Nicolas Coquelle

Nicolas Coquelle

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Nicolas Coquelle

Nicolas Coquelle

Publications by authors named "Nicolas Coquelle"

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Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures.

Proc Natl Acad Sci U S A 2020 Feb 11;117(8):4142-4151. Epub 2020 Feb 11.

Université Grenoble Alpes, Commissariat à l'Énergie Atomique et aux Énergies Alternatives (CEA), CNRS, Institut de Biologie Structurale (IBS), F-38000 Grenoble, France;

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http://dx.doi.org/10.1073/pnas.1821522117DOI Listing
February 2020

Perdeuteration, large crystal growth and neutron data collection of Leishmania mexicana triose-phosphate isomerase E65Q variant.

Acta Crystallogr F Struct Biol Commun 2019 Apr 2;75(Pt 4):260-269. Epub 2019 Apr 2.

Department of Biology, Lund University, Sölvegatan 35, 223 62 Lund, Sweden.

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http://dx.doi.org/10.1107/S2053230X19001882DOI Listing
April 2019

Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis.

Molecules 2018 Mar 11;23(3). Epub 2018 Mar 11.

Laboratory of Pharmaceutical Chemistry (CSIC Associated Unit), Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII 27-31, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.3390/molecules23030634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017698PMC
March 2018

N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.

Bioorg Med Chem 2017 01 19;25(2):633-645. Epub 2016 Nov 19.

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.11.032DOI Listing
January 2017

Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents.

Bioorg Med Chem 2015 Aug 14;23(15):4442-52. Epub 2015 Jun 14.

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.06.010DOI Listing
August 2015

Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.

J Med Chem 2014 Oct 29;57(19):8167-79. Epub 2014 Sep 29.

Faculty of Pharmacy, University of Ljubljana , Aškerčeva 7, 1000 Ljubljana, Slovenia.

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http://dx.doi.org/10.1021/jm501195eDOI Listing
October 2014

An experimental point of view on hydration/solvation in halophilic proteins.

Front Microbiol 2014 21;5:66. Epub 2014 Feb 21.

Institut de Biologie Structurale, Université Grenoble Alpes Grenoble, France ; CEA, DSV, Institut de Biologie Structurale Grenoble, France ; Institut de Biologie Structurale, Centre National de la Recherche Scientifique Grenoble, France.

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http://dx.doi.org/10.3389/fmicb.2014.00066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930881PMC
March 2014

An ER-peroxisome tether exerts peroxisome population control in yeast.

EMBO J 2013 Sep 30;32(18):2439-53. Epub 2013 Jul 30.

Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1038/emboj.2013.170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770948PMC
September 2013

Domain swapping in the cytoplasmic domain of the Escherichia coli rhomboid protease.

J Mol Biol 2013 Apr 23;425(7):1127-42. Epub 2013 Jan 23.

Membrane Protein Disease Research Group, Department of Biochemistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada T6G 2H7.

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http://dx.doi.org/10.1016/j.jmb.2013.01.019DOI Listing
April 2013

PARP pairs up to PARsylate.

Nat Struct Mol Biol 2012 Jul 5;19(7):660-1. Epub 2012 Jul 5.

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http://dx.doi.org/10.1038/nsmb.2306DOI Listing
July 2012

Sampling the conformational energy landscape of a hyperthermophilic protein by engineering key substitutions.

Mol Biol Evol 2012 Jun 19;29(6):1683-94. Epub 2012 Jan 19.

Dynamop Group, Institut de Biologie Structurale J.-P. Ebel, CEA CNRS UJF, UMR 5075, Grenoble cedex 01, France.

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http://dx.doi.org/10.1093/molbev/mss015DOI Listing
June 2012

Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.

Proc Natl Acad Sci U S A 2011 Dec 14;108(52):21022-7. Epub 2011 Dec 14.

Department of Biochemistry, University of Alberta, Edmonton, AB, Canada T6G 2H7.

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http://dx.doi.org/10.1073/pnas.1112036108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248541PMC
December 2011

Impact of BRCA1 BRCT domain missense substitutions on phosphopeptide recognition.

Biochemistry 2011 May 10;50(21):4579-89. Epub 2011 May 10.

Department of Biochemistry, School of Medicine, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1021/bi2003795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100782PMC
May 2011

Gradual adaptive changes of a protein facing high salt concentrations.

J Mol Biol 2010 Dec 1;404(3):493-505. Epub 2010 Oct 1.

IBS, Institut de Biologie Structurale Jean-Pierre Ébel, Extremophilic and Large Molecular Assemblies Team, UMR 5075, CEA, CNRS, Université Joseph Fourier, 41 rue Jules Horowitz, F-38027 Grenoble, France.

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http://dx.doi.org/10.1016/j.jmb.2010.09.055DOI Listing
December 2010

FHA domain pThr binding specificity: it's all about me.

Structure 2010 Dec;18(12):1549-50

Department of Biochemistry, School of Molecular and Systems Medicine, University of Alberta, Edmonton, AB T6G2H7, Canada.

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http://dx.doi.org/10.1016/j.str.2010.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881964PMC
December 2010

Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments.

J Mol Biol 2007 Nov 22;374(2):547-62. Epub 2007 Sep 22.

Laboratoire de Biophysique Moléculaire, Institut de Biologie Structurale J.-P. Ebel, CEA CNRS UJF, UMR 5075, 41 rue Jules Horowitz, 38027 Grenoble Cedex 01, France.

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http://dx.doi.org/10.1016/j.jmb.2007.09.049DOI Listing
November 2007