Nicholas J Schork

Nicholas J Schork

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Nicholas J Schork

Publications by authors named "Nicholas J Schork"

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Strategies for testing intervention matching schemes in cancer.

Clin Pharmacol Ther 2020 Jun 14. Epub 2020 Jun 14.

The Translational Genomics Research Institute (TGen), Phoenix, AZ, United States.

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http://dx.doi.org/10.1002/cpt.1947DOI Listing
June 2020

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.

Authors:
Melissa A Munn-Chernoff Emma C Johnson Yi-Ling Chou Jonathan R I Coleman Laura M Thornton Raymond K Walters Zeynep Yilmaz Jessica H Baker Christopher Hübel Scott Gordon Sarah E Medland Hunna J Watson Héléna A Gaspar Julien Bryois Anke Hinney Virpi M Leppä Manuel Mattheisen Stephan Ripke Shuyang Yao Paola Giusti-Rodríguez Ken B Hanscombe Roger A H Adan Lars Alfredsson Tetsuya Ando Ole A Andreassen Wade H Berrettini Ilka Boehm Claudette Boni Vesna Boraska Perica Katharina Buehren Roland Burghardt Matteo Cassina Sven Cichon Maurizio Clementi Roger D Cone Philippe Courtet Scott Crow James J Crowley Unna N Danner Oliver S P Davis Martina de Zwaan George Dedoussis Daniela Degortes Janiece E DeSocio Danielle M Dick Dimitris Dikeos Christian Dina Monika Dmitrzak-Weglarz Elisa Docampo Laramie E Duncan Karin Egberts Stefan Ehrlich Geòrgia Escaramís Tõnu Esko Xavier Estivill Anne Farmer Angela Favaro Fernando Fernández-Aranda Manfred M Fichter Krista Fischer Manuel Föcker Lenka Foretova Andreas J Forstner Monica Forzan Christopher S Franklin Steven Gallinger Ina Giegling Johanna Giuranna Fragiskos Gonidakis Philip Gorwood Monica Gratacos Mayora Sébastien Guillaume Yiran Guo Hakon Hakonarson Konstantinos Hatzikotoulas Joanna Hauser Johannes Hebebrand Sietske G Helder Stefan Herms Beate Herpertz-Dahlmann Wolfgang Herzog Laura M Huckins James I Hudson Hartmut Imgart Hidetoshi Inoko Vladimir Janout Susana Jiménez-Murcia Antonio Julià Gursharan Kalsi Deborah Kaminská Leila Karhunen Andreas Karwautz Martien J H Kas James L Kennedy Anna Keski-Rahkonen Kirsty Kiezebrink Youl-Ri Kim Kelly L Klump Gun Peggy S Knudsen Maria C La Via Stephanie Le Hellard Robert D Levitan Dong Li Lisa Lilenfeld Bochao Danae Lin Jolanta Lissowska Jurjen Luykx Pierre J Magistretti Mario Maj Katrin Mannik Sara Marsal Christian R Marshall Morten Mattingsdal Sara McDevitt Peter McGuffin Andres Metspalu Ingrid Meulenbelt Nadia Micali Karen Mitchell Alessio Maria Monteleone Palmiero Monteleone Benedetta Nacmias Marie Navratilova Ioanna Ntalla Julie K O'Toole Roel A Ophoff Leonid Padyukov Aarno Palotie Jacques Pantel Hana Papezova Dalila Pinto Raquel Rabionet Anu Raevuori Nicolas Ramoz Ted Reichborn-Kjennerud Valdo Ricca Samuli Ripatti Franziska Ritschel Marion Roberts Alessandro Rotondo Dan Rujescu Filip Rybakowski Paolo Santonastaso André Scherag Stephen W Scherer Ulrike Schmidt Nicholas J Schork Alexandra Schosser Jochen Seitz Lenka Slachtova P Eline Slagboom Margarita C T Slof-Op't Landt Agnieszka Slopien Sandro Sorbi Beata Świątkowska Jin P Szatkiewicz Ioanna Tachmazidou Elena Tenconi Alfonso Tortorella Federica Tozzi Janet Treasure Artemis Tsitsika Marta Tyszkiewicz-Nwafor Konstantinos Tziouvas Annemarie A van Elburg Eric F van Furth Gudrun Wagner Esther Walton Elisabeth Widen Eleftheria Zeggini Stephanie Zerwas Stephan Zipfel Andrew W Bergen Joseph M Boden Harry Brandt Steven Crawford Katherine A Halmi L John Horwood Craig Johnson Allan S Kaplan Walter H Kaye James Mitchell Catherine M Olsen John F Pearson Nancy L Pedersen Michael Strober Thomas Werge David C Whiteman D Blake Woodside Jakob Grove Anjali K Henders Janne T Larsen Richard Parker Liselotte V Petersen Jennifer Jordan Martin A Kennedy Andreas Birgegård Paul Lichtenstein Claes Norring Mikael Landén Preben Bo Mortensen Renato Polimanti Jeanette N McClintick Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Franziska Degenhardt Anna R Docherty Alexis C Edwards Jerome C Foo Louis Fox Josef Frank Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Colin Hodgkinson Per Hoffmann Jouke-Jan Hottenga Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen Roseann E Peterson Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Hang Zhou Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Mark A Frye Wolfgang Gäebel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer Gabriele Koller John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie H Witt Norbert Wodarz Peter Zill Daniel E Adkins Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz E Jane Costello Harriet de Wit Nancy Diazgranados Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Victor Hesselbrock John K Hewitt Christian J Hopfer William G Iacono Eric O Johnson Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik K E Magnusson Elliot C Nelson Markus M Nöthen Abraham A Palmer Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard J Rose Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Tracey D Wade Andrew C Heath Grant W Montgomery Nicholas G Martin Patrick F Sullivan Jaakko Kaprio Gerome Breen Joel Gelernter Howard J Edenberg Cynthia M Bulik Arpana Agrawal

Addict Biol 2020 Feb 16:e12880. Epub 2020 Feb 16.

Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA.

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http://dx.doi.org/10.1111/adb.12880DOI Listing
February 2020

Genetic Support for Longevity-Enhancing Drug Targets: Issues, Preliminary Data, and Future Directions.

J Gerontol A Biol Sci Med Sci 2019 11;74(Suppl_1):S61-S71

Department of Quantitative Medicine and Systems Biology, The Translational Genomics Research Institute (TGen), Phoenix, Arizona.

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http://dx.doi.org/10.1093/gerona/glz206DOI Listing
November 2019

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

Authors:
Hunna J Watson Zeynep Yilmaz Laura M Thornton Christopher Hübel Jonathan R I Coleman Héléna A Gaspar Julien Bryois Anke Hinney Virpi M Leppä Manuel Mattheisen Sarah E Medland Stephan Ripke Shuyang Yao Paola Giusti-Rodríguez Ken B Hanscombe Kirstin L Purves Roger A H Adan Lars Alfredsson Tetsuya Ando Ole A Andreassen Jessica H Baker Wade H Berrettini Ilka Boehm Claudette Boni Vesna Boraska Perica Katharina Buehren Roland Burghardt Matteo Cassina Sven Cichon Maurizio Clementi Roger D Cone Philippe Courtet Scott Crow James J Crowley Unna N Danner Oliver S P Davis Martina de Zwaan George Dedoussis Daniela Degortes Janiece E DeSocio Danielle M Dick Dimitris Dikeos Christian Dina Monika Dmitrzak-Weglarz Elisa Docampo Laramie E Duncan Karin Egberts Stefan Ehrlich Geòrgia Escaramís Tõnu Esko Xavier Estivill Anne Farmer Angela Favaro Fernando Fernández-Aranda Manfred M Fichter Krista Fischer Manuel Föcker Lenka Foretova Andreas J Forstner Monica Forzan Christopher S Franklin Steven Gallinger Ina Giegling Johanna Giuranna Fragiskos Gonidakis Philip Gorwood Monica Gratacos Mayora Sébastien Guillaume Yiran Guo Hakon Hakonarson Konstantinos Hatzikotoulas Joanna Hauser Johannes Hebebrand Sietske G Helder Stefan Herms Beate Herpertz-Dahlmann Wolfgang Herzog Laura M Huckins James I Hudson Hartmut Imgart Hidetoshi Inoko Vladimir Janout Susana Jiménez-Murcia Antonio Julià Gursharan Kalsi Deborah Kaminská Jaakko Kaprio Leila Karhunen Andreas Karwautz Martien J H Kas James L Kennedy Anna Keski-Rahkonen Kirsty Kiezebrink Youl-Ri Kim Lars Klareskog Kelly L Klump Gun Peggy S Knudsen Maria C La Via Stephanie Le Hellard Robert D Levitan Dong Li Lisa Lilenfeld Bochao Danae Lin Jolanta Lissowska Jurjen Luykx Pierre J Magistretti Mario Maj Katrin Mannik Sara Marsal Christian R Marshall Morten Mattingsdal Sara McDevitt Peter McGuffin Andres Metspalu Ingrid Meulenbelt Nadia Micali Karen Mitchell Alessio Maria Monteleone Palmiero Monteleone Melissa A Munn-Chernoff Benedetta Nacmias Marie Navratilova Ioanna Ntalla Julie K O'Toole Roel A Ophoff Leonid Padyukov Aarno Palotie Jacques Pantel Hana Papezova Dalila Pinto Raquel Rabionet Anu Raevuori Nicolas Ramoz Ted Reichborn-Kjennerud Valdo Ricca Samuli Ripatti Franziska Ritschel Marion Roberts Alessandro Rotondo Dan Rujescu Filip Rybakowski Paolo Santonastaso André Scherag Stephen W Scherer Ulrike Schmidt Nicholas J Schork Alexandra Schosser Jochen Seitz Lenka Slachtova P Eline Slagboom Margarita C T Slof-Op 't Landt Agnieszka Slopien Sandro Sorbi Beata Świątkowska Jin P Szatkiewicz Ioanna Tachmazidou Elena Tenconi Alfonso Tortorella Federica Tozzi Janet Treasure Artemis Tsitsika Marta Tyszkiewicz-Nwafor Konstantinos Tziouvas Annemarie A van Elburg Eric F van Furth Gudrun Wagner Esther Walton Elisabeth Widen Eleftheria Zeggini Stephanie Zerwas Stephan Zipfel Andrew W Bergen Joseph M Boden Harry Brandt Steven Crawford Katherine A Halmi L John Horwood Craig Johnson Allan S Kaplan Walter H Kaye James E Mitchell Catherine M Olsen John F Pearson Nancy L Pedersen Michael Strober Thomas Werge David C Whiteman D Blake Woodside Garret D Stuber Scott Gordon Jakob Grove Anjali K Henders Anders Juréus Katherine M Kirk Janne T Larsen Richard Parker Liselotte Petersen Jennifer Jordan Martin Kennedy Grant W Montgomery Tracey D Wade Andreas Birgegård Paul Lichtenstein Claes Norring Mikael Landén Nicholas G Martin Preben Bo Mortensen Patrick F Sullivan Gerome Breen Cynthia M Bulik

Nat Genet 2019 08 15;51(8):1207-1214. Epub 2019 Jul 15.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1038/s41588-019-0439-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779477PMC
August 2019

Power and Design Issues in Crossover-Based N-Of-1 Clinical Trials with Fixed Data Collection Periods.

Healthcare (Basel) 2019 Jul 2;7(3). Epub 2019 Jul 2.

Quantitative Medicine and Systems Biology, The Translational Genomics Research Institute (TGen), an affiliate of the City of Hope National Medical Center, 445 North Fifth Street, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.3390/healthcare7030084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787650PMC
July 2019

Artificial Intelligence and Personalized Medicine.

Cancer Treat Res 2019 ;178:265-283

Department of Quantitative Medicine, The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.

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http://dx.doi.org/10.1007/978-3-030-16391-4_11DOI Listing
June 2019

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Authors:
Eli A Stahl Gerome Breen Andreas J Forstner Andrew McQuillin Stephan Ripke Vassily Trubetskoy Manuel Mattheisen Yunpeng Wang Jonathan R I Coleman Héléna A Gaspar Christiaan A de Leeuw Stacy Steinberg Jennifer M Whitehead Pavlides Maciej Trzaskowski Enda M Byrne Tune H Pers Peter A Holmans Alexander L Richards Liam Abbott Esben Agerbo Huda Akil Diego Albani Ney Alliey-Rodriguez Thomas D Als Adebayo Anjorin Verneri Antilla Swapnil Awasthi Judith A Badner Marie Bækvad-Hansen Jack D Barchas Nicholas Bass Michael Bauer Richard Belliveau Sarah E Bergen Carsten Bøcker Pedersen Erlend Bøen Marco P Boks James Boocock Monika Budde William Bunney Margit Burmeister Jonas Bybjerg-Grauholm William Byerley Miquel Casas Felecia Cerrato Pablo Cervantes Kimberly Chambert Alexander W Charney Danfeng Chen Claire Churchhouse Toni-Kim Clarke William Coryell David W Craig Cristiana Cruceanu David Curtis Piotr M Czerski Anders M Dale Simone de Jong Franziska Degenhardt Jurgen Del-Favero J Raymond DePaulo Srdjan Djurovic Amanda L Dobbyn Ashley Dumont Torbjørn Elvsåshagen Valentina Escott-Price Chun Chieh Fan Sascha B Fischer Matthew Flickinger Tatiana M Foroud Liz Forty Josef Frank Christine Fraser Nelson B Freimer Louise Frisén Katrin Gade Diane Gage Julie Garnham Claudia Giambartolomei Marianne Giørtz Pedersen Jaqueline Goldstein Scott D Gordon Katherine Gordon-Smith Elaine K Green Melissa J Green Tiffany A Greenwood Jakob Grove Weihua Guan José Guzman-Parra Marian L Hamshere Martin Hautzinger Urs Heilbronner Stefan Herms Maria Hipolito Per Hoffmann Dominic Holland Laura Huckins Stéphane Jamain Jessica S Johnson Anders Juréus Radhika Kandaswamy Robert Karlsson James L Kennedy Sarah Kittel-Schneider James A Knowles Manolis Kogevinas Anna C Koller Ralph Kupka Catharina Lavebratt Jacob Lawrence William B Lawson Markus Leber Phil H Lee Shawn E Levy Jun Z Li Chunyu Liu Susanne Lucae Anna Maaser Donald J MacIntyre Pamela B Mahon Wolfgang Maier Lina Martinsson Steve McCarroll Peter McGuffin Melvin G McInnis James D McKay Helena Medeiros Sarah E Medland Fan Meng Lili Milani Grant W Montgomery Derek W Morris Thomas W Mühleisen Niamh Mullins Hoang Nguyen Caroline M Nievergelt Annelie Nordin Adolfsson Evaristus A Nwulia Claire O'Donovan Loes M Olde Loohuis Anil P S Ori Lilijana Oruc Urban Ösby Roy H Perlis Amy Perry Andrea Pfennig James B Potash Shaun M Purcell Eline J Regeer Andreas Reif Céline S Reinbold John P Rice Fabio Rivas Margarita Rivera Panos Roussos Douglas M Ruderfer Euijung Ryu Cristina Sánchez-Mora Alan F Schatzberg William A Scheftner Nicholas J Schork Cynthia Shannon Weickert Tatyana Shehktman Paul D Shilling Engilbert Sigurdsson Claire Slaney Olav B Smeland Janet L Sobell Christine Søholm Hansen Anne T Spijker David St Clair Michael Steffens John S Strauss Fabian Streit Jana Strohmaier Szabolcs Szelinger Robert C Thompson Thorgeir E Thorgeirsson Jens Treutlein Helmut Vedder Weiqing Wang Stanley J Watson Thomas W Weickert Stephanie H Witt Simon Xi Wei Xu Allan H Young Peter Zandi Peng Zhang Sebastian Zöllner Rolf Adolfsson Ingrid Agartz Martin Alda Lena Backlund Bernhard T Baune Frank Bellivier Wade H Berrettini Joanna M Biernacka Douglas H R Blackwood Michael Boehnke Anders D Børglum Aiden Corvin Nicholas Craddock Mark J Daly Udo Dannlowski Tõnu Esko Bruno Etain Mark Frye Janice M Fullerton Elliot S Gershon Michael Gill Fernando Goes Maria Grigoroiu-Serbanescu Joanna Hauser David M Hougaard Christina M Hultman Ian Jones Lisa A Jones René S Kahn George Kirov Mikael Landén Marion Leboyer Cathryn M Lewis Qingqin S Li Jolanta Lissowska Nicholas G Martin Fermin Mayoral Susan L McElroy Andrew M McIntosh Francis J McMahon Ingrid Melle Andres Metspalu Philip B Mitchell Gunnar Morken Ole Mors Preben Bo Mortensen Bertram Müller-Myhsok Richard M Myers Benjamin M Neale Vishwajit Nimgaonkar Merete Nordentoft Markus M Nöthen Michael C O'Donovan Ketil J Oedegaard Michael J Owen Sara A Paciga Carlos Pato Michele T Pato Danielle Posthuma Josep Antoni Ramos-Quiroga Marta Ribasés Marcella Rietschel Guy A Rouleau Martin Schalling Peter R Schofield Thomas G Schulze Alessandro Serretti Jordan W Smoller Hreinn Stefansson Kari Stefansson Eystein Stordal Patrick F Sullivan Gustavo Turecki Arne E Vaaler Eduard Vieta John B Vincent Thomas Werge John I Nurnberger Naomi R Wray Arianna Di Florio Howard J Edenberg Sven Cichon Roel A Ophoff Laura J Scott Ole A Andreassen John Kelsoe Pamela Sklar

Nat Genet 2019 05 1;51(5):793-803. Epub 2019 May 1.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://www.nature.com/articles/s41588-019-0397-8
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http://dx.doi.org/10.1038/s41588-019-0397-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956732PMC
May 2019

Association Between Improvement in Baseline Mood and Long-Term Use of a Mindfulness and Meditation App: Observational Study.

JMIR Ment Health 2019 May 8;6(5):e12617. Epub 2019 May 8.

Department of Biomedial Informatics, University of California San Diego, San Diego, CA, United States.

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http://dx.doi.org/10.2196/12617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707590PMC
May 2019

Rare variant phasing using paired tumor:normal sequence data.

BMC Bioinformatics 2019 May 27;20(1):265. Epub 2019 May 27.

Human Biology Program, J. Craig Venter Institute, La Jolla, CA, USA.

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https://bmcbioinformatics.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12859-019-2753-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537421PMC
May 2019

Genetic risks and clinical rewards.

Nat Genet 2018 09;50(9):1210-1211

Department of Quantitative Medicine, The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.

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http://dx.doi.org/10.1038/s41588-018-0213-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383764PMC
September 2018

Randomized clinical trials and personalized medicine: A commentary on deaton and cartwright.

Soc Sci Med 2018 08 24;210:71-73. Epub 2018 Apr 24.

The Translational Genomics Research Institute (TGen), Phoenix, AZ, United States; The City of Hope/TGen IMPACT Center, Duarte, CA, United States; The J. Craig Venter Institute, La Jolla, CA, United States; The University of California, San Diego, La Jolla, CA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02779536183020
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http://dx.doi.org/10.1016/j.socscimed.2018.04.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388397PMC
August 2018

Personalized medicine: motivation, challenges, and progress.

Fertil Steril 2018 06;109(6):952-963

The Translational Genomics Research Institute, Phoenix, Arizona; The City of Hope/TGen IMPACT Center, Duarte, California; J. Craig Venter Institute, La Jolla, California; The University of California, San Diego, La Jolla, California. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2018.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366451PMC
June 2018

The big data revolution and human genetics.

Hum Mol Genet 2018 05;27(R1):R1

The Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1093/hmg/ddy123DOI Listing
May 2018

Effective discovery of rare variants by pooled target capture sequencing: A comparative analysis with individually indexed target capture sequencing.

Mutat Res 2018 05 30;809:24-31. Epub 2018 Mar 30.

Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, 10461, USA; Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00275107183004
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http://dx.doi.org/10.1016/j.mrfmmm.2018.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962423PMC
May 2018

Comparison of phasing strategies for whole human genomes.

PLoS Genet 2018 04 5;14(4):e1007308. Epub 2018 Apr 5.

J. Craig Venter Institute, La Jolla, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903673PMC
April 2018

Single-Subject Studies in Translational Nutrition Research.

Annu Rev Nutr 2017 08 17;37:395-422. Epub 2017 Jul 17.

J. Craig Venter Institute, La Jolla, California 92037; email:

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http://dx.doi.org/10.1146/annurev-nutr-071816-064717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383767PMC
August 2017

Whole genome sequence association and ancestry-informed polygenic profile of EEG alpha in a Native American population.

Am J Med Genet B Neuropsychiatr Genet 2017 Jun 24;174(4):435-450. Epub 2017 Apr 24.

Department of Neuroscience, The Scripps Research Institute, La Jolla, California.

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http://dx.doi.org/10.1002/ajmg.b.32533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435561PMC
June 2017

Comprehensive analysis of treatment response phenotypes in rheumatoid arthritis for pharmacogenetic studies.

Arthritis Res Ther 2017 05 12;19(1):90. Epub 2017 May 12.

Human Biology, J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, 92092, CA, USA.

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http://dx.doi.org/10.1186/s13075-017-1299-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427602PMC
May 2017

Genome-wide association study of paliperidone efficacy.

Pharmacogenet Genomics 2017 01;27(1):7-18

aNeuroscience, Janssen Research & Development, LLC bJanssen Scientific Affairs, LLC, Titusville cJanssen Research & Development, LLC, Raritan dBlue Note Biosciences, LLC, Princeton, New Jersey eBiostatistics and Bioinformatics, The Scripps Translational Science Institute fDepartment of Molecular and Experimental Medicine, The Scripps Research Institute gScripps Health hHuman Biology, J. Craig Venter Institute, La Jolla iMD Revolution, San Diego, California, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152628PMC
January 2017

Patient perspectives on whole-genome sequencing for undiagnosed diseases.

Per Med 2017 01 30;14(1):17-25. Epub 2016 Nov 30.

Scripps Translational Science Institute, Scripps Genomic Medicine, Scripps Health, La Jolla, CA, USA.

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http://dx.doi.org/10.2217/pme-2016-0050DOI Listing
January 2017

Mission critical: the need for proteomics in the era of next-generation sequencing and precision medicine.

Hum Mol Genet 2016 Oct 20;25(R2):R182-R189. Epub 2016 Jul 20.

MYi Diagnostics and Discovery J. Craig Venter Institute University of California, San Diego, La Jolla, CA, USA The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA

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http://dx.doi.org/10.1093/hmg/ddw214DOI Listing
October 2016

Common susceptibility variants are shared between schizophrenia and psoriasis in the Han Chinese population.

J Psychiatry Neurosci 2016 10;41(6):413-421

From the Institute of Dermatology, Department of Dermatology of The First Affiliated Hospital. Key lab of Dermatology Ministry of Education, Anhui Medical University, Hefei, China (Yin, Jiang, Wu, Cui, Shen, Cheng, Zhou, Chen, Zuo, Zhend, Fan, Wang, Sun, Yang, Zhang); the Institute of Dermatology, Huashan Hospital, Fudan University, Shanghai, China (Yin, Zhang, Huang, Xu, Zhang); the The Scripps Translational Science Institute, La Jolla, California, USA (Yin, Wineinger, Schork); the Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, USA (Yin, Schork); Human Biology, J. Craig Venter Institute, La Jolla, California, USA (Yin, Schork); the Department of Genetics, and Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, USA (Yin); the Scripps Health, La Jolla, California, USA (Wineinger); the Department of Neurology, the First Affiliated Hospital of Anhui Medical University, Hefei, China (Wang); the Peking University Sixth Hospital, Peking University Institute of Mental Health; Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China (Yue, Wang); the Peking University Sixth Hospital, Peking University Institute of Mental Health; Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China (Yue, Wang); the Human Genetics, Genome Institute of Singapore, Singapore (Norgren, Wang, Liu); the Institute of Mental Health, Singapore (Norgren, Wang, Liu); the Institute of Mental Health, Singapore (Lee); the Saw Swee Hock School of Public Health, National University of Singapore, Singapore 138672, Singapore (Tai, Liu).

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http://dx.doi.org/10.1503/jpn.150210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082512PMC
October 2016

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.

Authors:
Liping Hou Sarah E Bergen Nirmala Akula Jie Song Christina M Hultman Mikael Landén Mazda Adli Martin Alda Raffaella Ardau Bárbara Arias Jean-Michel Aubry Lena Backlund Judith A Badner Thomas B Barrett Michael Bauer Bernhard T Baune Frank Bellivier Antonio Benabarre Susanne Bengesser Wade H Berrettini Abesh Kumar Bhattacharjee Joanna M Biernacka Armin Birner Cinnamon S Bloss Clara Brichant-Petitjean Elise T Bui William Byerley Pablo Cervantes Caterina Chillotti Sven Cichon Francesc Colom William Coryell David W Craig Cristiana Cruceanu Piotr M Czerski Tony Davis Alexandre Dayer Franziska Degenhardt Maria Del Zompo J Raymond DePaulo Howard J Edenberg Bruno Étain Peter Falkai Tatiana Foroud Andreas J Forstner Louise Frisén Mark A Frye Janice M Fullerton Sébastien Gard Julie S Garnham Elliot S Gershon Fernando S Goes Tiffany A Greenwood Maria Grigoroiu-Serbanescu Joanna Hauser Urs Heilbronner Stefanie Heilmann-Heimbach Stefan Herms Maria Hipolito Shashi Hitturlingappa Per Hoffmann Andrea Hofmann Stephane Jamain Esther Jiménez Jean-Pierre Kahn Layla Kassem John R Kelsoe Sarah Kittel-Schneider Sebastian Kliwicki Daniel L Koller Barbara König Nina Lackner Gonzalo Laje Maren Lang Catharina Lavebratt William B Lawson Marion Leboyer Susan G Leckband Chunyu Liu Anna Maaser Pamela B Mahon Wolfgang Maier Mario Maj Mirko Manchia Lina Martinsson Michael J McCarthy Susan L McElroy Melvin G McInnis Rebecca McKinney Philip B Mitchell Marina Mitjans Francis M Mondimore Palmiero Monteleone Thomas W Mühleisen Caroline M Nievergelt Markus M Nöthen Tomas Novák John I Nurnberger Evaristus A Nwulia Urban Ösby Andrea Pfennig James B Potash Peter Propping Andreas Reif Eva Reininghaus John Rice Marcella Rietschel Guy A Rouleau Janusz K Rybakowski Martin Schalling William A Scheftner Peter R Schofield Nicholas J Schork Thomas G Schulze Johannes Schumacher Barbara W Schweizer Giovanni Severino Tatyana Shekhtman Paul D Shilling Christian Simhandl Claire M Slaney Erin N Smith Alessio Squassina Thomas Stamm Pavla Stopkova Fabian Streit Jana Strohmaier Szabolcs Szelinger Sarah K Tighe Alfonso Tortorella Gustavo Turecki Eduard Vieta Julia Volkert Stephanie H Witt Adam Wright Peter P Zandi Peng Zhang Sebastian Zollner Francis J McMahon

Hum Mol Genet 2016 08 21;25(15):3383-3394. Epub 2016 Jun 21.

Intramural Research Program, National Institute of Mental Health, National Institutes of Health,U.S. Department of Health & Human Services, Bethesda, MD, USA,

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http://dx.doi.org/10.1093/hmg/ddw181DOI Listing
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August 2016

p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish.

Proc Natl Acad Sci U S A 2016 07 8;113(30):8460-5. Epub 2016 Jul 8.

The Scripps Laboratories for tRNA Synthetase Research, The Scripps Research Institute, La Jolla, CA 92037; Department of Cell and Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037; Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037; Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33458;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968768PMC
July 2016

Epigenomic Diversity in a Global Collection of Arabidopsis thaliana Accessions.

Cell 2016 Jul;166(2):492-505

Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.06.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172462PMC
July 2016

A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese.

PLoS One 2015 1;10(5):e0125369. Epub 2015 May 1.

Institute of Dermatology, Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui Province, China; Key lab of Dermatology, Ministry of Education, State Key Lab of Dermatology Incubation Center, Anhui Medical University, Hefei, Anhui Province, China; Key Lab of Gene Resource Utilization for Complex Diseases, Hefei, Anhui Province, China; Collaborative Innovation Center for Complex and Severe Dermatosis, Anhui Medical University, Hefei, Anhui Province, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416725PMC
February 2016

Whole-genome mutational burden analysis of three pluripotency induction methods.

Nat Commun 2016 Feb 19;7:10536. Epub 2016 Feb 19.

The Scripps Research Institute, Department of Chemical Physiology, Center for Regenerative Medicine, La Jolla, California 92037 USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762882PMC
February 2016

Partial Least Squares Regression Can Aid in Detecting Differential Abundance of Multiple Features in Sets of Metagenomic Samples.

Front Genet 2015 17;6:350. Epub 2015 Dec 17.

Department of Human Biology, J. Craig Venter InstituteLa Jolla, CA, USA; Departments of Psychiatry and Family Medicine and Public Health, University of California, San DiegoLa Jolla, CA, USA.

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http://dx.doi.org/10.3389/fgene.2015.00350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681790PMC
January 2016

Scripps Genome ADVISER: Annotation and Distributed Variant Interpretation SERver.

PLoS One 2015 23;10(2):e0116815. Epub 2015 Feb 23.

Scripps Health, La Jolla, CA 92037, United States of America; The Scripps Translational Science Institute, La Jolla, CA 92037, United States of America; The Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, United States of America; Cypher Genomics, Inc., La Jolla, CA 92037, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338027PMC
December 2015

Variants Near CCK Receptors are Associated With Electrophysiological Responses to Pre-pulse Startle Stimuli in a Mexican American Cohort.

Twin Res Hum Genet 2015 Dec 26;18(6):727-37. Epub 2015 Nov 26.

Department of Molecular and Cellular Neuroscience,The Scripps Research Institute,La Jolla,CA,USA.

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http://dx.doi.org/10.1017/thg.2015.77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727900PMC
December 2015

Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3'-Untranslated Region Polymorphism C+87T by MicroRNA-107.

J Am Soc Nephrol 2015 Aug 12;26(8):1816-25. Epub 2014 Nov 12.

Departments of Medicine, Veterans Affairs San Diego Healthcare System, San Diego, California Institute for Genomic Medicine, University of California at San Diego, La Jolla, California; Pharmacology and.

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http://dx.doi.org/10.1681/ASN.2014060537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520173PMC
August 2015

Modeling the 3D geometry of the cortical surface with genetic ancestry.

Curr Biol 2015 Aug 9;25(15):1988-92. Epub 2015 Jul 9.

Department of Cognitive Science, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Multimodal Imaging Laboratory, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA; Department of Radiology, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA; Department of Neuroscience, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA; Department of Psychiatry, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786069PMC
August 2015

Family income, parental education and brain structure in children and adolescents.

Nat Neurosci 2015 May 30;18(5):773-8. Epub 2015 Mar 30.

1] The Saban Research Institute of Children's Hospital, Los Angeles, California, USA. [2] Department of Pediatrics of the Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [3] The Pediatric Imaging, Neurocognition, and Genetics Study, San Diego, California, USA.

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May 2015

Characteristics of genomic test consumers who spontaneously share results with their health care provider.

Health Commun 2014 5;29(1):105-8. Epub 2013 Feb 5.

a Scripps Genomic Medicine , Scripps Translational Science Institute, Scripps Health.

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http://dx.doi.org/10.1080/10410236.2012.717216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679226PMC
April 2015

Personalized medicine: Time for one-person trials.

Nature 2015 Apr;520(7549):609-11

J. Craig Venter Institute in La Jolla, California, USA. He is also professor at the University of California, San Diego, and at the Translational Genomics Research Institute (TGen) in Phoenix, Arizona, USA.

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April 2015

Admixture and clinical phenotypic variation.

Hum Hered 2014 29;77(1-4):73-86. Epub 2014 Jul 29.

The Scripps Translational Science Institute, La Jolla, Calif., USA.

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March 2015

Functional expression of dental plaque microbiota.

Front Cell Infect Microbiol 2014 14;4:108. Epub 2014 Aug 14.

Department of Cariology and Comprehensive Care, College of Dentistry, New York University New York, NY, USA.

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http://dx.doi.org/10.3389/fcimb.2014.00108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132376PMC
March 2015

Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.

Psychoneuroendocrinology 2015 Jan 30;51:459-71. Epub 2014 Oct 30.

VA Center of Excellence for Stress and Mental Health (CESAMH), VA San Diego Healthcare System, La Jolla, CA 92161, USA; Department of Psychiatry, School of Medicine, University of California at San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.psyneuen.2014.10.017DOI Listing
January 2015

Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence.

Oncotarget 2015 Jan;6(1):547-55

College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA. Department of Head and Neck Surgery, Greater Poland Cancer Centre, Poznan University of Medical Sciences, Poznan, Poland.

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http://dx.doi.org/10.18632/oncotarget.2772DOI Listing
January 2015

Correlation analysis of genetic admixture and social identification with body mass index in a Native American community.

Am J Hum Biol 2014 May-Jun;26(3):347-60. Epub 2014 Feb 17.

Scripps Translational Science Institute and The Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, 92037.

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http://dx.doi.org/10.1002/ajhb.22521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068510PMC
December 2014

Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol-related phenotypes in a Native American community sample.

Am J Med Genet B Neuropsychiatr Genet 2014 Dec 30;165B(8):673-83. Epub 2014 Sep 30.

Department of Human Biology, J. Craig Venter Institute, La Jolla, California; Scripps Translational Science Institute, The Scripps Research Institute, La Jolla, California.

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http://dx.doi.org/10.1002/ajmg.b.32272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364382PMC
December 2014

Expression levels of insulin-like growth factors 1 and 2 in head and neck squamous cell carcinoma.

Growth Horm IGF Res 2014 Aug 22;24(4):137-41. Epub 2014 Apr 22.

College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ghir.2014.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083007PMC
August 2014

Characterization of genetic variation in the VGLL4 gene in anorexia nervosa.

Psychiatr Genet 2014 Aug;24(4):183-4

aDepartment of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia bDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania cDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland dDepartment of Psychiatry, University of Minnesota, Minneapolis, Minnesota eNew York Presbyterian Hospital-Westchester Division, Weill Medical College of Cornell, University, White Plains, New York fEating Recovery Center, Denver, Colorado gDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina hNeuropsychiatric Research Institute, Fargo iDepartment of Clinical Neuroscience, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota jDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles kCenter for Health Sciences, SRI International, Menlo Park lDepartment of Psychiatry, University of California at San Diego, San Diego mScripps Genomic Medicine, The Scripps Research Institute, La Jolla, California nDepartment of Psychology, Florida State University, Tallahassee, Florida oDepartment of Psychology, Michigan State University, East Lansing, Michigan pClinical Psychology Program, American School of Professional Psychology at Argosy University, Washington, District of Columbia, USA qRoseneck Hospital for Behavioral Medicine, Prien rDepartment of Psychiatry, University of Munich (LMU), Munich, Germany sCenter for Addiction and Mental Health tDepartment of Psychiatry, Toronto General Hospital, University Health Network uDepartment of Psychiatry, University of Toronto, Toronto, Ontario, Canada vDepartment of Psychiatry, Neurobiology, Pharmacology, and Biotechnology, University of Pisa, Pisa, Italy wDepartment of Academic Psychiatry, Bermondsey Wing Guys Hospital, University of London, London, UK xBrain Mind Institute EPFL - Lausanne and Center for Psyc

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August 2014

A high resolution case study of a patient with recurrent Plasmodium vivax infections shows that relapses were caused by meiotic siblings.

PLoS Negl Trop Dis 2014 Jun 5;8(6):e2882. Epub 2014 Jun 5.

Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046966PMC
June 2014

Genetic parts to a preventive medicine whole.

Genome Med 2013 27;5(6):54. Epub 2013 Jun 27.

Department of Molecular and Experimental Medicine and the Scripps Translational Science Institute, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1186/gm458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706981PMC
May 2014

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations.

Hum Mol Genet 2014 May 17;23(9):2498-510. Epub 2013 Dec 17.

Gillings School of Global Public Health.

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http://dx.doi.org/10.1093/hmg/ddt626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988452PMC
May 2014

Mechanisms of linezolid resistance among coagulase-negative staphylococci determined by whole-genome sequencing.

mBio 2014 May 13;5(3):e00894-14. Epub 2014 May 13.

UCLA David Geffen School of Medicine, Department of Pathology and Laboratory Medicine, Los Angeles, California, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030478PMC
May 2014

A pharmacological network for lifespan extension in Caenorhabditis elegans.

Aging Cell 2014 Apr 13;13(2):206-15. Epub 2013 Nov 13.

Division of Basic Sciences, Fred Hutchison Cancer Research Center, Howard Hughes Medical Institute, Seattle, WA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955372PMC
April 2014

Genetic implication of a novel thiamine transporter in human hypertension.

J Am Coll Cardiol 2014 Apr 5;63(15):1542-55. Epub 2014 Feb 5.

Department of Medicine, University of California at San Diego (UCSD), La Jolla, California; Veterans Affairs San Diego Healthcare System, San Diego, California; Department of Pharmacology and the Institute for Genomic Medicine, UCSD, La Jolla, California. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992204PMC
April 2014

Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected].

J Am Coll Cardiol 2014 Feb 16;63(4):358-68. Epub 2013 Oct 16.

Department of Medicine, University of California at San Diego, San Diego, California; Institute for Genomic Medicine, University of California at San Diego, San Diego, California; Department of Pharmacology, University of California at San Diego, San Diego, California; VA San Diego Healthcare System, San Diego, California. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946708PMC
February 2014

Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines.

JAMA Psychiatry 2014 Feb;71(2):149-57

Department of Psychiatry, Veterans Affairs San Diego Healthcare System, San Diego, California2Veterans Affairs Center of Excellence for Stress and Mental Health, San Diego, California7Department of Psychiatry, School of Medicine, University of California.

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February 2014

Direct-to-consumer pharmacogenomic testing is associated with increased physician utilisation.

J Med Genet 2014 Feb 16;51(2):83-9. Epub 2013 Dec 16.

Scripps Genomic Medicine, Scripps Translational Science Institute, and Scripps Health, La Jolla, California, USA.

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February 2014

Treatment responses to tooth whitening in twins.

Twin Res Hum Genet 2014 Feb 16;17(1):23-6. Epub 2014 Jan 16.

New York University College of Dentistry, New York, NY, USA.

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February 2014

Utility of network integrity methods in therapeutic target identification.

Front Genet 2014 3;5:12. Epub 2014 Feb 3.

Department of Molecular and Experimental Medicine, The Scripps Research Institute La Jolla, CA, USA ; Scripps Genomic Medicine, The Scripps Translational Science Institute La Jolla, CA, USA.

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http://dx.doi.org/10.3389/fgene.2014.00012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909879PMC
February 2014

Common variants explain a large fraction of the variability in the liability to psoriasis in a Han Chinese population.

BMC Genomics 2014 Jan 30;15:87. Epub 2014 Jan 30.

Institute of Dermatology, Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui Province 230032, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909441PMC
January 2014

The dental plaque microbiome in health and disease.

PLoS One 2013 8;8(3):e58487. Epub 2013 Mar 8.

J. Craig Venter Institute, Rockville, Maryland, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592792PMC
September 2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Authors:
S Hong Lee Stephan Ripke Benjamin M Neale Stephen V Faraone Shaun M Purcell Roy H Perlis Bryan J Mowry Anita Thapar Michael E Goddard John S Witte Devin Absher Ingrid Agartz Huda Akil Farooq Amin Ole A Andreassen Adebayo Anjorin Richard Anney Verneri Anttila Dan E Arking Philip Asherson Maria H Azevedo Lena Backlund Judith A Badner Anthony J Bailey Tobias Banaschewski Jack D Barchas Michael R Barnes Thomas B Barrett Nicholas Bass Agatino Battaglia Michael Bauer Mònica Bayés Frank Bellivier Sarah E Bergen Wade Berrettini Catalina Betancur Thomas Bettecken Joseph Biederman Elisabeth B Binder Donald W Black Douglas H R Blackwood Cinnamon S Bloss Michael Boehnke Dorret I Boomsma Gerome Breen René Breuer Richard Bruggeman Paul Cormican Nancy G Buccola Jan K Buitelaar William E Bunney Joseph D Buxbaum William F Byerley Enda M Byrne Sian Caesar Wiepke Cahn Rita M Cantor Miguel Casas Aravinda Chakravarti Kimberly Chambert Khalid Choudhury Sven Cichon C Robert Cloninger David A Collier Edwin H Cook Hilary Coon Bru Cormand Aiden Corvin William H Coryell David W Craig Ian W Craig Jennifer Crosbie Michael L Cuccaro David Curtis Darina Czamara Susmita Datta Geraldine Dawson Richard Day Eco J De Geus Franziska Degenhardt Srdjan Djurovic Gary J Donohoe Alysa E Doyle Jubao Duan Frank Dudbridge Eftichia Duketis Richard P Ebstein Howard J Edenberg Josephine Elia Sean Ennis Bruno Etain Ayman Fanous Anne E Farmer I Nicol Ferrier Matthew Flickinger Eric Fombonne Tatiana Foroud Josef Frank Barbara Franke Christine Fraser Robert Freedman Nelson B Freimer Christine M Freitag Marion Friedl Louise Frisén Louise Gallagher Pablo V Gejman Lyudmila Georgieva Elliot S Gershon Daniel H Geschwind Ina Giegling Michael Gill Scott D Gordon Katherine Gordon-Smith Elaine K Green Tiffany A Greenwood Dorothy E Grice Magdalena Gross Detelina Grozeva Weihua Guan Hugh Gurling Lieuwe De Haan Jonathan L Haines Hakon Hakonarson Joachim Hallmayer Steven P Hamilton Marian L Hamshere Thomas F Hansen Annette M Hartmann Martin Hautzinger Andrew C Heath Anjali K Henders Stefan Herms Ian B Hickie Maria Hipolito Susanne Hoefels Peter A Holmans Florian Holsboer Witte J Hoogendijk Jouke-Jan Hottenga Christina M Hultman Vanessa Hus Andrés Ingason Marcus Ising Stéphane Jamain Edward G Jones Ian Jones Lisa Jones Jung-Ying Tzeng Anna K Kähler René S Kahn Radhika Kandaswamy Matthew C Keller James L Kennedy Elaine Kenny Lindsey Kent Yunjung Kim George K Kirov Sabine M Klauck Lambertus Klei James A Knowles Martin A Kohli Daniel L Koller Bettina Konte Ania Korszun Lydia Krabbendam Robert Krasucki Jonna Kuntsi Phoenix Kwan Mikael Landén Niklas Långström Mark Lathrop Jacob Lawrence William B Lawson Marion Leboyer David H Ledbetter Phil H Lee Todd Lencz Klaus-Peter Lesch Douglas F Levinson Cathryn M Lewis Jun Li Paul Lichtenstein Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Chunyu Liu Falk W Lohoff Sandra K Loo Catherine Lord Jennifer K Lowe Susanne Lucae Donald J MacIntyre Pamela A F Madden Elena Maestrini Patrik K E Magnusson Pamela B Mahon Wolfgang Maier Anil K Malhotra Shrikant M Mane Christa L Martin Nicholas G Martin Manuel Mattheisen Keith Matthews Morten Mattingsdal Steven A McCarroll Kevin A McGhee James J McGough Patrick J McGrath Peter McGuffin Melvin G McInnis Andrew McIntosh Rebecca McKinney Alan W McLean Francis J McMahon William M McMahon Andrew McQuillin Helena Medeiros Sarah E Medland Sandra Meier Ingrid Melle Fan Meng Jobst Meyer Christel M Middeldorp Lefkos Middleton Vihra Milanova Ana Miranda Anthony P Monaco Grant W Montgomery Jennifer L Moran Daniel Moreno-De-Luca Gunnar Morken Derek W Morris Eric M Morrow Valentina Moskvina Pierandrea Muglia Thomas W Mühleisen Walter J Muir Bertram Müller-Myhsok Michael Murtha Richard M Myers Inez Myin-Germeys Michael C Neale Stan F Nelson Caroline M Nievergelt Ivan Nikolov Vishwajit Nimgaonkar Willem A Nolen Markus M Nöthen John I Nurnberger Evaristus A Nwulia Dale R Nyholt Colm O'Dushlaine Robert D Oades Ann Olincy Guiomar Oliveira Line Olsen Roel A Ophoff Urban Osby Michael J Owen Aarno Palotie Jeremy R Parr Andrew D Paterson Carlos N Pato Michele T Pato Brenda W Penninx Michele L Pergadia Margaret A Pericak-Vance Benjamin S Pickard Jonathan Pimm Joseph Piven Danielle Posthuma James B Potash Fritz Poustka Peter Propping Vinay Puri Digby J Quested Emma M Quinn Josep Antoni Ramos-Quiroga Henrik B Rasmussen Soumya Raychaudhuri Karola Rehnström Andreas Reif Marta Ribasés John P Rice Marcella Rietschel Kathryn Roeder Herbert Roeyers Lizzy Rossin Aribert Rothenberger Guy Rouleau Douglas Ruderfer Dan Rujescu Alan R Sanders Stephan J Sanders Susan L Santangelo Joseph A Sergeant Russell Schachar Martin Schalling Alan F Schatzberg William A Scheftner Gerard D Schellenberg Stephen W Scherer Nicholas J Schork Thomas G Schulze Johannes Schumacher Markus Schwarz Edward Scolnick Laura J Scott Jianxin Shi Paul D Shilling Stanley I Shyn Jeremy M Silverman Susan L Slager Susan L Smalley Johannes H Smit Erin N Smith Edmund J S Sonuga-Barke David St Clair Matthew State Michael Steffens Hans-Christoph Steinhausen John S Strauss Jana Strohmaier T Scott Stroup James S Sutcliffe Peter Szatmari Szabocls Szelinger Srinivasa Thirumalai Robert C Thompson Alexandre A Todorov Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Jim Van Os Astrid M Vicente Veronica J Vieland John B Vincent Peter M Visscher Christopher A Walsh Thomas H Wassink Stanley J Watson Myrna M Weissman Thomas Werge Thomas F Wienker Ellen M Wijsman Gonneke Willemsen Nigel Williams A Jeremy Willsey Stephanie H Witt Wei Xu Allan H Young Timothy W Yu Stanley Zammit Peter P Zandi Peng Zhang Frans G Zitman Sebastian Zöllner Bernie Devlin John R Kelsoe Pamela Sklar Mark J Daly Michael C O'Donovan Nicholas Craddock Patrick F Sullivan Jordan W Smoller Kenneth S Kendler Naomi R Wray

Nat Genet 2013 Sep 11;45(9):984-94. Epub 2013 Aug 11.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800159PMC
September 2013

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.

Authors:
Nora Franceschini Ervin Fox Zhaogong Zhang Todd L Edwards Michael A Nalls Yun Ju Sung Bamidele O Tayo Yan V Sun Omri Gottesman Adebawole Adeyemo Andrew D Johnson J Hunter Young Ken Rice Qing Duan Fang Chen Yun Li Hua Tang Myriam Fornage Keith L Keene Jeanette S Andrews Jennifer A Smith Jessica D Faul Zhang Guangfa Wei Guo Yu Liu Sarah S Murray Solomon K Musani Sathanur Srinivasan Digna R Velez Edwards Heming Wang Lewis C Becker Pascal Bovet Murielle Bochud Ulrich Broeckel Michel Burnier Cara Carty Daniel I Chasman Georg Ehret Wei-Min Chen Guanjie Chen Wei Chen Jingzhong Ding Albert W Dreisbach Michele K Evans Xiuqing Guo Melissa E Garcia Rich Jensen Margaux F Keller Guillaume Lettre Vaneet Lotay Lisa W Martin Jason H Moore Alanna C Morrison Thomas H Mosley Adesola Ogunniyi Walter Palmas George Papanicolaou Alan Penman Joseph F Polak Paul M Ridker Babatunde Salako Andrew B Singleton Daniel Shriner Kent D Taylor Ramachandran Vasan Kerri Wiggins Scott M Williams Lisa R Yanek Wei Zhao Alan B Zonderman Diane M Becker Gerald Berenson Eric Boerwinkle Erwin Bottinger Mary Cushman Charles Eaton Fredrik Nyberg Gerardo Heiss Joel N Hirschhron Virginia J Howard Konrad J Karczewsk Matthew B Lanktree Kiang Liu Yongmei Liu Ruth Loos Karen Margolis Michael Snyder Bruce M Psaty Nicholas J Schork David R Weir Charles N Rotimi Michele M Sale Tamara Harris Sharon L R Kardia Steven C Hunt Donna Arnett Susan Redline Richard S Cooper Neil J Risch D C Rao Jerome I Rotter Aravinda Chakravarti Alex P Reiner Daniel Levy Brendan J Keating Xiaofeng Zhu

Am J Hum Genet 2013 Sep 22;93(3):545-54. Epub 2013 Aug 22.

Department of Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.ajhg.2013.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769920PMC
September 2013

Impact of direct-to-consumer genomic testing at long term follow-up.

J Med Genet 2013 Jun 4;50(6):393-400. Epub 2013 Apr 4.

Scripps Genomic Medicine, Scripps Translational Science Institute, 3344 N. Torrey Pines Court, Suite 300, La Jolla, CA 92037, USA.

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June 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

Authors:
Santhi K Ganesh Vinicius Tragante Wei Guo Yiran Guo Matthew B Lanktree Erin N Smith Toby Johnson Berta Almoguera Castillo John Barnard Jens Baumert Yen-Pei Christy Chang Clara C Elbers Martin Farrall Mary E Fischer Nora Franceschini Tom R Gaunt Johannes M I H Gho Christian Gieger Yan Gong Aaron Isaacs Marcus E Kleber Irene Mateo Leach Caitrin W McDonough Matthijs F L Meijs Olle Mellander Cliona M Molony Ilja M Nolte Sandosh Padmanabhan Tom S Price Ramakrishnan Rajagopalan Jonathan Shaffer Sonia Shah Haiqing Shen Nicole Soranzo Peter J van der Most Erik P A Van Iperen Jessica Van Setten Jessic A Van Setten Judith M Vonk Li Zhang Amber L Beitelshees Gerald S Berenson Deepak L Bhatt Jolanda M A Boer Eric Boerwinkle Ben Burkley Amber Burt Aravinda Chakravarti Wei Chen Rhonda M Cooper-Dehoff Sean P Curtis Albert Dreisbach David Duggan Georg B Ehret Richard R Fabsitz Myriam Fornage Ervin Fox Clement E Furlong Ron T Gansevoort Marten H Hofker G Kees Hovingh Susan A Kirkland Kandice Kottke-Marchant Abdullah Kutlar Andrea Z Lacroix Taimour Y Langaee Yun R Li Honghuang Lin Kiang Liu Steffi Maiwald Rainer Malik Gurunathan Murugesan Christopher Newton-Cheh Jeffery R O'Connell N Charlotte Onland-Moret Willem H Ouwehand Walter Palmas Brenda W Penninx Carl J Pepine Mary Pettinger Joseph F Polak Vasan S Ramachandran Jane Ranchalis Susan Redline Paul M Ridker Lynda M Rose Hubert Scharnag Nicholas J Schork Daichi Shimbo Alan R Shuldiner Sathanur R Srinivasan Ronald P Stolk Herman A Taylor Barbara Thorand Mieke D Trip Cornelia M van Duijn W Monique Verschuren Cisca Wijmenga Bernhard R Winkelmann Sharon Wyatt J Hunter Young Bernhard O Boehm Mark J Caulfield Daniel I Chasman Karina W Davidson Pieter A Doevendans Garret A Fitzgerald John G Gums Hakon Hakonarson Hans L Hillege Thomas Illig Gail P Jarvik Julie A Johnson John J P Kastelein Wolfgang Koenig Winfried März Braxton D Mitchell Sarah S Murray Albertine J Oldehinkel Daniel J Rader Muredach P Reilly Alex P Reiner Eric E Schadt Roy L Silverstein Harold Snieder Alice V Stanton André G Uitterlinden Pim van der Harst Yvonne T van der Schouw Nilesh J Samani Andrew D Johnson Patricia B Munroe Paul I W de Bakker Xiaofeng Zhu Daniel Levy Brendan J Keating Folkert W Asselbergs

Hum Mol Genet 2013 Apr 8;22(8):1663-78. Epub 2013 Jan 8.

Division of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, MI, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657476PMC
April 2013

Patterns of population epigenomic diversity.

Nature 2013 Mar 6;495(7440):193-8. Epub 2013 Mar 6.

Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature11968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798000PMC
March 2013

A Method for Inferring an Individual's Genetic Ancestry and Degree of Admixture Associated with Six Major Continental Populations.

Front Genet 2012 14;3:322. Epub 2013 Jan 14.

Department of Molecular and Experimental Medicine, The Scripps Research Institute and the Scripps Translational Science Institute La Jolla, CA, USA.

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http://dx.doi.org/10.3389/fgene.2012.00322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543981PMC
January 2013