Nicholas J Maragakis

Nicholas J Maragakis

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Nicholas J Maragakis

Publications by authors named "Nicholas J Maragakis"

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Focal and dose-dependent neuroprotection in ALS mice following AAV2-neurturin delivery.

Exp Neurol 2019 Oct 31;323:113091. Epub 2019 Oct 31.

Department of Neurology, Johns Hopkins University, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2019.113091DOI Listing
October 2019

Perfluorocarbon Labeling of Human Glial-Restricted Progenitors for F Magnetic Resonance Imaging.

Stem Cells Transl Med 2019 04 7;8(4):355-365. Epub 2019 Jan 7.

Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://doi.wiley.com/10.1002/sctm.18-0094
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http://dx.doi.org/10.1002/sctm.18-0094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431733PMC
April 2019

Motoneuron Disease: Basic Science.

Adv Neurobiol 2017 ;15:163-190

Department of Neurology, Johns Hopkins University, 855 N. Wolfe St., Rm 248, Baltimore, MD, 21205, USA.

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http://link.springer.com/10.1007/978-3-319-57193-5_6
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http://dx.doi.org/10.1007/978-3-319-57193-5_6DOI Listing
November 2018

Motoneuron Disease: Clinical.

Adv Neurobiol 2017 ;15:191-210

Department of Neurology, Johns Hopkins University, 855 N. Wolfe St., Rm 248, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1007/978-3-319-57193-5_7DOI Listing
November 2018

Current and emerging ALS biomarkers: utility and potential in clinical trials.

Expert Rev Neurother 2018 Nov 8;18(11):871-886. Epub 2018 Oct 8.

a School of Medicine , Johns Hopkins University , Baltimore , MD , USA.

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http://dx.doi.org/10.1080/14737175.2018.1530987DOI Listing
November 2018

Olfactory dysfunction in amyotrophic lateral sclerosis.

Ann Clin Transl Neurol 2018 Aug 19;5(8):976-981. Epub 2018 Jun 19.

School of Medicine Johns Hopkins University Baltimore Maryland.

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http://dx.doi.org/10.1002/acn3.594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093848PMC
August 2018

A stocked toolbox for understanding the role of astrocytes in disease.

Nat Rev Neurol 2018 06;14(6):351-362

Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41582-018-0010-2DOI Listing
June 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

What can we learn from the edaravone development program for ALS?

Amyotroph Lateral Scler Frontotemporal Degener 2017 Oct;18(sup1):98-103

a School of Medicine , Johns Hopkins University , Baltimore , MD , USA.

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http://dx.doi.org/10.1080/21678421.2017.1361446DOI Listing
October 2017

Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo.

Stem Cell Reports 2017 04 30;8(4):843-855. Epub 2017 Mar 30.

Waisman Center, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705, USA; Departments of Neuroscience and Neurology, University of Wisconsin, Madison, WI 53705, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711173009
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http://dx.doi.org/10.1016/j.stemcr.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390239PMC
April 2017

Serial in vivo imaging of transplanted allogeneic neural stem cell survival in a mouse model of amyotrophic lateral sclerosis.

Exp Neurol 2017 03 28;289:96-102. Epub 2016 Dec 28.

Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Cellular Imaging Section and Vascular Biology Program, Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Chemical & Biomolecular Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2016.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285319PMC
March 2017

Erratum.

Adv Neurobiol 2017 ;15:E1

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1007/978-3-319-57193-5_21DOI Listing
January 2017

Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.

Glia 2016 07 16;64(7):1154-69. Epub 2016 Apr 16.

Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/glia.22989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635605PMC
July 2016

A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells.

PLoS One 2015 11;10(3):e0118266. Epub 2015 Mar 11.

Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, 21205, United States of America; Brain Science Institute, Johns Hopkins University, Baltimore, Maryland, 21205, United States of America; Department of Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, Maryland, 21205, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118266PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356618PMC
December 2015

Neural and glial progenitor transplantation as a neuroprotective strategy for Amyotrophic Lateral Sclerosis (ALS).

Brain Res 2015 Dec 14;1628(Pt B):343-350. Epub 2015 Jul 14.

Department of Neurology, Johns Hopkins University, 250.10 Rangos Building, 855 North Wolfe St., Baltimore, MD 21205, United States. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2015.06.035DOI Listing
December 2015

Hemiparetic Primary Lateral Sclerosis: Revisiting Mills Syndrome.

Case Rep Neurol 2015 Sep-Dec;7(3):191-5. Epub 2013 Sep 24.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Md., USA.

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http://dx.doi.org/10.1159/000440713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611067PMC
October 2015

Human iPS cell-derived astrocyte transplants preserve respiratory function after spinal cord injury.

Exp Neurol 2015 Sep 26;271:479-92. Epub 2015 Jul 26.

Department of Neuroscience, Farber Institute for Neurosciences, Sidney Kimmel Medical College at Thomas Jefferson University, 900 Walnut Street, JHN 469, Philadelphia, PA 19107, United States. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2015.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586993PMC
September 2015

Induced pluripotent stem cells from ALS patients for disease modeling.

Brain Res 2015 May 16;1607:15-25. Epub 2014 Sep 16.

Johns Hopkins University, School of Medicine, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2014.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362997PMC
May 2015

Transplantation of glial progenitors that overexpress glutamate transporter GLT1 preserves diaphragm function following cervical SCI.

Mol Ther 2015 Mar 10;23(3):533-48. Epub 2014 Dec 10.

Department of Neuroscience, Farber Institute for Neurosciences, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/mt.2014.236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351463PMC
March 2015

Human glial progenitor engraftment and gene expression is independent of the ALS environment.

Exp Neurol 2015 Feb 16;264:188-99. Epub 2014 Dec 16.

Department of Neurology, Johns Hopkins University, 250.10 Rangos Building, 855 North Wolfe St., Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2014.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411013PMC
February 2015

Gene profiling of human induced pluripotent stem cell-derived astrocyte progenitors following spinal cord engraftment.

Stem Cells Transl Med 2014 May 6;3(5):575-85. Epub 2014 Mar 6.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Departments of Rehabilitation and Regenerative Medicine, Pathology and Cell Biology, Neurology, and Neuroscience, Center for Motor Neuron Biology and Disease, Columbia Stem Cell Initiative, Columbia University Medical Center, New York, New York, Stem Cell Laboratory for CNS Disease Modeling-MultiPark, Department of Experimental Medical Science, Lund University, Lund, Sweden; Howard Hughes Medical Institute, Harvard Stem Cell Institute and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.5966/sctm.2013-0153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006486PMC
May 2014

Electrical impedance myography correlates with standard measures of ALS severity.

Muscle Nerve 2014 Mar 19;49(3):441-3. Epub 2013 Dec 19.

Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, TCC-810, Boston, Massachusetts, USA, 02215.

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http://dx.doi.org/10.1002/mus.24128DOI Listing
March 2014

C9orf72 nucleotide repeat structures initiate molecular cascades of disease.

Nature 2014 Mar 5;507(7491):195-200. Epub 2014 Mar 5.

1] Department of Biochemistry and Molecular Biology, Johns Hopkins University Baltimore, Maryland 21205, USA [2] Department of Neuroscience, Johns Hopkins University Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1038/nature13124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046618PMC
March 2014

Altered astrocytic expression of TDP-43 does not influence motor neuron survival.

Exp Neurol 2013 Dec 9;250:250-9. Epub 2013 Oct 9.

Department of Neurology, Johns Hopkins University School of Medicine, Rangos 248, 855 North Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.expneurol.2013.10.004DOI Listing
December 2013

Glia: an emerging target for neurological disease therapy.

Stem Cell Res Ther 2012 Sep 28;3(5):37. Epub 2012 Sep 28.

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http://dx.doi.org/10.1186/scrt128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580428PMC
September 2012

Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS.

Neurobiol Dis 2012 Aug 11;47(2):194-200. Epub 2012 Apr 11.

Weinberg Unit for ALS Research, Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.nbd.2012.03.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367047PMC
August 2012

Selected statins produce rapid spinal motor neuron loss in vitro.

BMC Musculoskelet Disord 2012 Jun 15;13:100. Epub 2012 Jun 15.

Department of Neurology, Johns Hopkins School of Medicine, Baltimore, USA.

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http://dx.doi.org/10.1186/1471-2474-13-100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487793PMC
June 2012

Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury.

Glia 2011 Dec 31;59(12):1996-2005. Epub 2011 Aug 31.

Department of Neuroscience, Thomas Jefferson University Medical College, 900 Walnut St., Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA.

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http://doi.wiley.com/10.1002/glia.21241
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http://dx.doi.org/10.1002/glia.21241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269541PMC
December 2011

Stem cell transplantation for spinal cord neurodegeneration.

Methods Mol Biol 2011 ;793:479-93

Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/978-1-61779-328-8_31DOI Listing
December 2011

Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.

Proc Natl Acad Sci U S A 2011 Oct 3;108(43):17803-8. Epub 2011 Oct 3.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1103141108
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http://dx.doi.org/10.1073/pnas.1103141108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203804PMC
October 2011

Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury.

J Neurosci Res 2011 Jul 12;89(7):1001-17. Epub 2011 Apr 12.

Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1002/jnr.22624DOI Listing
July 2011

Stem cells and the ALS neurologist.

Amyotroph Lateral Scler 2010 Oct;11(5):417-23

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.3109/17482968.2010.489116DOI Listing
October 2010

Peripheral hyperstimulation alters site of disease onset and course in SOD1 rats.

Neurobiol Dis 2010 Sep 8;39(3):252-64. Epub 2010 Apr 8.

Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.nbd.2010.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910141PMC
September 2010

Advances in stem cell research for Amyotrophic Lateral Sclerosis.

Curr Opin Biotechnol 2009 Oct 12;20(5):545-51. Epub 2009 Oct 12.

Johns Hopkins University, 600 N. Wolfe St., Meyer 6-119, Baltimore, MD 21287, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S095816690900105
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http://dx.doi.org/10.1016/j.copbio.2009.09.003DOI Listing
October 2009

Accurate ALSFRS-R scores can be generated from retrospective review of clinic notes.

Amyotroph Lateral Scler 2009 Aug;10(4):244-7

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1080/17482960802502993DOI Listing
August 2009

Rethinking a drug treatment failure on a traditional ALS target.

Exp Neurol 2009 Apr;216(2):254-7

Department of Neurology, Johns Hopkins University, School of Medicine, 600 N. Wolfe St., Meyer 6-119, Baltimore, MD 21287, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00144886090000
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http://dx.doi.org/10.1016/j.expneurol.2008.12.025DOI Listing
April 2009

Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease.

Nat Neurosci 2008 Nov 19;11(11):1294-301. Epub 2008 Oct 19.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://www.nature.com/articles/nn.2210
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http://dx.doi.org/10.1038/nn.2210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656686PMC
November 2008

Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration.

Exp Neurol 2008 Jun 7;211(2):423-32. Epub 2008 Mar 7.

Department of Neurology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 6-119, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.expneurol.2008.02.020DOI Listing
June 2008

Adult glial precursor proliferation in mutant SOD1G93A mice.

Glia 2008 Jan;56(2):200-8

Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1002/glia.20604DOI Listing
January 2008

Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS.

Brain Res 2007 Dec 22;1185:256-65. Epub 2007 Sep 22.

Department of Neurology, The Johns Hopkins University School of Medicine, 600 N. Wolfe St., Meyer 6-109, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.brainres.2007.09.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265207PMC
December 2007

Impaired SDF1/CXCR4 signaling in glial progenitors derived from SOD1(G93A) mice.

J Neurosci Res 2007 Aug;85(11):2422-32

Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/jnr.21398DOI Listing
August 2007

Mechanisms of Disease: astrocytes in neurodegenerative disease.

Nat Clin Pract Neurol 2006 Dec;2(12):679-89

Department of Neurology, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 6-119, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1038/ncpneuro0355DOI Listing
December 2006

Loss of the astrocyte glutamate transporter GLT1 modifies disease in SOD1(G93A) mice.

Exp Neurol 2006 Sep 6;201(1):120-30. Epub 2006 Jun 6.

Department of Neurology, Johns Hopkins University, 600 N. Wolfe St., Meyer 6-119, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.expneurol.2006.03.028DOI Listing
September 2006

Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection.

Neurobiol Dis 2006 Mar 7;21(3):556-67. Epub 2005 Nov 7.

Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.nbd.2005.08.014DOI Listing
March 2006

Degeneration of respiratory motor neurons in the SOD1 G93A transgenic rat model of ALS.

Neurobiol Dis 2006 Jan 9;21(1):110-8. Epub 2005 Aug 9.

Department of Neurology, Johns Hopkins University. 600 N. Wolfe Street, Meyer 6-119, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.nbd.2005.06.019DOI Listing
January 2006

Glial restricted precursors protect against chronic glutamate neurotoxicity of motor neurons in vitro.

Glia 2005 Apr;50(2):145-59

Department of Neurology and Neuroscience, Johns Hopkins University, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1002/glia.20161DOI Listing
April 2005

Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors.

Mol Cell Neurosci 2004 Nov;27(3):322-31

Department of Neurology and Neuroscience, Johns Hopkins University, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.mcn.2004.07.010DOI Listing
November 2004

Altered expression of the glutamate transporter EAAT2b in neurological disease.

Ann Neurol 2004 Apr;55(4):469-77

Departments of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1002/ana.20003DOI Listing
April 2004

Glutamate transporters: animal models to neurologic disease.

Neurobiol Dis 2004 Apr;15(3):461-73

Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.nbd.2003.12.007DOI Listing
April 2004

Glutamate transporter expression and function in human glial progenitors.

Glia 2004 Jan;45(2):133-43

Department of Neurology and Neuroscience, Johns Hopkins University, Meyer 6-109, 600 N. Wolfe Street, Baltimore, MD 21287-5953, USA.

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http://dx.doi.org/10.1002/glia.10310DOI Listing
January 2004

Amyotrophic lateral sclerosis: pathogenesis, differential diagnoses, and potential interventions.

J Spinal Cord Med 2002 ;25(4):262-73

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1080/10790268.2002.11753626DOI Listing
March 2003

Topiramate protects against motor neuron degeneration in organotypic spinal cord cultures but not in G93A SOD1 transgenic mice.

Neurosci Lett 2003 Feb;338(2):107-10

Johns Hopkins University, Department of Neurology, Meyer 6-109, 600 North Wolfe Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/s0304-3940(02)01386-1DOI Listing
February 2003