Publications by authors named "Nicholas P Restifo"

100Publications

Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.

Cancer Cell 2020 06;37(6):818-833.e9

Surgery Branch, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD 20892, USA; Center for Cell-based Therapy, Center for Cancer Research, National Institutes of Health (NIH), Bethesda, MD 20892, USA; Immunology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2020.05.004DOI Listing
June 2020

Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.

Sci Rep 2020 03 30;10(1):5688. Epub 2020 Mar 30.

Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Rockville, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-62369-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105471PMC
March 2020

Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.

J Immunother Cancer 2020 01;8(1)

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jitc-2019-000210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057422PMC
January 2020

Identifying the source of tumour-infiltrating T cells.

Nature 2019 12;576(7787):385-386

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/d41586-019-03670-6DOI Listing
December 2019

Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells.

J Vis Exp 2019 10 24(152). Epub 2019 Oct 24.

Surgery Branch, National Cancer Institute, NIH; Center for Cell-Based Therapy, National Cancer Institute, NIH.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/59997DOI Listing
October 2019

Developing neoantigen-targeted T cell-based treatments for solid tumors.

Nat Med 2019 10 7;25(10):1488-1499. Epub 2019 Oct 7.

Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41591-019-0596-yDOI Listing
October 2019

Defining 'T cell exhaustion'.

Nat Rev Immunol 2019 11 30;19(11):665-674. Epub 2019 Sep 30.

Division of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41577-019-0221-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286441PMC
November 2019

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants.

J Vis Exp 2019 08 9(150). Epub 2019 Aug 9.

Surgery Branch, National Cancer Institute, NIH; Center for Cell-Based Therapy, National Cancer Institute, NIH.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/58672DOI Listing
August 2019

The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction.

Cell 2019 08;178(5):1088-1101.e15

Metaorganism Immunity Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2019.07.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818271PMC
August 2019

Mg regulation of kinase signaling and immune function.

J Exp Med 2019 08 13;216(8):1828-1842. Epub 2019 Jun 13.

Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20181970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683994PMC
August 2019

An effective mouse model for adoptive cancer immunotherapy targeting neoantigens.

JCI Insight 2019 05 16;4(10). Epub 2019 May 16.

Surgery Branch, National Cancer Institute (NCI), NIH, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/jci.insight.124405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542630PMC
May 2019

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.

Cell 2018 12 1;175(7):1780-1795.e19. Epub 2018 Nov 1.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Center for Immunobiology, Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674183130
Publisher Site
http://dx.doi.org/10.1016/j.cell.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361668PMC
December 2018

The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8 T cells.

Sci Rep 2018 03 28;8(1):5336. Epub 2018 Mar 28.

Laboratory of Cellular and Molecular Biology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Maryland, 20892-4256, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-23549-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871872PMC
March 2018

Epigenetic control of CD8 T cell differentiation.

Nat Rev Immunol 2018 05 30;18(5):340-356. Epub 2018 Jan 30.

Center for Cell-Based Therapy, National Cancer Institute (NCI).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nri.2017.146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327307PMC
May 2018

Silencing stemness in T cell differentiation.

Science 2018 01;359(6372):163-164

Center for Cell-Based Therapy, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aar5541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312704PMC
January 2018

Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy.

Cell Metab 2017 Jul;26(1):94-109

Center for Cell-Based Therapy, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA; Surgery Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2017.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543711PMC
July 2017

Novel "Elements" of Immune Suppression within the Tumor Microenvironment.

Cancer Immunol Res 2017 06;5(6):426-433

Surgery Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-17-0117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512605PMC
June 2017

Metabolic reprograming of anti-tumor immunity.

Curr Opin Immunol 2017 Jun 13;46:14-22. Epub 2017 Apr 13.

Center for Cell-Based Therapy, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA; Surgery Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coi.2017.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327315PMC
June 2017

Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction.

Nat Commun 2016 12 23;7:13895. Epub 2016 Dec 23.

Immunoregulation Section, Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Intramural Research Program, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms13895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196435PMC
December 2016

Arginine Arms T Cells to Thrive and Survive.

Cell Metab 2016 11;24(5):647-648

Center for Cell-Based Therapy, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA; Surgery Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2016.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327309PMC
November 2016

Preclinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers.

Clin Cancer Res 2017 May 1;23(9):2267-2276. Epub 2016 Nov 1.

Surgery Branch and Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-16-1421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411349PMC
May 2017

Targeting Akt in cell transfer immunotherapy for cancer.

Oncoimmunology 2016 29;5(9):e1014776. Epub 2015 Dec 29.

Surgery Branch of National Cancer Institute; National Institutes of Health ; Bethesda, MD USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/2162402X.2015.1014776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048755PMC
December 2015

Customizing Functionality and Payload Delivery for Receptor-Engineered T Cells.

Cell 2016 Oct;167(2):304-306

Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Center for Cell-Based Therapy, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2016.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312703PMC
October 2016

Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.

Cell 2016 Aug;166(5):1117-1131.e14

Surgery Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA; Center for Cell-based Therapy, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2016.07.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548538PMC
August 2016

Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets.

J Immunol 2016 07 6;197(2):644-54. Epub 2016 Jun 6.

Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016; Department of Pathology, New York University School of Medicine, New York, NY 10016

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1600178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935560PMC
July 2016

Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.

J Clin Oncol 2016 07 23;34(20):2389-97. Epub 2016 May 23.

Stephanie L. Goff, Deborah E. Citrin, Robert P. Somerville, John R. Wunderlich, David N. Danforth, James C. Yang, Richard M. Sherry, Udai S. Kammula, Christopher A. Klebanoff, Marybeth S. Hughes, Nicholas P. Restifo, Michelle M. Langhan, Thomas E. Shelton, Lily Lu, Mei Li M. Kwong, Sadia Ilyas, Nicholas D. Klemen, Eden C. Payabyab, Kathleen E. Morton, Mary Ann Toomey, Seth M. Steinberg, Donald E. White, and Steven A. Rosenberg, National Cancer Institute, National Institutes of Health; Daniel A. Zlott, Clinical Center, National Institutes of Health, Bethesda, MD; and Mark E. Dudley, Novartis Institutes for BioMedical Research, Cambridge, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.66.7220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981979PMC
July 2016

Acquired resistance to immunotherapy and future challenges.

Nat Rev Cancer 2016 02;16(2):121-6

Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, New York 10065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrc.2016.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330026PMC
February 2016

Prospects for gene-engineered T cell immunotherapy for solid cancers.

Nat Med 2016 Jan;22(1):26-36

Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.4015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295670PMC
January 2016

Identification of T-cell Receptors Targeting KRAS-Mutated Human Tumors.

Cancer Immunol Res 2016 Mar 23;4(3):204-14. Epub 2015 Dec 23.

Surgery Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-15-0188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775432PMC
March 2016

Nutrient Competition: A New Axis of Tumor Immunosuppression.

Cell 2015 Sep;162(6):1206-8

Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2015.08.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327313PMC
September 2015

Adoptive cell transfer as personalized immunotherapy for human cancer.

Science 2015 Apr;348(6230):62-8

Surgery Branch, National Cancer Institute, Center for Cancer Research, National Institutes of Health, 9000 Rockville Pike, CRC Building, Room 3W-3940, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aaa4967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295668PMC
April 2015

The interplay of effector and regulatory T cells in cancer.

Curr Opin Immunol 2015 Apr 27;33:101-11. Epub 2015 Feb 27.

National Cancer Institute (NCI), National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coi.2015.02.003DOI Listing
April 2015

Super-enhancers delineate disease-associated regulatory nodes in T cells.

Nature 2015 Apr 16;520(7548):558-62. Epub 2015 Feb 16.

Lymphocyte Cell Biology Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409450PMC
April 2015

Microbiota modulation of myeloid cells in cancer therapy.

Cancer Immunol Res 2015 Feb;3(2):103-9

Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-14-0225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324508PMC
February 2015

Mouse model for pre-clinical study of human cancer immunotherapy.

Curr Protoc Immunol 2015 Feb 2;108:20.1.1-20.1.43. Epub 2015 Feb 2.

National Cancer Institute, Surgery Branch, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/0471142735.im2001s108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361407PMC
February 2015

Classification of current anticancer immunotherapies.

Oncotarget 2014 Dec;5(24):12472-508

Equipe 11 labellisée pas la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France. INSERM, U1138, Paris, France. Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France. Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France. Pôle de Biologie, Hôpital Européen Georges Pompidou (HEGP), AP-HP, Paris, France.

View Article

Download full-text PDF

Source
https://lirias.kuleuven.be/bitstream/123456789/502976/1/2998
Web Search
http://oncotarget.com/abstract/2998
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350348PMC
http://dx.doi.org/10.18632/oncotarget.2998DOI Listing
December 2014

Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation.

Vaccine 2015 Feb 1;33(7):914-23. Epub 2014 Nov 1.

Department of Dermatology, University Hospital CHUV, 1011 Lausanne, Switzerland; Institute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2014.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439469PMC
February 2015

Immunotherapy: Treatment of aggressive lymphomas with anti-CD19 CAR T cells.

Nat Rev Clin Oncol 2014 Dec 11;11(12):685-6. Epub 2014 Nov 11.

Center for Cancer Research, Surgery Branch, Immunotherapy Section, 10 Center Drive, Building 10/CRC, Room 3 West-5816, Bethesda, MA 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2014.190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327311PMC
December 2014

Big bang theory of stem-like T cells confirmed.

Blood 2014 Jul;124(4):476-7

NATIONAL CANCER INSTITUTE.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2014-06-578989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110654PMC
July 2014

Identification of the genomic insertion site of Pmel-1 TCR α and β transgenes by next-generation sequencing.

PLoS One 2014 14;9(5):e96650. Epub 2014 May 14.

Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096650PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020793PMC
December 2014

Reprogramming antitumor immunity.

Trends Immunol 2014 Apr 21;35(4):178-85. Epub 2014 Mar 21.

National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Center for Regenerative Medicine, National Institutes of Health, NIH, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.it.2014.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373650PMC
April 2014

Human memory T cells: generation, compartmentalization and homeostasis.

Nat Rev Immunol 2014 Jan 13;14(1):24-35. Epub 2013 Dec 13.

National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nri3567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032067PMC
January 2014

Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy.

Immunol Rev 2014 Jan;257(1):264-276

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imr.12135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915736PMC
January 2014

Lineage relationship of effector and memory T cells.

Curr Opin Immunol 2013 Oct 20;25(5):556-63. Epub 2013 Oct 20.

Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coi.2013.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858177PMC
October 2013

Reassessing target antigens for adoptive T-cell therapy.

Nat Biotechnol 2013 Nov 20;31(11):999-1008. Epub 2013 Oct 20.

National Cancer Institute, Surgery Branch, National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.2725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280065PMC
November 2013

A "big data" view of the tumor "immunome".

Immunity 2013 Oct;39(4):631-2

Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Center for Regenerative Medicine, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901363PMC
http://dx.doi.org/10.1016/j.immuni.2013.10.002DOI Listing
October 2013

Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells.

Eur J Immunol 2014 Jan 21;44(1):69-79. Epub 2013 Nov 21.

Laboratory of Molecular and Tumor Immunology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, OR, USA; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201343718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283993PMC
January 2014

Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia.

J Exp Med 2013 Jun 27;210(6):1125-35. Epub 2013 May 27.

Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20130110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674706PMC
June 2013

Collapse of the tumor stroma is triggered by IL-12 induction of Fas.

Mol Ther 2013 Jul 9;21(7):1369-77. Epub 2013 Apr 9.

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mt.2013.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702103PMC
July 2013

Moving T memory stem cells to the clinic.

Blood 2013 Jan;121(4):567-8

National Institutes of Health, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2012-11-468660DOI Listing
January 2013

Essentials of Th17 cell commitment and plasticity.

Blood 2013 Mar 16;121(13):2402-14. Epub 2013 Jan 16.

Hematology Branch, National Heart, Lung and Blood Institute, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2012-09-378653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612853PMC
March 2013

Double or nothing on cancer immunotherapy.

Nat Biotechnol 2013 Jan;31(1):33-4

Center for Cancer Research, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.2471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352981PMC
January 2013

Memoirs of a reincarnated T cell.

Cell Stem Cell 2013 Jan;12(1):6-8

National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2012.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352969PMC
January 2013

Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors.

J Immunother Cancer 2013 29;1:11. Epub 2013 Jul 29.

Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA ; NIH Center for Regenerative Medicine, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/2051-1426-1-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019909PMC
June 2014

Identification, isolation and in vitro expansion of human and nonhuman primate T stem cell memory cells.

Nat Protoc 2013 Jan 6;8(1):33-42. Epub 2012 Dec 6.

ImmunoTechnology Section, Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases, US National Institutes of Health (NIH), Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2012.143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328292PMC
January 2013