Nicholas Duesbery

Nicholas Duesbery

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Nicholas Duesbery

Nicholas Duesbery

Publications by authors named "Nicholas Duesbery"

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36Publications

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Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts.

Int J Oncol 2015 Jul 6;47(1):71-80. Epub 2015 May 6.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.3892/ijo.2015.2989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485647PMC
July 2015

Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.

Am J Cancer Res 2015 15;5(4):1507-18. Epub 2015 Mar 15.

Center for Translational Medicine, Van Andel Research Institute Grand Rapids, Michigan, USA ; Current address: Medimmune, One MedImmune Way Gaithersburg, MD, 20878, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473327PMC
June 2015

A human/murine chimeric fab antibody neutralizes anthrax lethal toxin in vitro.

Clin Dev Immunol 2013 5;2013:475809. Epub 2013 Jun 5.

Department of Pathology, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029, China.

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http://www.hindawi.com/journals/jir/2013/475809/
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http://dx.doi.org/10.1155/2013/475809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687597PMC
December 2013

Identification of VEGF-independent cytokines in proliferative diabetic retinopathy vitreous.

Invest Ophthalmol Vis Sci 2013 Oct 3;54(10):6472-80. Epub 2013 Oct 3.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan.

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http://dx.doi.org/10.1167/iovs.13-12518DOI Listing
October 2013

Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma.

Mol Cancer Ther 2013 Sep 26;12(9):1701-14. Epub 2013 Jun 26.

Corresponding Author: Nicholas S. Duesbery, Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, 333 Bostwick Ave., NE, Grand Rapids, MI 49503.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769440PMC
September 2013

MEK genomics in development and disease.

Brief Funct Genomics 2012 Jul 29;11(4):300-10. Epub 2012 Jun 29.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, 333 Bostwick Avenue NE, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1093/bfgp/els022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398258PMC
July 2012

Persistent inhibition of oxygen-induced retinal neovascularization by anthrax lethal toxin.

Invest Ophthalmol Vis Sci 2011 Nov 21;52(12):8979-92. Epub 2011 Nov 21.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://dx.doi.org/10.1167/iovs.11-7651DOI Listing
November 2011

MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.

PLoS One 2011 Feb 18;6(2):e17165. Epub 2011 Feb 18.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017165PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041822PMC
February 2011

Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.

Toxins (Basel) 2010 05 11;2(5):1038-53. Epub 2010 May 11.

Laboratory of Cancer and Developmental Cell Biology, The Van Andel Research Institute, 333 Bostwick NE Grand Rapids, MI, USA.

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http://dx.doi.org/10.3390/toxins2051038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153234PMC
May 2010

Perturbation of mouse retinal vascular morphogenesis by anthrax lethal toxin.

PLoS One 2009 Sep 14;4(9):e6956. Epub 2009 Sep 14.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006956PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737623PMC
September 2009

Pathophysiology of anthrax.

Front Biosci (Landmark Ed) 2009 Jan 1;14:4516-24. Epub 2009 Jan 1.

Scott and White Memorial Hospital, Temple, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109055PMC
http://dx.doi.org/10.2741/3544DOI Listing
January 2009

Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage.

Microb Pathog 2008 Jun 23;44(6):467-72. Epub 2007 Dec 23.

Cancer Research Institute, Scott & White Memorial Hospital,Temple, TX 76502, USA.

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http://dx.doi.org/10.1016/j.micpath.2007.12.001DOI Listing
June 2008

Biological and biochemical characterization of anthrax lethal factor, a proteolytic inhibitor of MEK signaling pathways.

Methods Enzymol 2008 ;438:355-65

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, USA.

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http://dx.doi.org/10.1016/S0076-6879(07)38025-7DOI Listing
June 2008

Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma.

Mol Cancer Ther 2008 Mar 4;7(3):648-58. Epub 2008 Mar 4.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2229DOI Listing
March 2008

A tribute to George F. Vande Woude, a man of character: 2006 Scientific Symposium Winning the War against Cancer: from Genomics to Bedside and Back.

Cancer Res 2007 Mar 8;67(6):2394-5. Epub 2007 Mar 8.

Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-06-4304DOI Listing
March 2007

Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice.

Clin Cancer Res 2006 Dec;12(24):7437-43

Cancer Research Institute, Scott & White Memorial Hospital, Temple, Texas 76502, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2019DOI Listing
December 2006

Xenopus tropicalis oocytes: more than just a beautiful genome.

Methods Mol Biol 2006 ;322:43-53

Laboratoire de Biologie du Développement, UPRES EA3, Université des sciences et technologies de Lille, France.

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http://dx.doi.org/10.1007/978-1-59745-000-3_4DOI Listing
June 2006

Involvement of domain II in toxicity of anthrax lethal factor.

J Biol Chem 2004 Dec 1;279(50):52473-8. Epub 2004 Oct 1.

Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://dx.doi.org/10.1074/jbc.M409105200DOI Listing
December 2004

Novel protein targeted therapy of metastatic melanoma.

Curr Pharm Des 2003 ;9(25):2060-6

Wake Forest University School of Medicine, Wisnton-Salem, NC 27157-102, USA.

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http://dx.doi.org/10.2174/1381612033454162DOI Listing
February 2004

Anthrax lethal factor proteolysis and inactivation of MAPK kinase.

J Biol Chem 2003 Mar 9;278(11):9402-6. Epub 2003 Jan 9.

Laboratory of Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://dx.doi.org/10.1074/jbc.M211262200DOI Listing
March 2003

Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha.

J Biol Chem 2003 Feb 17;278(9):7413-21. Epub 2002 Dec 17.

Department of Immunology, Scripps Research Institute, La Jolla, California 92037, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M209279200
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http://dx.doi.org/10.1074/jbc.M209279200DOI Listing
February 2003

Characterization of MPF and MAPK activities during meiotic maturation of Xenopus tropicalis oocytes.

Dev Biol 2002 May;245(2):348-61

Van Andel Research Institute, Laboratory of Developmental Cell Biology, Special Program in Analytical, Cellular, and Molecular Microscopy, 333 Bostwick NE, Grand Rapids, Michigan 49503, USA.

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http://dx.doi.org/10.1006/dbio.2002.0647DOI Listing
May 2002

Developmental biology: an arresting activity.

Nature 2002 Apr;416(6883):804-5

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http://dx.doi.org/10.1038/416804aDOI Listing
April 2002