Publications by authors named "Nichollas E Scott"

66Publications

2020 FASEB Science Research Conference on Microbial Glycobiology, July 13-14, 2020.

FASEB J 2020 Oct 8. Epub 2020 Oct 8.

Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.

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http://dx.doi.org/10.1096/fj.202002191DOI Listing
October 2020

The Effector SseK3 Targets Small Rab GTPases.

Front Cell Infect Microbiol 2020 19;10:419. Epub 2020 Aug 19.

Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.

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http://dx.doi.org/10.3389/fcimb.2020.00419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466453PMC
August 2020

Open Database Searching Enables the Identification and Comparison of Bacterial Glycoproteomes without Defining Glycan Compositions Prior to Searching.

Mol Cell Proteomics 2020 09 23;19(9):1561-1574. Epub 2020 Jun 23.

Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia

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http://dx.doi.org/10.1074/mcp.TIR120.002100DOI Listing
September 2020

Trefoil factors share a lectin activity that defines their role in mucus.

Nat Commun 2020 05 13;11(1):2265. Epub 2020 May 13.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1038/s41467-020-16223-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221086PMC
May 2020

An intra-bacterial activity for a T3SS effector.

Sci Rep 2020 01 23;10(1):1073. Epub 2020 Jan 23.

College of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA.

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http://dx.doi.org/10.1038/s41598-020-58062-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978387PMC
January 2020

Biogenesis of the Spacious -Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3.

Infect Immun 2020 02 20;88(3). Epub 2020 Feb 20.

Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia

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http://dx.doi.org/10.1128/IAI.00534-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035922PMC
February 2020

Low pH Exposure During Immunoglobulin G Purification Methods Results in Aggregates That Avidly Bind Fcγ Receptors: Implications for Measuring Fc Dependent Antibody Functions.

Front Immunol 2019 11;10:2415. Epub 2019 Oct 11.

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2019.02415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797627PMC
October 2019

Peptidyl-Prolyl Isomerase Is Essential for Proteome Homeostasis and Virulence in Burkholderia pseudomallei.

Infect Immun 2019 10 19;87(10). Epub 2019 Sep 19.

Marshall Center for Infectious Diseases Research and Training, School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia

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http://dx.doi.org/10.1128/IAI.00528-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759293PMC
October 2019

Expanding our understanding of the role of microbial glycoproteomes through high-throughput mass spectrometry approaches.

Glycoconj J 2019 08 4;36(4):259-266. Epub 2019 Jul 4.

Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.

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http://dx.doi.org/10.1007/s10719-019-09875-1DOI Listing
August 2019

Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways.

Mol Cell Proteomics 2019 06 22;18(6):1138-1156. Epub 2019 Mar 22.

From the ‡Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia;

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http://dx.doi.org/10.1074/mcp.RA118.001093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553940PMC
June 2019

Characterization of the Citrobacter rodentium Cpx regulon and its role in host infection.

Mol Microbiol 2019 03 11;111(3):700-716. Epub 2019 Feb 11.

Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/mmi.14182
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http://dx.doi.org/10.1111/mmi.14182DOI Listing
March 2019

Protein -fucosyltransferase 2-mediated -glycosylation of the adhesin MIC2 is dispensable for tachyzoite infection.

J Biol Chem 2019 02 4;294(5):1541-1553. Epub 2018 Dec 4.

the Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria 3010, Australia

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http://www.jbc.org/lookup/doi/10.1074/jbc.RA118.005357
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http://dx.doi.org/10.1074/jbc.RA118.005357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364784PMC
February 2019

Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells.

Sci Rep 2018 11 26;8(1):17353. Epub 2018 Nov 26.

Department of Biochemistry and Molecular Biology, Life Sciences Institute, University of British Columbia, Vancouver BC, V6T 1Z3, Canada.

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http://www.nature.com/articles/s41598-018-35717-5
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http://dx.doi.org/10.1038/s41598-018-35717-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255767PMC
November 2018

Surface Exposure and Packing of Lipoproteins into Outer Membrane Vesicles Are Coupled Processes in .

mSphere 2018 11 7;3(6). Epub 2018 Nov 7.

Department of Molecular Microbiology, Washington University in Saint Louis, Saint Louis, Missouri, USA

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http://msphere.asm.org/lookup/doi/10.1128/mSphere.00559-18
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http://dx.doi.org/10.1128/mSphere.00559-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222051PMC
November 2018

Synthesis and use of 6,6,6-trifluoro-L-fucose to block core-fucosylation in hybridoma cell lines.

Carbohydr Res 2018 07 23;465:4-9. Epub 2018 May 23.

ACRF Chemical Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00086215183023
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http://dx.doi.org/10.1016/j.carres.2018.05.008DOI Listing
July 2018

Post-translational Mechanisms of Host Subversion by Bacterial Effectors.

Trends Mol Med 2017 12 14;23(12):1088-1102. Epub 2017 Nov 14.

Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton 3168, Australia; Department of Molecular and Translational Science, Monash University, Clayton 3168, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714914173018
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http://dx.doi.org/10.1016/j.molmed.2017.10.003DOI Listing
December 2017

A rapid and accurate approach for prediction of interactomes from co-elution data (PrInCE).

BMC Bioinformatics 2017 Oct 23;18(1):457. Epub 2017 Oct 23.

Michael Smith Laboratories, University of British Columbia, Vancouver, V6T 1Z4, Canada.

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http://dx.doi.org/10.1186/s12859-017-1865-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654062PMC
October 2017

The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD).

J Biol Chem 2017 10 31;292(42):17337-17350. Epub 2017 Aug 31.

From the Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia.

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http://dx.doi.org/10.1074/jbc.M117.805036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655511PMC
October 2017

The role of mass spectrometry analysis in bacterial effector characterization.

Biochem J 2017 08 7;474(16):2779-2784. Epub 2017 Aug 7.

Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia

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http://dx.doi.org/10.1042/BCJ20160797DOI Listing
August 2017

Pathogenic species have a functional type I secretion system and contact-dependent inhibition systems.

J Biol Chem 2017 06 3;292(22):9075-9087. Epub 2017 Apr 3.

From the Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110,

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http://dx.doi.org/10.1074/jbc.M117.781575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454093PMC
June 2017

Interactome disassembly during apoptosis occurs independent of caspase cleavage.

Mol Syst Biol 2017 01 12;13(1):906. Epub 2017 Jan 12.

Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293159PMC
http://dx.doi.org/10.15252/msb.20167067DOI Listing
January 2017

Characterizing Glycoproteins by Mass Spectrometry in Campylobacter jejuni.

Methods Mol Biol 2017 ;1512:211-232

Department of Microbiology and Immunology, Doherty Institute, The University of Melbourne, 792 Elizabeth St., Melbourne, Victoria, 3001, Australia.

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http://dx.doi.org/10.1007/978-1-4939-6536-6_18DOI Listing
January 2018

The Type III Effector NleD from Enteropathogenic Escherichia coli Differentiates between Host Substrates p38 and JNK.

Infect Immun 2017 02 26;85(2). Epub 2017 Jan 26.

Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia

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http://dx.doi.org/10.1128/IAI.00620-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278161PMC
February 2017

Protein O-linked glycosylation in the plant pathogen Ralstonia solanacearum.

Glycobiology 2016 Mar 3;26(3):301-11. Epub 2015 Nov 3.

Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada Department of Molecular Microbiology, Washington University School of Medicine St. Louis, St. Louis, MO, USA

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http://dx.doi.org/10.1093/glycob/cwv098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736539PMC
March 2016

High-Frequency Variation of Purine Biosynthesis Genes Is a Mechanism of Success in Campylobacter jejuni.

mBio 2015 Sep 29;6(5):e00612-15. Epub 2015 Sep 29.

Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

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http://dx.doi.org/10.1128/mBio.00612-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611032PMC
September 2015

Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation.

Nat Struct Mol Biol 2015 Aug 20;22(8):627-35. Epub 2015 Jul 20.

1] Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada. [2] Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.

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http://www.nature.com/articles/nsmb.3060
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http://dx.doi.org/10.1038/nsmb.3060DOI Listing
August 2015

Novel Host Proteins and Signaling Pathways in Enteropathogenic E. coli Pathogenesis Identified by Global Phosphoproteome Analysis.

Mol Cell Proteomics 2015 Jul 5;14(7):1927-45. Epub 2015 May 5.

From the ‡Michael Smith Laboratories and **Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada, and ¶¶Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada

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http://dx.doi.org/10.1074/mcp.M114.046847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587332PMC
July 2015

Enrichment and identification of bacterial glycopeptides by mass spectrometry.

Methods Mol Biol 2015 ;1295:355-68

School of Molecular Bioscience, The University of Sydney, Sydney, NSW, 2006, Australia.

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http://dx.doi.org/10.1007/978-1-4939-2550-6_25DOI Listing
December 2015

Clinical implications of glycoproteomics for Acinetobacter baumannii.

Expert Rev Proteomics 2015 Feb 11;12(1):1-3. Epub 2014 Dec 11.

University of Alberta, Biological Sciences, Edmonton, AB, Canada.

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http://dx.doi.org/10.1586/14789450.2015.987756DOI Listing
February 2015

Development of a computational framework for the analysis of protein correlation profiling and spatial proteomics experiments.

J Proteomics 2015 Apr 20;118:112-29. Epub 2014 Nov 20.

Centre for High-throughput Biology, University of British Columbia, Vancouver V6T 1Z4, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.10.024DOI Listing
April 2015

Comparative proteomics and glycoproteomics reveal increased N-linked glycosylation and relaxed sequon specificity in Campylobacter jejuni NCTC11168 O.

J Proteome Res 2014 Nov 25;13(11):5136-50. Epub 2014 Aug 25.

School of Molecular Bioscience and ‡Charles Perkins Centre, The University of Sydney , Sydney, New South Wales 2006, Australia.

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http://dx.doi.org/10.1021/pr5005554DOI Listing
November 2014

Diversity within the O-linked protein glycosylation systems of acinetobacter species.

Mol Cell Proteomics 2014 Sep 10;13(9):2354-70. Epub 2014 Jun 10.

§Alberta Glycomics Centre and Department of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2E9, Canada;

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http://dx.doi.org/10.1074/mcp.M114.038315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159654PMC
September 2014

A general protein O-glycosylation system within the Burkholderia cepacia complex is involved in motility and virulence.

Mol Microbiol 2014 Apr 5;92(1):116-37. Epub 2014 Mar 5.

Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada, T6G 2E9.

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http://dx.doi.org/10.1111/mmi.12540DOI Listing
April 2014

Site-specific glycan-peptide analysis for determination of N-glycoproteome heterogeneity.

J Proteome Res 2013 Dec 1;12(12):5791-800. Epub 2013 Nov 1.

Discipline of Pathology, School of Medical Sciences, The University of Sydney , Sydney 2006, Australia.

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http://dx.doi.org/10.1021/pr400783jDOI Listing
December 2013

Secretome of transmissible Pseudomonas aeruginosa AES-1R grown in a cystic fibrosis lung-like environment.

J Proteome Res 2013 Dec 9;12(12):5357-69. Epub 2013 Oct 9.

School of Molecular Bioscience, The University of Sydney , Building GO8, Maze Crescent, Sydney, New South Wales 2006, Australia.

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http://pubs.acs.org/doi/10.1021/pr4007365
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http://dx.doi.org/10.1021/pr4007365DOI Listing
December 2013

A common pathway for O-linked protein-glycosylation and synthesis of capsule in Acinetobacter baumannii.

Mol Microbiol 2013 Sep 12;89(5):816-30. Epub 2013 Jul 12.

Alberta Glycomics Centre, Department of Biological Sciences, University of Alberta, CW405 Biological Sciences Building, Edmonton, Alberta, Canada, T6G 2E9.

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http://dx.doi.org/10.1111/mmi.12300DOI Listing
September 2013

In vitro activity of Neisseria meningitidis PglL O-oligosaccharyltransferase with diverse synthetic lipid donors and a UDP-activated sugar.

J Biol Chem 2013 Apr 4;288(15):10578-87. Epub 2013 Mar 4.

Alberta Glycomics Centre, Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada.

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http://dx.doi.org/10.1074/jbc.M112.432815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624439PMC
April 2013

Modification of the Campylobacter jejuni N-linked glycan by EptC protein-mediated addition of phosphoethanolamine.

J Biol Chem 2012 Aug 2;287(35):29384-96. Epub 2012 Jul 2.

School of Molecular Bioscience, and Discipline of Pathology (School of Medical Sciences), The University of Sydney, Australia 2006.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.380212
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http://dx.doi.org/10.1074/jbc.M112.380212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436159PMC
August 2012

Campylobacter proteomics: guidelines, challenges and future perspectives.

Expert Rev Proteomics 2009 Feb;6(1):61-74

School of Molecular and Microbial Biosciences, Building GO8, Maze Crescent, The University of Sydney, Australia.

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http://dx.doi.org/10.1586/14789450.6.1.61DOI Listing
February 2009

Identification of membrane-associated proteins from Campylobacter jejuni strains using complementary proteomics technologies.

Proteomics 2008 Jan;8(1):122-39

School of Molecular and Microbial Biosciences, The University of Sydney, Sydney, New South Wales, NSW 2006, Australia.

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http://dx.doi.org/10.1002/pmic.200700561DOI Listing
January 2008