Publications by authors named "Nicki Tiffin"

45Publications

Incident tuberculosis disease in patients receiving biologic therapies in the Western Cape, South Africa from 2007 to 2018.

BMC Infect Dis 2020 Nov 30;20(1):900. Epub 2020 Nov 30.

Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, Republic of South Africa.

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November 2020

Equitable Science Requires Collegial Debate.

Trends Biotechnol 2021 Feb 19;39(2):112. Epub 2020 Nov 19.

University of Cape Town, Cape Town, South Africa.

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February 2021

Risk factors for COVID-19 death in a population cohort study from the Western Cape Province, South Africa.

Authors:
Andrew Boulle Mary-Ann Davies Hannah Hussey Muzzammil Ismail Erna Morden Ziyanda Vundle Virginia Zweigenthal Hassan Mahomed Masudah Paleker David Pienaar Yamanya Tembo Charlene Lawrence Washiefa Isaacs Hlengani Mathema Derick Allen Taryn Allie Jamy-Lee Bam Kasturi Buddiga Pierre Dane Alexa Heekes Boitumelo Matlapeng Themba Mutemaringa Luckmore Muzarabani Florence Phelanyane Rory Pienaar Catherine Rode Mariette Smith Nicki Tiffin Nesbert Zinyakatira Carol Cragg Frederick Marais Vanessa Mudaly Jacqueline Voget Jody Davids Francois Roodt Nellis van Zyl Smit Alda Vermeulen Kevin Adams Gordon Audley Kathleen Bateman Peter Beckwith Marc Bernon Dirk Blom Linda Boloko Jean Botha Adam Boutall Sean Burmeister Lydia Cairncross Gregory Calligaro Cecilia Coccia Chadwin Corin Remy Daroowala Joel A Dave Elsa De Bruyn Martin De Villiers Mimi Deetlefs Sipho Dlamini Thomas Du Toit Wilhelm Endres Tarin Europa Graham Fieggan Anthony Figaji Petro Frankenfeld Elizabeth Gatley Phindile Gina Evashan Govender Rochelle Grobler Manqoba Vusumuzi Gule Christoff Hanekom Michael Held Alana Heynes Sabelo Hlatswayo Bridget Hodkinson Jeanette Holtzhausen Shakeel Hoosain Ashely Jacobs Miriam Kahn Thania Kahn Arvin Khamajeet Joubin Khan Riaasat Khan Alicia Khwitshana Lauren Knight Sharita Kooverjee Rene Krogscheepers Jean Jacque Kruger Suzanne Kuhn Kim Laubscher John Lazarus Jacque Le Roux Scott Lee Jones Dion Levin Gary Maartens Thina Majola Rodgers Manganyi David Marais Suzaan Marais Francois Maritz Deborah Maughan Simthandile Mazondwa Luyanda Mbanga Nomonde Mbatani Bulewa Mbena Graeme Meintjes Marc Mendelson Ernst Möller Allison Moore Babalwa Ndebele Marc Nortje Ntobeko Ntusi Funeka Nyengane Chima Ofoegbu Nectarios Papavarnavas Jonny Peter Henri Pickard Kent Pluke Peter J Raubenheimer Gordon Robertson Julius Rozmiarek A Sayed Matthias Scriba Hennie Sekhukhune Prasun Singh Elsabe Smith Vuyolwethu Soldati Cari Stek Robert van den Berg Le Roux van der Merwe Pieter Venter Barbra Vermooten Gerrit Viljoen Santhuri Viranna Jonno Vogel Nokubonga Vundla Sean Wasserman Eddy Zitha Vanessa Lomas-Marais Annie Lombard Katrin Stuve Werner Viljoen De Vries Basson Sue Le Roux Ethel Linden-Mars Lizanne Victor Mark Wates Elbe Zwanepoel Nabilah Ebrahim Sa'ad Lahri Ayanda Mnguni Thomas Crede Martin de Man Katya Evans Clint Hendrikse Jonathan Naude Moosa Parak Patrick Szymanski Candice Van Koningsbruggen Riezaah Abrahams Brian Allwood Christoffel Botha Matthys Henndrik Botha Alistair Broadhurst Dirkie Claasen Che Daniel Riyaadh Dawood Marie du Preez Nicolene Du Toit Kobie Erasmus Coenraad F N Koegelenberg Shiraaz Gabriel Susan Hugo Thabiet Jardine Clint Johannes Sumanth Karamchand Usha Lalla Eduard Langenegger Eize Louw Boitumelo Mashigo Nonte Mhlana Chizama Mnqwazi Ashley Moodley Desiree Moodley Saadiq Moolla Abdurasiet Mowlana Andre Nortje Elzanne Olivier Arifa Parker Chané Paulsen Hans Prozesky Jacques Rood Tholakele Sabela Neshaad Schrueder Nokwanda Sithole Sthembiso Sithole Jantjie J Taljaard Gideon Titus Tian Van Der Merwe Marije van Schalkwyk Luthando Vazi Abraham J Viljoen Mogamat Yazied Chothia Vanessa Naidoo Lee Alan Wallis Mumtaz Abbass Juanita Arendse Rizqa Armien Rochelle Bailey Muideen Bello Rachel Carelse Sheron Forgus Nosi Kalawe Saadiq Kariem Mariska Kotze Jonathan Lucas Juanita McClaughlin Kathleen Murie Leilah Najjaar Liesel Petersen James Porter Melanie Shaw Dusica Stapar Michelle Williams Linda Aldum Natacha Berkowitz Raakhee Girran Kevin Lee Lenny Naidoo Caroline Neumuller Kim Anderson Kerrin Begg Lisa Boerlage Morna Cornell Renée de Waal Lilian Dudley René English Jonathan Euvrard Pam Groenewald Nisha Jacob Heather Jaspan Emma Kalk Naomi Levitt Thoko Malaba Patience Nyakato Gabriela Patten Helen Schneider Maylene Shung King Priscilla Tsondai James Van Duuren Nienke van Schaik Lucille Blumberg Cheryl Cohen Nelesh Govender Waasila Jassat Tendesayi Kufa Kerrigan McCarthy Lynn Morris Nei-Yuan Hsiao Ruan Marais Jon Ambler Olina Ngwenya Richard Osei-Yeboah Leigh Johnson Reshma Kassanjee Tsaone Tamuhla

Clin Infect Dis 2020 Aug 29. Epub 2020 Aug 29.

Division of Computational Biology, University of Cape Town.

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August 2020

Patient-centric research in the time of COVID-19: conducting ethical COVID-19 research in Africa.

BMJ Glob Health 2020 08;5(8)

Wellcome Centre for Infectious Disease Research in Africa, University of Cape Town, Cape Town, South Africa

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August 2020

Does having a mobile phone matter? Linking phone access among women to health in India: An exploratory analysis of the National Family Health Survey.

PLoS One 2020 20;15(7):e0236078. Epub 2020 Jul 20.

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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September 2020

Including Digital Sequence Data in the Nagoya Protocol Can Promote Data Sharing.

Trends Biotechnol 2021 Feb 10;39(2):116-125. Epub 2020 Jul 10.

Computational Biology Division, University of Cape Town, Cape Town, South Africa; Wellcome Centre for Infectious Disease Research in Africa, University of Cape Town, Cape Town, South Africa; Centre for Infectious Disease Epidemiology Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa. Electronic address:

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February 2021

Potential risks and solutions for sharing genome summary data from African populations.

Authors:
Nicki Tiffin

BMC Med Genomics 2019 11 4;12(1):152. Epub 2019 Nov 4.

Computational Biology Division, Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.

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November 2019

A framework for tiered informed consent for health genomic research in Africa.

Nat Genet 2019 11;51(11):1566-1571

Department of Integrative Biomedical Sciences, Computational Biology Division, University of Cape Town, Cape Town, South Africa.

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November 2019

How to use relevant data for maximal benefit with minimal risk: digital health data governance to protect vulnerable populations in low-income and middle-income countries.

BMJ Glob Health 2019 11;4(2):e001395. Epub 2019 Apr 11.

Division of Epidemiology and Biostatistics, Public Health and Family Medicine, University of Cape Town, Rondebosch, South Africa.

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April 2019

Use of Big Data and Machine Learning Methods in the Monitoring and Evaluation of Digital Health Programs in India: An Exploratory Protocol.

JMIR Res Protoc 2019 May 24;8(5):e11456. Epub 2019 May 24.

Department of International Health, Global Disease Epidemiology & Control Program, Johns Hopkins Bloomberg School Public Health, Baltimore, MD, United States.

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May 2019

Tiered informed consent: respecting autonomy, agency and individuality in Africa.

Authors:
Nicki Tiffin

BMJ Glob Health 2018 17;3(6):e001249. Epub 2018 Dec 17.

Wellcome Centre for Infectious Disease Research in Africa, University of Cape Town, Cape Town, South Africa.

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December 2018

Delineation of the HPV11E6 and HPV18E6 Pathways in Initiating Cellular Transformation.

Front Oncol 2017 1;7:258. Epub 2017 Nov 1.

Faculty of Health Sciences, Division of Medical Biochemistry and Structural Biology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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November 2017

A meta-analysis of public microarray data identifies gene regulatory pathways deregulated in peripheral blood mononuclear cells from individuals with Systemic Lupus Erythematosus compared to those without.

BMC Med Genomics 2016 11 15;9(1):66. Epub 2016 Nov 15.

South African National Bioinformatics Institute/Medical Research Council of South Africa Bioinformatics Capacity Development Unit, University of the Western Cape, Cape Town, South Africa.

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November 2016

NetCapDB: measuring bioinformatics capacity development in Africa.

BMC Res Notes 2016 Mar 5;9:144. Epub 2016 Mar 5.

South African National Bioinformatics Institute/Medical Research Council of South Africa Bioinformatics Unit, University of the Western Cape, Cape Town, South Africa.

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March 2016

The Development of Computational Biology in South Africa: Successes Achieved and Lessons Learnt.

PLoS Comput Biol 2016 Feb 4;12(2):e1004395. Epub 2016 Feb 4.

South African National Bioinformatics Institute/Medical Research Council of South Africa Bioinformatics Unit, University of the Western Cape, Bellville, South Africa.

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February 2016

Human Heredity and Health (H3) in Africa Kidney Disease Research Network: A Focus on Methods in Sub-Saharan Africa.

Clin J Am Soc Nephrol 2015 Dec 2;10(12):2279-87. Epub 2015 Jul 2.

Departments of Pediatrics and Medicine, Hospital for Sick Children, University of Health Network, University of Toronto, Toronto, Ontario, Canada.

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December 2015

Informed consent and ethical re-use of African genomic data.

Hum Genomics 2014 Oct 22;8:18. Epub 2014 Oct 22.

South African National Bioinformatics Institute/Medical Research Council of South Africa Bioinformatics Unit, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africa.

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October 2014

Research capacity. Enabling the genomic revolution in Africa.

Authors:
Charles Rotimi Akin Abayomi Alash'le Abimiku Victoria May Adabayeri Clement Adebamowo Ezekiel Adebiyi Adebowale D Ademola Adebowale Adeyemo Dwomoa Adu Dissou Affolabi Godfred Agongo Samuel Ajayi Sally Akarolo-Anthony Rufus Akinyemi Albert Akpalu Marianne Alberts Orlando Alonso Betancourt Ahmed Mansour Alzohairy Gobena Ameni Olukemi Amodu Gabriel Anabwani Kristian Andersen Fatiu Arogundade Oyedunni Arulogun Danny Asogun Rasheed Bakare Naby Balde Mary Lynn Baniecki Christine Beiswanger Alia Benkahla Lara Bethke Micheal Boehnke Vincent Boima James Brandful Andrew I Brooks Frank C Brosius Chester Brown Bruno Bucheton David T Burke Barrington G Burnett Stacy Carrington-Lawrence Nadia Carstens John Chisi Alan Christoffels Richard Cooper Heather Cordell Nigel Crowther Talishiea Croxton Jantina de Vries Leslie Derr Peter Donkor Seydou Doumbia Audrey Duncanson Ivy Ekem Ahmed El Sayed Mark E Engel John C K Enyaru Dean Everett Faisal M Fadlelmola Eyitayo Fakunle Kenneth H Fischbeck Anne Fischer Onikepe Folarin Junaid Gamieldien Robert F Garry Simani Gaseitsiwe Rasheed Gbadegesin Anita Ghansah Maria Giovanni Parham Goesbeck F Xavier Gomez-Olive Donald S Grant Ravnit Grewal Mark Guyer Neil A Hanchard Christian T Happi Scott Hazelhurst Branwen J Hennig Christiane Hertz- Fowler Winston Hide Friedhelm Hilderbrandt Christopher Hugo-Hamman Muntaser E Ibrahim Regina James Yasmina Jaufeerally-Fakim Carolyn Jenkins Ute Jentsch Pan-Pan Jiang Moses Joloba Victor Jongeneel Fourie Joubert Mukthar Kader Kathleen Kahn Pontiano Kaleebu Saidi H Kapiga Samar Kamal Kassim Ishmael Kasvosve Jonathan Kayondo Bernard Keavney Adeodata Kekitiinwa Sheik Humarr Khan Paul Kimmel Mary-Claire King Robert Kleta Mathurin Koffi Jeffrey Kopp Matthias Kretzler Judit Kumuthini Samuel Kyobe Catherine Kyobutungi Daniel T Lackland Karen A Lacourciere Guida Landouré Rita Lawlor Thomas Lehner Maia Lesosky Naomi Levitt Katherine Littler Zane Lombard Jeanne F Loring Sylvester Lyantagaye Annette Macleod Ebony B Madden Chengetai R Mahomva Julie Makani Manmak Mamven Marape Marape Graeme Mardon Patricia Marshall Darren P Martin Daniel Masiga Robin Mason Michael Mate-Kole Enock Matovu Mary Mayige Bongani M Mayosi Jean Claude Mbanya Sheryl A McCurdy Mark I McCarthy Helen McIlleron S O Mc'Ligeyo Corrine Merle Ana Olga Mocumbi Charles Mondo John V Moran Ayesha Motala Marva Moxey-Mims Wata Sununguko Mpoloka Chisomo L Msefula Thuli Mthiyane Nicola Mulder Gebregziab her Mulugeta Dieuodonne Mumba John Musuku Mo Nagdee Oyekanmi Nash Daouda Ndiaye Anh Quynh Nguyen Mark Nicol Oathokwa Nkomazana Shane Norris Betty Nsangi Alexander Nyarko Moffat Nyirenda Eileen Obe Reginald Obiakor Abraham Oduro Solomon F Ofori-Acquah Okechukwu Ogah Stephen Ogendo Kwaku Ohene-Frempong Akinlolu Ojo Timothy Olanrewaju John Oli Charlotte Osafo Odile Ouwe Missi Oukem-Boyer Bruce Ovbiagele Andrew Owen Mayowa Ojo Owolabi Lukman Owolabi Ellis Owusu-Dabo Guillaume Pare Rulan Parekh Hugh G Patterton Margaret B Penno Jane Peterson Rembert Pieper Jacob Plange-Rhule Martin Pollak Julia Puzak Rajkumar S Ramesar Michele Ramsay Rebekah Rasooly Shiksha Reddy Pardis C Sabeti Kwamena Sagoe Tunde Salako Oumar Samassékou Manjinder S Sandhu Osman Sankoh Fred Stephen Sarfo Marie Sarr Gasnat Shaboodien Issa Sidibe Gustave Simo Martin Simuunza Liam Smeeth Eugene Sobngwi Himla Soodyall Hermann Sorgho Oumou Sow Bah Sudha Srinivasan Dan J Stein Ezra S Susser Carmen Swanepoel Godfred Tangwa Andrew Tareila Ozlem Tastan Bishop Bamidele Tayo Nicki Tiffin Halidou Tinto Ekaete Tobin Stephen Meir Tollman Mahamadou Traoré Marsha J Treadwell Jennifer Troyer Masego Tsimako-Johnstone Vincent Tukei Ifeoma Ulasi Nzovu Ulenga Beverley van Rooyen Ablo Prudence Wachinou Salina P Waddy Alisha Wade Misaki Wayengera James Whitworth Louise Wideroff Cheryl A Winkler Sarah Winnicki Ambroise Wonkam Mengistu Yewondwos Tadase sen Nathan Yozwiak Heather Zar

Science 2014 Jun;344(6190):1346-8

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June 2014

Unique considerations for advancing genomic medicine in African populations.

Authors:
Nicki Tiffin

Per Med 2014 Mar;11(2):187-196

South African National Bioinformatics Institute/SA Medical Research Council Bioinformatics Unit, University of the Western Cape, Cape Town, Western Cape, South Africa.

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March 2014

Ethical and legal implications of whole genome and whole exome sequencing in African populations.

BMC Med Ethics 2013 May 28;14:21. Epub 2013 May 28.

South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa.

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May 2013

A diverse array of genetic factors contribute to the pathogenesis of systemic lupus erythematosus.

Orphanet J Rare Dis 2013 Jan 7;8. Epub 2013 Jan 7.

South African National Bioinformatics Institute/MRC Unit for Bioinformatics Capacity Development, University of the Western Cape, Private Bag X17, Bellville, Cape Town 7535, South Africa.

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January 2013

Conceptual thinking for in silico prioritization of candidate disease genes.

Authors:
Nicki Tiffin

Methods Mol Biol 2011 ;760:175-87

The South African National Bioinformatics Institute, University of the Western Cape, 7925, Belville, Cape Town, South Africa.

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November 2011

Computational analysis of candidate disease genes and variants for salt-sensitive hypertension in indigenous Southern Africans.

PLoS One 2010 Sep 27;5(9):e12989. Epub 2010 Sep 27.

Division of Nephrology and Hypertension, University of Cape Town/Groote Schuur Hospital, Cape Town, South Africa.

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September 2010

Linking genes to diseases: it's all in the data.

Genome Med 2009 Aug 7;1(8):77. Epub 2009 Aug 7.

MRC/UWC/SANBI Bioinformatics Capacity Development Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville 7535, South Africa.

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August 2009

Prioritization of candidate disease genes for metabolic syndrome by computational analysis of its defining phenotypes.

Physiol Genomics 2008 Sep 8;35(1):55-64. Epub 2008 Jul 8.

Division of Human Genetics, MRC Human Genetics Research Unit, Institute for Infectious Diseases and Molecular Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

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September 2008

Computational selection and prioritization of candidate genes for fetal alcohol syndrome.

BMC Genomics 2007 Oct 25;8:389. Epub 2007 Oct 25.

Division of Human Genetics, National Health Laboratory Service & School of Pathology, University of the Witwatersrand, Johannesburg, 2001, South Africa.

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October 2007

Integration of text- and data-mining using ontologies successfully selects disease gene candidates.

Nucleic Acids Res 2005 14;33(5):1544-52. Epub 2005 Mar 14.

South African National Bioinformatics Institute, University of the Western Cape Belville 7535, South Africa.

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March 2005

WT1 expression does not disrupt myogenic differentiation in C2C12 murine myoblasts or in human rhabdomyosarcoma.

Exp Cell Res 2003 Jul;287(1):155-65

Section of Paediatric Oncology, Institute of Cancer Research, 15 Cotswold Road, Belmont, Sutton, SM2 5NG, Surrey, UK.

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July 2003