Nicholas P Tatonetti

Nicholas P Tatonetti

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Nicholas P Tatonetti

Nicholas P Tatonetti

Publications by authors named "Nicholas P Tatonetti"

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No Increased Risk of Colorectal Adenomas in Spouses of Patients with Colorectal Neoplasia.

Clin Gastroenterol Hepatol 2020 Feb 27;18(2):509-510. Epub 2019 Mar 27.

Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Medical Center, New York, New York; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.

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http://dx.doi.org/10.1016/j.cgh.2019.03.038DOI Listing
February 2020

Low Screening Rates for Diabetes Mellitus Among Family Members of Affected Relatives.

AMIA Annu Symp Proc 2018 5;2018:1471-1477. Epub 2018 Dec 5.

Value Institute, NewYork-Presbyterian Hospital, New York, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371358PMC
January 2020

Precision Medicine: Addressing the Challenges of Sharing, Analysis, and Privacy at Scale.

Pac Symp Biocomput 2020 ;25:547-550

University of California, Berkeley, USA.

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January 2020

Molecular nephrology: types of acute tubular injury.

Nat Rev Nephrol 2019 Oct 22;15(10):599-612. Epub 2019 Aug 22.

Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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http://dx.doi.org/10.1038/s41581-019-0184-xDOI Listing
October 2019

Pathway analysis of genomic pathology tests for prognostic cancer subtyping.

J Biomed Inform 2019 Oct 6;98:103286. Epub 2019 Sep 6.

Department of Biomedical Informatics, Columbia University, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jbi.2019.103286DOI Listing
October 2019

Artificial Intelligence for Drug Toxicity and Safety.

Trends Pharmacol Sci 2019 Sep 2;40(9):624-635. Epub 2019 Aug 2.

Columbia University Medical Center, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2019.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710127PMC
September 2019

Informatics and Computational Methods in Natural Product Drug Discovery: A Review and Perspectives.

Front Genet 2019 30;10:368. Epub 2019 Apr 30.

Department of Biomedical Informatics, Columbia University, New York, NY, United States.

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http://dx.doi.org/10.3389/fgene.2019.00368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503039PMC
April 2019

ROMOP: a light-weight R package for interfacing with OMOP-formatted electronic health record data.

JAMIA Open 2019 Apr 4;2(1):10-14. Epub 2019 Jan 4.

Department of Pediatrics Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1093/jamiaopen/ooy059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800657PMC
April 2019

Translational medicine in the Age of Big Data.

Brief Bioinform 2019 03;20(2):457-462

Departments of Biomedical Informatics, Systems Biology, and Medicine, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1093/bib/bbx116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433900PMC
March 2019

Attention Deficit-Hyperactivity Disorder and Month of School Enrollment.

N Engl J Med 2019 02;380(7):692-3

Columbia University Medical Center, New York, NY

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http://dx.doi.org/10.1056/NEJMc1817539DOI Listing
February 2019

Pathogen population structure can explain hospital outbreaks.

ISME J 2018 12 25;12(12):2835-2843. Epub 2018 Jul 25.

Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY, 11794, USA.

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http://dx.doi.org/10.1038/s41396-018-0235-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246595PMC
December 2018

Columbia Open Health Data, clinical concept prevalence and co-occurrence from electronic health records.

Sci Data 2018 11 27;5:180273. Epub 2018 Nov 27.

Department of Biomedical Informatics, Columbia University, NY, USA.

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http://dx.doi.org/10.1038/sdata.2018.273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257042PMC
November 2018

Tissue-Specific Analysis of Pharmacological Pathways.

CPT Pharmacometrics Syst Pharmacol 2018 07 19;7(7):453-463. Epub 2018 Jun 19.

Departments of Biomedical Informatics, Systems Biology, and Medicine, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1002/psp4.12305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063738PMC
July 2018

Disease Heritability Inferred from Familial Relationships Reported in Medical Records.

Cell 2018 06 17;173(7):1692-1704.e11. Epub 2018 May 17.

Department of Biomedical Informatics, Columbia University, New York, NY, USA; Institute for Genomic Medicine, Columbia University, New York, NY, USA; Observational Health Data Sciences and Informatics (OHDSI), New York, NY, USA; Department of Medicine, Columbia University, New York, NY, USA; Department of Systems Biology, Columbia University, New York, NY, USA; Data Science Institute, Columbia University, New York, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183052
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http://dx.doi.org/10.1016/j.cell.2018.04.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015747PMC
June 2018

An Assessment of Family History Information Captured in an Electronic Health Record.

AMIA Annu Symp Proc 2015 5;2015:2035-42. Epub 2015 Nov 5.

NewYork-Presbyterian Hospital, New York, NY, USA; Department of Biomedical Informatics, Columbia University, New York, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765557PMC
April 2018

METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE.

Pac Symp Biocomput 2016 ;21:180-182

Department of Biomedical Informatics, Harvard Medical School, Boston, MA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167531PMC
February 2018

The Next Generation of Drug Safety Science: Coupling Detection, Corroboration, and Validation to Discover Novel Drug Effects and Drug-Drug Interactions.

Clin Pharmacol Ther 2018 02;103(2):177-179

Department of Biomedical Informatics, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1002/cpt.949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005687PMC
February 2018

Machine learning: novel bioinformatics approaches for combating antimicrobial resistance.

Curr Opin Infect Dis 2017 Dec;30(6):511-517

aDivision of Infectious Diseases, Columbia University Medical Center bDepartment of Biomedical Informatics, Columbia University, New York City, New York, USA cDepartment of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1097/QCO.0000000000000406DOI Listing
December 2017

Development of A Machine Learning Algorithm to Classify Drugs Of Unknown Fetal Effect.

Sci Rep 2017 10 9;7(1):12839. Epub 2017 Oct 9.

Department of Biomedical Informatics, Columbia University, New York, USA.

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http://dx.doi.org/10.1038/s41598-017-12943-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634437PMC
October 2017

METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH.

Pac Symp Biocomput 2017 ;22:117-119

Massachusetts General Hospital, Boston, MA, USA2Broad Institute, Cambridge, MA, USA,

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http://dx.doi.org/10.1142/9789813207813_0012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984201PMC
July 2017

Climate Classification is an Important Factor in Assessing Quality-of-Care Across Hospitals.

Sci Rep 2017 07 10;7(1):4948. Epub 2017 Jul 10.

Department of Biomedical Informatics, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1038/s41598-017-04708-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504082PMC
July 2017

Ten Simple Rules to Enable Multi-site Collaborations through Data Sharing.

PLoS Comput Biol 2017 01 19;13(1):e1005278. Epub 2017 Jan 19.

Department of Biomedical Informatics, Columbia University, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1005278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245793PMC
January 2017

Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms.

Wiley Interdiscip Rev Syst Biol Med 2016 Mar-Apr;8(2):104-22. Epub 2015 Nov 12.

Department of Biomedical Informatics, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1002/wsbm.1323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760887PMC
November 2016

Predicting G protein-coupled receptor downstream signaling by tissue expression.

Bioinformatics 2016 11 2;32(22):3435-3443. Epub 2016 Aug 2.

Departments of Biomedical Informatics, Systems Biology, and Medicine, Columbia University, New York, NY, 10032, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181570PMC
November 2016

Replicating Cardiovascular Condition-Birth Month Associations.

Sci Rep 2016 09 14;6:33166. Epub 2016 Sep 14.

Dept of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1498, New York, NY 10029, USA.

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http://www.nature.com/articles/srep33166
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http://dx.doi.org/10.1038/srep33166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021975PMC
September 2016

In Search of 'Birth Month Genes': Using Existing Data Repositories to Locate Genes Underlying Birth Month-Disease Relationships.

AMIA Jt Summits Transl Sci Proc 2016 20;2016:189-98. Epub 2016 Jul 20.

Department of Biomedical Informatics, Columbia University; Department of Medicine, Columbia University; Department of Systems Biology, Columbia University; Observational Health Data Sciences and Informatics, Columbia University.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001771PMC
August 2016

Using a Novel Ontology to Inform the Discovery of Therapeutic Peptides from Animal Venoms.

AMIA Jt Summits Transl Sci Proc 2016 20;2016:209-18. Epub 2016 Jul 20.

Departments of Biomedical Informatics, Systems Biology, and Medicine, Columbia University Medical Center, New York, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001765PMC
August 2016

A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient.

Sci Rep 2016 07 21;6:29387. Epub 2016 Jul 21.

Department of Biomedical Informatics, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/srep29387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954953PMC
July 2016

A Pharmacovigilance Signaling System Based on FDA Regulatory Action and Post-Marketing Adverse Event Reports.

Drug Saf 2016 06;39(6):561-75

Advera Health Analytics, Inc., 3663 N. Laughlin Road, Suite 102, Santa Rosa, CA, 95403, USA.

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http://dx.doi.org/10.1007/s40264-016-0409-xDOI Listing
June 2016

Improving condition severity classification with an efficient active learning based framework.

J Biomed Inform 2016 06 22;61:44-54. Epub 2016 Mar 22.

Department of Biomedical Informatics, Columbia University, New York, NY, USA; Department of Systems Biology, Columbia University, New York, NY, USA; Department of Medicine, Columbia University, New York, NY, USA; Observational Health Data Sciences and Informatics, Columbia University, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jbi.2016.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486916PMC
June 2016

A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors.

Cell Rep 2016 06 2;15(11):2348-56. Epub 2016 Jun 2.

Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10021, USA; Institute for Precision Medicine, Weill Cornell Medical College, New York, NY 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.05.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912004PMC
June 2016

An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval.

Drug Saf 2016 May;39(5):433-41

Department of Biomedical Informatics, Columbia University, 622 West 168th St. PH20, New York, NY, 10032, USA.

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http://dx.doi.org/10.1007/s40264-016-0393-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835515PMC
May 2016

A curated and standardized adverse drug event resource to accelerate drug safety research.

Sci Data 2016 05 10;3:160026. Epub 2016 May 10.

Center for Biomedical Informatics Research, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/sdata.2016.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872271PMC
May 2016

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling.

PLoS One 2015 12;10(6):e0129974. Epub 2015 Jun 12.

Department of Biomedical Informatics, Columbia University, New York, NY, United States of America; Department of Systems Biology, Columbia University, New York, NY, United States of America; Observational Health Data Sciences and Informatics (OHDSI), New York, NY, United States of America; Department of Medicine, Columbia University, New York, NY, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129974PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466327PMC
April 2016

Mapping the effects of drugs on the immune system.

Nat Biotechnol 2016 Jan 30;34(1):47-54. Epub 2015 Nov 30.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1038/nbt.3367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706827PMC
January 2016

A Drug Safety Rating System Based on Postmarketing Costs Associated with Adverse Events and Patient Outcomes.

J Manag Care Spec Pharm 2015 Dec;21(12):1134-43

Advera Health Analytics, 3663 N. Laughlin Rd., Ste. 102, Santa Rosa, CA 95403.

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http://dx.doi.org/10.18553/jmcp.2015.21.12.1134DOI Listing
December 2015

VenomKB, a new knowledge base for facilitating the validation of putative venom therapies.

Sci Data 2015 Nov 24;2:150065. Epub 2015 Nov 24.

Department of Biomedical Informatics, Columbia University Medical Center, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/sdata.2015.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658572PMC
November 2015

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality.

PLoS Comput Biol 2015 Oct 9;11(10):e1004506. Epub 2015 Oct 9.

Department of Systems Biology, Columbia University, New York, New York, United States of America; Department of Biomedical Informatics, Columbia University, New York, New York, United States of America; Department of Medicine, Columbia University, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599967PMC
October 2015

State of the art and development of a drug-drug interaction large scale predictor based on 3D pharmacophoric similarity.

Curr Drug Metab 2014 ;15(5):490-501

Department of Biomedical Informatics, Columbia University Medical Center, 622 West 168th St. VC5, New York, NY 10032, USA.

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http://dx.doi.org/10.2174/138920021505141126102223DOI Listing
September 2015

Birth month affects lifetime disease risk: a phenome-wide method.

J Am Med Inform Assoc 2015 Sep 2;22(5):1042-53. Epub 2015 Jun 2.

Department of Biomedical Informatics Observational Health Data Sciences and Informatics (OHDSI) Department of Systems Biology Department of Medicine, Columbia University, New York, NY, USA

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http://dx.doi.org/10.1093/jamia/ocv046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986668PMC
September 2015

A knowledge-based, automated method for phenotyping in the EHR using only clinical pathology reports.

AMIA Jt Summits Transl Sci Proc 2015 23;2015:64-8. Epub 2015 Mar 23.

Department of Biomedical Informatics, Department of Systems Biology, Department of Medicine, Columbia University, New York, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525265PMC
August 2015

Are All Vaccines Created Equal? Using Electronic Health Records to Discover Vaccines Associated With Clinician-Coded Adverse Events.

AMIA Jt Summits Transl Sci Proc 2015 23;2015:196-200. Epub 2015 Mar 23.

Department of Biomedical Informatics, Columbia University ; Department of Medicine, Columbia University ; Department of Systems Biology, Columbia University ; Observational Health Data Sciences and Informatics, Columbia University.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525221PMC
August 2015

Development and validation of a classification approach for extracting severity automatically from electronic health records.

J Biomed Semantics 2015 6;6:14. Epub 2015 Apr 6.

Department of Biomedical Informatics, Columbia University, New York, NY USA ; Observational Health Data Sciences and Informatics (OHDSI), Columbia University, 622 West 168th Street, PH-20, New York, NY USA.

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http://dx.doi.org/10.1186/s13326-015-0010-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386082PMC
April 2015

3D pharmacophoric similarity improves multi adverse drug event identification in pharmacovigilance.

Sci Rep 2015 Mar 6;5:8809. Epub 2015 Mar 6.

Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1038/srep08809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351525PMC
March 2015

STORMSeq: an open-source, user-friendly pipeline for processing personal genomics data in the cloud.

PLoS One 2014 15;9(1):e84860. Epub 2014 Jan 15.

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084860PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893165PMC
December 2014

Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors.

ChemMedChem 2014 Oct 18;9(10):2245-53. Epub 2014 Jul 18.

Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Avda. das Ciencias, 15782 Santiago de Compostela (Spain); CIQUP, Department of Chemistry & Biochemistry, Faculty of Science, University of Porto, Rua do Campo Alegre 687, 4169-007 Porto (Portugal).

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http://doi.wiley.com/10.1002/cmdc.201402205
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http://dx.doi.org/10.1002/cmdc.201402205DOI Listing
October 2014

Similarity-based modeling in large-scale prediction of drug-drug interactions.

Nat Protoc 2014 Sep 14;9(9):2147-63. Epub 2014 Aug 14.

1] Department of Biomedical Informatics, Columbia University Medical Center, New York, New York, USA. [2] Department of Systems Biology, Columbia University Medical Center, New York, New York, USA. [3] Department of Medicine, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nprot.2014.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422192PMC
September 2014

Monoamine oxidase (MAO) inhibitory activity: 3-phenylcoumarins versus 4-hydroxy-3-phenylcoumarins.

ChemMedChem 2014 Aug 29;9(8):1672-6. Epub 2014 Apr 29.

Department of Life Sciences & Environment, Section of Pharmaceutical Sciences, University of Cagliari, Palazzo delle Scienze, Via Ospedale, 72, 09124 Cagliari (Italy).

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http://dx.doi.org/10.1002/cmdc.201402010DOI Listing
August 2014

Insight into the functional and structural properties of 3-arylcoumarin as an interesting scaffold in monoamine oxidase B inhibition.

ChemMedChem 2014 Jul 8;9(7):1488-500. Epub 2014 Apr 8.

Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela (Spain).

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http://dx.doi.org/10.1002/cmdc.201300533DOI Listing
July 2014

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.

Elife 2014 May 20;3:e02523. Epub 2014 May 20.

Department of Biological Sciences, Columbia University, New York, United States Department of Systems Biology, Columbia University, New York, United States Department of Chemistry, Columbia University, New York, United States Howard Hughes Medical Institute, Columbia University, New York, United States

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http://dx.doi.org/10.7554/eLife.02523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054777PMC
May 2014

Disease risk factors identified through shared genetic architecture and electronic medical records.

Sci Transl Med 2014 Apr;6(234):234ra57

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, 1265 Welch Road, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1126/scitranslmed.3007191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323098PMC
April 2014

Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association.

PLoS Genet 2014 Feb 6;10(2):e1004122. Epub 2014 Feb 6.

Department of Biomedical Informatics, Department of Systems Biology, and Department of Medicine, Columbia University, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916285PMC
February 2014

Improving the prediction of pharmacogenes using text-derived drug-gene relationships.

Pac Symp Biocomput 2010 :305-14

Stanford Biomedical Informatics Training Program, Stanford University, Stanford, CA 94305, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092476PMC
http://dx.doi.org/10.1142/9789814295291_0033DOI Listing
November 2013

High-throughput methods for combinatorial drug discovery.

Sci Transl Med 2013 Oct;5(205):205rv1

Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1126/scitranslmed.3006667DOI Listing
October 2013

Detection of drug-drug interactions by modeling interaction profile fingerprints.

PLoS One 2013 8;8(3):e58321. Epub 2013 Mar 8.

Department of Biomedical Informatics, Columbia University Medical Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058321PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592896PMC
September 2013

Web-scale pharmacovigilance: listening to signals from the crowd.

J Am Med Inform Assoc 2013 May 6;20(3):404-8. Epub 2013 Mar 6.

Microsoft Research, Redmond, Washington 98052, USA.

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http://dx.doi.org/10.1136/amiajnl-2012-001482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628066PMC
May 2013

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study.

Eur J Med Chem 2013 May 16;63:151-61. Epub 2013 Feb 16.

Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.

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http://dx.doi.org/10.1016/j.ejmech.2013.02.009DOI Listing
May 2013

A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports.

J Am Med Inform Assoc 2012 Jan-Feb;19(1):79-85. Epub 2011 Jun 14.

Biomedical Informatics Training Program, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1136/amiajnl-2011-000214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240755PMC
March 2012

Data-driven prediction of drug effects and interactions.

Sci Transl Med 2012 Mar;4(125):125ra31

Biomedical Informatics Training Program, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1126/scitranslmed.3003377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382018PMC
March 2012

Cooperative transcription factor associations discovered using regulatory variation.

Proc Natl Acad Sci U S A 2011 Aug 26;108(32):13353-8. Epub 2011 Jul 26.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1103105108
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http://dx.doi.org/10.1073/pnas.1103105108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156166PMC
August 2011

An integrative method for scoring candidate genes from association studies: application to warfarin dosing.

BMC Bioinformatics 2010 Oct 28;11 Suppl 9:S9. Epub 2010 Oct 28.

Biomedical Informatics Training Program, Stanford University School of Medicine, Stanford, CA, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-11-S9-S9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967750PMC
October 2010

Predicting drug side-effects by chemical systems biology.

Genome Biol 2009 2;10(9):238. Epub 2009 Sep 2.

Training Program in Biomedical Informatics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1186/gb-2009-10-9-238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768971PMC
February 2010