Nicola Santoro

Nicola Santoro

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Nicola Santoro

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Metabolic and Genetic Determinants of Glucose Shape After Oral Challenge in Obese Youths: A Longitudinal Study.

J Clin Endocrinol Metab 2020 Feb;105(2)

Department of Pediatrics, Pediatrics Endocrinology and Diabetes Section, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1210/clinem/dgz207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977541PMC
February 2020

Cardiovascular dysfunction and vitamin D status in childhood acute lymphoblastic leukemia survivors.

World J Pediatr 2019 Oct 4;15(5):465-470. Epub 2019 May 4.

Department of Pediatric Oncology and Hematology, University Hospital of Policlinico, Piazza G. Cesare 11, 70124, Bari, Italy.

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http://dx.doi.org/10.1007/s12519-019-00258-yDOI Listing
October 2019

Primary Orbital Synovial Sarcoma Mimicking a Periocular Cyst.

Am J Dermatopathol 2019 Sep;41(9):655-660

Unit of Ocular Oncology, Department of Surgery and Translational Medicine, Careggi University Hospital, Florence, Italy.

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http://Insights.ovid.com/crossref?an=00000372-900000000-9822
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http://dx.doi.org/10.1097/DAD.0000000000001351DOI Listing
September 2019

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.

Authors:
Jason Flannick Josep M Mercader Christian Fuchsberger Miriam S Udler Anubha Mahajan Jennifer Wessel Tanya M Teslovich Lizz Caulkins Ryan Koesterer Francisco Barajas-Olmos Thomas W Blackwell Eric Boerwinkle Jennifer A Brody Federico Centeno-Cruz Ling Chen Siying Chen Cecilia Contreras-Cubas Emilio Córdova Adolfo Correa Maria Cortes Ralph A DeFronzo Lawrence Dolan Kimberly L Drews Amanda Elliott James S Floyd Stacey Gabriel Maria Eugenia Garay-Sevilla Humberto García-Ortiz Myron Gross Sohee Han Nancy L Heard-Costa Anne U Jackson Marit E Jørgensen Hyun Min Kang Megan Kelsey Bong-Jo Kim Heikki A Koistinen Johanna Kuusisto Joseph B Leader Allan Linneberg Ching-Ti Liu Jianjun Liu Valeriya Lyssenko Alisa K Manning Anthony Marcketta Juan Manuel Malacara-Hernandez Angélica Martínez-Hernández Karen Matsuo Elizabeth Mayer-Davis Elvia Mendoza-Caamal Karen L Mohlke Alanna C Morrison Anne Ndungu Maggie C Y Ng Colm O'Dushlaine Anthony J Payne Catherine Pihoker Wendy S Post Michael Preuss Bruce M Psaty Ramachandran S Vasan N William Rayner Alexander P Reiner Cristina Revilla-Monsalve Neil R Robertson Nicola Santoro Claudia Schurmann Wing Yee So Xavier Soberón Heather M Stringham Tim M Strom Claudia H T Tam Farook Thameem Brian Tomlinson Jason M Torres Russell P Tracy Rob M van Dam Marijana Vujkovic Shuai Wang Ryan P Welch Daniel R Witte Tien-Yin Wong Gil Atzmon Nir Barzilai John Blangero Lori L Bonnycastle Donald W Bowden John C Chambers Edmund Chan Ching-Yu Cheng Yoon Shin Cho Francis S Collins Paul S de Vries Ravindranath Duggirala Benjamin Glaser Clicerio Gonzalez Ma Elena Gonzalez Leif Groop Jaspal Singh Kooner Soo Heon Kwak Markku Laakso Donna M Lehman Peter Nilsson Timothy D Spector E Shyong Tai Tiinamaija Tuomi Jaakko Tuomilehto James G Wilson Carlos A Aguilar-Salinas Erwin Bottinger Brian Burke David J Carey Juliana C N Chan Josée Dupuis Philippe Frossard Susan R Heckbert Mi Yeong Hwang Young Jin Kim H Lester Kirchner Jong-Young Lee Juyoung Lee Ruth J F Loos Ronald C W Ma Andrew D Morris Christopher J O'Donnell Colin N A Palmer James Pankow Kyong Soo Park Asif Rasheed Danish Saleheen Xueling Sim Kerrin S Small Yik Ying Teo Christopher Haiman Craig L Hanis Brian E Henderson Lorena Orozco Teresa Tusié-Luna Frederick E Dewey Aris Baras Christian Gieger Thomas Meitinger Konstantin Strauch Leslie Lange Niels Grarup Torben Hansen Oluf Pedersen Philip Zeitler Dana Dabelea Goncalo Abecasis Graeme I Bell Nancy J Cox Mark Seielstad Rob Sladek James B Meigs Steve S Rich Jerome I Rotter David Altshuler Noël P Burtt Laura J Scott Andrew P Morris Jose C Florez Mark I McCarthy Michael Boehnke

Nature 2019 06 22;570(7759):71-76. Epub 2019 May 22.

Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.

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http://www.nature.com/articles/s41586-019-1231-2
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http://dx.doi.org/10.1038/s41586-019-1231-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699738PMC
June 2019

One-hour post-load plasma glucose predicts progression to prediabetes in a multi-ethnic cohort of obese youths.

Diabetes Obes Metab 2019 05 28;21(5):1191-1198. Epub 2019 Feb 28.

Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1111/dom.13640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459710PMC
May 2019

Arsenic trioxide and all-trans retinoic acid treatment for childhood acute promyelocytic leukaemia.

Br J Haematol 2019 Apr 20;185(2):360-363. Epub 2018 Jul 20.

Department of Paediatric Haematology/Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.1111/bjh.15507DOI Listing
April 2019

A low visceral fat proportion, independent of total body fat mass, protects obese adolescent girls against fatty liver and glucose dysregulation: a longitudinal study.

Int J Obes (Lond) 2019 04 18;43(4):673-682. Epub 2018 Oct 18.

Department of Pediatrics, Division of Pediatric Endocrinology, Yale University School of Medicine, New Haven, CT, 06520, USA.

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http://dx.doi.org/10.1038/s41366-018-0227-6DOI Listing
April 2019

Relation of the degree of obesity in childhood to adipose tissue insulin resistance.

Acta Diabetol 2019 Feb 12;56(2):219-226. Epub 2019 Jan 12.

Department of Pediatrics, Ruth Rappaport Children's Hospital, Rambam Medical Center, Haifa, Israel.

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http://dx.doi.org/10.1007/s00592-018-01285-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373259PMC
February 2019

Triglyceride-rich very low-density lipoproteins (VLDL) are independently associated with insulin secretion in a multiethnic cohort of adolescents.

Diabetes Obes Metab 2018 12 2;20(12):2905-2910. Epub 2018 Aug 2.

Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1111/dom.13467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231949PMC
December 2018

Predictors of responses to clinic-based childhood obesity care.

Pediatr Diabetes 2018 12 1;19(8):1351-1356. Epub 2018 Oct 1.

Ruth Rappaport Children's Hospital, Rambam Medical Center, Haifa, Israel.

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http://dx.doi.org/10.1111/pedi.12774DOI Listing
December 2018

Thrombotic Thrombocytopenic Purpura in a Child Treated for Acute Lymphoblastic Leukemia: Case Report and Review of Literature.

J Pediatr Hematol Oncol 2018 10;40(7):558-559

Division of Paediatric Haematology-Oncology, University of Bari, Bari, Italy.

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http://dx.doi.org/10.1097/MPH.0000000000001050DOI Listing
October 2018

Trajectories of changes in glucose tolerance in a multiethnic cohort of obese youths: an observational prospective analysis.

Lancet Child Adolesc Health 2018 10 24;2(10):726-735. Epub 2018 Aug 24.

Department of Pediatrics, Division of Pediatric Endocrinology, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(18)30235-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190831PMC
October 2018

The rs626283 Variant in the MBOAT7 Gene is Associated with Insulin Resistance and Fatty Liver in Caucasian Obese Youth.

Am J Gastroenterol 2018 03 27;113(3):376-383. Epub 2018 Feb 27.

Department of Pediatrics, Section of Endocrinology, Yale School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/ajg.2018.1DOI Listing
March 2018

Prediabetes in youth - mechanisms and biomarkers.

Lancet Child Adolesc Health 2017 Nov 26;1(3):240-248. Epub 2017 Sep 26.

Department of Pediatrics, Division of Pediatric Endocrinology, , Yale University School of Medicine, New Haven, CT 06520.

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http://dx.doi.org/10.1016/S2352-4642(17)30044-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652329PMC
November 2017

Cytomegalovirus Cavitary Pneumonia in Nontransplant Pediatric Acute Lymphoblastic Leukemia: Case Report and Review of the Literature.

J Pediatr Hematol Oncol 2017 08;39(6):e318-e320

Department of Paediatrics, Division of Paediatric Haematology-Oncology, Bari, Italy.

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http://dx.doi.org/10.1097/MPH.0000000000000901DOI Listing
August 2017

The Association between Pediatric NAFLD and Common Genetic Variants.

Children (Basel) 2017 Jun 18;4(6). Epub 2017 Jun 18.

Department of Pediatrics, Yale University, 06520, New Haven, CT, USA.

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http://dx.doi.org/10.3390/children4060049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483624PMC
June 2017

Endothelial dysfunction and cardiovascular risk factors in childhood acute lymphoblastic leukemia survivors.

Int J Cardiol 2017 Feb 9;228:621-627. Epub 2016 Nov 9.

Department of Biomedicine and Human Oncology, Pediatric Section, University "A. Moro" of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2016.11.025DOI Listing
February 2017

From the liver to the heart: Cardiac dysfunction in obese children with non-alcoholic fatty liver disease.

World J Hepatol 2017 Jan;9(2):69-73

Anna Di Sessa, Giuseppina Rosaria Umano, Emanuele Miraglia del Giudice, Department of Woman and Child and General and Specialized Surgery, Seconda Università degli Studi di Napoli, 80138 Naples, Italy.

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http://dx.doi.org/10.4254/wjh.v9.i2.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241530PMC
January 2017

Role of Gut Microbiota and Short Chain Fatty Acids in Modulating Energy Harvest and Fat Partitioning in Youth.

J Clin Endocrinol Metab 2016 11 20;101(11):4367-4376. Epub 2016 Sep 20.

Department of Pediatrics (M.G., M.S., B.P., N.S.), Yale University, New Haven, Connecticut; Universita' Milano Bicocca (M.G.), Milano, Italy; Department of Molecular & Cell Biology (K.M., E.A.M., J.G.), University of Connecticut, Storrs, Connecticut; Department of Medicine (E.J.P.), University of Missouri, Columbia, Missouri; Metabolic Solutions Inc. (D.A.W.), Nashua, New Hampshire; Department of Internal Medicine (G.C.), Yale University, New Haven, Connecticut.

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http://dx.doi.org/10.1210/jc.2016-1797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095239PMC
November 2016

Adipose Insulin Resistance in Obese Adolescents Across the Spectrum of Glucose Tolerance.

J Clin Endocrinol Metab 2016 06 7;101(6):2423-31. Epub 2016 Apr 7.

Department of Human Metabolism and Nutrition (K.H., O.B., R.W.), Braun School of Public Health, Hebrew University, Jerusalem 91120, Israel; and the Department of Pediatrics (N.S., B.P., S.C.), Yale School of Medicine, New Haven, Connecticut 06510.

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http://dx.doi.org/10.1210/jc.2016-1376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891802PMC
June 2016

Non Activated Protein C Supplementation in Septic Pediatric Hematological Patients.

Pediatr Rep 2016 Jun 15;8(2):6488. Epub 2016 Jun 15.

Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of Bari , Italy.

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http://dx.doi.org/10.4081/pr.2016.6488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933811PMC
June 2016

Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.

J Immunol 2016 Jan 18;196(1):437-47. Epub 2015 Nov 18.

Department of Biochemistry, McGill University, Montreal, Quebec H3G 1Y6, Canada; Department of Medicine, McGill University, Montreal, Quebec H3G 0B1, Canada; Department of Microbiology and Immunology McGill University, Montreal, Quebec H3A 2B4, Canada;

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http://www.jimmunol.org/content/early/2015/11/18/jimmunol.15
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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1501529
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http://dx.doi.org/10.4049/jimmunol.1501529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594569PMC
January 2016

Recurrent Rhino-Ocular-Cerebral Mucormycosis in a Leukemic Child: A Case Report and Review of Pediatric Literature.

Pediatr Rep 2015 Sep 28;7(3):5938. Epub 2015 Sep 28.

Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of Bari , Italy.

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http://dx.doi.org/10.4081/pr.2015.5938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594447PMC
September 2015

Hepatic De Novo Lipogenesis in Obese Youth Is Modulated by a Common Variant in the GCKR Gene.

J Clin Endocrinol Metab 2015 Aug 4;100(8):E1125-32. Epub 2015 Jun 4.

Department of Pediatrics (N.S., S.C., B.P., M.V.N., M.S.), Yale University School of Medicine, New Haven, Connecticut 06520; and Department of Medicine (E.J.P.), University of Missouri, Colombia, Missouri 65211.

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http://dx.doi.org/10.1210/jc.2015-1587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524990PMC
August 2015

A common variant in the MTNR1b gene is associated with increased risk of impaired fasting glucose (IFG) in youth with obesity.

Obesity (Silver Spring) 2015 May;23(5):1022-9

Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.

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http://dx.doi.org/10.1002/oby.21030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414047PMC
May 2015

Targeting BAG-1: a novel strategy to increase drug efficacy in acute myeloid leukemia.

Exp Hematol 2015 Mar 11;43(3):180-190.e6. Epub 2014 Nov 11.

Women and Child Health Department, Hematology-Oncology Laboratory Istituto di Ricerca Pediatrica (IRP), University of Padova, Padova, Italy.

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http://dx.doi.org/10.1016/j.exphem.2014.10.016DOI Listing
March 2015

Blunted suppression of acyl-ghrelin in response to fructose ingestion in obese adolescents: the role of insulin resistance.

Obesity (Silver Spring) 2015 Mar 3;23(3):653-61. Epub 2015 Feb 3.

Department of Pediatrics, Division of Pediatric Endocrinology, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1002/oby.21019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548801PMC
March 2015

Invasive fungal infections in patients with hematologic malignancies (aurora project): lights and shadows during 18-months surveillance.

Int J Mol Sci 2012 13;13(1):774-87. Epub 2012 Jan 13.

Hygiene Section, Department of Biomedical Science and Human Oncology, University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy; E-Mails: (O.D.G.); (C.N.); (G.L.); (G.C.).

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http://dx.doi.org/10.3390/ijms13010774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269719PMC
February 2015

Mediastinal Burkitt lymphoma in childhood.

Pediatr Blood Cancer 2014 Nov 22;61(11):2127-8. Epub 2014 Jul 22.

Department of Women's and Children's Health, Clinic of Pediatric Hemato-Oncology, University of Padova, Padova, Italy.

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http://doi.wiley.com/10.1002/pbc.25127
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http://dx.doi.org/10.1002/pbc.25127DOI Listing
November 2014

A low disposition index in adolescent offspring of mothers with gestational diabetes: a risk marker for the development of impaired glucose tolerance in youth.

Diabetologia 2014 Nov 29;57(11):2413-20. Epub 2014 Aug 29.

Department of Pediatrics, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208064, New Haven, CT, 06520, USA.

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http://link.springer.com/10.1007/s00125-014-3345-2
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http://dx.doi.org/10.1007/s00125-014-3345-2DOI Listing
November 2014

Metabolic syndrome in pediatrics.

Adv Clin Chem 2014 ;65:91-142

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http://dx.doi.org/10.1016/b978-0-12-800141-7.00004-8DOI Listing
October 2014

Pediatric fatty liver disease: role of ethnicity and genetics.

World J Gastroenterol 2014 Jun;20(23):7347-55

Pierluigi Marzuillo, Emanuele Miraglia del Giudice, Department of Women and Children and General and Specialized Surgery, Seconda Università degli Studi di Napoli, 80138 Naples, Italy.

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http://dx.doi.org/10.3748/wjg.v20.i23.7347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064080PMC
June 2014

Non-activated protein C rescue treatment in Wilms tumour associated hepatic sinusoidal obstructive syndrome.

Pediatr Blood Cancer 2014 May 26;61(5):940-1. Epub 2013 Nov 26.

Division of Paediatric Haematology-Oncology, Department of Pediatrics, Bari, Italy.

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http://doi.wiley.com/10.1002/pbc.24859
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http://dx.doi.org/10.1002/pbc.24859DOI Listing
May 2014

Pediatric non-alcoholic fatty liver disease: New insights and future directions.

World J Hepatol 2014 Apr;6(4):217-25

Pierluigi Marzuillo, Emanuele Miraglia del Giudice, Department of women and children and General and Specialized Surgery, Seconda Università degli Studi di Napoli, 80138 Naples, Italy.

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http://dx.doi.org/10.4254/wjh.v6.i4.217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009477PMC
April 2014

The many faces of diabetes: a disease with increasing heterogeneity.

Lancet 2014 Mar 3;383(9922):1084-94. Epub 2013 Dec 3.

Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(13)62219-9DOI Listing
March 2014

Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis in obese adolescents: a looming marker of cardiac dysfunction.

Hepatology 2014 Feb 16;59(2):372-4. Epub 2013 Dec 16.

Department of Pediatrics, Yale University School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1002/hep.26663DOI Listing
February 2014

Oxidized fatty acids: A potential pathogenic link between fatty liver and type 2 diabetes in obese adolescents?

Antioxid Redox Signal 2014 Jan 3;20(2):383-9. Epub 2013 Aug 3.

1 Department of Pediatrics, Yale University School of Medicine , New Haven, Connecticut.

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http://dx.doi.org/10.1089/ars.2013.5466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887421PMC
January 2014

Type 2 diabetes mellitus in pediatrics: a new challenge.

World J Pediatr 2013 Nov 14;9(4):293-9. Epub 2013 Nov 14.

Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1007/s12519-013-0438-9DOI Listing
November 2013

Metabolic syndrome in pediatrics: old concepts revised, new concepts discussed.

Curr Probl Pediatr Adolesc Health Care 2013 May-Jun;43(5):114-23

Department of Pediatrics, Yale University School of Medicine, PO Box 208064, New Haven, CT, USA.

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http://dx.doi.org/10.1016/j.cppeds.2013.02.004DOI Listing
October 2013

Oxidized metabolites of linoleic acid as biomarkers of liver injury in nonalcoholic steatohepatitis.

Clin Lipidol 2013 Aug;8(4):411-418

Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.2217/clp.13.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578804PMC
August 2013

Circulating levels of FGF-21 in obese youth: associations with liver fat content and markers of liver damage.

J Clin Endocrinol Metab 2013 Jul 26;98(7):2993-3000. Epub 2013 Apr 26.

Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1210/jc.2013-1250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701279PMC
July 2013

Childhood obesity and type 2 diabetes: the frightening epidemic.

Authors:
Nicola Santoro

World J Pediatr 2013 May 16;9(2):101-2. Epub 2013 May 16.

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http://dx.doi.org/10.1007/s12519-013-0410-8DOI Listing
May 2013

The SDQ in Italian clinical practice: evaluation between three outpatient groups compared.

Riv Psichiatr 2012 Sep-Oct;47(5):400-6

Department of Neurologic and Psychiatric Sciences, University Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.1708/1175.13030DOI Listing
January 2013

Metabolic syndrome in youth: current insights and novel serum biomarkers.

Biomark Med 2012 Dec;6(6):719-27

Department of Pediatrics, Yale University School of Medicine, 330 Cedar Street, PO Box 208064, New Haven, CT 06520, USA.

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http://dx.doi.org/10.2217/bmm.12.85DOI Listing
December 2012

Guillain-Barré-like syndrome in a child with lead poisoning.

Neuropediatrics 2012 Aug 30;43(4):217-20. Epub 2012 Jun 30.

Department of Neurologic and Psychiatric Sciences, Child Neuropsychiatry Unit, University of Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.1055/s-0032-1321981DOI Listing
August 2012

Necrotizing fasciitis of the lower limbs.

Pediatr Rep 2012 Jan 22;4(1):e4. Epub 2012 Feb 22.

U.O. Pediatria F. Vecchio Oncoematologia Pediatrica;

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http://dx.doi.org/10.4081/pr.2012.e4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357617PMC
January 2012