Publications by authors named "Nicholas Gutowski"

25Publications

Engagement of people with multiple sclerosis to enhance research into the physiological effect of hyperbaric oxygen therapy.

Mult Scler Relat Disord 2020 Aug 29;43:102084. Epub 2020 Apr 29.

Institute of Biomedical and Clinical Sciences, College of Medicine & Healthcare, University of Exeter, Exeter, UK; Royal Devon and Exeter Hospital Foundation Trust, Exeter, UK.

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August 2020

Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14, and TAU3 transcript expression and contribute to cognitive decline.

Geroscience 2019 10 25;41(5):561-573. Epub 2019 Oct 25.

Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, Exeter, Devon, EX2 5DW, UK.

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October 2019

Cathepsin L Induces Proangiogenic Changes in Human Omental Microvascular Endothelial Cells via Activation of the ERK1/2 Pathway.

Curr Cancer Drug Targets 2019 ;19(3):231-242

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon EX1 2LU, United Kingdom.

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July 2020

Cathepsin D non-proteolytically induces proliferation and migration in human omental microvascular endothelial cells via activation of the ERK1/2 and PI3K/AKT pathways.

Biochim Biophys Acta Mol Cell Res 2018 Jan 10;1865(1):25-33. Epub 2017 Oct 10.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon EX1 2LU, UK. Electronic address:

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January 2018

Multifocal necrotising leucoencephalopathy following infection in an immunocompetent patient.

Pract Neurol 2018 Apr 28;18(2):156-158. Epub 2017 Sep 28.

Department of Neurology, Royal Devon and Exeter Hospital, Exeter, UK.

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April 2018

The Potential Role of the Proteases Cathepsin D and Cathepsin L in the Progression and Metastasis of Epithelial Ovarian Cancer.

Biomolecules 2015 Nov 20;5(4):3260-79. Epub 2015 Nov 20.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon EX1 2LU, UK.

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November 2015

Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endothelium.

J Exp Clin Cancer Res 2015 Sep 25;34:105. Epub 2015 Sep 25.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, St. Luke's campus, Exeter, EX1 2LU, UK.

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September 2015

CD20+inflammatory T-cells are present in blood and brain of multiple sclerosis patients and can be selectively targeted for apoptotic elimination.

Mult Scler Relat Disord 2014 Sep 12;3(5):650-8. Epub 2014 Jun 12.

University of Exeter Medical School & Neurology Department, Royal Devon and Exeter Hospital, University of Exeter, Devon, UK. Electronic address:

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September 2014

The difficulty in diagnosing X linked adrenoleucodystrophy and the importance of identifying cerebral involvement.

BMJ Case Rep 2015 May 12;2015. Epub 2015 May 12.

Department of Neurology, Royal Devon and Exeter Hospital, Exeter, Devon, UK.

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May 2015

Cavernous sinus syndrome with pachymeningitis.

Pract Neurol 2011 Oct;11(5):308-9

Neurology Department, The Royal Devon and Exeter Hospital, Exeter, Devon, UK.

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October 2011

An improved and reliable method for isolation of microvascular endothelial cells from human omentum.

Microcirculation 2011 Nov;18(8):635-45

Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, St Luke's Campus, Exeter, Devon, UK.

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November 2011

Increased blood vessel density and endothelial cell proliferation in multiple sclerosis cerebral white matter.

Neurosci Lett 2010 Feb 29;470(1):65-70. Epub 2009 Dec 29.

Peninsula Medical School, University of Exeter, St Luke's Campus, Magdalen Road, Exeter, EX1 2LU, United Kingdom.

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February 2010

The role of the ventrolateral frontal cortex in inhibitory oculomotor control.

Brain 2007 Jun 23;130(Pt 6):1525-37. Epub 2007 Apr 23.

Exeter Centre for Cognitive Neuroscience, School of Psychology, University of Exeter, Washington Singer Laboratories, Prince of Wales Road, Exeter EX4 4QG.

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June 2007

Tenascin C induces a quiescent phenotype in cultured adult human astrocytes.

Glia 2005 Oct;52(1):53-8

Institute of Biomedical and Clinical Sciences, Peninsula Medical School (Exeter), Department of Neurology, Royal Devon and Exeter Hospital, Exeter, United Kingdom.

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October 2005