Publications by authors named "Nicola Strenzke"

41Publications

A role of oligodendrocytes in information processing.

Nat Commun 2020 10 30;11(1):5497. Epub 2020 Oct 30.

Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

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http://dx.doi.org/10.1038/s41467-020-19152-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599337PMC
October 2020

The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea.

Cell Rep 2018 08;24(9):2418-2431.e6

Institute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743 Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.07.087DOI Listing
August 2018

A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics.

Nat Commun 2017 02 21;8:14530. Epub 2017 Feb 21.

Sensory Neuroscience Research Group, School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton BN2 4GJ, UK.

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http://dx.doi.org/10.1038/ncomms14530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321796PMC
February 2017

Ca-binding protein 2 inhibits Ca-channel inactivation in mouse inner hair cells.

Proc Natl Acad Sci U S A 2017 02 9;114(9):E1717-E1726. Epub 2017 Feb 9.

Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Goettingen, 37099 Goettingen, Germany;

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http://dx.doi.org/10.1073/pnas.1617533114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338518PMC
February 2017

Hair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes.

Proc Natl Acad Sci U S A 2016 08 26;113(32):E4716-25. Epub 2016 Jul 26.

Institute for Auditory Neuroscience & InnerEarLab, University Medical Center Göttingen, 37099 Goettingen, Germany; Göttingen Graduate School for Neurosciences and Molecular Biosciences, University of Göttingen, 37073 Goettingen, Germany; Bernstein Focus for Neurotechnology, University of Göttingen, 37073 Goettingen, Germany; Collaborative Research Center 889, University of Göttingen, 37099 Goettingen, Germany; Synaptic Nanophysiology Group, Max Planck Institute for Biophysical Chemistry, 37077 Goettingen, Germany; Center for Nanoscale Microscopy and Molecular Physiology of the Brain, University of Göttingen, 37073 Goettingen, Germany; Bernstein Center for Computational Neuroscience, University of Göttingen, 37073 Goettingen, Germany

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http://dx.doi.org/10.1073/pnas.1605737113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987782PMC
August 2016

Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing.

EMBO J 2015 Nov 7;34(21):2686-702. Epub 2015 Oct 7.

Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany Collaborative Research Center 889, University of Göttingen, Göttingen, Germany Synaptic Nanophysiology Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany Center for Nanoscale Microscopy and Molecular Physiology of the Brain, University of Göttingen, Göttingen, Germany

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http://dx.doi.org/10.15252/embj.201591885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641533PMC
November 2015

Synaptic encoding and processing of auditory information in physiology and disease.

Hear Res 2015 Dec 26;330(Pt B):155-6. Epub 2015 Jun 26.

Collaborative Research Center 889, University of Göttingen, Göttingen, Germany; Auditory Systems Physiology Group, InnerEarLab, Department of Otolaryngology, University of Göttingen Medical Center, Göttingen, Germany.

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http://dx.doi.org/10.1016/j.heares.2015.06.015DOI Listing
December 2015

Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones.

Proc Natl Acad Sci U S A 2015 Jun 1;112(24):E3141-9. Epub 2015 Jun 1.

Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37099 Göttingen, Germany; Center for Nanoscale Microscopy and Molecular Physiology of the Brain, University of Göttingen, 37099 Göttingen, Germany; Collaborative Sensory Research Center 889, University of Göttingen, 37099 Göttingen, Germany; Bernstein Center for Computational Neuroscience, University of Göttingen, 37073 Göttingen, Germany;

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http://dx.doi.org/10.1073/pnas.1417207112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475996PMC
June 2015

EF-hand protein Ca2+ buffers regulate Ca2+ influx and exocytosis in sensory hair cells.

Proc Natl Acad Sci U S A 2015 Mar 17;112(9):E1028-37. Epub 2015 Feb 17.

Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37099 Göttingen, Germany; Collaborative Research Center 889, University of Göttingen, 37099 Göttingen, Germany; Bernstein Center for Computational Neuroscience, Göttingen University, 37077 Göttingen, Germany;

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http://dx.doi.org/10.1073/pnas.1416424112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352837PMC
March 2015

Optogenetic stimulation of the auditory nerve.

J Vis Exp 2014 Oct 8(92):e52069. Epub 2014 Oct 8.

InnerEarLab, Department of Otolaryngology, University Medical Center Goettingen; Bernstein Focus for Neurotechnology, University of Goettingen; Center for Nanoscale Microscopy and Molecular Physiology of the Brain, University of Goettingen;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841303PMC
http://dx.doi.org/10.3791/52069DOI Listing
October 2014

The Clouston syndrome mutation connexin30 A88V leads to hyperproliferation of sebaceous glands and hearing impairments in mice.

FEBS Lett 2014 May 29;588(9):1795-801. Epub 2014 Mar 29.

LIMES (Life and Medical Science Institute), Molecular Genetics, University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2014.03.040DOI Listing
May 2014

Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse.

EMBO J 2014 Mar 17;33(5):512-27. Epub 2014 Jan 17.

InnerEarLab, Department of Otolaryngology, University Medical Center Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1002/embj.201385887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989631PMC
March 2014

Mastoid cavity obliteration and Vibrant Soundbridge implantation for patients with mixed hearing loss.

Laryngoscope 2014 Feb 5;124(2):531-7. Epub 2013 Aug 5.

Department for Otolaryngology, University of Göttingen Medical Center, Germany.

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http://dx.doi.org/10.1002/lary.24180DOI Listing
February 2014

Concurrent maturation of inner hair cell synaptic Ca2+ influx and auditory nerve spontaneous activity around hearing onset in mice.

J Neurosci 2013 Jun;33(26):10661-6

InnerEarLab, Auditory Systems Physiology Group, Department of Otolaryngology, and Collaborative Research Center 889, University Medical Center Göttingen, D-37099 Göttingen, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.1215-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618488PMC
June 2013

Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.

Neuron 2013 Jul 13;79(1):82-96. Epub 2013 Jun 13.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.neuron.2013.05.011DOI Listing
July 2013

Connexin32 can restore hearing in connexin26 deficient mice.

Eur J Cell Biol 2011 Oct 2;90(10):817-24. Epub 2011 Aug 2.

Institute of Genetics, University of Bonn, 53117 Bonn, Germany.

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http://dx.doi.org/10.1016/j.ejcb.2011.05.001DOI Listing
October 2011

The connexin26 S17F mouse mutant represents a model for the human hereditary keratitis-ichthyosis-deafness syndrome.

Hum Mol Genet 2011 Jan 6;20(1):28-39. Epub 2010 Oct 6.

Institut for Genetik, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.

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http://dx.doi.org/10.1093/hmg/ddq429DOI Listing
January 2011

Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells.

Nat Neurosci 2010 Jul 20;13(7):869-76. Epub 2010 Jun 20.

InnerEarLab, Department of Otolaryngology and Center for Molecular Physiology of the Brain, University Medical Center Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1038/nn.2578DOI Listing
July 2010

Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons.

J Neurosci 2010 Jun;30(22):7587-97

Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0389-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901931PMC
June 2010

The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing.

J Neurosci 2009 Aug;29(34):10730-40

InnerEarLab, Department of Otolaryngology and Center for Molecular Physiology of the Brain, Göttingen Graduate School for Neurosciences and Molecular Biosciences, 37099 Göttingen, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.1577-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661046PMC
August 2009

Endocochlear potential depends on Cl- channels: mechanism underlying deafness in Bartter syndrome IV.

EMBO J 2008 Nov 2;27(21):2907-17. Epub 2008 Oct 2.

Leibniz-Institut für Molekulare Pharmakologie, Max-Delbrück-Centrum für Molekulare Medizin (MDC), Berlin, Germany.

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http://emboj.embopress.org/cgi/doi/10.1038/emboj.2008.203
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http://dx.doi.org/10.1038/emboj.2008.203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580783PMC
November 2008

CSPalpha-deficiency causes massive and rapid photoreceptor degeneration.

Proc Natl Acad Sci U S A 2006 Feb 13;103(8):2926-31. Epub 2006 Feb 13.

Institut für Anatomie und Zellbiologie, Universität des Saarlandes Homburg/Saar, Homburg, 66421 Saarland, Germany.

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http://dx.doi.org/10.1073/pnas.0510060103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413794PMC
February 2006

BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments.

J Cell Biol 2004 Sep 20;166(7):983-90. Epub 2004 Sep 20.

Medical School, University of Technology-Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.1083/jcb.200408007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172023PMC
September 2004