Publications by authors named "Nicolas Cagnard"

69Publications

IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment.

J Immunother Cancer 2020 06;8(1)

Analyse Moléculaire, Modélisation et Imagerie de la Maladie Cancéreuse, Laboratoire d'Immunomonitoring en Oncologie, Gustave Roussy Institute, INSERM, CNRS, Paris-Saclay University, Villejuif, Île-de-France, France

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http://dx.doi.org/10.1136/jitc-2020-000632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295443PMC
June 2020

MeCP2 is involved in random mono-allelic expression for a subset of human autosomal genes.

Biochim Biophys Acta Mol Basis Dis 2020 06 15;1866(6):165730. Epub 2020 Feb 15.

Assistance Publique - Hôpitaux de Paris, APHP, Centre Universitaire Paris, Hôpital Cochin, Laboratoire de Génétique et Biologie Moléculaires, Paris, France; Institut de Psychiatrie et de Neurosciences de Paris (IPNP), INSERM U1266, Team "Vulnérabilité aux troubles psychiatriques et addictifs", Université de Paris, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2020.165730DOI Listing
June 2020

Congenital cystic adenomatoid malformations of the lung: an epithelial transcriptomic approach.

Respir Res 2020 Feb 4;21(1):43. Epub 2020 Feb 4.

Service de Pneumologie et d'Allergologie Pédiatriques, AP-HP, Hôpital Universitaire Necker-Enfants Malades, 75743 Cedex 15, Paris, France.

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http://dx.doi.org/10.1186/s12931-020-1306-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001206PMC
February 2020

CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia.

Cell Rep 2020 01;30(2):299-307.e3

Université Paris Descartes Sorbonne Cité, Institut Necker Enfants Malades (INEM), Institut National de Recherche Médicale (INSERM) U1151, Paris, France; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker-Enfants Malades, Paris, France; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland; National Children's Research Centre, Children's Health Ireland at Crumlin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.12.026DOI Listing
January 2020

Ttc7a regulates hematopoietic stem cell functions while controlling the stress-induced response.

Haematologica 2020 01 19;105(1):59-70. Epub 2019 Apr 19.

Laboratory of Normal and Pathological Homeostasis of the Immune System, INSERM UMR 1163, Imagine Institute, Paris

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.207100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939534PMC
January 2020

Role of in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders.

Mol Autism 2018 19;9:38. Epub 2018 Jun 19.

1INSERM UMR 1163, Laboratory of Molecular and pathophysiological bases of cognitive disorders, Imagine Institute, Necker-Enfants Malades Hospital, 24 Boulevard du Montparnasse, 75015 Paris, France.

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http://dx.doi.org/10.1186/s13229-018-0219-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011198PMC
October 2018

BAFF and CD4 T cells are major survival factors for long-lived splenic plasma cells in a B-cell-depletion context.

Blood 2018 04 29;131(14):1545-1555. Epub 2018 Jan 29.

Institut Necker-Enfants Malades-INSERM U1151/Centre National de la Recherche (CNRS) UMR8633, Université Paris Descartes, Faculté de Médecine, Paris, France.

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http://dx.doi.org/10.1182/blood-2017-06-789578DOI Listing
April 2018

Generation of adult human T-cell progenitors for immunotherapeutic applications.

J Allergy Clin Immunol 2018 04 5;141(4):1491-1494.e4. Epub 2017 Dec 5.

Human Lymphohaematopoiesis Laboratory, INSERM U1163, Paris, France; University of Paris Descartes-Sorbonne Paris Cité, IMAGINE Institute, Paris, France; Biotherapy Clinical Investigation Centre, Necker Children's Hospital, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.10.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887055PMC
April 2018

Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation.

J Immunol 2017 10 14;199(7):2408-2420. Epub 2017 Aug 14.

Équipe Développement du Systéme Immunitaire, Institut Necker-Enfant Malades, INSERM U1151-CNRS UMR8253, Faculté de Médecine Paris Decartes, Université Paris Descartes, Sorbone Paris Cité, 75993 Paris Cedex 14, France;

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http://dx.doi.org/10.4049/jimmunol.1700708DOI Listing
October 2017

Atorvastatin reduces β-Adrenergic dysfunction in rats with diabetic cardiomyopathy.

PLoS One 2017 20;12(7):e0180103. Epub 2017 Jul 20.

Sorbonne Universités, UPMC Univ Paris 06, UMR INSERM 1166, IHU ICAN, and Department of Anesthesiology and Critical Care Medicine, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180103PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519044PMC
September 2017

A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours.

J Pathol 2017 09 28;243(1):51-64. Epub 2017 Jul 28.

Institut Necker Enfants Malades (INEM), Inserm U1151-CNRS UMR 8253, University Paris Descartes, Sorbonne Paris Cité, Faculty of Medicine, Paris, France.

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http://dx.doi.org/10.1002/path.4924DOI Listing
September 2017

Regulatory T cells delay disease progression in Alzheimer-like pathology.

Brain 2016 Apr 1;139(Pt 4):1237-51. Epub 2016 Feb 1.

1 INSERM, UMRS 938, CdR Saint-Antoine, Laboratory Immune System, Neuroinflammation and Neurodegenerative Diseases, Hôpital St-Antoine, F-75012, Paris, France 2 Sorbonne Universités, UPMC Univ Paris 06, UMRS 938, CdR Saint-Antoine, Hôpital Saint-Antoine, F-75012, Paris, France.

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http://dx.doi.org/10.1093/brain/awv408DOI Listing
April 2016

Synergy of chemotherapy and immunotherapy revealed by a genome-scale analysis of murine tuberculosis.

J Antimicrob Chemother 2015 16;70(6):1774-83. Epub 2015 Feb 16.

The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil.

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http://dx.doi.org/10.1093/jac/dkv023DOI Listing
February 2016

Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulation.

J Immunol 2015 Mar 2;194(5):2117-27. Epub 2015 Feb 2.

San Raffaele Diabetes Research Institute, San Raffaele Scientific Institute, 20132 Milan, Italy; TrialNet Clinical Center, San Raffaele Hospital, 20132 Milan, Italy

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http://dx.doi.org/10.4049/jimmunol.1401551DOI Listing
March 2015

Metabolic and adipose tissue signatures in adults with Prader-Willi syndrome: a model of extreme adiposity.

J Clin Endocrinol Metab 2015 Mar 5;100(3):850-9. Epub 2014 Dec 5.

INSERM, U1166, Nutriomic team 6 (D.L., H.H., V.P., C.R., B.D., K.C., C.P.), Sorbonne Universities (D.L., H.H., V.P., C.R., B.D., K.C., C.P.), University Pierre et Marie Curie-Paris 6, Unité Mixte de Recherche en Santé Unité 1166, and Institute of Cardiometabolism and Nutrition (ICAN) (S.M., M.C., P.F., K.C., C.P.), Assistance Publique Hôpitaux de Paris, Department of Nutrition, and French Reference Centre for Prader-Willi Syndrome, Pitié-Salpêtrière Hospital, Paris, F-75013 France; Functional Unit of Inflammatory and Metabolic Biomarkers (J.-P.B.), Department of Biochemistry and Hormonology, Tenon Hospital, Assistance Publique des Hôpitaux de Paris, F-75970 Paris, France; Bioinformatics Platform (N.C.), Plateforme de Bioinformatique, SFR Necker, University Paris V, F-75015 Paris, France; and Department of Pediatric Nutrition and Gastroenterology (B.D.), Trousseau Hospital, Assistance Publique Hôpitaux de Paris, F-37044 Paris, France.

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http://dx.doi.org/10.1210/jc.2014-3127DOI Listing
March 2015

Reverse interferon signature is characteristic of antigen-presenting cells in human and rat spondyloarthritis.

Arthritis Rheumatol 2014 Apr;66(4):841-51

Université Paris-Descartes, Sorbonne Paris Cité, Laboratoire d'Excellence Inflamex, Institut Cochin, and INSERM U1016, CNRS (UMR 8104), Paris, France.

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http://dx.doi.org/10.1002/art.38318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226235PMC
April 2014

Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells.

Front Immunol 2013 4;4:19. Epub 2013 Feb 4.

Centre de Recherche des Cordeliers, INSERM, U872 Paris, France ; Université Pierre et Marie Curie Paris, France ; Université Paris Descartes Paris, France.

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http://dx.doi.org/10.3389/fimmu.2013.00019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563113PMC
February 2013

Translation termination efficiency modulates ATF4 response by regulating ATF4 mRNA translation at 5' short ORFs.

Nucleic Acids Res 2012 Oct 16;40(19):9557-70. Epub 2012 Aug 16.

UPMC Univ Paris 06, CNRS-FRE 3402, Biologie de l'ARN, 9 quai Saint Bernard, 75005 Paris, France.

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http://dx.doi.org/10.1093/nar/gks762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479206PMC
October 2012

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).

Proc Natl Acad Sci U S A 2012 Jun 14;109(23):8965-70. Epub 2012 May 14.

Institut Cochin, Department of Endocrinology, Metabolism and Cancer, Université Paris Descartes, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, 75014 Paris, France.

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http://dx.doi.org/10.1073/pnas.1201652109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384132PMC
June 2012

A lineage of myeloid cells independent of Myb and hematopoietic stem cells.

Science 2012 Apr 22;336(6077):86-90. Epub 2012 Mar 22.

Centre for Molecular and Cellular Biology of Inflammation, New Hunt's House, King's College London, Great Maze Pond, London SE1 1UL, UK.

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http://dx.doi.org/10.1126/science.1219179DOI Listing
April 2012

Insights into the pathogenesis of systemic sclerosis based on the gene expression profile of progenitor-derived endothelial cells.

Arthritis Rheum 2011 Nov;63(11):3552-62

Université Paris Descartes and Hôpital Cochin, AP-HP, and INSERM U1016, Cochin Institut, Paris, France.

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http://dx.doi.org/10.1002/art.30536DOI Listing
November 2011

Critical role of cRel subunit of NF-κB in sepsis survival.

Infect Immun 2011 May 22;79(5):1848-54. Epub 2011 Feb 22.

Département de Biologie Cellulaire des Interactions Hôte-Pathogène, Institut Cochin, Paris, France.

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http://dx.doi.org/10.1128/IAI.00021-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088128PMC
May 2011

Gene expression profile in the salivary glands of primary Sjögren's syndrome patients before and after treatment with rituximab.

Arthritis Rheum 2010 Aug;62(8):2262-71

Hôpital de la Cavale Blanche, Centre Hospitalier Universitaire Brest, and Hôpital Morvan, Brest, France.

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http://dx.doi.org/10.1002/art.27509DOI Listing
August 2010

FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase.

J Immunol 2008 Sep;181(5):2980-9

Institut Cochin, Université Paris Descartes, Centre National de la Recherche Scientifique (Unité Mixte de Recherche 8104), Equipe labellisée par la Ligue Nationale contre le Cancer, Paris, France.

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http://dx.doi.org/10.4049/jimmunol.181.5.2980DOI Listing
September 2008

CTLA-4 +49A/G and CT60 gene polymorphisms in primary Sjögren syndrome.

Arthritis Res Ther 2007 ;9(2):R24

Rhumatologie, Institut Pour la Santé et la Recherche Médicale U802, Université Paris-Sud 11, Hôpital Bicêtre, 78 rue du Général Leclerc, Assistance Publique-Hôpitaux de Paris, 94275 Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1186/ar2136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906800PMC
November 2007

Failure to confirm coxsackievirus infection in primary Sjögren's syndrome.

Arthritis Rheum 2006 Jun;54(6):2026-8

Hôpital de Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1002/art.21906DOI Listing
June 2006

Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome.

Proc Natl Acad Sci U S A 2006 Feb 13;103(8):2770-5. Epub 2006 Feb 13.

Institut Pour la Santé et de la Recherche Médicale E 802 and Service de Rhumatologie, Hôpital de Bicêtre, Assistance Publique-Hôpitaux de Paris, 94275 Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1073/pnas.0510837103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413808PMC
February 2006

Interleukin-32, CCL2, PF4F1 and GFD10 are the only cytokine/chemokine genes differentially expressed by in vitro cultured rheumatoid and osteoarthritis fibroblast-like synoviocytes.

Eur Cytokine Netw 2005 Dec;16(4):289-92

Institut Cochin, Département d'Immunologie, Hôpital Cochin, Pavillon Hardy A, 27 rue du Faubourg Saint-Jacques, 75674 Paris Cedex 14, France.

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December 2005