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725319PMC
August 2009

A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses.

Nat Immunol 2008 Jun 4;9(6):650-7. Epub 2008 May 4.

Institut National de la Santé et de la Recherche Médicale U653, Paris F-75248, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.1613DOI Listing
June 2008

Ubiquinol-cytochrome-c reductase 7.2 kDa protein of mitochondrial complex III is steroid-responsive and increases in cardiac hypertrophy and hypertension.

Can J Physiol Pharmacol 2007 Oct;85(10):986-96

Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, 3755 chemin Côte Sainte Catherine, Montréal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1139/y07-086DOI Listing
October 2007

Goulphar: rapid access and expertise for standard two-color microarray normalization methods.

BMC Bioinformatics 2006 Oct 23;7:467. Epub 2006 Oct 23.

IFR36, Plate-forme Transcriptome, Ecole Normale Supérieure, 46 rue d'Ulm, 75230 Paris cedex05, France.

View Article

Download full-text PDF

Source
http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/1471-2105-7-467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1626094PMC
October 2006

Egr-1 negatively regulates expression of the sodium-calcium exchanger-1 in cardiomyocytes in vitro and in vivo.

Cardiovasc Res 2005 Jan;65(1):187-94

Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, 3755 chemin Côte Ste Catherine, Montréal, Québec, Canada H3T 1E2.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cardiores.2004.09.026DOI Listing
January 2005

TBP-associated factor 1 overexpression induces tolerance to Doxorubicin in confluent H9c2 cells by an increase in cdk2 activity and cyclin E expression.

Mol Cell Biochem 2004 Apr;259(1-2):71-81

Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1023/b:mcbi.0000021347.65073.10DOI Listing
April 2004

Chronic beta-adrenoreceptor stimulation in vivo decreased Bcl-2 and increased Bax expression but did not activate apoptotic pathways in mouse heart.

Can J Physiol Pharmacol 2004 Mar;82(3):167-74

Lady Davis Institute for Medical Research, Sir Mortimer B. Davis--Jewish General Hospital, Montréal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1139/y03-134DOI Listing
March 2004

Dexrazoxane does not protect against doxorubicin-induced damage in young rats.

Am J Physiol Heart Circ Physiol 2003 Aug 24;285(2):H499-506. Epub 2003 Apr 24.

Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, 3755 Chemin Cote, St. Catherine, Montréal, Canada, H3T 1E2.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00047.2003DOI Listing
August 2003