Publications by authors named "Nicola D"

21 Publications

  • Page 1 of 1

Checklist of parasites in fish from the upper Paraná River floodplain: An update.

Rev Bras Parasitol Vet 2020 11;29(3):e008720. Epub 2020 Sep 11.

Programa de Pós-graduação em Ecologia de Ambientes Aquáticos Continentais, Universidade Estadual de Maringá - UEM, Maringá, PR, Brasil.

This study provides an updated list of parasite species and their respective hosts in the upper Paraná River floodplain. The list of parasites is structured by phylum, class, order and family, followed by a record of each host species. A total of 315 taxa of parasites were reported, of which 201 were identified at the species level. These 201 species comprise 3 Flagellata, 3 Myxozoa, 50 Monogenea, 43 Digenea, 40 Cestoda, 41 Nematoda, 8 Acanthocephala, 6 Copepoda, 5 Branchiura and 2 Pentastomida, arranged in 84 host fish species. This work carried out in the floodplain of the upper Paraná River contributes to the listing of parasite species and host interactions of the local ichthyofauna. Little is known about these communities and its riches are underestimated due to the high density of fish found in this region, highlighting the importance of conducting studies on the local fauna.
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http://dx.doi.org/10.1590/S1984-29612020066DOI Listing
October 2020

Corpus Luteum Color Doppler Ultrasound and Pregnancy Outcome in Buffalo during the Transitional Period.

Animals (Basel) 2020 Jul 13;10(7). Epub 2020 Jul 13.

Department of Veterinary Medicine and Animal Production, Federico II University, 80137 Naples, Italy.

This study evaluated corpus luteum (CL) development in buffaloes out of breeding season and assessed an early pregnancy diagnosis. Mediterranean buffaloes (n = 29) were synchronized and artificially inseminated. CL B-mode/color Doppler ultrasonography examinations were performed daily from Days 5 to 10 post-synchronization, recording CL dimensions and blood flow parameters. Blood samples were collected on the same days for the progesterone (P) assay. Data were grouped into pregnant or nonpregnant and retrospectively analyzed. The total pregnancy rate was 50.0% (13/26) on Day 45. A significant difference between CL average area in pregnant and nonpregnant buffaloes was recorded only on Day 10. Pregnant buffaloes showed a significantly higher mean P concentration and higher mean time average medium velocity (TAMV) values from Day 5 to Day 10 compared to nonpregnant buffaloes. Linear regression analysis showed a significant relationship between P levels and TAMV. Multiple logistic regression highlighted a significant influence of TAMV on pregnancy outcome, particularly on Day 8. This is probably due to the strong relationship between TAMV and P production. Both TAMV and P could be used to predict pregnancy starting on Day 6, although a more reliable result was obtained at Day 10. Thus, the period between Days 5 and 10 is critical for CL development during the transitional period in buffalo.
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http://dx.doi.org/10.3390/ani10071181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401660PMC
July 2020

Behavioral changes in host foraging: Experiments with Clinostomum (Trematoda, Digenea) parasitizing Loricariichthys platymetopon (Loricariidae).

Exp Parasitol 2020 Sep 23;216:107916. Epub 2020 Jun 23.

Laboratório de Ictioparasitologia, Núcleo de Pesquisas em Limnologia, Ictiologia e Aquicultura-Nupélia, Universidade Estadual de Maringá, Bloco G-90, Av. Colombo, 5790, CEP 87020-900, Maringá, PR, Brazil; Programa de Pós-Graduação em Biologia comparada PGB - UEM, Brazil. Electronic address:

Complex life cycle parasites can manipulate the behavior of intermediate hosts in order to reduce their fitness and increase the chance of completing life cycle. In order to understand the effects of the trematode parasites of the genus Clinostomum on host fish Loricariichthys platymetopon, a filmed experiment was carried out to quantify the foraging activity of hosts with different intensities of infection. The results suggest that hosts with higher parasite intensities reduced foraging activity early in the morning when compared to hosts with low intensities. This period may be critical for hosts since birds, the target hosts of such trematodes, forage intensively at dawn.
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http://dx.doi.org/10.1016/j.exppara.2020.107916DOI Listing
September 2020

Effect of live body weight and method of synchronization on ovulation, pregnancy rate and embryo and fetal loss in buffalo heifers.

Anim Reprod 2019 Nov 18;16(4):859-863. Epub 2019 Nov 18.

Università degli Studi di Napoli "Federico II", Dipartimento di Medicina Veterinaria e Produzioni Animali, Napoli, Italy.

This study aimed to assess the influence of live body weight (LBW) and age on reproductive performance in buffalo heifers synchronized by different treatments. The study was carried out on 146 Mediterranean buffalo heifers (mean age 25.3±13.4 months, LBW 424±47 kg), divided into 2 homogeneous groups and synchronized by Ovsynch-TAI Program (OVS; n = 72) or double prostaglandin administered 12 days apart (PGF; n = 74). All the buffaloes were inseminated twice and follicle dimensions and ovulation rate (OR) were assessed by ultrasound 24 and 48 h post-insemination. Pregnancy was assessed on day 25, 45 and 90 post-insemination and the incidence of late embryonic (LEM) and fetal (FM) mortality were respectively recorded. Data were analyzed by ANOVA, Chi-square test and multiple logistic regression. The LBW was significantly (P<0.05) higher in inseminated animals, compared to those that did not respond to the treatments (450.0±3.2 vs. 423.2±9.6 kg in inseminated and not inseminated heifers, respectively). Total OR was similar between groups, although OR at 24 h tended to be higher (P = 0.06) in OVS (86.7 vs. 72.9% in OVS and PGF, respectively). A (P<0.01) higher LBW was observed in ovulated heifers of PGF, while no differences were recorded in OVS. LBW affected OR (odds ratio = 1,032; P<0.05) only in PGF, while no effects were recorded in OVS. Total pregnancy rate, LEM and FM were similar between groups. In conclusion, the LBW would be considered before including buffalo heifers in a synchronization program and both synchronization treatments can be useful.
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http://dx.doi.org/10.21451/1984-3143-AR2019-0009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189557PMC
November 2019

Milk Metabolomics Reveals Potential Biomarkers for Early Prediction of Pregnancy in Buffaloes Having Undergone Artificial Insemination.

Animals (Basel) 2020 Apr 27;10(5). Epub 2020 Apr 27.

Department of Veterinary Medicine and Animal Production, University of Naples "Federico II", 80137 Naples, Italy.

This study aimed to identify potential biomarkers for early pregnancy diagnosis in buffaloes subjected to artificial insemination (AI). The study was carried out on 10 pregnant and 10 non-pregnant buffaloes that were synchronized by Ovsynch-Timed Artificial Insemination Program and have undergone the first AI. Furthermore, milk samples were individually collected ten days before AI (the start of the synchronization treatment), on the day of AI, day 7 and 18 after AI, and were analyzed by LC-MS. Statistical analysis was carried out by using Mass Profile Professional (Agilent Technologies, Santa Clara, CA, USA). Metabolomic analysis revealed the presence of several metabolites differentially expressed between pregnant and non-pregnant buffaloes. Among these, a total of five metabolites were identified by comparison with an online database and a standard compound as acetylcarnitine (3-Acetoxy-4-(trimethylammonio)butanoate), arginine-succinic acid hydrate, 5'-O-{[3-({4-[(3aminopropyl)amino]butyl}amino)propyl]carbamoyl}-2'-deoxyadenosine, N-(1-Hydroxy-2-hexadecanyl)pentadecanamide, and N-[2,3-Bis(dodecyloxy)propyl]-L-lysinamide). Interestingly, acetylcarnitine was dominant in milk samples collected from non-pregnant buffaloes. The results obtained from milk metabolic profile and hierarchical clustering analysis revealed significant differences between pregnant and non-pregnant buffaloes, as well as in the metabolite expression. Overall, the findings indicate the potential of milk metabolomics as a powerful tool to identify biomarkers of early pregnancy in buffalo undergoing AI.
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http://dx.doi.org/10.3390/ani10050758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277816PMC
April 2020

Reproductive management in buffalo by artificial insemination.

Theriogenology 2020 Jul 20;150:166-172. Epub 2020 Jan 20.

Department of Veterinary Medicine and Animal Production, Federico II University of Naples, Via F. Delpino 1, 80137, Napoli, NA, Italy.

Artificial insemination (AI) is important for genetic improvement and to control the period of breeding in buffalo and has increased significantly over the past 20 years. AI is more difficult in buffalo compared with cattle due to variable estrous cycles, reduced estrous behavior, and reproductive seasonality. The latter is associated with a higher incidence of anestrus and increased embryonic mortality during the nonbreeding season. Protocols to control the stage of the estrous cycle have undergone recent development in buffalo. These protocols are based on the control of both the luteal phase of the cycle, mainly by prostaglandins and progesterone, and follicle development and ovulation, by prostaglandins, progesterone, GnRH, hCG, eCG and estradiol. Protocols that synchronize the time of ovulation enable fixed timed AI, avoiding estrous detection. Factors to consider when selecting an AI protocol include animal category (heifers, primiparous or pluriparous), reproductive status (cyclic or anestrus), and season. This review looks at the current status of estrus synchronization and AI in buffalo and provides some practical suggestions for application of AI in the field.
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http://dx.doi.org/10.1016/j.theriogenology.2020.01.016DOI Listing
July 2020

A Preliminary Study on Metabolome Profiles of Buffalo Milk and Corresponding Mozzarella Cheese: Safeguarding the Authenticity and Traceability of Protected Status Buffalo Dairy Products.

Molecules 2020 Jan 12;25(2). Epub 2020 Jan 12.

Dipartimento di Medicina Veterinaria e Produzioni Animali, University of Naples "Federico II", 80137 Naples, Italy.

The aim of this study is to combine advanced GC-MS and metabolite identification in a robust and repeatable technology platform to characterize the metabolome of buffalo milk and mozzarella cheese. The study utilized eleven dairies located in a protected designation of origin (PDO) region and nine dairies located in non-PDO region in Italy. Samples of raw milk (100 mL) and mozzarella cheese (100 g) were obtained from each dairy. A total of 185 metabolites were consistently detected in both milk and mozzarella cheese. The PLS-DA score plots clearly differentiated PDO and non-PDO milk and mozzarella samples. For milk samples, it was possible to divide metabolites into two classes according to region: those with lower concentrations in PDO samples (galactopyranoside, hydroxybuthyric acid, allose, citric acid) and those with lower concentrations in non-PDO samples (talopyranose, pantothenic acid, mannobiose, etc.,). The same was observed for mozzarella samples with the proportion of some metabolites (talopyranose, 2, 3-dihydroxypropyl icosanoate, etc.,) higher in PDO samples while others (tagatose, lactic acid dimer, ribitol, etc.,) higher in non-PDO samples. The findings establish the utility of GC-MS together with mass spectral libraries as a powerful technology platform to determine the authenticity, and create market protection, for "Mozzarella di Bufala Campana."
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http://dx.doi.org/10.3390/molecules25020304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024333PMC
January 2020

Anesthesia interventions that alter perioperative mortality: a scoping review.

Syst Rev 2018 11 30;7(1):218. Epub 2018 Nov 30.

Department of Anesthesiology and Pain Medicine, The Ottawa Hospital, University of Ottawa, General Campus, 501 Smyth Rd, Critical Care Wing 1401, Ottawa, Ontario, K1H 8L6, Canada.

Background: With over 230 million surgical procedures performed annually worldwide, better application of evidence in anesthesia and perioperative medicine may reduce widespread variation in clinical practice and improve patient care. However, a comprehensive summary of the complete available evidence has yet to be conducted. This scoping review aims to map the existing literature investigating perioperative anesthesia interventions and their potential impact on patient mortality, to inform future knowledge translation and ultimately improve perioperative clinical practice.

Methods: Searches were conducted in MEDLINE, EMBASE, CINAHL, and the Cochrane Library databases from inception to March 2015. Study inclusion criteria were adult patients, surgical procedures requiring anesthesia, perioperative intervention conducted/organized by a professional with training in anesthesia, randomized controlled trials (RCTs), and patient mortality as an outcome. Studies were screened for inclusion, and data was extracted in duplicate by pairs of independent reviewers. Data were extracted, tabulated, and reported thematically.

Results: Among the 10,505 publications identified, 369 RCTs (n = 147,326 patients) met the eligibility criteria. While 15 intervention themes were identified, only 7 themes (39 studies) had a significant impact on mortality: pharmacotherapy (n = 23), nutritional (n = 3), transfusion (n = 4), ventilation (n = 5), glucose control (n = 1), medical device (n = 2), and dialysis (n = 1).

Conclusions: By mapping intervention themes, this scoping review has identified areas requiring further systematic investigation given their potential value for reducing patient mortality as well as areas where continued investment may not be cost-effective given limited evidence for improving survival. This is a key starting point for future knowledge translation to optimize anesthesia practice.
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http://dx.doi.org/10.1186/s13643-018-0863-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267894PMC
November 2018

Identification of Pantropic Canine Coronavirus in a Wolf ( Canis lupus italicus) in Italy.

J Wildl Dis 2019 04 30;55(2):504-508. Epub 2018 Oct 30.

1 Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy.

We report a case in an Italian wolf ( Canis lupus italicus) of pantropic canine coronavirus infection, which has previously been detected only in dogs. The wolf was coinfected by canine parvovirus type 2b and canine adenovirus type 2, which highlighted the crucial role of epidemiologic surveys in European wild carnivores.
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http://dx.doi.org/10.7589/2018-07-182DOI Listing
April 2019

Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine.

Ther Adv Drug Saf 2018 May 6;9(5):237-256. Epub 2018 Feb 6.

Department of Neuroscience, Imaging and Clinical Science, Chair of Psychiatry, University 'G. D'Annunzio', Chieti, Italy.

Clozapine, a dibenzodiazepine developed in 1961, is a multireceptorial atypical antipsychotic approved for the treatment of resistant schizophrenia. Since its introduction, it has remained the drug of choice in treatment-resistant schizophrenia, despite a wide range of adverse effects, as it is a very effective drug in everyday clinical practice. However, clozapine is not considered as a top-of-the-line treatment because it may often be difficult for some patients to tolerate as some adverse effects can be particularly bothersome (i.e. sedation, weight gain, sialorrhea etc.) and it has some other potentially dangerous and life-threatening side effects (i.e. myocarditis, seizures, agranulocytosis or granulocytopenia, gastrointestinal hypomotility etc.). As poor treatment adherence in patients with resistant schizophrenia may increase the risk of a psychotic relapse, which may further lead to impaired social and cognitive functioning, psychiatric hospitalizations and increased treatment costs, clozapine adverse effects are a common reason for discontinuing this medication. Therefore, every effort should be made to monitor and minimize these adverse effects in order to improve their early detection and management. The aim of this paper is to briefly summarize and provide an update on major clozapine adverse effects, especially focusing on those that are severe and potentially life threatening, even if most of the latter are relatively uncommon.
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http://dx.doi.org/10.1177/2042098618756261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956953PMC
May 2018

Dissection of a Limb of a Vertebral Artery Fenestration: Case Report.

Can J Neurol Sci 2016 Mar;43(2):329-31

Ottawa Hospital Research Institute-University of Ottawa.

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http://dx.doi.org/10.1017/cjn.2015.329DOI Listing
March 2016

Fatal hemorrhagic-necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus).

Asian Pac J Trop Biomed 2014 May;4(Suppl 1):S62-5

Clinica per Animali Esotici, Centro Veterinario Specialistico, Via Sandro Giovannini 53, Rome, Italy.

Asian palm civets (Paradoxurus hermaphroditus), or toddy cats, belong to the family Viverridae. Little is known about the pathology of these animals and few articles have been published, mainly concerning their important role as wild reservoir hosts for severe infectious diseases of domestic animals and human beings. A 4-year-old, female Asian palm civet was found dead by the owner. At necropsy, large amount of adipose tissue was found in the subcutis and in the peritoneal cavity. Most of the pancreas appeared red, translucent. Hepatomegaly, discoloration of the liver were evident, with multifocal areas of degeneration, characterized by white nodular lesions. Histologically, the pancreas showed severe interstitial and perilobular necrosis and extensive haemorrhages, with separation of the interstitium, mild reactive inflammation at the periphery of the pancreatic lobules. Liver showed multifocal foci of vacuolar degeneration, lipidic accumulation, sometimes associated to hepatocyte necrosis. A diagnosis of acute severe hemorrhagic-necrotizing pancreatitis (or acute pancreatic necrosis) associated with pancreatic and hepatic lipidosis was made. To the best of our knowledge, this represents the first case report of acute lethal pancreatitis in an Asian palm civet. Although the exact cause of the disease remains undetermined, a hypothesis of the cause and pathogenesis is discussed, pointing out dietary indiscretion and consequent overweight as possible important risk factors.
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http://dx.doi.org/10.12980/APJTB.4.2014C915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025281PMC
May 2014

Gut microbioma population: an indicator really sensible to any change in age, diet, metabolic syndrome, and life-style.

Mediators Inflamm 2014 4;2014:901308. Epub 2014 Jun 4.

Division of Hypertension and Nephrology, Department of System Medicine, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.

Obesity has become a pandemic threat in the latest 30 years. The trend of the prevalence of overweight and obesity has got an overall increase in every part of the world, regardless of ethnicity, life-style and social ties. High food intake, genetic, and sedentary have been related to obesity; it has been also hypothesized that gut microbiota could have an impact on the complex mechanism underlying the weight gain. This review aims to illustrate the actual literature about gut microbiota and its relation with obesity and to analyze the possible implications of factors such as diet and life-style onto the composition of gut microbiota, that can lead to overweight/obesity condition.
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http://dx.doi.org/10.1155/2014/901308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066855PMC
February 2015

The ideal consultation.

Authors:
Davies Nicola

Nurs Stand 2012 Sep;27(3):61

The consulting room used to be regarded as the doctor's preserve. Not any longer. Patients are increasingly consulting nurses for advice and treatment, especially in community settings or in the patient's home.
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http://dx.doi.org/10.7748/ns.27.3.61.s56DOI Listing
September 2012

Cerebellar liponeurocytoma: an updated follow-up of a case presenting histopathological and clinically aggressive features.

Neurol India 2009 Mar-Apr;57(2):194-6

Department of Neurosurgery, University of Florence, Florence, Italy.

Cerebellar liponeurocytoma is a rare tumor recently included by World Health Organization in the classification of brain tumors as a separate clinicopathological entity separate from medulloblastoma. However, because of the rarity of the tumor, the natural history of the tumor is still not yet been defined. We report a patient with cerebellar liponeurocytoma with unusual clinical and pathological aggressive features. This patient suggests the possible existence of different histological grades of liponeurocytoma and its possible progression to a malignant grade.
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http://dx.doi.org/10.4103/0028-3886.51294DOI Listing
July 2009

Chronic subdural hematoma: results of a homogeneous series of 159 patients operated on by residents.

Neurol India 2004 Dec;52(4):475-7

Neurosurgical Clinic, University of Florence, Italy.

Aims: A series of cases with chronic subdural hematoma operated upon by residents in neurosurgery is analysed.

Materials And Methods: 159 patients treated between 1998 and 2001 were included in the study. Mean age was 76.4 years and male/female ratio was 1.7/1. The patients were classified both on admission and at discharge according to the Markwalder scale. The standard operative procedure consisted of an enlarged single burr-hole, rinsing the subdural space with iso-osmotic saline solution and insertion of a subdural drain.

Conclusion: In CSDH, operation by the residents is safe and the results are comparable to those of the major series of the literature as the surgical procedure is standardized.
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December 2004

Four diopters prism test recording in small angle esotropia: a quantitative study using a magnetic search coil.

Strabismus 1998 Jun;6(2):59-69

Department of Ophthalmology, Catholic University, Rome, Italy

PURPOSE: To determine the vergence response, if any, in a homogenous group of patients suffering from strabismus and submitted to environmental induction of retinal disparity with respect to a control group of subjects. MATERIALS AND METHODS: A series of 13 subjects was included in the present study (5 normal subjects and 8 patients suffering from small angle esotropia). The patients were evaluated in an illuminated environment where they were told to stare at a target which subtended a visual angle of 20 degrees and, successively, in the dark using a luminous stimulus which subtended a visual angle of 3.5 minutes. The vergence movements were evaluated using a four diopter base-out prism; eye movements were recorded under conditions of both binocular and monocular vision. Ocular movements were recorded by means of a magnetic search coil; the amplitude and peak velocity of the vergence movements were evaluated by computer analysis. Statistical analysis was performed using the Multiple Anova test for repeated measures. RESULTS: The data obtained in the present study demonstrate that: 1) there is a significant difference between binocular and monocular vision in both groups of subjects; however, the ocular response in the patients affected by strabismus was significantly different from that in the control group of subjects; 2) during monocular vision in the dark, the response of the strabismic patients was highly variable; 3) for both groups of subjects no significant differences were observed in the vergence response when a large-angle stimulus was employed in light conditions nor when a small-angle stimulus was utilized in a dark environment.
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http://dx.doi.org/10.1076/stra.6.2.59.662DOI Listing
June 1998

[Surgical treatment of ptosis in cases of mitochondrial myopathies and severe myasthenia].

J Fr Ophtalmol 1994 ;17(1):4-9

Institut d'Ophthalmologie, Université Catholique du Sacré-Coeur, Roma, Italie.

The authors describe various surgical treatments for ptosis due to mitochondrial myopathies and myasthenia gravis. Six patients out of ten underwent an anterior approach levator resection. Four out of ten were submitted to a brow suspension according to Fox's technique. Results and postoperative complications are examined and discussed.
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June 1994

[Changes in the spirographic values of patients with pulmonary tuberculosis hospitalized at the Phthisiology Section in Dej].

Authors:
D L Nicola

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol 1988 Apr-Jun;37(2):161-72

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January 1989

A neoplasm of globule leukocytes in a cat.

Vet Pathol 1986 May;23(3):287-92

A neoplasm involving the ileo-cecal-colic junction, thymus, and tracheobronchial lymph nodes of a 7-year-old domestic cat was composed of dense sheets of round to oval mononuclear cells with oval to indented nuclei, moderate amounts of cytoplasm, and variable numbers of round eosinophilic granules. These granules are brown to black in phosphotungstic acid hematoxylin-stained sections and stain variably with the periodic acid-Schiff stain. They are 0.8 to 1.5 micron in diameter, limited by a single unit membrane, and have variable electron density. Light microscopic cellular morphology and staining characteristics as well as ultrastructural features of these cells are consistent with feline globule leukocytes. Morphologic features of the neoplastic cells in the present case are similar to those of the only other reported neoplasm of globule leukocytes which also involved the intestine of a cat.
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http://dx.doi.org/10.1177/030098588602300309DOI Listing
May 1986