Nicholas J White

Nicholas J White

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Nicholas J White

Nicholas J White

Publications by authors named "Nicholas J White"

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Why is WHO failing women with falciparum malaria in the first trimester of pregnancy?

Lancet 2020 03;395(10226):779

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)30161-6DOI Listing
March 2020

Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.

Lancet 2020 Mar 11. Epub 2020 Mar 11.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)30552-3DOI Listing
March 2020

Polymorphic markers for identification of parasite population in Plasmodium malariae.

Malar J 2020 Jan 28;19(1):48. Epub 2020 Jan 28.

Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1186/s12936-020-3122-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988369PMC
January 2020

Resolving the cause of recurrent Plasmodium vivax malaria probabilistically.

Nat Commun 2019 12 6;10(1):5595. Epub 2019 Dec 6.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1038/s41467-019-13412-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898227PMC
December 2019

A sensor array for the discrimination of polycyclic aromatic hydrocarbons using conjugated polymers and the inner filter effect.

Chem Sci 2019 Nov 7;10(44):10247-10255. Epub 2019 Oct 7.

Department of Chemistry and Biochemistry , The University of Alabama , P.O. Box 870336 , Tuscaloosa , AL 35487 , USA . Email:

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http://dx.doi.org/10.1039/c9sc03405fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020785PMC
November 2019

Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance.

Authors:
Nicholas J White

Malar J 2019 Oct 11;18(1):338. Epub 2019 Oct 11.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1186/s12936-019-2955-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777025PMC
October 2019

A Temporizing Solution to "Artemisinin Resistance".

N Engl J Med 2019 09;381(10):989-990

Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.

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http://dx.doi.org/10.1056/NEJMc1909337DOI Listing
September 2019

Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies.

PLoS Med 2019 08 23;16(8):e1002858. Epub 2019 Aug 23.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1371/journal.pmed.1002858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707545PMC
August 2019

Optimal Duration of Follow-up for Assessing Antimalarial Efficacy in Pregnancy: A Retrospective Analysis of a Cohort Followed Up Until Delivery on the Thailand-Myanmar Border.

Open Forum Infect Dis 2019 Jul 31;6(7):ofz264. Epub 2019 May 31.

Shoklo Malaria Research Unit (SMRU), Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Tak, Thailand.

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http://dx.doi.org/10.1093/ofid/ofz264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602886PMC
July 2019

Plasmodium vivax Relapse Rates Following Plasmodium falciparum Malaria Reflect Previous Transmission Intensity.

J Infect Dis 2019 06;220(1):100-104

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1093/infdis/jiz052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548896PMC
June 2019

Pharmacokinetic-Pharmacodynamic Assessment of the Hepatic and Bone Marrow Toxicities of the New Trypanoside Fexinidazole.

Antimicrob Agents Chemother 2019 04 27;63(4). Epub 2019 Mar 27.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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http://dx.doi.org/10.1128/AAC.02515-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496162PMC
April 2019

The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.

PLoS Med 2019 02 15;16(2):e1002745. Epub 2019 Feb 15.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1371/journal.pmed.1002745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377128PMC
February 2019

Tafenoquine - A Radical Improvement?

Authors:
Nicholas J White

N Engl J Med 2019 01;380(3):285-286

From Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, and the Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1056/NEJMe1816383DOI Listing
January 2019

Collider bias and the apparent protective effect of glucose-6-phosphate dehydrogenase deficiency on cerebral malaria.

Elife 2019 01 28;8. Epub 2019 Jan 28.

Nuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.7554/eLife.43154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361583PMC
January 2019

Pharmacokinetics of oral tenofovir disoproxil fumarate in pregnancy and lactation: a systematic review.

Antivir Ther 2019 ;24(7):529-540

Department of Internal Medicine and Tropical Diseases, Amsterdam University Medical Center, location Academic Medical Center Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.3851/IMP3341DOI Listing
January 2019

The arrhythmogenic cardiotoxicity of the quinoline and structurally related antimalarial drugs: a systematic review.

BMC Med 2018 11 7;16(1):200. Epub 2018 Nov 7.

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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https://bmcmedicine.biomedcentral.com/articles/10.1186/s1291
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http://dx.doi.org/10.1186/s12916-018-1188-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220451PMC
November 2018

Real time PCR detection of common CYP2D6 genetic variants and its application in a Karen population study.

Malar J 2018 Nov 15;17(1):427. Epub 2018 Nov 15.

Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1186/s12936-018-2579-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238304PMC
November 2018

Anaemia and malaria.

Authors:
Nicholas J White

Malar J 2018 Oct 19;17(1):371. Epub 2018 Oct 19.

Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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https://malariajournal.biomedcentral.com/articles/10.1186/s1
Publisher Site
http://dx.doi.org/10.1186/s12936-018-2509-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194647PMC
October 2018

The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis.

Lancet Infect Dis 2018 09 20;18(9):1025-1034. Epub 2018 Jul 20.

Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, NT, Australia; WorldWide Antimalarial Resistance Network, Clinical module, Darwin, NT, Australia; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(18)30348-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105624PMC
September 2018

Risk of sudden unexplained death after use of dihydroartemisinin-piperaquine for malaria: a systematic review and Bayesian meta-analysis.

Lancet Infect Dis 2018 08 18;18(8):913-923. Epub 2018 Jun 18.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

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http://dx.doi.org/10.1016/S1473-3099(18)30297-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060085PMC
August 2018

Characterizing Blood-Stage Antimalarial Drug MIC Values Using Reinfection Patterns.

Antimicrob Agents Chemother 2018 07 26;62(7). Epub 2018 Jun 26.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.

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http://dx.doi.org/10.1128/AAC.02476-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021672PMC
July 2018

Infectivity of Chronic Malaria Infections and Its Consequences for Control and Elimination.

Clin Infect Dis 2018 07;67(2):295-302

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1093/cid/ciy055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030896PMC
July 2018

Genetic polymorphisms in the circumsporozoite protein of Plasmodium malariae show a geographical bias.

Malar J 2018 Jul 16;17(1):269. Epub 2018 Jul 16.

Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1186/s12936-018-2413-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048912PMC
July 2018

Drugs that reduce transmission of falciparum malaria.

Lancet Infect Dis 2018 06 6;18(6):585-586. Epub 2018 Feb 6.

Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1016/S1473-3099(18)30070-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985155PMC
June 2018

The persistence and oscillations of submicroscopic Plasmodium falciparum and Plasmodium vivax infections over time in Vietnam: an open cohort study.

Lancet Infect Dis 2018 05 2;18(5):565-572. Epub 2018 Feb 2.

Oxford University Clinical Research Unit, Wellcome Trust Major Oversea Programme, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Churchill Hospital, Oxford, UK.

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http://dx.doi.org/10.1016/S1473-3099(18)30046-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910058PMC
May 2018

Use of primaquine and glucose-6-phosphate dehydrogenase deficiency testing: Divergent policies and practices in malaria endemic countries.

PLoS Negl Trop Dis 2018 04 19;12(4):e0006230. Epub 2018 Apr 19.

Mahidol-Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1371/journal.pntd.0006230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908060PMC
April 2018

Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria.

PLoS Negl Trop Dis 2018 04 20;12(4):e0006440. Epub 2018 Apr 20.

Mahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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https://dx.plos.org/10.1371/journal.pntd.0006440
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0006440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931686PMC
April 2018

Primaquine-induced haemolysis in females heterozygous for G6PD deficiency.

Malar J 2018 Mar 2;17(1):101. Epub 2018 Mar 2.

Department of Haematology, Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania.

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http://dx.doi.org/10.1186/s12936-018-2248-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833093PMC
March 2018

Acidosis and acute kidney injury in severe malaria.

Malar J 2018 Mar 23;17(1):128. Epub 2018 Mar 23.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1186/s12936-018-2274-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865348PMC
March 2018

Chloroquine-Primaquine versus Chloroquine Alone to Treat Vivax Malaria in Afghanistan: An Open Randomized Superiority Trial.

Am J Trop Med Hyg 2017 Dec 26;97(6):1782-1787. Epub 2017 Oct 26.

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.4269/ajtmh.17-0290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805052PMC
December 2017

Quantification of the antimalarial drug pyronaridine in whole blood using LC-MS/MS - Increased sensitivity resulting from reduced non-specific binding.

J Pharm Biomed Anal 2017 Nov 26;146:214-219. Epub 2017 Aug 26.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/j.jpba.2017.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637160PMC
November 2017

Population Pharmacokinetic and Pharmacodynamic Modeling of Artemisinin Resistance in Southeast Asia.

AAPS J 2017 11 11;19(6):1842-1854. Epub 2017 Sep 11.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok, 10400, Thailand.

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http://dx.doi.org/10.1208/s12248-017-0141-1DOI Listing
November 2017

Identifying Malaria Hot Spots.

Authors:
Nicholas J White

J Infect Dis 2017 11;216(9):1051-1052

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1093/infdis/jix330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853899PMC
November 2017

Spread of a single multidrug resistant malaria parasite lineage (PfPailin) to Vietnam.

Lancet Infect Dis 2017 10;17(10):1022-1023

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(17)30524-8DOI Listing
October 2017