Nicholas J Bray

Nicholas J Bray

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Nicholas J Bray

Nicholas J Bray

Publications by authors named "Nicholas J Bray"

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Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics.

Biol Psychiatry 2019 Aug 11;86(4):265-273. Epub 2019 May 11.

Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.04.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664597PMC
August 2019

The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells.

Biol Psychiatry 2019 Jul 30;86(2):120-130. Epub 2019 Mar 30.

Department of Basic & Clinical Neuroscience, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.03.977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614717PMC
July 2019

The genetics of neuropsychiatric disorders.

Brain Neurosci Adv 2019 May 12;2. Epub 2018 Oct 12.

MRC Centre for Neuropsychiatric Genetics and Genomics and Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1177/2398212818799271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551216PMC
May 2019

Transcriptional Changes following Cellular Knockdown of the Schizophrenia Risk Gene Are Enriched for Common Variant Association with the Disorder.

Mol Neuropsychiatry 2019 Apr 25;5(2):109-114. Epub 2019 Mar 25.

MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, United Kingdom.

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http://dx.doi.org/10.1159/000497181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528089PMC
April 2019

5-hydroxymethylcytosine is highly dynamic across human fetal brain development.

BMC Genomics 2017 Sep 18;18(1):738. Epub 2017 Sep 18.

University of Exeter Medical School, RILD Building, Royal Devon and Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.

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http://dx.doi.org/10.1186/s12864-017-4091-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604137PMC
September 2017

Psychosis Risk Candidate ZNF804A Localizes to Synapses and Regulates Neurite Formation and Dendritic Spine Structure.

Biol Psychiatry 2017 07 15;82(1):49-61. Epub 2016 Sep 15.

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London; MRC Centre for Neurodevelopmental Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London; United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2016.08.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482321PMC
July 2017

Knockdown of the schizophrenia susceptibility gene alters gene expression and proliferation of progenitor cells from the developing human neocortex.

J Psychiatry Neurosci 2017 05;42(3):181-188

From the Department of Basic and Clinical Neuroscience, King's College London, London, UK (Hill, Killick, Maruszak, McLaughlin, Williams, Bray); the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK (Navarrete); Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK (Hill); and the MRC Centre for Neuropsychiatric Genetics & Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK (Bray).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403663PMC
May 2017

Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain.

Am J Med Genet B Neuropsychiatr Genet 2016 09 22;171(6):806-14. Epub 2016 Mar 22.

Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.b.32445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988385PMC
September 2016

Translating Genetic Risk Loci Into Molecular Risk Mechanisms for Schizophrenia.

Schizophr Bull 2016 Jan 4;42(1):5-8. Epub 2015 Nov 4.

MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK.

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http://dx.doi.org/10.1093/schbul/sbv156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681566PMC
January 2016

Methylomic trajectories across human fetal brain development.

Genome Res 2015 Mar 3;25(3):338-52. Epub 2015 Feb 3.

Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, United Kingdom; University of Exeter Medical School, University of Exeter, Exeter EX2 5DW, United Kingdom;

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http://dx.doi.org/10.1101/gr.180273.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352878PMC
March 2015

Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells.

Schizophr Res 2014 Mar 18;153(1-3):225-30. Epub 2014 Feb 18.

Department of Neuroscience, Institute of Psychiatry, King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.01.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988999PMC
March 2014

Evidence that schizophrenia risk variation in the ZNF804A gene exerts its effects during fetal brain development.

Am J Psychiatry 2012 Dec;169(12):1301-8

Department of Neuroscience, Institute of Psychiatry, King’s College London, UK.

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http://dx.doi.org/10.1176/appi.ajp.2012.11121845DOI Listing
December 2012

Investigating schizophrenia in a "dish": possibilities, potential and limitations.

World Psychiatry 2012 Oct;11(3):153-5

Department of Neuroscience.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449342PMC
October 2012

Stochastic choice of allelic expression in human neural stem cells.

Stem Cells 2012 Sep;30(9):1938-47

King's College London, Institute of Psychiatry, Centre for the Cellular Basis of Behaviour, Department of Neuroscience, London, United Kingdom.

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http://dx.doi.org/10.1002/stem.1155DOI Listing
September 2012

Knockdown of the psychosis susceptibility gene ZNF804A alters expression of genes involved in cell adhesion.

Hum Mol Genet 2012 Mar 11;21(5):1018-24. Epub 2011 Nov 11.

Department of Neuroscience, Institute of Psychiatry, King’s College London, London, UK.

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http://dx.doi.org/10.1093/hmg/ddr532DOI Listing
March 2012

The neurobiology of schizophrenia: new leads and avenues for treatment.

Curr Opin Neurobiol 2010 Dec 8;20(6):810-5. Epub 2010 Oct 8.

Department of Neuroscience, Institute of Psychiatry, King's College London, UK.

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http://dx.doi.org/10.1016/j.conb.2010.09.008DOI Listing
December 2010

Effects of cis-regulatory variation differ across regions of the adult human brain.

Hum Mol Genet 2010 Nov 9;19(22):4490-6. Epub 2010 Sep 9.

Centre for the Cellular Basis of Behaviour, Department of Neuroscience, The James Black Centre, Institute of Psychiatry,King’s College London, 125 Coldharbour Lane, London, UK.

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http://dx.doi.org/10.1093/hmg/ddq380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298852PMC
November 2010

The effect of age and the H1c MAPT haplotype on MAPT expression in human brain.

Neurobiol Aging 2009 Oct 13;30(10):1652-6. Epub 2008 Feb 13.

Neuropsychiatric Genetics Group, Cardiff University School of Medicine, Cardiff, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.12.017DOI Listing
October 2009

Gene expression in the etiology of schizophrenia.

Authors:
Nicholas J Bray

Schizophr Bull 2008 May 11;34(3):412-8. Epub 2008 Mar 11.

Centre for the Cellular Basis of Behaviour, Department of Neuroscience, Institute of Psychiatry, King's College London, The James Black Centre, London, UK.

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http://dx.doi.org/10.1093/schbul/sbn013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632437PMC
May 2008

Cis- and trans- loci influence expression of the schizophrenia susceptibility gene DTNBP1.

Hum Mol Genet 2008 Apr 8;17(8):1169-74. Epub 2008 Jan 8.

Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddn006DOI Listing
April 2008

Investigating cis-acting regulatory variation using assays of relative allelic expression.

Psychiatr Genet 2006 Aug;16(4):173-7

Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1097/01.ypg.0000218612.35139.84DOI Listing
August 2006

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.

Hum Mol Genet 2005 Jul 25;14(14):1947-54. Epub 2005 May 25.

Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, UK.

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http://academic.oup.com/hmg/article/14/14/1947/608349/Haplot
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http://dx.doi.org/10.1093/hmg/ddi199DOI Listing
July 2005

Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes.

Hum Mol Genet 2004 Nov 22;13(22):2885-92. Epub 2004 Sep 22.

Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff , UK.

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http://academic.oup.com/hmg/article/13/22/2885/610242/Alleli
Publisher Site
http://dx.doi.org/10.1093/hmg/ddh299DOI Listing
November 2004

Cis-acting variation in the expression of a high proportion of genes in human brain.

Hum Genet 2003 Jul 1;113(2):149-53. Epub 2003 May 1.

Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff, CF14 4XN, UK.

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http://dx.doi.org/10.1007/s00439-003-0956-yDOI Listing
July 2003

A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain.

Am J Hum Genet 2003 Jul 11;73(1):152-61. Epub 2003 Jun 11.

Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, CF14 4XN, Wales, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S000292970763901
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180576PMC
http://dx.doi.org/10.1086/376578DOI Listing
July 2003