Nicola Silvestris

Nicola Silvestris

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Nicola Silvestris

Publications by authors named "Nicola Silvestris"

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Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities.

Cancers (Basel) 2019 Sep 24;11(10). Epub 2019 Sep 24.

Department of Clinical Medicine and Surgery, University of Naples "Federico II", 80131 Naples, Italy.

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http://dx.doi.org/10.3390/cancers11101419DOI Listing
September 2019

Skeletal Metastases of Unknown Primary: Biological Landscape and Clinical Overview.

Cancers (Basel) 2019 Aug 29;11(9). Epub 2019 Aug 29.

Department of Biomedical Sciences and Human Oncology, University of Bari "Ando Moro", Piazza Giulio Cesare, 11, 70124 Bari, Italy.

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http://dx.doi.org/10.3390/cancers11091270DOI Listing
August 2019

Independent Negative Prognostic Role of TCF1 Expression within the Wnt/β-Catenin Signaling Pathway in Primary Breast Cancer Patients.

Cancers (Basel) 2019 Jul 22;11(7). Epub 2019 Jul 22.

Functional Biomorphology Laboratory, IRCCS Istituto Tumori "Giovanni Paolo II" of Bari, 70124 Bari, Italy.

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http://dx.doi.org/10.3390/cancers11071035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678184PMC
July 2019

Inflammatory cells infiltrate and angiogenesis in locally advanced and metastatic cholangiocarcinoma.

Eur J Clin Invest 2019 May 3;49(5):e13087. Epub 2019 Mar 3.

Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, Bari, Italy.

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http://dx.doi.org/10.1111/eci.13087DOI Listing
May 2019

Prediction of survival with second-line therapy in biliary tract cancer: Actualisation of the AGEO CT2BIL cohort and European multicentre validations.

Eur J Cancer 2019 Apr 1;111:94-106. Epub 2019 Mar 1.

Methodology and Quality of Life in Oncology Unit, Besançon University Hospital, Besançon, France; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, F-25000, Besançon, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.01.019DOI Listing
April 2019

Strategies to Improve Cancer Immune Checkpoint Inhibitors Efficacy, Other Than Abscopal Effect: A Systematic Review.

Cancers (Basel) 2019 Apr 15;11(4). Epub 2019 Apr 15.

Scientific Guidance, IRCCS Istituto Tumori "Giovanni Paolo II", Viale Orazio Flacco, 65, 70124 Bari, Italy.

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https://www.mdpi.com/2072-6694/11/4/539
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http://dx.doi.org/10.3390/cancers11040539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521062PMC
April 2019

Intratumoral, rather than stromal, CD8+ T cells could be a potential negative prognostic marker in invasive breast cancer patients.

Transl Oncol 2019 Mar 22;12(3):585-595. Epub 2019 Jan 22.

Functional Biomorphology Laboratory, IRCCS Istituto Tumori "Giovanni Paolo II" di Bari, Italia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19365233183054
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http://dx.doi.org/10.1016/j.tranon.2018.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350084PMC
March 2019

Focus on pancreatic cancer.

Dig Liver Dis 2018 12 17;50(12):1272-1273. Epub 2018 Sep 17.

Pancreatic Surgery Unit, Pancreas Translational and Research Institute, Scientific Institute, San Raffaele Hospital, University Vita e Salute, Milan, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15908658183094
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http://dx.doi.org/10.1016/j.dld.2018.09.003DOI Listing
December 2018

Mast cells and angiogenesis in pancreatic ductal adenocarcinoma.

Clin Exp Med 2018 Aug 28;18(3):319-323. Epub 2018 Feb 28.

Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, Bari, Italy.

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http://dx.doi.org/10.1007/s10238-018-0493-6DOI Listing
August 2018

Immune Prophets of Lung Cancer: The Prognostic and Predictive Landscape of Cellular and Molecular Immune Markers.

Transl Oncol 2018 Jun 3;11(3):825-835. Epub 2018 May 3.

Functional Biomorphology Laboratory, IRCCS-Istituto Tumori, Bari 70124, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2018.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050352PMC
June 2018

Immunological mutational signature in adenosquamous cancer of pancreas: an exploratory study of potentially therapeutic targets.

Expert Opin Ther Targets 2018 05 27;22(5):453-461. Epub 2018 Mar 27.

c Pharmacogenetics and Molecular Diagnostic Unit , Istituto Tumori "Giovanni Paolo II" , Bari , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14728222.2018.1
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http://dx.doi.org/10.1080/14728222.2018.1456530DOI Listing
May 2018

Molecular profiling of pancreatic neuroendocrine tumors (pNETS) and the clinical potential.

Expert Rev Gastroenterol Hepatol 2018 May 18;12(5):471-478. Epub 2018 Apr 18.

c Phase I-Early Clinical Trials Unit, Oncology Department , Antwerp University Hospital & Center for Oncological Research (CORE) , Antwerp , Belgium.

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http://dx.doi.org/10.1080/17474124.2018.1463157DOI Listing
May 2018

NHERF1 and tumor microenvironment: a new scene in invasive breast carcinoma.

J Exp Clin Cancer Res 2018 May 2;37(1):96. Epub 2018 May 2.

Functional Biomorphology Laboratory, IRCCS-Istituto Tumori "Giovanni Paolo II", 70124, Bari, Italy.

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http://dx.doi.org/10.1186/s13046-018-0766-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930748PMC
May 2018

The role of inflammatory cytokines and tumor associated macrophages (TAMs) in microenvironment of pancreatic cancer.

Cytokine Growth Factor Rev 2018 02 12;39:46-61. Epub 2018 Jan 12.

Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Sheffield, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2018.01.007DOI Listing
February 2018

Angiogenesis in adenosquamous cancer of pancreas.

Oncotarget 2017 Nov 27;8(56):95773-95779. Epub 2017 Sep 27.

Molecular Genetics Laboratory, IRCCS Istituto Tumori "Giovanni Paolo II", 70124, Bari, Italy.

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http://dx.doi.org/10.18632/oncotarget.21319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707059PMC
November 2017

Liquid dynamic medicine and N-of-1 clinical trials: a change of perspective in oncology research.

J Exp Clin Cancer Res 2017 09 13;36(1):128. Epub 2017 Sep 13.

Department of Medical Sciences of the University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1186/s13046-017-0598-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598055PMC
September 2017

Molecular classifications of gastric cancers: Novel insights and possible future applications.

World J Gastrointest Oncol 2017 May;9(5):194-208

Silvio Ken Garattini, Debora Basile, Monica Cattaneo, Valentina Fanotto, Elena Ongaro, Marta Bonotto, Paola Ermacora, Giovanni Gerardo Cardellino, Mariella Giovannoni, Nicoletta Pella, Gianpiero Fasola, Giuseppe Aprile, Department of Oncology, University and General Hospital, 33100 Udine, Italy.

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http://dx.doi.org/10.4251/wjgo.v9.i5.194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434387PMC
May 2017

Hepatocellular carcinoma treatment over sorafenib: epigenetics, microRNAs and microenvironment. Is there a light at the end of the tunnel?

Expert Opin Ther Targets 2015 27;19(12):1623-35. Epub 2015 Jul 27.

i 9 National Cancer Research Centre "Giovanni Paolo II", Medical Oncology Unit , Viale Orazio Flacco, 65, 70124 Bari, Italy +39 080 555 5419 ; +39 080 555 5419 ;

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http://dx.doi.org/10.1517/14728222.2015.1071354DOI Listing
September 2016

Total and not bevacizumab-bound vascular endothelial growth factor as potential predictive factors to bevacizumab-based chemotherapy in colorectal cancer.

World J Gastroenterol 2016 Jul;22(27):6287-95

Amalia Azzariti, Letizia Porcelli, Michele Signorile, Anna Elisa Quatrale, Clinical and Preclinical Pharmacology Laboratory, National Cancer Research Centre Istituto Tumori Giovanni Paolo II, 70124 Bari, Italy.

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http://dx.doi.org/10.3748/wjg.v22.i27.6287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945987PMC
July 2016

Prolonged Drainage and Intrapericardial Bleomycin Administration for Cardiac Tamponade Secondary to Cancer-Related Pericardial Effusion.

Medicine (Baltimore) 2016 Apr;95(15):e3273

From the Medical Oncology, Azienda Ospedaliera SS Antonio e Biagio e C Arrigo, Alessandria (GN, PP); Medical Oncology and Hematology (AC, AM) and Cardiology (MS), Azienda USL della Valle d'Aosta, Aosta; Medical Oncology, Azienda Ospedaliera S. Croce e Carle, Cuneo (MO, EF, IC, MM); and Medical Oncology Unit, National Cancer Research Centre "Giovanni Paolo II", Bari (NS), Italy.

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http://dx.doi.org/10.1097/MD.0000000000003273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839808PMC
April 2016

Neoadjuvant multimodal treatment of pancreatic ductal adenocarcinoma.

Crit Rev Oncol Hematol 2016 Feb 23;98:309-24. Epub 2015 Nov 23.

Medical Oncology Clinic, AOU Ospedali Riuniti, Polytechnic University of the Marche Region, Ancona, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2015.11.016DOI Listing
February 2016

Metastatic gastric cancer in the last two decades: goals achieved and future promises.

Future Oncol 2015 Oct 11;11(19):2633-2636. Epub 2015 Sep 11.

Department of Oncology, University Hospital, Cagliari, Italy.

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http://dx.doi.org/10.2217/fon.15.214DOI Listing
October 2015

Robotic radiosurgery in pancreatic cancer: A systematic review.

World J Gastroenterol 2015 Aug;21(31):9420-9

Milly Buwenge, Francesco Deodato, Gabriella Macchia, Department of Radiation Oncology, Università Cattolica del Sacro Cuore, 86100 Campobasso, Italy.

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http://dx.doi.org/10.3748/wjg.v21.i31.9420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541395PMC
August 2015

Metronomic chemotherapy from rationale to clinical studies: a dream or reality?

Crit Rev Oncol Hematol 2015 Jul 20;95(1):46-61. Epub 2015 Jan 20.

Medical Oncology Unit, National Cancer Research Centre "Giovanni Paolo II", Bari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2015.01.008DOI Listing
July 2015

Cancer survivorship: long-term side-effects of anticancer treatments of gastrointestinal cancer.

Curr Opin Oncol 2015 Jul;27(4):351-7

aMedical Oncology and Hematology, Ospedale U.Parini, Aosta bMedical Oncology Unit, 'Mons R Dimiccoli' Hospital, Barletta cMedical Oncology Unit, National Cancer Institute 'Giovanni Paolo II', Bari, Italy.

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http://dx.doi.org/10.1097/CCO.0000000000000203DOI Listing
July 2015

Active treatment given in the last weeks of life: poor quality cancer care or justifiable behavior?

Support Care Cancer 2014 Oct 11;22(10):2813-9. Epub 2014 May 11.

Department of Medical Oncology, U. Parini General Hospital, Viale Ginevra 3, 11100, Aosta, Italy,

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http://dx.doi.org/10.1007/s00520-014-2268-2DOI Listing
October 2014

Target therapies in pancreatic carcinoma.

Curr Med Chem 2014 ;21(8):948-65

Medical Oncology Unit, National Cancer Research Centre - Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124 Bari, Italy.

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http://dx.doi.org/10.2174/09298673113209990238DOI Listing
September 2014

Targeted therapies in upper gastrointestinal malignancies.

Curr Med Chem 2014 ;21(8):947

Clinical and Preclinical Pharmacology Lab. National Cancer Research Centre Istituto Tumori Giovanni Paolo II Viale Orazio Flacco, 65 70124 Bari Italy.

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http://dx.doi.org/10.2174/09298673113209990230DOI Listing
September 2014

CES2, ABCG2, TS and Topo-I primary and synchronous metastasis expression and clinical outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI regimen.

Int J Mol Sci 2014 Sep 5;15(9):15767-77. Epub 2014 Sep 5.

Functional Biomorphology Laboratory, National Cancer Research Centre-Istituto Tumori "Giovanni Paolo II", Viale Orazio Flacco 65, 70124 Bari, Italy.

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http://dx.doi.org/10.3390/ijms150915767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200864PMC
September 2014

Challenges and opportunities of microRNAs in lymphomas.

Molecules 2014 Sep 17;19(9):14723-81. Epub 2014 Sep 17.

Haematology Unit, National Cancer Research Centre, Istituto Tumori "Giovanni Paolo II", Bari 70124, Italy.

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http://dx.doi.org/10.3390/molecules190914723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271734PMC
September 2014

Third-line trabectedin for a metastatic desmoplastic small round cell tumour treated with multimodal therapy.

Anticancer Res 2014 Jul;34(7):3683-8

Medical Oncology Unit, National Cancer Institute "Giovanni Paolo II", Bari, Italy.

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July 2014

The role of micro-RNAs in hepatocellular carcinoma: from molecular biology to treatment.

Molecules 2014 May 19;19(5):6393-406. Epub 2014 May 19.

Department of Medical Oncology, Università Politecnica delle Marche, A.O.U. "Ospedali Riuniti" Via Conca 71, 60126 Ancona, Italy.

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http://dx.doi.org/10.3390/molecules19056393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271763PMC
May 2014

Role of microRNA in response to ionizing radiations: evidences and potential impact on clinical practice for radiotherapy.

Molecules 2014 Apr 24;19(4):5379-401. Epub 2014 Apr 24.

Radiation Oncology Department, Università Cattolica del Sacro Cuore; L.go Francesco Vito 1, 00168 Roma, Italy.

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http://dx.doi.org/10.3390/molecules19045379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271831PMC
April 2014

Complete response to second line Paclitaxel every 2 weeks of eyelid kaposi sarcoma: a case report.

Ophthalmic Plast Reconstr Surg 2013 Sep-Oct;29(5):e114-5

*Scientific Direction, †Hematology Unit, ‡Medical and Experimental Oncology Unit, Cancer Institute "Giovanni Paolo II", Bari, Italy.

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http://dx.doi.org/10.1097/IOP.0b013e3182776f32DOI Listing
February 2014

Clinical application of microRNA testing in neuroendocrine tumors of the gastrointestinal tract.

Molecules 2014 Feb 21;19(2):2458-68. Epub 2014 Feb 21.

ARC-Net Research Centre, University and Hospital Trust of Verona, Verona 37134, Italy.

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http://dx.doi.org/10.3390/molecules19022458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271745PMC
February 2014

Optimal control of nausea and vomiting with a three-drug antiemetic regimen with aprepitant in metastatic pancreatic cancer patients treated with first-line modified FOLFIRINOX.

Support Care Cancer 2013 Nov 23;21(11):2955-6. Epub 2013 Aug 23.

Medical Oncology Unit, National Cancer Institute "Giovanni Paolo II", Viale Orazio Flacco, 65, 70124, Bari, Italy,

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http://dx.doi.org/10.1007/s00520-013-1944-yDOI Listing
November 2013

Expression and prognostic value of VEGFR-2, PDGFR-β, and c-Met in advanced hepatocellular carcinoma.

J Exp Clin Cancer Res 2013 Apr 3;32:16. Epub 2013 Apr 3.

The Affiliated Hospital Cancer Center, Academy of Military Medical Sciences, Beijing 100071, People's Republic of China.

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http://dx.doi.org/10.1186/1756-9966-32-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623756PMC
April 2013

Author's reply: To PMID 22443211.

Expert Opin Ther Targets 2013 Apr;17(4):474-5

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April 2013