Publications by authors named "Nicola Perrotti"

50Publications

Generation of iPSC lines from two patients affected by febrile seizure due to inherited missense mutation in SCN1A gene.

Authors:
Stefania Scalise Luana Scaramuzzino Valeria Lucchino Claudia Esposito Paola Malatesta Katia Grillone Nicola Perrotti Giovanni Cuda Elvira Immacolata Parrotta

Stem Cell Res 2020 Dec 7;49:102083. Epub 2020 Nov 7.

Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University "Magna Graecia" of Catanzaro, Italy.

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December 2020

The Emerging Role of SGK1 (Serum- and Glucocorticoid-Regulated Kinase 1) in Major Depressive Disorder: Hypothesis and Mechanisms.

Authors:
Vincenzo Dattilo Rosario Amato Nicola Perrotti Massimo Gennarelli

Front Genet 2020 5;11:826. Epub 2020 Aug 5.

Genetic Unit, IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.

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August 2020

7q35 Microdeletion and 15q13.3 and Xp22.33 Microduplications in a Patient with Severe Myoclonic Epilepsy, Microcephaly, Dysmorphisms, Severe Psychomotor Delay and Intellectual Disability.

Authors:
Francesco Paduano Emma Colao Sara Loddo Valeria Orlando Francesco Trapasso Antonio Novelli Nicola Perrotti Rodolfo Iuliano

Genes (Basel) 2020 05 8;11(5). Epub 2020 May 8.

Medical Genetics Unit, University "Magna Graecia", 88100 Catanzaro, Italy.

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May 2020

A familial t(4;8) translocation segregates with epilepsy and migraine with aura.

Authors:
Milena Crippa Paola Malatesta Maria Teresa Bonati Francesco Trapasso Francesco Fortunato Grazia Annesi Lidia Larizza Angelo Labate Palma Finelli Nicola Perrotti Antonio Gambardella

Ann Clin Transl Neurol 2020 05 21;7(5):855-859. Epub 2020 Apr 21.

Institute of Neurology, University Magna Graecia, Catanzaro, Italy.

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May 2020

Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition.

Authors:
Giada Catalogna Federica Moraca Lucia D'Antona Vincenzo Dattilo Giuseppe Perrotti Antonio Lupia Giosuè Costa Francesco Ortuso Rodolfo Iuliano Francesco Trapasso Rosario Amato Stefano Alcaro Nicola Perrotti

Eur J Med Chem 2019 Dec 5;183:111675. Epub 2019 Sep 5.

Dipartimento di Medicina Sperimentale e Clinica, University "Magna Græcia" of Catanzaro, Viale Europa, 88100, Catanzaro, Italy. Electronic address:

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December 2019

A novel variant causative of pseudoxanthoma elasticum.

Authors:
Gianluca Contrò Rossana Tallerico Vincenzo Dattilo Fernanda Fabiani Maria Vittoria Enzo Uros Hladnik Stefano Dastoli Steven Paul Nisticò Emma Colao Nicola Perrotti Rodolfo Iuliano

Hum Genome Var 2019 20;6:30. Epub 2019 Jun 20.

1Medical Genetics Unit, University "Magna Graecia", Catanzaro, Italy.

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June 2019

In Preclinical Model of Ovarian Cancer, the SGK1 Inhibitor SI113 Counteracts the Development of Paclitaxel Resistance and Restores Drug Sensitivity.

Authors:
Lucia D'Antona Vincenzo Dattilo Giada Catalogna Domenica Scumaci Claudia Vincenza Fiumara Francesca Musumeci Giuseppe Perrotti Silvia Schenone Rossana Tallerico Cristina B Spoleti Nicola Costa Rodolfo Iuliano Giovanni Cuda Rosario Amato Nicola Perrotti

Transl Oncol 2019 Aug 1;12(8):1045-1055. Epub 2019 Jun 1.

Department of "Scienze della Salute", University "Magna Graecia" of Catanzaro, Viale Europa, Catanzaro. Electronic address:

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August 2019

The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells.

Authors:
Silvia Matteoni Claudia Abbruzzese Paola Matarrese Gabriele De Luca Anna M Mileo Stefania Miccadei Silvia Schenone Francesca Musumeci Tobias L Haas Giovanni Sette Carmine M Carapella Rosario Amato Nicola Perrotti Michele Signore Marco G Paggi

J Exp Clin Cancer Res 2019 May 17;38(1):202. Epub 2019 May 17.

Section of Cellular Networks and Molecular Therapeutic Targets, Proteomics Unit, IRCCS - Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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May 2019

The small molecule SI113 hinders epithelial-to-mesenchymal transition and subverts cytoskeletal organization in human cancer cells.

Authors:
Claudia Abbruzzese Silvia Matteoni Michele Persico Barbara Ascione Silvia Schenone Francesca Musumeci Rosario Amato Nicola Perrotti Paola Matarrese Marco G Paggi

J Cell Physiol 2019 12 16;234(12):22529-22542. Epub 2019 May 16.

Division of Cellular Networks and Molecular Therapeutic Targets, Proteomics Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy.

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December 2019

Functional characterization of p.Pro409His variant in HNF1A, a hypomorphic mutation involved in pancreatic β-cell dysfunction.

Authors:
Donatella Nocera Miranda Menniti Stefania Belviso Heather Mandy Bond Delia Lanzillotta Cristina Barbara Spoleti Maria Rosaria Guagliardi Paola Malatesta Francesco Trapasso Concetta Irace Nicola Perrotti Rodolfo Iuliano

Acta Diabetol 2019 Aug 9;56(8):883-888. Epub 2019 Apr 9.

Unit of Medical Genetics, University Hospital Mater Domini, Viale T. Campanella, 115, Catanzaro, Italy.

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August 2019

Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition.

Authors:
Rosa Sottile Giorgia Federico Cinzia Garofalo Rossana Tallerico Maria Concetta Faniello Barbara Quaresima Costanza Maria Cristiani Maddalena Di Sanzo Gianni Cuda Valeria Ventura Arnika Kathleen Wagner Gianluca Contrò Nicola Perrotti Elio Gulletta Soldano Ferrone Klas Kärre Francesco Saverio Costanzo Francesca Carlomagno Ennio Carbone

Front Immunol 2019 26;10:224. Epub 2019 Feb 26.

Tumor Immunology and Immunopathology Laboratory, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.

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September 2020

Biallelic variants in the ciliary gene TMEM67 cause RHYNS syndrome.

Authors:
Francesco Brancati Letizia Camerota Emma Colao Virginia Vega-Warner Xiangzhong Zhao Ruixiao Zhang Irene Bottillo Marco Castori Alfredo Caglioti Federica Sangiuolo Giuseppe Novelli Nicola Perrotti Edgar A Otto

Eur J Hum Genet 2018 09 11;26(9):1266-1271. Epub 2018 Jun 11.

Division of Nephrology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.

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September 2018

The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells.

Authors:
Sabrina D'Agostino Delia Lanzillotta Mariaconcetta Varano Cirino Botta Antonio Baldrini Anna Bilotta Stefania Scalise Vincenzo Dattilo Rosario Amato Eugenio Gaudio Francesco Paduano Camillo Palmieri Rodolfo Iuliano Nicola Perrotti Cesare Indiveri Alfredo Fusco Marco Gaspari Francesco Trapasso

Oncotarget 2018 May 4;9(34):23334-23348. Epub 2018 May 4.

Dipartimento di Medicina Sperimentale e Clinica, University Magna Græcia, Campus "S. Venuta", Catanzaro, Italy.

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May 2018

Deregulation of SGK1 in Ulcerative Colitis: A Paradoxical Relationship Between Immune Cells and Colonic Epithelial Cells.

Authors:
Rocco Spagnuolo Vincenzo Dattilo Lucia D'Antona Cristina Cosco Rossana Tallerico Valeria Ventura Francesco Conforti Caterina Camastra Rosellina M Mancina Giada Catalogna Vincenzo Cosco Rodolfo Iuliano Ennio Carbone Nicola Perrotti Rosario Amato Patrizia Doldo

Inflamm Bowel Dis 2018 08;24(9):1967-1977

Departments of "Scienze Mediche e Chirurgiche,", Catanzaro, Italy.

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August 2018

Real-life 3D therapy failure: Analysis of NS5A 93H RAS plus 108 K polymorphism in complex with ombitasvir by molecular modeling.

Authors:
Nadia Marascio Grazia Pavia Isabella Romeo Carmine Talarico Sebastiano Di Salvo Mariaconcetta Reale Vito Marano Giorgio Settimo Barreca Fernanda Fabiani Nicola Perrotti Massimo De Siena Francesca Giancotti Tiziana Gravina Stefano Alcaro Anna Artese Carlo Torti Maria Carla Liberto Alfredo Focà

J Med Virol 2018 07 31;90(7):1257-1263. Epub 2018 Mar 31.

Department of Health Sciences, Unit of Clinical Microbiology, School of Medicine, University of "Magna Graecia", Catanzaro, Italy.

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July 2018

The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme.

Authors:
Claudia Abbruzzese Giada Catalogna Enzo Gallo Simona di Martino Anna M Mileo Mariantonia Carosi Vincenzo Dattilo Silvia Schenone Francesca Musumeci Patrizia Lavia Nicola Perrotti Rosario Amato Marco G Paggi

Oncotarget 2017 Dec 18;8(67):110743-110755. Epub 2017 Nov 18.

Department of Research, Advanced Diagnostics and Technological Innovation, Unit of Cellular Networks and Therapeutic Targets, "Regina Elena" National Cancer Institute, IRCCS, Rome, Italy.

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December 2017

The SGK1 Kinase Inhibitor SI113 Sensitizes Theranostic Effects of the 64CuCl2 in Human Glioblastoma Multiforme Cells.

Authors:
Giada Catalogna Cristina Talarico Vincenzo Dattilo Vincenzo Gangemi Ferdinando Calabria Lucia D'Antona Silvia Schenone Francesca Musumeci Cataldo Bianco Nicola Perrotti Rosario Amato Giuseppe L Cascini

Cell Physiol Biochem 2017 25;43(1):108-119. Epub 2017 Aug 25.

University "Magna Graecia" of Catanzaro, Dept. of "Medicina Sperimentale e Clinica", Catanzaro, Italy.

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November 2017

The human asparaginase enzyme (ASPG) inhibits growth in leukemic cells.

Authors:
Stefania Belviso Rodolfo Iuliano Rosario Amato Nicola Perrotti Miranda Menniti

PLoS One 2017 24;12(5):e0178174. Epub 2017 May 24.

Department of Human Health, University Magna Graecia of Catanzaro, Catanzaro, Italy.

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September 2017

SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation.

Authors:
Vincenzo Dattilo Lucia D'Antona Cristina Talarico Mjriam Capula Giada Catalogna Rodolfo Iuliano Silvia Schenone Sante Roperto Cataldo Bianco Nicola Perrotti Rosario Amato

Sci Rep 2017 03 30;7:45361. Epub 2017 Mar 30.

University "Magna Graecia" of Catanzaro, Dept. of "Scienze della Salute", Viale Europa Catanzaro, Italy.

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March 2017

The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells.

Authors:
Domenico Conza Paola Mirra Gaetano Calì Teresa Tortora Luigi Insabato Francesca Fiory Silvia Schenone Rosario Amato Francesco Beguinot Nicola Perrotti Luca Ulianich

J Cell Physiol 2017 Dec 27;232(12):3735-3743. Epub 2017 Apr 27.

Department of Medical and Translational Sciences of the University of Naples "Federico II" & URT dell'Istituto di Endocrinologia e Oncologia Sperimentale 'Gaetano Salvatore', Consiglio Nazionale delle Ricerche, Naples, Italy.

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December 2017