Nicola Pavese

Nicola Pavese

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Nicola Pavese

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Clinical implications of early caudate dysfunction in Parkinson's disease.

J Neurol Neurosurg Psychiatry 2019 Oct 11;90(10):1098-1104. Epub 2019 May 11.

Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK

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http://dx.doi.org/10.1136/jnnp-2018-320157DOI Listing
October 2019

The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy.

Mov Disord 2019 Sep 12;34(9):1307-1314. Epub 2019 Jul 12.

Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.27786DOI Listing
September 2019

Traditional trial-and-error versus neuroanatomical-3D-image software-assisted deep brain stimulation programming in patients with Parkinson's disease.

World Neurosurg 2019 Sep 27. Epub 2019 Sep 27.

Division of Brain Sciences, Imperial College London , UK.

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http://dx.doi.org/10.1016/j.wneu.2019.09.106DOI Listing
September 2019

Pedunculopontine and Subthalamic Nucleus Stimulation Effect on Saccades in Parkinson Disease.

World Neurosurg 2019 Jun 22;126:e219-e231. Epub 2019 Feb 22.

Imperial College Neuromodulation Group, Centre for Restorative Neuroscience, Division of Brain Sciences, Charing Cross Hospital Campus, London, United Kingdom.

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http://dx.doi.org/10.1016/j.wneu.2019.02.014DOI Listing
June 2019

PET Molecular Imaging in Atypical Parkinsonism.

Int Rev Neurobiol 2018 8;142:3-36. Epub 2018 Oct 8.

Newcastle University Newcastle Magnetic Resonance Centre & Positron Emission Tomography Centre, Newcastle University Campus for Ageing & Vitality, Newcastle upon Tyne, United Kingdom; Department of Clinical Medicine-Positron Emission Tomography Centre, Aarhus University, Aarhus, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00747742183010
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http://dx.doi.org/10.1016/bs.irn.2018.09.001DOI Listing
May 2019

PET Evaluation of Microglial Activation in Non-neurodegenerative Brain Diseases.

Curr Neurol Neurosci Rep 2019 May 28;19(7):38. Epub 2019 May 28.

The Edmond J. Safra Program in Parkinson's Disease & Movement Disorder Unit, Toronto Western Hospital & Krembil Research Institute, University Health Network; Research Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s11910-019-0951-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538572PMC
May 2019

New and Old TSPO PET Radioligands for Imaging Brain Microglial Activation in Neurodegenerative Disease.

Curr Neurol Neurosci Rep 2019 Apr 2;19(5):24. Epub 2019 Apr 2.

The Edmond J. Safra Program in Parkinson's Disease & Movement Disorder Unit, Toronto Western Hospital & Krembil Research Institute, University Health Network; Research Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s11910-019-0934-yDOI Listing
April 2019

Progressive loss of raphe nuclei serotonin transporter in early Parkinson's disease: A longitudinal I-FP-CIT SPECT study.

Parkinsonism Relat Disord 2019 Apr 5. Epub 2019 Apr 5.

Institute of Neuroscience, Newcastle University, UK; Department of Nuclear Medicine & PET Centre, Aarhus University, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.03.025DOI Listing
April 2019

Rare histotype of sporadic Creutzfeldt-Jakob disease, clinically suspected as corticobasal degeneration.

BMJ Case Rep 2019 Mar 7;12(3). Epub 2019 Mar 7.

Institute of Neuroscience, Newcastle University, Newcastle Upon Tyne, UK.

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http://dx.doi.org/10.1136/bcr-2018-228305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424260PMC
March 2019

Is neuromelanin the imaging biomarker for the early diagnosis of Parkinson's disease that we were looking for?

Authors:
Nicola Pavese

Parkinsonism Relat Disord 2019 01 13;58:1-2. Epub 2018 Dec 13.

Institute of Neuroscience, Faculty of Medical Sciences, Newcastle University, UK; Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Nørrebrogade 44, 8000, Aarhus, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.12.013DOI Listing
January 2019

Imaging Markers of Progression in Parkinson's Disease.

Mov Disord Clin Pract 2018 Nov-Dec;5(6):586-596. Epub 2018 Oct 9.

Parkinson's Disease Research Clinic, Brain and Mind Centre University of Sydney Sydney NSW Australia.

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http://dx.doi.org/10.1002/mdc3.12673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277366PMC
October 2018

Extrastriatal monoaminergic dysfunction and enhanced microglial activation in idiopathic rapid eye movement sleep behaviour disorder.

Neurobiol Dis 2018 07 6;115:9-16. Epub 2018 Mar 6.

Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Denmark; Division of Neuroscience, Newcastle University, England, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.02.017DOI Listing
July 2018

In-vivo staging of pathology in REM sleep behaviour disorder: a multimodality imaging case-control study.

Lancet Neurol 2018 07 1;17(7):618-628. Epub 2018 Jun 1.

Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30162-5DOI Listing
July 2018

Pallidal dopaminergic denervation and rest tremor in early Parkinson's disease: PPMI cohort analysis.

Parkinsonism Relat Disord 2018 06 24;51:101-104. Epub 2018 Feb 24.

Division of Brain Sciences, Neurology Imaging Unit, Imperial College London, Hammersmith Campus, UK.

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http://dx.doi.org/10.1016/j.parkreldis.2018.02.039DOI Listing
June 2018

A noninterventional study evaluating the effectiveness of rotigotine and levodopa combination therapy in younger versus older patients with Parkinson's disease.

Expert Opin Pharmacother 2018 Jun 19;19(9):937-945. Epub 2018 Jun 19.

j National Parkinson Foundation Centre of Excellence and The Maurice Wohl Clinical Neuroscience Institute, King's College London and King's College Hospital , London , UK.

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http://dx.doi.org/10.1080/14656566.2018.1480721DOI Listing
June 2018

Nigrosome Imaging and Neuromelanin Sensitive MRI in Diagnostic Evaluation of Parkinsonism.

Mov Disord Clin Pract 2018 Mar-Apr;5(2):131-140. Epub 2018 Feb 22.

Division of Brain Sciences Imperial College London London United Kingdom.

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http://doi.wiley.com/10.1002/mdc3.12590
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http://dx.doi.org/10.1002/mdc3.12590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174398PMC
February 2018

Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: A clinical review.

Mov Disord 2018 01 28;33(1):10-20. Epub 2017 Sep 28.

Movement Disorders Center, Division of Neurology, Centre Hospitalier Universitaire (CHU) Grenoble, Grenoble Alpes University, Grenoble, France.

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http://dx.doi.org/10.1002/mds.27098DOI Listing
January 2018

Assessment of neuroinflammation in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study.

Lancet Neurol 2017 10 3;16(10):789-796. Epub 2017 Jul 3.

Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark; Institute of Neuroscience, Newcastle University, Newcastle, England. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30173-4DOI Listing
October 2017

Biased numerical cognition impairs economic decision-making in Parkinson's disease.

Ann Clin Transl Neurol 2017 10 8;4(10):739-748. Epub 2017 Sep 8.

Division of Brain Sciences Imperial College Charing Cross Hospital Campus Fulham Palace Road London W6 8RF United Kingdom.

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http://dx.doi.org/10.1002/acn3.449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634350PMC
October 2017

Genetic and degenerative disorders primarily causing other movement disorders.

Handb Clin Neurol 2016 ;135:507-523

Division of Brain Sciences, Imperial College London, UK.

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http://dx.doi.org/10.1016/B978-0-444-53485-9.00025-8DOI Listing
February 2017

Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients.

Mov Disord 2017 02 17;32(2):235-240. Epub 2016 Nov 17.

Centre for Neurodegeneration and Neuroinflammation, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1002/mds.26848DOI Listing
February 2017

Decreased intestinal acetylcholinesterase in early Parkinson disease: An C-donepezil PET study.

Neurology 2017 Feb 18;88(8):775-781. Epub 2017 Jan 18.

From the Department of Nuclear Medicine and PET-Centre (T.D.F., L.B.S., K.K., A.C.S., N.P., D.J.B., P.B.) and Department of Neurology (J.G.), Aarhus University Hospital, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000003633DOI Listing
February 2017

Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers.

Mov Disord 2017 02 2;32(2):181-192. Epub 2017 Feb 2.

Morton and Gloria Shulman Movement Disorder Unit & E.J. Safra Parkinson Disease Program, Neurology Div/Dept. Medicine, Toronto Western Hospital, UHN; Krembil Research Institute, UHN; Research Imaging Centre, Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/mds.26907DOI Listing
February 2017

A Network Model of Local Field Potential Activity in Essential Tremor and the Impact of Deep Brain Stimulation.

PLoS Comput Biol 2017 01 9;13(1):e1005326. Epub 2017 Jan 9.

Division of Brain Sciences, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pcbi.1005326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261813PMC
January 2017

Sleep problems and hypothalamic dopamine D3 receptor availability in Parkinson disease.

Neurology 2016 Dec 2;87(23):2451-2456. Epub 2016 Nov 2.

From the Division of Brain Sciences (G.P., P.G.B., D.J.B., N.P.), Imperial College London; Imperial College NHS Trust (S.M.); Imanova Ltd (E.A.R.); National Parkinson Foundation International Centre of Excellence (E.A.R.), King's College London and National Institute for Health Research Biomedical Research Centre and King's College London; Institute of Neuroscience (D.J.B., N.P.), Newcastle University, UK; and Institute of Clinical Medicine (D.J.B., N.P.), University of Aarhus, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000003396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177673PMC
December 2016

Age at onset and Parkinson disease phenotype.

Neurology 2016 Apr 10;86(15):1400-1407. Epub 2016 Feb 10.

From the Department of Medicine (G.P., D.J.B., N.P.), Neurology Imaging Unit, Imperial College London, Hammersmith Hospital, London, UK; Department of Translational Medical Sciences (G.P., N.F.), Federico II University of Naples; Salvatore Maugeri Foundation (N.F.), IRCCS, Scientific Institute of Telese, Telese Terme (BN), Italy; and Department of Clinical Medicine-Center for Functionally Integrative Neuroscience (D.J.B., N.P.), Aarhus University, Denmark.

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http://www.neurology.org/content/early/2016/02/10/WNL.000000
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http://dx.doi.org/10.1212/WNL.0000000000002461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831034PMC
April 2016

Progression of nonmotor symptoms in subgroups of patients with non-dopamine-deficient Parkinsonism.

Mov Disord 2016 Mar 11;31(3):344-51. Epub 2016 Feb 11.

Division of Brain Sciences, Imperial College London, UK.

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http://dx.doi.org/10.1002/mds.26456DOI Listing
March 2016

Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease.

Brain 2015 Oct 23;138(Pt 10):2964-73. Epub 2015 Jul 23.

1 Division of Brain Sciences, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK 3 Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus, Denmark

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http://dx.doi.org/10.1093/brain/awv215DOI Listing
October 2015

Imaging the aetiology of sleep disorders in dementia and Parkinson's disease.

Authors:
Nicola Pavese

Curr Neurol Neurosci Rep 2014 Dec;14(12):501

Division of Brain Sciences-Neurology Imaging Unit (NIU), Imperial College London, 1st Floor, B Block Hammersmith Campus DuCane Road, London, W12 0NN, UK,

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http://dx.doi.org/10.1007/s11910-014-0501-5DOI Listing
December 2014

Reversing the polarity of bipolar stimulation in deep brain stimulation for essential tremor: a theoretical explanation for a useful clinical intervention.

Neurocase 2014 24;20(1):10-7. Epub 2012 Sep 24.

a Department of Medicine , Centre for Neuroscience, Imperial College London , London , UK.

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http://dx.doi.org/10.1080/13554794.2012.713495DOI Listing
July 2014

Brain shaving: adaptive detection for brain PET data.

Phys Med Biol 2014 May 28;59(10):2517-34. Epub 2014 Apr 28.

Department of Imaging Sciences and Biomedical Engineering, King's College, London, UK.

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http://dx.doi.org/10.1088/0031-9155/59/10/2517DOI Listing
May 2014

Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART.

AIDS 2014 Jan;28(1):67-72

aDepartment of Medicine, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Norfolk Place bDepartment of HIV and GU Medicine, Imperial College Healthcare NHS Trust cDivision of Brain Sciences, Imperial College London, Hammersmith Hospital Campus, London, UK.

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http://dx.doi.org/10.1097/01.aids.0000432467.54003.f7DOI Listing
January 2014

Benefits of putaminal GDNF infusion in Parkinson disease are maintained after GDNF cessation.

Neurology 2013 Sep 14;81(13):1176-8. Epub 2013 Aug 14.

From the Institute of Clinical Neurosciences (N.K.P., S.J., S.S.G.), Frenchay Hospital, Bristol; and Imperial College London (N.P., G.R.H., D.J.B.), Division of Brain Sciences, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1212/WNL.0b013e3182a55ea5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795600PMC
September 2013

Brain metabolism in patients with hepatic encephalopathy studied by PET and MR.

Arch Biochem Biophys 2013 Aug 30;536(2):131-42. Epub 2013 May 30.

Department of Hepato-Gastroenterology, Aarhus University Hospital, 8000 Aarhus, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S00039861130015
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http://dx.doi.org/10.1016/j.abb.2013.05.006DOI Listing
August 2013

Dystonia: hopes for a better diagnosis and a treatment with long-lasting effect.

Authors:
Nicola Pavese

Brain 2013 Mar;136(Pt 3):694-5

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http://dx.doi.org/10.1093/brain/awt028DOI Listing
March 2013

Spatiotemporal visualization of deep brain stimulation-induced effects in the subthalamic nucleus.

Eur J Neurosci 2012 Jul;36(2):2252-9

Centre for Neuroscience, Imperial College London, Charing Cross Hospital, London, UK.

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http://dx.doi.org/10.1111/j.1460-9568.2012.08086.xDOI Listing
July 2012

Brain monoamine systems in multiple system atrophy: a positron emission tomography study.

Neurobiol Dis 2012 Apr 12;46(1):130-6. Epub 2012 Jan 12.

Centre for Neuroscience, Dept of Medicine, Imperial College London, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1016/j.nbd.2011.12.053DOI Listing
April 2012

Do we still need to develop new imaging biomarkers of dopamine denervation for Parkinson's disease?

Authors:
Nicola Pavese

Exp Neurol 2012 Jan 20;233(1):118-20. Epub 2011 Oct 20.

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http://dx.doi.org/10.1016/j.expneurol.2011.10.008DOI Listing
January 2012

PET studies in Parkinson's disease motor and cognitive dysfunction.

Authors:
Nicola Pavese

Parkinsonism Relat Disord 2012 Jan;18 Suppl 1:S96-9

Centre for Neuroscience, Department of Medicine, Imperial College London, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1016/S1353-8020(11)70031-1DOI Listing
January 2012

Imaging biomarkers in Parkinson's disease.

Prog Neurobiol 2011 Dec 30;95(4):614-28. Epub 2011 Aug 30.

Centre for Neuroscience, Department of Medicine, Imperial College London, UK.

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http://dx.doi.org/10.1016/j.pneurobio.2011.08.009DOI Listing
December 2011

Progression of monoaminergic dysfunction in Parkinson's disease: a longitudinal 18F-dopa PET study.

Neuroimage 2011 Jun 17;56(3):1463-8. Epub 2011 Mar 17.

Centre for Neuroscience, Department of Medicine, Imperial College London, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2011.03.012DOI Listing
June 2011

Global-two-stage filtering of clinical PET parametric maps: application to [(11)C]-(R)-PK11195.

Neuroimage 2011 Apr 30;55(3):942-53. Epub 2010 Dec 30.

MRC Clinical Sciences Center and Division of Medicine, Imperial College, London, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2010.12.056DOI Listing
April 2011

Glutamate NMDA receptor dysregulation in Parkinson's disease with dyskinesias.

Brain 2011 Apr 2;134(Pt 4):979-86. Epub 2011 Mar 2.

Centre for Neuroscience, Imperial College, London, UK.

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http://dx.doi.org/10.1093/brain/awr028DOI Listing
April 2011

Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study.

Hum Brain Mapp 2011 Feb;32(2):258-70

Department of Clinical Neurosciences and MRC Clinical Sciences Centre, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1002/hbm.21008DOI Listing
February 2011

Imaging non-motor aspects of Parkinson's disease.

Prog Brain Res 2010 ;184:205-18

Division of Experimental Medicine, Imperial College London, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1016/S0079-6123(10)84011-7DOI Listing
January 2011

Fatigue in Parkinson's disease is linked to striatal and limbic serotonergic dysfunction.

Brain 2010 Nov 30;133(11):3434-43. Epub 2010 Sep 30.

Department of Medicine, Centre for Neuroscience, Imperial College, London, UK.

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http://dx.doi.org/10.1093/brain/awq268DOI Listing
November 2010

In vivo assessment of brain monoamine systems in parkin gene carriers: a PET study.

Exp Neurol 2010 Mar 4;222(1):120-4. Epub 2010 Jan 4.

MRC Clinical Science Centre and Division of Neuroscience and Mental Health, Imperial College, London, UK.

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http://dx.doi.org/10.1016/j.expneurol.2009.12.021DOI Listing
March 2010

Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers.

Neurobiol Dis 2010 Feb 22;37(2):356-61. Epub 2009 Oct 22.

MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1016/j.nbd.2009.10.015DOI Listing
February 2010

Neuroprotection and imaging studies in Parkinson's disease.

Parkinsonism Relat Disord 2009 Dec;15 Suppl 4:S33-7

Division of Neurosciences and Mental Health and MRC Clinical Sciences Centre, Faculty of Medicine, Hammersmith Hospital, Imperial College, London, UK.

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http://dx.doi.org/10.1016/S1353-8020(09)70832-6DOI Listing
December 2009

Nigrostriatal dysfunction in homozygous and heterozygous parkin gene carriers: an 18F-dopa PET progression study.

Mov Disord 2009 Nov;24(15):2260-6

MRC Clinical Science Centre, Imperial College, London, United Kingdom. nicola.pavese@ csc.mrc.ac.uk

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http://dx.doi.org/10.1002/mds.22817DOI Listing
November 2009

Recent imaging advances in the diagnosis and management of Parkinson's disease.

F1000 Med Rep 2009 Oct 29;1. Epub 2009 Oct 29.

MRC Clinical Sciences Centre and Division of Neurosciences & Mental Health, Imperial College London Cyclotron Building, Hammersmith Hospital, Du Cane Road, London W12 0NN UK.

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http://dx.doi.org/10.3410/M1-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948338PMC
October 2009

Imaging neurodegeneration in Parkinson's disease.

Biochim Biophys Acta 2009 Jul 17;1792(7):722-9. Epub 2008 Oct 17.

MRC Clinical Sciences Centre and Division of Neuroscience and Mental Health, Faculty of Medicine, Imperial College London, UK.

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http://dx.doi.org/10.1016/j.bbadis.2008.10.003DOI Listing
July 2009

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study.

Neurobiol Dis 2008 Dec 15;32(3):412-9. Epub 2008 Aug 15.

MRC Clinical Sciences Centre, Cyclotron Building Hammersmith Hospital, Imperial College London, UK.

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http://dx.doi.org/10.1016/j.nbd.2008.08.001DOI Listing
December 2008

Evidence of dopamine dysfunction in the hypothalamus of patients with Parkinson's disease: an in vivo 11C-raclopride PET study.

Exp Neurol 2008 Nov 6;214(1):112-6. Epub 2008 Aug 6.

Division of Neuroscience and MRC Clinical Sciences Centre, Faculty of Medicine, Cyclotron Building, Hammersmith Hospital, Imperial College London, DuCane Road W12 0NN, London, UK.

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http://dx.doi.org/10.1016/j.expneurol.2008.07.021DOI Listing
November 2008

Hypothalamic involvement in Huntington's disease: an in vivo PET study.

Brain 2008 Nov 1;131(Pt 11):2860-9. Epub 2008 Oct 1.

Division of Clinical Neurosciences and MRC Clinical Sciences Centre, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1093/brain/awn244DOI Listing
November 2008

Cognitive deficits and striato-frontal dopamine release in Parkinson's disease.

Brain 2008 May 24;131(Pt 5):1294-302. Epub 2008 Mar 24.

Division of Neuroscience, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/awn054DOI Listing
May 2008

PET image denoising using a synergistic multiresolution analysis of structural (MRI/CT) and functional datasets.

J Nucl Med 2008 Apr 14;49(4):657-66. Epub 2008 Mar 14.

Department of Clinical Neuroscience, Division of Neuroscience and Mental Health, Imperial College, London, United Kingdom.

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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.107.041871
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http://dx.doi.org/10.2967/jnumed.107.041871DOI Listing
April 2008

Role of dopamine agonists in Parkinson's disease: an update.

Expert Rev Neurother 2007 Oct;7(10):1391-9

University of Pisa, Department of Neuroscience, Via Roma 67 (56126), Pisa, Italy.

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http://dx.doi.org/10.1586/14737175.7.10.1391DOI Listing
October 2007

Microglial activation in presymptomatic Huntington's disease gene carriers.

Brain 2007 Jul 30;130(Pt 7):1759-66. Epub 2007 Mar 30.

MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/awm044DOI Listing
July 2007

A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195.

Neuroimage 2007 May 21;36(1):28-37. Epub 2007 Feb 21.

Department of Clinical Neuroscience, Division of Neuroscience and Mental Health, Imperial College London, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2007.02.017DOI Listing
May 2007

Imaging microglial activation in Huntington's disease.

Brain Res Bull 2007 Apr 27;72(2-3):148-51. Epub 2006 Nov 27.

Division of Neuroscience and Psychological Medicine, Hammersmith Hospital, Imperial College London, UK.

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http://dx.doi.org/10.1016/j.brainresbull.2006.10.029DOI Listing
April 2007

Reference and target region modeling of [11C]-(R)-PK11195 brain studies.

J Nucl Med 2007 Jan;48(1):158-67

Division of Neuroscience, Department of Clinical Neuroscience, Imperial College London, London, United Kingdom.

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January 2007

Upregulation of dopamine D2 receptors in dopaminergic drug-naive patients with Parkin gene mutations.

Mov Disord 2006 Jun;21(6):783-8

MRC Clinical Science Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.20811DOI Listing
June 2006

Compulsive drug use linked to sensitized ventral striatal dopamine transmission.

Ann Neurol 2006 May;59(5):852-8

Reta Lila Weston Institute of Neurological Studies and the National Hospital for Neurology and Neurosurgery, London, United Kingdom.

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http://doi.wiley.com/10.1002/ana.20822
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http://dx.doi.org/10.1002/ana.20822DOI Listing
May 2006

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease.

Neurobiol Dis 2006 Feb 21;21(2):404-12. Epub 2005 Sep 21.

MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, London, UK.

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http://dx.doi.org/10.1016/j.nbd.2005.08.002DOI Listing
February 2006

Dopamine agonists in the treatment of Parkinson's disease.

Expert Rev Neurother 2006 Jan;6(1):81-9

Department of Neuroscience, University of Pisa, (56126) Pisa, Italy.

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http://dx.doi.org/10.1586/14737175.6.1.81DOI Listing
January 2006

Factors affecting the clinical outcome after neural transplantation in Parkinson's disease.

Brain 2005 Dec 24;128(Pt 12):2977-86. Epub 2005 Oct 24.

MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1093/brain/awh649DOI Listing
December 2005

A technique for standardized central analysis of 6-(18)F-fluoro-L-DOPA PET data from a multicenter study.

J Nucl Med 2004 Jul;45(7):1135-45

Division of Neuroscience and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom.

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July 2004

Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism.

Brain 2004 Jun 16;127(Pt 6):1332-42. Epub 2004 Apr 16.

MRC Clinical Science Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/awh150DOI Listing
June 2004

Cardiovascular effects of methamphetamine in Parkinson's disease patients.

Mov Disord 2004 Mar;19(3):298-303

MRC Clinical Science Center and Division of Neurosciences, Faculty of Medicine, Imperial College. Hammersmith Hospital Campus, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.10651DOI Listing
March 2004

Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

Brain 2003 May;126(Pt 5):1127-35

MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1093/brain/awg119DOI Listing
May 2003

Endogenous dopamine release after pharmacological challenges in Parkinson's disease.

Ann Neurol 2003 May;53(5):647-53

MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.10526DOI Listing
May 2003

Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study.

Brain 2002 Oct;125(Pt 10):2248-56

MRC Clinical Sciences Centre, and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/awf237DOI Listing
October 2002

Dyskinesias following neural transplantation in Parkinson's disease.

Nat Neurosci 2002 Jul;5(7):627-8

Section of Restorative Neurology, Wallenberg Neuroscience Center, SE-221 84 Lund, Sweden.

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http://dx.doi.org/10.1038/nn863DOI Listing
July 2002