Publications by authors named "Nicolas Mermod"

52Publications

Genome-wide analysis of single nucleotide variants allows for robust and accurate assessment of clonal derivation in cell lines used to produce biologics.

Biotechnol Bioeng 2020 Aug 11. Epub 2020 Aug 11.

Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Switzerland.

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August 2020

Transient vitamin B5 starving improves mammalian cell homeostasis and protein production.

Metab Eng 2020 07 2;60:77-86. Epub 2020 Apr 2.

Center for Biotechnology and Department of Fundamental Microbiology, University of Lausanne, UNIL-EPFL, Lausanne, Switzerland.

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July 2020

Influence of cytoskeleton organization on recombinant protein expression by CHO cells.

Biotechnol Bioeng 2020 04 23;117(4):1117-1126. Epub 2020 Feb 23.

Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.

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April 2020

Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells.

Biotechnol Bioeng 2020 04 23;117(4):1101-1116. Epub 2020 Feb 23.

Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.

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April 2020

Characterization of mesoangioblast cell fate and improved promyogenic potential of a satellite cell-like subpopulation upon transplantation in dystrophic murine muscles.

Stem Cell Res 2019 12 25;41:101619. Epub 2019 Oct 25.

Institute of Biotechnology and Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland. Electronic address:

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December 2019

A role for alternative end-joining factors in homologous recombination and genome editing in Chinese hamster ovary cells.

DNA Repair (Amst) 2019 10 15;82:102691. Epub 2019 Aug 15.

Institute of Biotechnology and Department of Fundamental Microbiology, University of Lausanne, 1015 Lausanne, Switzerland. Electronic address:

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October 2019

Automated microfluidic sorting of mammalian cells labeled with magnetic microparticles for those that efficiently express and secrete a protein of interest.

Biotechnol Bioeng 2017 08 6;114(8):1791-1802. Epub 2017 Jun 6.

Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland.

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August 2017

MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering.

Biotechnol Bioeng 2017 02 3;114(2):384-396. Epub 2016 Oct 3.

Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland.

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February 2017

Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms.

Nucleic Acids Res 2016 Apr 10;44(6):e56. Epub 2015 Dec 10.

Institute of Biotechnology, University of Lausanne, and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland

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April 2016

A role for homologous recombination proteins in cell cycle regulation.

Cell Cycle 2015 30;14(17):2853-61. Epub 2015 Jun 30.

a Institute of Biotechnology ; University of Lausanne ; and Center for Biotechnology UNIL-EPFL ; Lausanne , Switzerland.

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June 2016

A PiggyBac-mediated approach for muscle gene transfer or cell therapy.

Stem Cell Res 2014 Nov 8;13(3 Pt A):390-403. Epub 2014 Sep 8.

Institute of Biotechnology, University of Lausanne and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland. Electronic address:

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November 2014

Nuclear Factor I-C acts as a regulator of hepatocyte proliferation at the onset of liver regeneration.

Liver Int 2015 Apr 25;35(4):1185-94. Epub 2014 Oct 25.

Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.

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April 2015

Assessing dystrophies and other muscle diseases at the nanometer scale by atomic force microscopy.

Nanomedicine (Lond) 2014 Apr;9(4):393-406

Laboratory of Molecular Biotechnology, Center for Biotechnology UNIL-EPFL & Institute of Biotechnology, University of Lausanne, Station 6, EPFL, 1015 Lausanne, Switzerland

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April 2014

Extracellular deposition of matrilin-2 controls the timing of the myogenic program during muscle regeneration.

J Cell Sci 2014 Aug 3;127(Pt 15):3240-56. Epub 2014 Jun 3.

Institute of Biochemistry, Biological Research Centre, Hungarian Academy of Sciences, Szeged, H-6701 Szeged, Hungary Avidin Ltd., H-6726 Szeged, Hungary

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August 2014

Gene expression changes in chronic inflammatory demyelinating polyneuropathy skin biopsies.

J Neuroimmunol 2014 May 11;270(1-2):61-6. Epub 2014 Mar 11.

Department of Clinical Neurosciences, Nerve-Muscle Unit, Lausanne University Hospital (CHUV), rue du Bugnon 46, CH-1011 Lausanne, Switzerland. Electronic address:

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May 2014

Optimization of the piggyBac transposon using mRNA and insulators: toward a more reliable gene delivery system.

PLoS One 2013 3;8(12):e82559. Epub 2013 Dec 3.

GICC, UMR CNRS 7292, Université François Rabelais, Tours, France ; Institute of Biotechnology, University of Lausanne, and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland ; PRC, UMR INRA-CNRS 7247, Centre INRA Val de Loire, Nouzilly, France.

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February 2015