Nicolas A Dumont

Nicolas A Dumont

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Nicolas A Dumont

Nicolas A Dumont

Publications by authors named "Nicolas A Dumont"

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Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases.

Stem Cells Int 2019 14;2019:4761427. Epub 2019 Jul 14.

CHU Sainte-Justine Research Center, Montreal, QC, Canada.

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http://dx.doi.org/10.1155/2019/4761427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664695PMC
July 2019

EGFR-Aurka Signaling Rescues Polarity and Regeneration Defects in Dystrophin-Deficient Muscle Stem Cells by Increasing Asymmetric Divisions.

Cell Stem Cell 2019 03 31;24(3):419-432.e6. Epub 2019 Jan 31.

Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Regenerative Medicine Program, Ottawa, ON, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; Department of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408300PMC
March 2019

Characterizing Satellite Cells and Myogenic Progenitors During Skeletal Muscle Regeneration.

Methods Mol Biol 2017 ;1560:179-188

Centre for Stem Cell Research, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, Canada, K1H 8L6.

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http://dx.doi.org/10.1007/978-1-4939-6788-9_12DOI Listing
February 2018

Impact of Inflammation and Anti-inflammatory Modalities on Skeletal Muscle Healing: From Fundamental Research to the Clinic.

Phys Ther 2017 Aug;97(8):807-817

Musculoskeletal Diseases and Rehabilitation Department, Ste-Justine Hospital Research Center, Montreal, Quebec, Canada; and Department of Rehabilitation, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1093/ptj/pzx056DOI Listing
August 2017

[Inflammation and muscle regeneration, a double-edged sword].

Med Sci (Paris) 2016 Jun-Jul;32(6-7):591-7. Epub 2016 Jul 12.

Centre de recherche du Centre Hospitalier Universitaire Ste-Justine. Montréal, QC, Canada - École de réadaptation, Faculté de Médecine, Université de Montréal, 7077 avenue du Parc Montréal, H3N 1X7 Montréal QC, Canada.

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http://dx.doi.org/10.1051/medsci/20163206022DOI Listing
July 2017

[Cell-autonomous defects in satellite cells impair muscle regeneration in Duchenne muscular dystrophy].

Med Sci (Paris) 2016 Oct 19;32(10):800-802. Epub 2016 Oct 19.

Centre de recherche du centre hospitalier universitaire Ste-Justine, Montréal, Québec, Canada - École de réadaptation, faculté de médecine, Université de Montréal, 7077 avenue du Parc, H3N 1X7 Montréal, Québec, Canada.

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http://dx.doi.org/10.1051/medsci/20163210003DOI Listing
October 2016

Targeting muscle stem cell intrinsic defects to treat Duchenne muscular dystrophy.

NPJ Regen Med 2016 9;1. Epub 2016 Jun 9.

Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Regenerative Medicine Program, Ottawa, ON, Canada.

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http://dx.doi.org/10.1038/npjregenmed.2016.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703417PMC
June 2016

Muscle RANK is a key regulator of Ca2+ storage, SERCA activity, and function of fast-twitch skeletal muscles.

Am J Physiol Cell Physiol 2016 04 28;310(8):C663-72. Epub 2016 Jan 28.

Centre Hospitalier Universitaire de Québec-Centre de Recherche du Centre Hospitalier de l'Université Laval, Université Laval, Quebec City, Quebec, Canada; Faculté de Médecine, Département de Réadaptation, Université Laval, Quebec City, Quebec, Canada

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http://dx.doi.org/10.1152/ajpcell.00285.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835920PMC
April 2016

Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division.

Nat Med 2015 Dec 16;21(12):1455-63. Epub 2015 Nov 16.

Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Regenerative Medicine Program, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1038/nm.3990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839960PMC
December 2015

Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells.

Proc Natl Acad Sci U S A 2015 Sep 8;112(38):E5246-52. Epub 2015 Sep 8.

Regenerative Medicine Program, Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, ON, Canada K1H 8L6; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada K1H 8L6; Department of Medicine, University of Ottawa, Ottawa, ON, Canada K1H 8L6

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http://dx.doi.org/10.1073/pnas.1512869112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586827PMC
September 2015

Satellite Cells and Skeletal Muscle Regeneration.

Compr Physiol 2015 Jul;5(3):1027-59

Sprott Centre for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1002/cphy.c140068DOI Listing
July 2015

Intrinsic and extrinsic mechanisms regulating satellite cell function.

Development 2015 May;142(9):1572-81

Sprott Centre for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada K1H 8L6 Faculty of Medicine, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5

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http://dx.doi.org/10.1242/dev.114223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419274PMC
May 2015

Osteoprotegerin protects against muscular dystrophy.

Am J Pathol 2015 Apr 21;185(4):920-6. Epub 2015 Feb 21.

CHU (CHUL) Research Center of Quebec, Université Laval, Quebec City, Quebec, Canada; Department of Rehabilitation, Faculty of Medicine, Université Laval, Quebec City, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.01.006DOI Listing
April 2015

Muscle stem cells at a glance.

J Cell Sci 2014 Nov 9;127(Pt 21):4543-8. Epub 2014 Oct 9.

Sprott Centre for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada Faculty of Medicine, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada

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http://dx.doi.org/10.1242/jcs.151209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215708PMC
November 2014

Inhibition of JAK-STAT signaling stimulates adult satellite cell function.

Nat Med 2014 Oct 7;20(10):1174-81. Epub 2014 Sep 7.

1] Sprott Center For Stem Cell Research, Ottawa Hospital Research Institute, Regenerative Medicine Program, Ottawa, Ontario, Canada. [2] Department of Cellular and Molecular Medicine, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1038/nm.3655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191983PMC
October 2014

Cellular dynamics in the muscle satellite cell niche.

EMBO Rep 2013 Dec 15;14(12):1062-72. Epub 2013 Nov 15.

Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada.

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http://embor.embopress.org/cgi/doi/10.1038/embor.2013.182
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849491PMC
http://dx.doi.org/10.1038/embor.2013.182DOI Listing
December 2013

Macrophage colony-stimulating factor-induced macrophage differentiation promotes regrowth in atrophied skeletal muscles and C2C12 myotubes.

Am J Pathol 2013 Feb 27;182(2):505-15. Epub 2012 Nov 27.

Centre de Recherche du CHU de Québec CHUL, Université Laval, Quebec City, Quebec, Canada.

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http://dx.doi.org/10.1016/j.ajpath.2012.10.010DOI Listing
February 2013