Nicholas F Lahens

Nicholas F Lahens

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Nicholas F Lahens

Nicholas F Lahens

Publications by authors named "Nicholas F Lahens"

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17Publications

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G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment.

PLoS Biol 2019 04 30;17(4):e3000228. Epub 2019 Apr 30.

Penn Chronobiology, Howard Hughes Medical Institute, Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://dx.plos.org/10.1371/journal.pbio.3000228
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http://dx.doi.org/10.1371/journal.pbio.3000228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490878PMC
April 2019

Cyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs.

Circulation 2018 11;138(21):2367-2378

Department of Systems Pharmacology and Translational Therapeutics and the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, Philadelphia, PA (E.R., S.Y.T., D.M., S.D.R., H.M., X.L., N.F.L., A.M.W., G.A.F.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.033540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291350PMC
November 2018

A Pilot Characterization of the Human Chronobiome.

Sci Rep 2017 12 7;7(1):17141. Epub 2017 Dec 7.

Department of Systems Pharmacology and Translational Therapeutics, at the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41598-017-17362-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719427PMC
December 2017

A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression.

BMC Genomics 2017 08 10;18(1):602. Epub 2017 Aug 10.

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1186/s12864-017-4011-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553782PMC
August 2017

The Nephila clavipes genome highlights the diversity of spider silk genes and their complex expression.

Nat Genet 2017 Jun 1;49(6):895-903. Epub 2017 May 1.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3852DOI Listing
June 2017

A new view of transcriptome complexity and regulation through the lens of local splicing variations.

Elife 2016 Feb 1;5:e11752. Epub 2016 Feb 1.

Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.

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http://dx.doi.org/10.7554/eLife.11752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801060PMC
February 2016

Ribosome profiling reveals an important role for translational control in circadian gene expression.

Genome Res 2015 Dec 3;25(12):1836-47. Epub 2015 Sep 3.

Department of Neuroscience, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA; Howard Hughes Medical Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1101/gr.191296.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665005PMC
December 2015

Benchmark analysis of algorithms for determining and quantifying full-length mRNA splice forms from RNA-seq data.

Bioinformatics 2015 Dec 3;31(24):3938-45. Epub 2015 Sep 3.

University of Pennsylvania, Institute for Translational Medicine and Therapeutics, Philadelphia, PA 19104, Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/bioinformatics/btv488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673975PMC
December 2015

A circadian gene expression atlas in mammals: implications for biology and medicine.

Proc Natl Acad Sci U S A 2014 Nov 27;111(45):16219-24. Epub 2014 Oct 27.

Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; and

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http://dx.doi.org/10.1073/pnas.1408886111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234565PMC
November 2014

CircaDB: a database of mammalian circadian gene expression profiles.

Nucleic Acids Res 2013 Jan 24;41(Database issue):D1009-13. Epub 2012 Nov 24.

The Institute for Translational Medicine and Therapeutics, University of Pennsylvania, 3400 Civic Center Boulevard, Building 421, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/nar/gks1161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531170PMC
January 2013