Nicolas Penel

Nicolas Penel

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Nicolas Penel

Nicolas Penel

Publications by authors named "Nicolas Penel"

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Overview of « druggable » alterations by histological subtypes of sarcomas and connective tissue intermediate malignancies.

Crit Rev Oncol Hematol 2020 Jun 14;150:102960. Epub 2020 Apr 14.

Biopathology department, Centre Oscar Lambret, Lille, France; Lille University, Inserm U1192, Laboratoire « Protéomique, Réponse Inflammatoire et Spectrométrie de Masse » (PRISM), Villeneuve d'Ascq, France.

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http://dx.doi.org/10.1016/j.critrevonc.2020.102960DOI Listing
June 2020

Maintenance therapy and drug holiday in sarcoma patients: systematic review.

Acta Oncol 2020 May 13:1-7. Epub 2020 May 13.

Medical School, Lille University, Lille, France.

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http://dx.doi.org/10.1080/0284186X.2020.1759825DOI Listing
May 2020

[Systemic treatment for management of aggressive fibromatosis in both adult and children: Level of evidence and unsolved questions].

Bull Cancer 2020 Mar 4;107(3):375-380. Epub 2019 Dec 4.

PSL université, Institut Curie, SIREDO Oncology Center (Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer), 26, rue d'Ulm, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.bulcan.2019.07.012DOI Listing
March 2020

[Desmoid type fibromatosis, from radical excision to molecular extirpation].

Bull Cancer 2020 Mar;107(3):344-345

Institut Curie, PSL university, SIREDO Oncology Center (Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer), 26, rue d'Ulm, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.bulcan.2020.02.006DOI Listing
March 2020

[2019 international oncology news: A compendium].

Bull Cancer 2020 Feb 10;107(2):148-156. Epub 2020 Feb 10.

Centre hospitalier universitaire Giscard d'Estaing, service thérapie cellulaire et hématologie clinique, 58, rue Montalembert, 63000 Clermont Ferrand, France.

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http://dx.doi.org/10.1016/j.bulcan.2020.01.010DOI Listing
February 2020

Emerging Role of Multikinase Inhibitors in Desmoid Tumor Management.

Am J Clin Oncol 2019 12;42(12):958

Clinical Research and Innovation Department Centre Oscar Lambret.

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http://dx.doi.org/10.1097/COC.0000000000000603DOI Listing
December 2019

Hormonal therapies in uterine sarcomas, aggressive angiomyxoma, and desmoid-type fibromatosis.

Crit Rev Oncol Hematol 2019 Nov 31;143:62-66. Epub 2019 Aug 31.

Medical School, Lille University, Lille, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10408428193017
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http://dx.doi.org/10.1016/j.critrevonc.2019.08.007DOI Listing
November 2019

Management of tumor tissue in cancer clinical trials: An ethical perspective.

Bull Cancer 2019 Nov 13;106(11):1064. Epub 2019 Sep 13.

Centre Oscar Lambret, department of clinical research and innovation, 3, rue Combemale, 59020 Lille cedex, France.

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http://dx.doi.org/10.1016/j.bulcan.2019.06.009DOI Listing
November 2019

Tyrosine kinase inhibitors and immune checkpoint inhibitors-induced thyroid disorders.

Crit Rev Oncol Hematol 2019 Sep 31;141:23-35. Epub 2019 May 31.

Department of Endocrinology and Metabolism, CHU Lille, 59037 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2019.05.015DOI Listing
September 2019

[Cancer screening words].

Bull Cancer 2019 Jul - Aug;106(7-8):608-614. Epub 2019 Apr 16.

Université de Lille, faculté de médecine Henri-Warembourg, 2, avenue Eugène-Avinée, 59120 Loos, France; Centre Oscar-Lambret, 3, rue Frédéric-Combemale, 59000 Lille, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00074551193015
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http://dx.doi.org/10.1016/j.bulcan.2019.03.004DOI Listing
July 2019

Personalised management of alveolar soft part sarcoma: a promising phase 2 study.

Lancet Oncol 2019 06 8;20(6):750-752. Epub 2019 May 8.

Department of Medical Oncology and University Claude Bernard, Léon Bérard Cancer Center, Lyon, France.

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http://dx.doi.org/10.1016/S1470-2045(19)30286-4DOI Listing
June 2019

From rare to well-done: importance of rare tumors in cancer therapeutic advances.

Oncotarget 2019 Jun 18;10(40):3998-3999. Epub 2019 Jun 18.

Oncology Medical Unit, CHU La Timone and Aix-Marseille University, Marseille, France.

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http://dx.doi.org/10.18632/oncotarget.27020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592290PMC
June 2019

[Evolution of the regulatory framework in clinical research].

Bull Cancer 2019 Apr 15;106(4):389-394. Epub 2019 Mar 15.

Centre Oscar-Lambret, direction de la recherche clinique et de l'innovation, 3, rue Combemale, 59020 Lille, France; Université Lille-Nord de France, faculté de médecine, place de Verdun, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2019.01.016DOI Listing
April 2019

Non-islet-cell tumour hypoglycaemia (NICTH): About a series of 6 cases.

Ann Endocrinol (Paris) 2019 Feb 16;80(1):21-25. Epub 2018 Mar 16.

Department of endocrinology and metabolism, CHRU Lille, 59037 Lille, France; UMR 1190 translational research in diabetes, Inserm, 59000 Lille, France; EGID (European Genomic Institute for Diabetes), university Lille, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.ando.2018.01.005DOI Listing
February 2019

"Impossible" patients in oncology: Two unusual cases.

Palliat Support Care 2019 02 27;17(1):119-121. Epub 2018 Jun 27.

Medical Oncology Department,Centre Oscar Lambret,Lille,59020,France.

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http://dx.doi.org/10.1017/S147895151800041XDOI Listing
February 2019

[Before seasonal influenza, vaccination of cancer patients and healthcare givers].

Bull Cancer 2019 Feb 30;106(2):94-96. Epub 2019 Jan 30.

Centre Oscar-Lambret, service de soins palliatifs, 3, rue Combemale, 59020 Lille cedex, France.

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http://dx.doi.org/10.1016/j.bulcan.2019.01.006DOI Listing
February 2019

[Epithelioid hemangioendothelioma].

Bull Cancer 2019 Jan 4;106(1):73-83. Epub 2018 Dec 4.

Centre Oscar Lambret, département d'oncologie médicale, 3, rue Frédéric Combemale, 59000 Lille, France; Hôpital Claude Huriez, service d'oncologie médicale, rue Michel Polonowski, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2018.11.004DOI Listing
January 2019

[Some important breakthroughs in oncology and hematology in 2018: A selection by the editorial board of Bulletin du Cancer].

Bull Cancer 2019 Jan 3;106(1):12-23. Epub 2019 Jan 3.

AP-HP, hôpitaux universitaires Paris Centre, hôpital Cochin, unité d'oncologie thoracique, service de pneumologie, 75014 Paris, France; Paris Descartes Université, centre de recherche des Cordeliers, équipe « cancer, immune control and escape », Inserm UMRS1138, 75006 Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00074551183040
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http://dx.doi.org/10.1016/j.bulcan.2018.12.005DOI Listing
January 2019

[Prostate cancer screening: Reasons of controversy].

Bull Cancer 2018 Dec 17;105(12):1111-1118. Epub 2018 Nov 17.

Centre Oscar-Lambret, département de cancérologie générale, 3, rue Combemale, 59020 Lille cedex, France; CHRU de Lille, hôpital Claude-Huriez, service universitaire d'oncologie médicale, rue Michel-Polonowski, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2018.09.007DOI Listing
December 2018

[What role for the direct oral anticoagulants in oncology?]

Bull Cancer 2018 Jul - Aug;105(7-8):631-633. Epub 2018 Jun 28.

Université Lille-Nord de France, faculté de médecine, place de Verdun, 59000 Lille, France; Département de cancérologie générale, centre Oscar-Lambret, 3, rue Combemale, 59020 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2018.05.015DOI Listing
November 2018

[Dermatofibrosarcoma: Management].

Bull Cancer 2018 Nov 5;105(11):1094-1101. Epub 2018 Oct 5.

Centre Oscar Lambret, département de cancérologie générale, 3, rue F. Combemale, 59020 Lille, France.

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http://dx.doi.org/10.1016/j.bulcan.2018.08.008DOI Listing
November 2018

[Adjuvant chemotherapy for upper tract urothelial cancer: Level of evidence IA].

Bull Cancer 2018 Oct 17;105(10):853-854. Epub 2018 Sep 17.

Centre Oscar-Lambret, département de cancérologie générale, 3, rue Combemale, 59020 Lille cedex, France; Hôpital Claude-Huriez, service universitaire d'oncologie médicale, rue Michel-Polonowski, 59037 Lille cedex, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00074551183023
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http://dx.doi.org/10.1016/j.bulcan.2018.07.017DOI Listing
October 2018

Reappraisal of eligibility criteria in cancer clinical trials.

Curr Opin Oncol 2018 09;30(5):352-357

Clinical Research and Innovation Department, Centre Oscar Lambret.

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http://dx.doi.org/10.1097/CCO.0000000000000470DOI Listing
September 2018

Efficacy and safety of regorafenib compared to placebo and to post-cross-over regorafenib in advanced non-adipocytic soft tissue sarcoma.

Eur J Cancer 2018 08 11;99:28-36. Epub 2018 Jun 11.

Department of Clinical Research and Innovation, Centre Oscar Lambret, 3 rue Combemale, 59000 Lille, France; Paris-Saclay University, Univ. Paris-Sud, CESP, INSERM, Gustave Roussy, 94805 Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.05.008DOI Listing
August 2018

[2017 ASCO: Complete androgen blockade strikes back].

Authors:
Nicolas Penel

Bull Cancer 2017 Jul - Aug;104(7-8):599-601. Epub 2017 Jul 5.

Département de cancérologie générale, centre Oscar-Lambret, 3, rue F.-Combemale, 59020 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2017.06.001DOI Listing
June 2018

[Requirement of DPD deficiency screening before prescription of fluoropyrimidines].

Authors:
Nicolas Penel

Bull Cancer 2018 04;105(4):331-332

Centre Oscar-Lambret, département de cancérologie générale, 3, rue Frédéric-Combemale, 59000 Lille, France; Service d'oncologie médicale, hôpital Claude Huriez, CHRU de Lille, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2018.03.001DOI Listing
April 2018

Efficacy and safety of Sm-EDTMP as treatment of painful bone metastasis: a large single-center study.

Support Care Cancer 2018 Mar 17;26(3):751-758. Epub 2017 Sep 17.

Medical Oncology Department, Oscar Lambret Center, Lille, France.

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http://dx.doi.org/10.1007/s00520-017-3885-3DOI Listing
March 2018

[Autoimmune hypophysitis associated with new anti-cancer immunotherapies].

Bull Cancer 2018 Mar 21;105(3):275-280. Epub 2018 Feb 21.

Centre Oscar-Lambret, département de cancérologie générale, 3, rue F.-Combemale, 59020 Lille, France; CHRU de Lille, hôpital Claude-Huriez, service d'oncologie médicale, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2017.10.033DOI Listing
March 2018

Meta-analyses evaluating surrogate endpoints for overall survival in cancer randomized trials: A critical review.

Crit Rev Oncol Hematol 2018 Mar 23;123:21-41. Epub 2017 Nov 23.

Clinical and Epidemiological Research Unit, Institut Bergonié, Comprehensive Cancer Center, 229 Cours de l'Argonne, 33000 Bordeaux, France; INSERM CIC-EC 14.01 (Clinical Epidemiology), Bordeaux, France; INSERM, ISPED, Centre INSERM U1219 Bordeaux Population Health Center, Epicene Team, 146 Rue Léo Saignat, 33076 Bordeaux, France; University of Bordeaux, ISPED, Centre INSERM U1219 Bordeaux Population Health, Epicene Team, 146 Rue Léo Saignat, 33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2017.11.014DOI Listing
March 2018

A noninterventional, multicenter, prospective phase IV study of trabectedin in patients with advanced soft tissue sarcoma.

Anticancer Drugs 2017 11;28(10):1157-1165

aDepartment of Oncology, Medical Oncology, CRO, National Cancer Institute (IRCCS), Aviano (PN), Italy bSarcoma Unit, Medical Oncology, Royal Marsden Hospital, London, UK cLocomotive Apparatus Tumor Unit, Orthopedic Service, Coimbra University Medical Center, Coimbra, Portugal dSarcoma Unit, Interdisciplinary Tumor Center, Mannheim University Medical Center, University of Heidelberg, Germany eMedical Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain fMedical Oncology, L'Institut Roi Albert II, Bruxelles, Belgium gClinical Division of Oncology, Medical University Vienna - General Hospital, Austria hCentre Oscar Lambret, General Oncology, Lille, France.

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http://dx.doi.org/10.1097/CAD.0000000000000560DOI Listing
November 2017

[Prostate cancer and DNA repair genes].

Authors:
Nicolas Penel

Bull Cancer 2017 Nov 9;104(11):958-961. Epub 2017 Oct 9.

Centre Oscar-Lambret, département de cancérologie générale, 3, rue F.-Combemale, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2017.07.005DOI Listing
November 2017

How to emerge from the conservatism in clinical research methodology?

Curr Opin Oncol 2017 Sep;29(5):400-404

aMedical Oncology Department, Oscar Lambret Center, Lille, France bMedical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.

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http://dx.doi.org/10.1097/CCO.0000000000000399DOI Listing
September 2017

[Tyrosine kinase inhibitor as adjuvant treatment of renal cell carcinoma: 1 versus 3].

Authors:
Nicolas Penel

Bull Cancer 2017 Sep 29;104(9):705-706. Epub 2017 Jul 29.

Centre Oscar-Lambret, département de cancérologie générale, 3, rue F.-Combemale, 59020 Lille cedex, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00074551173019
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http://dx.doi.org/10.1016/j.bulcan.2017.06.015DOI Listing
September 2017

Life-Threatening Irinotecan-Induced Toxicity in an Adult Patient with Alveolar Rhabdomyosarcoma: The Role of a UGT1A1 Polymorphism.

Case Rep Oncol Med 2017 26;2017:2683478. Epub 2017 Sep 26.

Medical Oncology Department, Oscar Lambret Cancer Centre, Lille, France.

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http://dx.doi.org/10.1155/2017/2683478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634569PMC
September 2017

Adult desmoid tumors: biology, management and ongoing trials.

Curr Opin Oncol 2017 Jul;29(4):268-274

aDepartment of Medical Oncology, Centre Oscar Lambret, Lille bDepartment of Biopathology, Institut Bergonié, Comprehensive Cancer Centre, Institut National de la Santé et de la Recherche Medicale (INSERM) U916, Bordeaux cDivision of Adult Oncology, Department of Medicine, Aix-Marseille Université, INSERM U910 and Timone Hospital, Marseille, France.

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http://dx.doi.org/10.1097/CCO.0000000000000374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470853PMC
July 2017

First-line management of metastatic castrate-resistant prostate cancer patients: Audit of real-life practices.

Bull Cancer 2017 Jun 5;104(6):552-558. Epub 2017 Apr 5.

Centre Oscar-Lambret, medical oncology department, 3, rue F.-Combemale, 59020 Lille, France; SIRIC ONCOLille Consortium, Clinical Research and Methodology Platform, 59000 Lille, France.

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http://dx.doi.org/10.1016/j.bulcan.2017.02.002DOI Listing
June 2017

[Incidence and risk factors for ifosfamide-related encephalopathy in sarcoma patients].

Bull Cancer 2017 Mar 13;104(3):208-212. Epub 2016 Dec 13.

Centre Oscar-Lambret, département d'oncologie médicale, 3, rue Combemale, 59020 Lille cedex, France; CHRU de Lille, SIRIC OncoLille, 2, avenue Oscar-Lambret, 59037 Lille cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.11.007DOI Listing
March 2017

[β-catenin and desmoid tumors: The ideal biomarker?]

Authors:
Nicolas Penel

Bull Cancer 2017 Mar 20;104(3):205-207. Epub 2016 Dec 20.

Centre Oscar-Lambret, département de cancérologie générale, 3, rue F-Combemale, 59020 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.11.019DOI Listing
March 2017

[Carcinoma of unknown primary site: From necropsy to epigenetic analysis].

Authors:
Nicolas Penel

Bull Cancer 2017 Feb 29;104(2):112-113. Epub 2016 Nov 29.

Centre Oscar-Lambret, département de cancérologie générale, 3, rue F-Combemale, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.10.022DOI Listing
February 2017

[Which recent results in Oncology and Hematology will have an impact on our practices? The point of vue of Bulletin du Cancer editorial board].

Bull Cancer 2017 Jan 19;104(1):6-19. Epub 2016 Dec 19.

CHU de Clermont-Ferrand, service de thérapie cellulaire et d'hématologie clinique adulte, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France.

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http://dx.doi.org/10.1016/j.bulcan.2016.11.009DOI Listing
January 2017

[Usefulness of social and educational approach in adolescents and young adults with cancer: The Lille team's experience].

Bull Cancer 2016 Dec 22;103(12):1011-1018. Epub 2016 Nov 22.

Centre de lutte contre le cancer Oscar-Lambret, unité d'onco-pédiatrie, 3, rue Frédéric-Combemale, 59000 Lille, France.

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http://dx.doi.org/10.1016/j.bulcan.2016.10.019DOI Listing
December 2016

Crossed views of burden and emotional distress of cancer patients and family caregivers during palliative care.

Psychooncology 2016 11 3;25(11):1278-1285. Epub 2015 Dec 3.

UDL3, SCALAB UMR CNRS 9193, Université de Lille, Villeneuve d'Ascq, France.

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http://dx.doi.org/10.1002/pon.4056DOI Listing
November 2016

PRognostic factor of Early Death In phase II Trials or the end of 'sufficient life expectancy' as an inclusion criterion? (PREDIT model).

BMC Cancer 2016 10 4;16(1):768. Epub 2016 Oct 4.

Department of Medical Oncology, Institut Bergonié, Comprehensive Cancer Centre Bordeaux, 229 cours de l'Argonne, 33076, Bordeaux, France.

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http://dx.doi.org/10.1186/s12885-016-2819-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050995PMC
October 2016

[Anti-PLD1 and anti-PD1 in advanced urothelial cancers: promises from early phase trials].

Authors:
Nicolas Penel

Bull Cancer 2016 Oct 4;103(10):811-812. Epub 2016 Oct 4.

Centre Oscar-Lambret, 3, rue Frédéric-Combemale, 59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.08.005DOI Listing
October 2016

Inappropriate dose of multitargeted tyrosine kinase inhibitors: the original sin.

Curr Opin Oncol 2016 09;28(5):437-40

Department of Medical Oncology, Centre Oscar Lambret, Lille, France.

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http://dx.doi.org/10.1097/CCO.0000000000000319DOI Listing
September 2016

[Splicing variant of androgen receptors (AR-V7): New paradigms].

Authors:
Nicolas Penel

Bull Cancer 2016 Sep 31;103(9):711-3. Epub 2016 Aug 31.

Centre Oscar-Lambret, Department of Medical Oncology, 3, rue Frédéric-Combemale, 59020, Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.07.005DOI Listing
September 2016

[ASCO 2016: Confirmation of respective roles of docetaxel and cabazitaxel in prostate cancer patients].

Authors:
Nicolas Penel

Bull Cancer 2016 Sep 3;103(9):714-6. Epub 2016 Sep 3.

Centre Oscar-Lambret, Department of Medical Oncology, 3, rue Frédéric-Combemale, 59020 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.07.006DOI Listing
September 2016

Reporting adverse events in cancer surgery randomized trials: A systematic review of published trials in oesophago-gastric and gynecological cancer patients.

Crit Rev Oncol Hematol 2016 Aug 7;104:108-14. Epub 2016 Jun 7.

Lille Nord de France University, Medical School (Research Unit EA 2694), Lille, France; SIRIC OncoLille Consortium, Lille, France; Clinical Research Unit, Oscar Lambret Cancer Centre, Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2016.05.017DOI Listing
August 2016

[Phase 1 of clinical trial: The issue of dose-escalating].

Authors:
Nicolas Penel

Bull Cancer 2016 Jun;103(6):511-2

SIRIC OncoLille Consortium, Clinical Research and Methodology Platform, 59037 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.05.001DOI Listing
June 2016