Publications by authors named "Nicola Alesi"

8Publications

Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis.

Authors:

Harilaos Filippakis Amine Belaid Brian Siroky Constance Wu Nicola Alesi Thomas Hougard Julie Nijmeh Hilaire C Lam Elizabeth P Henske

Sci Rep 2018 09 21;8(1):14161. Epub 2018 Sep 21.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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September 2018

TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.

Authors:

Heng-Jia Liu Patrick H Lizotte Heng Du Maria C Speranza Hilaire C Lam Spencer Vaughan Nicola Alesi Kwok-Kin Wong Gordon J Freeman Arlene H Sharpe Elizabeth P Henske

JCI Insight 2018 04 19;3(8). Epub 2018 Apr 19.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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April 2018

Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells.

Authors:

Hilaire C Lam Heng-Jia Liu Christian V Baglini Harilaos Filippakis Nicola Alesi Julie Nijmeh Heng Du Alicia Llorente Lope Katherine A Cottrill Adam Handen John M Asara David J Kwiatkowski Issam Ben-Sahra William M Oldham Stephen Y Chan Elizabeth P Henske

Oncotarget 2017 Sep 4;8(39):64714-64727. Epub 2017 Aug 4.

Department of Medicine, Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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September 2017

p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.

Cancer Res 2017 06 16;77(12):3255-3267. Epub 2017 May 16.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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June 2017

Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R.

Authors:

Harilaos Filippakis Nicola Alesi Barbara Ogorek Julie Nijmeh Damir Khabibullin Catherine Gutierrez Alexander J Valvezan James Cunningham Carmen Priolo Elizabeth P Henske

Oncotarget 2017 Jun;8(24):38099-38112

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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June 2017

Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development.

Authors:

Krinio Giannikou Izabela A Malinowska Trevor J Pugh Rachel Yan Yuen-Yi Tseng Coyin Oh Jaegil Kim Magdalena E Tyburczy Yvonne Chekaluk Yang Liu Nicola Alesi Geraldine A Finlay Chin-Lee Wu Sabina Signoretti Matthew Meyerson Gad Getz Jesse S Boehm Elizabeth P Henske David J Kwiatkowski

PLoS Genet 2016 08 5;12(8):e1006242. Epub 2016 Aug 5.

Division of Pulmonary and Critical Care Medicine and of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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August 2016

Clinical pharmacogenetics of methotrexate.

Authors:

Pasqualina Castaldo Simona Magi Annamaria Assunta Nasti Sara Arcangeli Vincenzo Lariccia Nicola Alesi Massimo Tocchini Salvatore Amoroso

Curr Drug Metab 2011 Mar;12(3):278-86

Department of Neuroscience, Unit of Pharmacology, School of Medicine, University Politecnica delle Marche, Ancona, Italy.

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March 2011