Nicola Zanesi

Nicola Zanesi

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Nicola Zanesi

Nicola Zanesi

Publications by authors named "Nicola Zanesi"

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63Publications

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miR-130a Deregulates PTEN and Stimulates Tumor Growth.

Cancer Res 2017 11 21;77(22):6168-6178. Epub 2017 Sep 21.

Department of Cancer Biology and Genetics, and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0530DOI Listing
November 2017

Selective targeting of point-mutated KRAS through artificial microRNAs.

Proc Natl Acad Sci U S A 2017 05 8;114(21):E4203-E4212. Epub 2017 May 8.

Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210;

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http://dx.doi.org/10.1073/pnas.1620562114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448175PMC
May 2017

A novel fully human anti-NCL immunoRNase for triple-negative breast cancer therapy.

Oncotarget 2016 Dec;7(52):87016-87030

Department of Molecular Medicine and Medical Biotechnology, University of Naples "Federico II", 80131 Naples, Italy.

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http://www.oncotarget.com/fulltext/13522
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http://dx.doi.org/10.18632/oncotarget.13522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349967PMC
December 2016

Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation.

Cancer Med 2016 08 17;5(8):2032-42. Epub 2016 May 17.

Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

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http://dx.doi.org/10.1002/cam4.768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873604PMC
August 2016

Pluripotent stem cell miRNAs and metastasis in invasive breast cancer.

J Natl Cancer Inst 2014 Dec 11;106(12). Epub 2014 Oct 11.

Department of Molecular Virology, Immunology and Molecular Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH (SV, GN, AD, SC, MiG, RAe, RG, GDL, PG, PD, TW, SEW, FP, NZ, HA, KFH, CMC); Biosystems Analysis, LTTA, Deptartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy, (SV, MES, JM, MaG, MM, CZ, FC, MP, JP, MN); Fate Therapeutics, San Diego, CA (RAb); Department of Chemistry, The Scripps Research Institute, La Jolla, CA (CD); Department of Urology, Thomas Jefferson University, Kimmel Cancer Center, Philadelphia, PA (RB); Comprehensive Cancer Center, The Ohio State University, Columbus, OH (KM); Deptartment of Internal Medicine, James Cancer Hospital and Ohio State University Comprehensive Cancer Center, The Ohio State University (CLS); Division of Pathology, II University of Rome "La Sapienza," Ospedale Santo Andrea, Rome, Italy (AV); Department of Surgery, Thomas Jefferson University Medical College, Philadelphia, PA (ALR).

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http://dx.doi.org/10.1093/jnci/dju324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334797PMC
December 2014

Fhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel.

PLoS One 2013 6;8(11):e78610. Epub 2013 Nov 6.

Department of Molecular Immunology, Virology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America ; Lymphoma and Genomics Research Program, IOR Institute of Oncology Research, Bellinzona, Switzerland ; Dipartimento di Medicina Sperimentale e Clinica, University Magna Græcia, Campus "S. Venuta", Catanzaro, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078610PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819369PMC
August 2014

Toll-like receptor 3 (TLR3) activation induces microRNA-dependent reexpression of functional RARβ and tumor regression.

Proc Natl Acad Sci U S A 2013 Jun 28;110(24):9812-7. Epub 2013 May 28.

Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, DAHFMO, Unit of Histology and Medical Embryology, Istituto Pasteur-Fondazione Cenci Bolognetti, La Sapienza University of Rome, 00161 Rome, Italy.

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http://dx.doi.org/10.1073/pnas.1304610110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683754PMC
June 2013

A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model.

Blood 2013 May 16;121(21):4355-8. Epub 2013 Apr 16.

Department of Molecular Virology, Immunology and Medical Genetics and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1182/blood-2013-02-486035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663428PMC
May 2013

Novel insights in molecular mechanisms of CLL.

Curr Pharm Des 2012 ;18(23):3363-72

Human Cancer Genetics Program and Department of Molecular Virology, Immunology and Medical Genetics, OSU School of Medicine, Ohio State University, Columbus, USA.

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http://dx.doi.org/10.2174/138161212801227104DOI Listing
December 2012

Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL).

Proc Natl Acad Sci U S A 2012 Feb 30;109(7):2555-60. Epub 2012 Jan 30.

Human Cancer Genetics Program and Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University School of Medicine, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.1200003109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289317PMC
February 2012

Common fragile site tumor suppressor genes and corresponding mouse models of cancer.

J Biomed Biotechnol 2011 29;2011:984505. Epub 2010 Dec 29.

Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1155/2011/984505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035048PMC
June 2011

Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.

Carcinogenesis 2011 Mar 19;32(3):351-8. Epub 2010 Nov 19.

Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1093/carcin/bgq251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047237PMC
March 2011

Molecular basis of CLL.

Semin Cancer Biol 2010 Dec 21;20(6):370-6. Epub 2010 Sep 21.

Human Cancer Genetics Program and Department of Molecular Virology, Immunology and Medical Genetics, OSU School of Medicine, Ohio State University, Columbus, OH 43210, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X100008
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http://dx.doi.org/10.1016/j.semcancer.2010.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997849PMC
December 2010

Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression.

Proc Natl Acad Sci U S A 2010 Jul 21;107(27):12210-5. Epub 2010 Jun 21.

Department of Molecular Virology, Ohio State University School of Medicine, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.1007186107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901490PMC
July 2010

Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor.

Urol Oncol 2010 Mar-Apr;28(2):189-94. Epub 2009 Apr 16.

Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.urolonc.2009.01.016DOI Listing
June 2010

Oncosuppressor proteins of fragile sites are reduced in cervical cancer.

Cancer Lett 2010 Mar 22;289(1):40-5. Epub 2009 Aug 22.

Cytopathology, II Faculty of Medicine, University of Rome La Sapienza, Sant'Andrea Hospital, Rome, Italy.

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http://dx.doi.org/10.1016/j.canlet.2009.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987609PMC
March 2010

MicroRNAs in mouse models of lymphoid malignancies.

J Nucleic Acids Investig 2010 ;1(1):36-40

Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University, Columbus, OH.

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http://dx.doi.org/10.4081/jnai.2010.e8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111058PMC
January 2010

MicroRNA 29b functions in acute myeloid leukemia.

Blood 2009 Dec 22;114(26):5331-41. Epub 2009 Oct 22.

Division of Hematology and Oncology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1182/blood-2009-03-211938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796138PMC
December 2009

MiR-15a and miR-16-1 cluster functions in human leukemia.

Proc Natl Acad Sci U S A 2008 Apr 24;105(13):5166-71. Epub 2008 Mar 24.

Human Cancer Genetics Program and Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.0800121105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278188PMC
April 2008

Animal models for chronic lymphocytic leukemia.

J Cell Biochem 2007 Apr;100(5):1109-18

Comprehensive Cancer Center, Human Cancer Genetics Program, Department of Molecular Virology, Immunology and Medical Genetics, OSU School of Medicine, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1002/jcb.21147DOI Listing
April 2007

Targeted deletion of Wwox reveals a tumor suppressor function.

Proc Natl Acad Sci U S A 2007 Mar 27;104(10):3949-54. Epub 2007 Feb 27.

Department of Molecular Virology, Immunology, and Medical Genetics, Comprehensive Cancer Center, Ohio State University, 410 West 12th Avenue, Columbus, OH 43210, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0609783104
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http://dx.doi.org/10.1073/pnas.0609783104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820689PMC
March 2007

Molecular and cytogenetical alterations induced by environmental cigarette smoke in mice heterozygous for Fhit.

Cancer Res 2007 Feb;67(3):1001-6

Department of Health Sciences, University of Genoa, via A. Pastore 1, I-16132 Genoa, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3882DOI Listing
February 2007

FHIT-proteasome degradation caused by mitogenic stimulation of the EGF receptor family in cancer cells.

Proc Natl Acad Sci U S A 2006 Dec 1;103(50):18981-6. Epub 2006 Dec 1.

Molecular Biology Unit, Department of Experimental Oncology, Istituto Nazionale Tumori, via Venezian 1, 20133 Milan, Italy.

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http://dx.doi.org/10.1073/pnas.0605821103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679754PMC
December 2006

Tal1 transgenic expression reveals absence of B lymphocytes.

Cancer Res 2006 Jun;66(12):6014-7

Comprehensive Cancer Center, Human Cancer Genetics Program, OSU School of Medicine, Ohio State University, Columbus, Ohio 43210, USA.

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http://cancerres.aacrjournals.org/content/66/12/6014.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-06-0937DOI Listing
June 2006

Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.

Proc Natl Acad Sci U S A 2006 May 25;103(18):7024-9. Epub 2006 Apr 25.

Comprehensive Cancer Center, Ohio State University, 400 West 12th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.0602266103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459012PMC
May 2006

Early loss of Fhit in the respiratory tract of rodents exposed to environmental cigarette smoke.

Cancer Res 2006 Apr;66(7):3936-41

Department of Health Sciences, University of Genoa, Via A. Pastore 1, I-16132 Genoa, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-3666DOI Listing
April 2006

A mouse model of the fragile gene FHIT: From carcinogenesis to gene therapy and cancer prevention.

Mutat Res 2005 Dec 8;591(1-2):103-9. Epub 2005 Aug 8.

Comprehensive Cancer Center, Ohio State University, 400 W. 12th Avenue, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.mrfmmm.2005.05.016DOI Listing
December 2005

WWOX gene restoration prevents lung cancer growth in vitro and in vivo.

Proc Natl Acad Sci U S A 2005 10 13;102(43):15611-6. Epub 2005 Oct 13.

Department of Molecular Virology, Immunology, and Medical Genetics, Comprehensive Cancer Center, Ohio State University, 410 West 12th Avenue, Columbus, OH 43201, USA.

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http://dx.doi.org/10.1073/pnas.0505485102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266103PMC
October 2005

Knockout mice reveal a tumor suppressor function for Testin.

Proc Natl Acad Sci U S A 2005 Aug 20;102(31):10947-51. Epub 2005 Jul 20.

Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.0504934102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182460PMC
August 2005

Inactivation of the FHIT gene favors bladder cancer development.

Clin Cancer Res 2004 Nov;10(22):7607-12

Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-0341DOI Listing
November 2004

Tcl1 as a model for lymphomagenesis.

Hematol Oncol Clin North Am 2004 Aug;18(4):863-79, ix

Kimmel Cancer Center, Thomas Jefferson University, 233 South 10th Street, BLSB 1050, Philadelphia, PA 19107, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S088985880400041
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http://dx.doi.org/10.1016/j.hoc.2004.04.007DOI Listing
August 2004

Fhit is a physiological target of the protein kinase Src.

Proc Natl Acad Sci U S A 2004 Mar 8;101(11):3775-9. Epub 2004 Mar 8.

Kimmel Cancer Center, Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1073/pnas.0400481101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC374320PMC
March 2004

Cancer prevention and therapy in a preclinical mouse model: impact of FHIT viruses.

Curr Gene Ther 2004 Mar;4(1):53-63

Center for Molecular Medicine, Jichi Medical School, Tochigi 329-0498, Japan.

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http://dx.doi.org/10.2174/1566523044578031DOI Listing
March 2004

Regression of upper gastric cancer in mice by FHIT gene delivery.

FASEB J 2003 Sep 3;17(12):1768-70. Epub 2003 Jul 3.

Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1096/fj.03-0241fjeDOI Listing
September 2003

HMGA2 locus rearrangement in a case of acute lymphoblastic leukemia.

Int J Oncol 2003 Aug;23(2):363-7

Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli Federico II, 80131 Naples, Italy.

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August 2003

FHIT: from gene discovery to cancer treatment and prevention.

Lancet Oncol 2002 Dec;3(12):748-54

Kimmel Cancer Center, Thomas Jefferson University, PA 19107, USA.

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http://dx.doi.org/10.1016/s1470-2045(02)00931-2DOI Listing
December 2002