Nicolas G Bazan

Nicolas G Bazan

UNVERIFIED PROFILE

Are you Nicolas G Bazan?   Register this Author

Register author
Nicolas G Bazan

Nicolas G Bazan

Publications by authors named "Nicolas G Bazan"

Are you Nicolas G Bazan?   Register this Author

100Publications

1855Reads

6Profile Views

Learning from the Fly Photoreceptor on How Synapses Integrate Gene Expression to Sustain Retina and Brain Function.

Neuron 2019 02;101(4):548-550

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2019.02.004DOI Listing
February 2019

Stereoselective Synthesis of Maresin-like Lipid Mediators.

Synlett 2019 Feb 14;30(3):343-347. Epub 2019 Jan 14.

Department of Comprehensive Dentistry & Biomaterials, Louisiana State University Health Sciences Center, School of Dentistry, 1100 Florida Ave., New Orleans, LA 70119, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0037-1612011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510270PMC
February 2019

Quantifying the relationship between optical anatomy and retinal physiological sensitivity: A comparative approach.

J Comp Neurol 2018 12 31;526(18):3045-3057. Epub 2018 Oct 31.

Neuroscience Center, Louisiana State University School of Medicine, New Orleans, Louisiana.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/cne.24531
Publisher Site
http://dx.doi.org/10.1002/cne.24531DOI Listing
December 2018

Docosanoids and elovanoids from omega-3 fatty acids are pro-homeostatic modulators of inflammatory responses, cell damage and neuroprotection.

Authors:
Nicolas G Bazan

Mol Aspects Med 2018 12 1;64:18-33. Epub 2018 Oct 1.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mam.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204315PMC
December 2018

Synthesis, hepatotoxic evaluation and antipyretic activity of nitrate ester analogs of the acetaminophen derivative SCP-1.

Bioorg Med Chem Lett 2018 12 17;28(23-24):3798-3801. Epub 2018 Sep 17.

Department of Chemistry, University of New Orleans, New Orleans, LA 71048 USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0960894X183075
Publisher Site
http://dx.doi.org/10.1016/j.bmcl.2018.09.020DOI Listing
December 2018

Platelet-Activating Factor (PAF) Receptor Antagonism Modulates Inflammatory Signaling in Experimental Uveitis.

Curr Eye Res 2018 06 11;43(6):821-827. Epub 2018 Apr 11.

a Department of Ophthalmology, School of Medicine , Louisiana State University Health Sciences Center , New Orleans , LA , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/02713683.2018.1454476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203441PMC
June 2018

Retinal Pigment Epithelium and Photoreceptor Preconditioning Protection Requires Docosanoid Signaling.

Cell Mol Neurobiol 2018 May 24;38(4):901-917. Epub 2017 Nov 24.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10571-017-0565-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882642PMC
May 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Stereoselective Total Synthesis of Macrophage-Produced Prohealing 14,21-Dihydroxy Docosahexaenoic Acids.

J Org Chem 2018 01 27;83(1):154-166. Epub 2017 Dec 27.

Department of Bioengineering, Tokyo Institute of Technology , Box B-52, Nagatsuta-cho 4259, Midori-ku, Yokohama 226-8501, Japan.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.joc.7b02510
Publisher Site
http://dx.doi.org/10.1021/acs.joc.7b02510DOI Listing
January 2018

Defining a mechanistic link between pigment epithelium-derived factor, docosahexaenoic acid, and corneal nerve regeneration.

J Biol Chem 2017 11 26;292(45):18486-18499. Epub 2017 Sep 26.

From the Department of Ophthalmology and Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, Louisiana 70112-2223

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M117.801472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682960PMC
November 2017

Thematic Minireview Series: Inflammatory transcription confronts homeostatic disruptions.

J Biol Chem 2017 07 14;292(30):12373-12374. Epub 2017 Jun 14.

the Department of Food Science and the Rutgers Center for Lipid Research, New Jersey Institute for Food, Nutrition, and Health, Rutgers University, New Brunswick, New Jersey 08901.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.R117.801753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535012PMC
July 2017

Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection.

J Biol Chem 2017 07 14;292(30):12390-12397. Epub 2017 Jun 14.

From the Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, Louisiana 70112-2223

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.R117.783076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535015PMC
July 2017

Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke.

Cell Death Differ 2017 06 21;24(6):1091-1099. Epub 2017 Apr 21.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/cdd.2017.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442474PMC
June 2017

Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism.

Sci Rep 2016 07 22;6:30298. Epub 2016 Jul 22.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep30298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957208PMC
July 2016

Molecular Principles for Decoding Homeostasis Disruptions in the Retinal Pigment Epithelium: Significance of Lipid Mediators to Retinal Degenerative Diseases.

Authors:
Nicolas G Bazan

Adv Exp Med Biol 2016 ;854:385-91

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, 70112, New Orleans, LA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-17121-0_51DOI Listing
April 2016

Hippocampal neuro-networks and dendritic spine perturbations in epileptogenesis are attenuated by neuroprotectin d1.

PLoS One 2015 24;10(1):e0116543. Epub 2015 Jan 24.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116543PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305283PMC
February 2016

The Docosanoid Neuroprotectin D1 Induces TH-Positive Neuronal Survival in a Cellular Model of Parkinson's Disease.

Cell Mol Neurobiol 2015 Nov 6;35(8):1127-36. Epub 2015 Jun 6.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA, 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10571-015-0206-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602058PMC
November 2015

Interferon-Stimulated Gene 15 Upregulation Precedes the Development of Blood-Brain Barrier Disruption and Cerebral Edema after Traumatic Brain Injury in Young Mice.

J Neurotrauma 2015 Jul 6;32(14):1101-8. Epub 2015 May 6.

1 Neuroscience Center of Excellence, Louisiana State University Health Sciences Center , New Orleans, Louisiana.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/neu.2014.3611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504440PMC
July 2015

Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival.

Nat Commun 2015 Mar 4;6:6228. Epub 2015 Mar 4.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms7228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351799PMC
March 2015

Acute treatment with docosahexaenoic acid complexed to albumin reduces injury after a permanent focal cerebral ischemia in rats.

PLoS One 2013 23;8(10):e77237. Epub 2013 Oct 23.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077237PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806755PMC
February 2015

Docosahexaenoic acid improves behavior and attenuates blood-brain barrier injury induced by focal cerebral ischemia in rats.

Exp Transl Stroke Med 2015 28;7(1). Epub 2015 Jan 28.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA 70112 USA ; Department of Neurosurgery, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA 70112 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13231-014-0012-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312454PMC
February 2015

Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging--impact of Bcl-2 and NPD-1 like metabolites.

Prostaglandins Leukot Essent Fatty Acids 2015 Jan 9;92:23-31. Epub 2014 Jun 9.

Department of Pharmacology, Goethe-University of Frankfurt, D-60438 Frankfurt, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.plefa.2014.05.008DOI Listing
January 2015

Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes.

Am J Physiol Cell Physiol 2014 Dec 1;307(11):C1058-67. Epub 2014 Oct 1.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana; Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Louisiana;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpcell.00270.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254953PMC
December 2014

Is there a molecular logic that sustains neuronal functional integrity and survival? Lipid signaling is necessary for neuroprotective neuronal transcriptional programs.

Authors:
Nicolas G Bazan

Mol Neurobiol 2014 Aug 19;50(1):1-5. Epub 2014 Sep 19.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA, 70112, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-014-8897-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381928PMC
August 2014

Docosahexaenoic acid and its derivative neuroprotectin D1 display neuroprotective properties in the retina, brain and central nervous system.

Nestle Nutr Inst Workshop Ser 2013 29;77:121-31. Epub 2013 Aug 29.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, LA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000351395DOI Listing
April 2014

Spatial organization of lipids in the human retina and optic nerve by MALDI imaging mass spectrometry.

J Lipid Res 2014 Mar 23;55(3):504-15. Epub 2013 Dec 23.

Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M044990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934734PMC
March 2014

Docosahexaenoic acid confers enduring neuroprotection in experimental stroke.

J Neurol Sci 2014 Mar 31;338(1-2):135-41. Epub 2013 Dec 31.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2013.12.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943637PMC
March 2014

Docosahexaenoic acid complexed to albumin provides neuroprotection after experimental stroke in aged rats.

Neurobiol Dis 2014 Feb 21;62:1-7. Epub 2013 Sep 21.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA; Department of Neurosurgery, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA. Electronic address:

View Article

Download full-text PDF

Source
http://stroke.ahajournals.org/content/36/1/118.full.pdf
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S096999611300254
Publisher Site
http://dx.doi.org/10.1016/j.nbd.2013.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877728PMC
February 2014

Mediator lipidomics in ophthalmology: targets for modulation in inflammation, neuroprotection and nerve regeneration.

Curr Eye Res 2013 Oct;38(10):995-1005

Neuroscience Center of Excellence and Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/02713683.2013.827211DOI Listing
October 2013

Inhibition of Myosin light-chain kinase attenuates cerebral edema after traumatic brain injury in postnatal mice.

J Neurotrauma 2013 Oct 28;30(19):1672-9. Epub 2013 Aug 28.

1 Neuroscience Center of Excellence, Louisiana State University Health Sciences Center , New Orleans, Louisiana.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/neu.2013.2898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787387PMC
October 2013

Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein.

J Neurosci 2013 Oct;33(44):17458-68

Department of Ophthalmology and Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, Electron Microscope Laboratory, Tulane University, New Orleans, Louisiana 70118, Department of Ophthalmology, Georgia Health Sciences University, Augusta, Georgia 30912, and Jules Stein Eye Institute, The University of California, Los Angeles School of Medicine, Los Angeles, California 90095.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.1380-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812510PMC
October 2013

Microglial ramification and redistribution concomitant with the attenuation of choroidal neovascularization by neuroprotectin D1.

Mol Vis 2013 4;19:1747-59. Epub 2013 Aug 4.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, LA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733904PMC
September 2013

N-3 fatty acid rich triglyceride emulsions are neuroprotective after cerebral hypoxic-ischemic injury in neonatal mice.

PLoS One 2013 20;8(2):e56233. Epub 2013 Feb 20.

Institute of Human Nutrition, Department of Pediatrics, College of Physicians and Surgeons of Columbia University, New York, New York, USA.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056233PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577805PMC
August 2013

Neuroprotectin D1 restores corneal nerve integrity and function after damage from experimental surgery.

Invest Ophthalmol Vis Sci 2013 Jun 12;54(6):4109-16. Epub 2013 Jun 12.

Department of Ophthalmology, University of Illinois Medical Center, Chicago, Illinois, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.13-12075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681478PMC
June 2013

Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness.

Nat Med 2013 Mar 4;19(3):345-50. Epub 2013 Feb 4.

Neuroscience Center and Department of Otorhinolaryngology & Biocommunications, Louisiana State University Health Sciences Center (LSUHSC), New Orleans, Louisiana, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.3106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657744PMC
March 2013

Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.

J Neurosci 2013 Feb;33(7):3178-89

Department of Ophthalmology and Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2428-12.2
Publisher Site
http://dx.doi.org/10.1523/JNEUROSCI.2428-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625017PMC
February 2013

Docosahexaenoic acid complexed to human albumin in experimental stroke: neuroprotective efficacy with a wide therapeutic window.

Exp Transl Stroke Med 2012 Sep 14;4(1):19. Epub 2012 Sep 14.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/2040-7378-4-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540001PMC
September 2012

Neuroinflammation and proteostasis are modulated by endogenously biosynthesized neuroprotectin D1.

Authors:
Nicolas G Bazan

Mol Neurobiol 2012 Aug 7;46(1):221-6. Epub 2012 Sep 7.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-012-8322-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477672PMC
August 2012

Ataxin-1 poly(Q)-induced proteotoxic stress and apoptosis are attenuated in neural cells by docosahexaenoic acid-derived neuroprotectin D1.

J Biol Chem 2012 Jul 16;287(28):23726-39. Epub 2012 Apr 16.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.287078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390647PMC
July 2012

Stereocontrolled total synthesis of neuroprotectin D1 / protectin D1 and its aspirin-triggered stereoisomer.

Tetrahedron Lett 2012 Apr 14;53(14):1695-1698. Epub 2012 Jan 14.

Department of Chemistry and Loker Hydrocarbon Research Institute, University of Southern California, Los Angeles, CA, 90089, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00404039120005
Publisher Site
http://dx.doi.org/10.1016/j.tetlet.2012.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370686PMC
April 2012

Endogenous signaling by omega-3 docosahexaenoic acid-derived mediators sustains homeostatic synaptic and circuitry integrity.

Mol Neurobiol 2011 Oct 15;44(2):216-22. Epub 2011 Sep 15.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA, 70112, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-011-8200-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180614PMC
October 2011

Neuroprotectin D1 modulates the induction of pro-inflammatory signaling and promotes retinal pigment epithelial cell survival during oxidative stress.

Adv Exp Med Biol 2010 ;664:663-70

Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4419-1399-9_76DOI Listing
September 2011

The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis.

Epilepsia 2011 Sep 13;52(9):1601-8. Epub 2011 May 13.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, Louisiana, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1528-1167.2011.03081.xDOI Listing
September 2011

Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection.

J Neurosci 2011 Sep;31(39):13710-21

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.3544-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197234PMC
September 2011

Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases.

Annu Rev Nutr 2011 Aug;31:321-51

Neuroscience Center of Excellence and Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev.nutr.012809.104635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406932PMC
August 2011

Novel proresolving aspirin-triggered DHA pathway.

Chem Biol 2011 Aug;18(8):976-87

Center for Experimental Therapeutics and Reperfusion Injury, Harvard Institutes of Medicine, Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chembiol.2011.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164791PMC
August 2011

Aspirin-triggered lipoxin A4 (15-epi-LXA4) increases the endothelial viability of human corneas storage in Optisol-GS.

J Ocul Pharmacol Ther 2011 Jun 6;27(3):235-41. Epub 2011 May 6.

Neuroscience Center of Excellence, Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jop.2010.0187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107975PMC
June 2011

EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation.

Invest Ophthalmol Vis Sci 2011 Apr 6;52(5):2240-9. Epub 2011 Apr 6.

Department of Ophthalmology and Neuroscience Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.10-6199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080170PMC
April 2011

Neuroprotectin D1 induces neuronal survival and downregulation of amyloidogenic processing in Alzheimer's disease cellular models.

Mol Neurobiol 2011 Apr 10;43(2):131-8. Epub 2011 Mar 10.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-011-8174-4DOI Listing
April 2011

Spatial correlation of mouse photoreceptor-RPE thickness between SD-OCT and histology.

Exp Eye Res 2011 Feb 28;92(2):155-60. Epub 2010 Oct 28.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2010.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169798PMC
February 2011

NPD1 induction of retinal pigment epithelial cell survival involves PI3K/Akt phosphorylation signaling.

Neurochem Res 2010 Dec 7;35(12):1944-7. Epub 2010 Dec 7.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11064-010-0351-8DOI Listing
December 2010

Agrin downregulation induced by nerve injury contributes to neuropathic pain.

J Neurosci 2010 Nov;30(45):15286-97

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.4418-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633831PMC
November 2010

Mapping the entire human corneal nerve architecture.

Exp Eye Res 2010 Oct 27;91(4):513-23. Epub 2010 Jul 27.

Neuroscience Center of Excellence and Department of Ophthalmology, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2010.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939211PMC
October 2010

Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1.

J Lipid Res 2010 Aug 9;51(8):2018-31. Epub 2010 Apr 9.

Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, Neuroscience Center of Excellence, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://www.jlr.org/lookup/doi/10.1194/jlr.R001131
Publisher Site
http://dx.doi.org/10.1194/jlr.R001131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903812PMC
August 2010

Inflammatory, apoptotic, and survival gene signaling in Alzheimer's disease. A review on the bioactivity of neuroprotectin D1 and apoptosis.

Mol Neurobiol 2010 Aug 23;42(1):10-6. Epub 2010 Apr 23.

LSU Neuroscience Center of Excellence and Department of Ophthalmology, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite 904, New Orleans, LA 70112-2272, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-010-8126-4DOI Listing
August 2010

PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis.

Exp Eye Res 2010 Jun 15;90(6):718-25. Epub 2010 Mar 15.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2010.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873108PMC
June 2010

Neuroprotectin D1 induces dephosphorylation of Bcl-xL in a PP2A-dependent manner during oxidative stress and promotes retinal pigment epithelial cell survival.

J Biol Chem 2010 Jun 2;285(24):18301-8. Epub 2010 Apr 2.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.095232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881755PMC
June 2010

Omega-3 essential fatty acids modulate initiation and progression of neurodegenerative disease.

Mol Neurobiol 2010 Jun 14;41(2-3):367-74. Epub 2010 May 14.

Diater Laboratorios, 28918, Leganes, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-010-8139-zDOI Listing
June 2010

Docosahexaenoic acid neurolipidomics.

Prostaglandins Other Lipid Mediat 2010 Apr 3;91(3-4):85-9. Epub 2009 Oct 3.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prostaglandins.2009.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905848PMC
April 2010

Lipid-mediated cell signaling protects against injury and neurodegeneration.

J Nutr 2010 Apr 24;140(4):858-63. Epub 2010 Feb 24.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3945/jn.109.114884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838626PMC
April 2010

A novel platelet activating factor receptor antagonist reduces cell infiltration and expression of inflammatory mediators in mice exposed to desiccating conditions after PRK.

Clin Dev Immunol 2009 9;2009:138513. Epub 2009 Dec 9.

LSU Eye Center and Neuroscience Center, LSU Health Sciences Center, School of Medicine, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2009/138513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798082PMC
March 2010

Neuroprotectin D1 attenuates laser-induced choroidal neovascularization in mouse.

Mol Vis 2010 Mar 2;16:320-9. Epub 2010 Mar 2.

Department of Ophthalmology and the Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834569PMC
March 2010

Neuroprotectin D1 synthesis and corneal nerve regeneration after experimental surgery and treatment with PEDF plus DHA.

Invest Ophthalmol Vis Sci 2010 Feb 24;51(2):804-10. Epub 2009 Sep 24.

Department of Ophthalmology and Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.09-3641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868452PMC
February 2010

Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils.

Prostaglandins Leukot Essent Fatty Acids 2010 Jan;82(1):27-34

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, 2020 Gravier Street, Ste. D, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09523278090018
Publisher Site
http://dx.doi.org/10.1016/j.plefa.2009.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822836PMC
January 2010

Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection.

Authors:
Nicolas G Bazan

Prostaglandins Leukot Essent Fatty Acids 2009 Aug-Sep;81(2-3):205-11. Epub 2009 Jun 11.

Neuroscience Center of Excellence and Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite D, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.plefa.2009.05.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756692PMC
November 2009

Robust docosahexaenoic acid-mediated neuroprotection in a rat model of transient, focal cerebral ischemia.

Stroke 2009 Sep 18;40(9):3121-6. Epub 2009 Jun 18.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/STROKEAHA.109.555979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745047PMC
September 2009

Is NF-kappa B from astrocytes a decision maker of neuronal life or death? (Commentary on Dvoriantchikova et al.).

Authors:
Nicolas G Bazan

Eur J Neurosci 2009 Jul 15;30(2):173-4. Epub 2009 Jul 15.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, LA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1460-9568.2009.06853.xDOI Listing
July 2009

Selective survival rescue in 15-lipoxygenase-1-deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1.

J Biol Chem 2009 Jun 29;284(26):17877-82. Epub 2009 Apr 29.

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, Louisiana 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.003988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719426PMC
June 2009

Simplified lentivirus vector production in protein-free media using polyethylenimine-mediated transfection.

J Virol Methods 2009 May 20;157(2):113-21. Epub 2009 Jan 20.

Louisiana State University Health Sciences Center, New Orleans, 70112, USA.

View Article

Download full-text PDF

Source
http://ac.els-cdn.com/S016609340800431X/1-s2.0-S016609340800
Web Search
http://dx.doi.org/10.1016/j.jviromet.2008.11.021DOI Listing
May 2009

Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations, and Alzheimer's disease.

Authors:
Nicolas G Bazan

J Lipid Res 2009 Apr 18;50 Suppl:S400-5. Epub 2008 Nov 18.

Neuroscience Center of Excellence and Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.R800068-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674685PMC
April 2009

LAU-0901, a novel platelet-activating factor receptor antagonist, confers enduring neuroprotection in experimental focal cerebral ischemia in the rat.

Brain Res 2009 Feb 3;1253:184-90. Epub 2008 Dec 3.

Neuroscience Center of Excellence, Louisiana State University Health Science Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2008.11.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637461PMC
February 2009

LAU-0901, a novel platelet-activating factor antagonist, is highly neuroprotective in cerebral ischemia.

Exp Neurol 2008 Dec 28;214(2):253-8. Epub 2008 Aug 28.

Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2008.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647717PMC
December 2008

Docosahexaenoic acid and the aging brain.

J Nutr 2008 Dec;138(12):2510-4

Department of Ophthalmology, LSU Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3945/jn.108.096016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666388PMC
December 2008

A comparative analysis of constitutive and cell-specific promoters in the adult mouse hippocampus using lentivirus vector-mediated gene transfer.

J Gene Med 2008 Nov;10(11):1163-75

Gene Therapy Program, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jgm.1249
Publisher Site
http://dx.doi.org/10.1002/jgm.1249DOI Listing
November 2008

Neurotrophins induce neuroprotective signaling in the retinal pigment epithelial cell by activating the synthesis of the anti-inflammatory and anti-apoptotic neuroprotectin D1.

Authors:
Nicolas G Bazan

Adv Exp Med Biol 2008 ;613:39-44

Louisiana State University Health Sciences Center, Neuroscience Center of Excellence and Department of Ophthalmology, 2020 Gravier Street, Suite D, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645073PMC
http://dx.doi.org/10.1007/978-0-387-74904-4_3DOI Listing
February 2008

Homeostatic regulation of photoreceptor cell integrity: significance of the potent mediator neuroprotectin D1 biosynthesized from docosahexaenoic acid: the Proctor Lecture.

Authors:
Nicolas G Bazan

Invest Ophthalmol Vis Sci 2007 Nov;48(11):4866-81; biography 4864-5

Neuroscience Center of Excellence and Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

View Article

Download full-text PDF

Source
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
Publisher Site
http://dx.doi.org/10.1167/iovs.07-0918DOI Listing
November 2007

Platelet activating factor-induced neuronal apoptosis is initiated independently of its G-protein coupled PAF receptor and is inhibited by the benzoate orsellinic acid.

J Neurochem 2007 Oct;103(1):88-97

Department of Biochemistry, Microbiology, and Immunology, Neural Regeneration Laboratory and Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1471-4159.2007.04740.xDOI Listing
October 2007