Publications by authors named "Nicholas D Huntington"

99Publications

Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance.

Cell Rep 2020 Oct;33(3):108285

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, 3010, Australia; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, 3800, Australia; oNKo-Innate Pty Ltd., 27 Norwood Cres, Moonee Ponds, Victoria, 3039, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.108285DOI Listing
October 2020

The Antitumor Effect of Heparin is not Mediated by Direct NK Cell Activation.

J Clin Med 2020 Aug 18;9(8). Epub 2020 Aug 18.

The University of Queensland Diamantina Institute, University of Queensland, Woolloongabba, QLD 4102, Australia.

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http://dx.doi.org/10.3390/jcm9082666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463539PMC
August 2020

The cancer-natural killer cell immunity cycle.

Nat Rev Cancer 2020 08 24;20(8):437-454. Epub 2020 Jun 24.

Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41568-020-0272-zDOI Listing
August 2020

Harnessing Natural Killer Immunity in Metastatic SCLC.

J Thorac Oncol 2020 Sep 26;15(9):1507-1521. Epub 2020 May 26.

ACRF Cancer Biology and Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2020.05.008DOI Listing
September 2020

You Have Got a Fast CAR: Chimeric Antigen Receptor NK Cells in Cancer Therapy.

Cancers (Basel) 2020 Mar 17;12(3). Epub 2020 Mar 17.

Biomedicine Discovery Institute and the Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.3390/cancers12030706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140022PMC
March 2020

Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases.

Front Immunol 2020 21;11:282. Epub 2020 Feb 21.

The Ministry of Education Key Laboratory, Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.3389/fimmu.2020.00282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047319PMC
February 2020

Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a.

Eur J Immunol 2020 07 4;50(7):959-971. Epub 2020 Mar 4.

Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/eji.201948371DOI Listing
July 2020

NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS.

Front Immunol 2020 31;11:75. Epub 2020 Jan 31.

Division of Molecular Immunology, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2020.00075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005222PMC
January 2020

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity.

Sci Signal 2019 08 27;12(596). Epub 2019 Aug 27.

Division of Molecular Immunology, The Walter and Eliza Hall Institute of Medical Research and Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1126/scisignal.aat7527DOI Listing
August 2019

Impact of Tumor and Immunological Heterogeneity on the Anti-Cancer Immune Response.

Cancers (Basel) 2019 Aug 21;11(9). Epub 2019 Aug 21.

Department of Clinical Pathology, Victorian Comprehensive Cancer Centre, The University of Melbourne, Melbourne, VIC 3000, Australia.

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https://www.mdpi.com/2072-6694/11/9/1217
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http://dx.doi.org/10.3390/cancers11091217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770225PMC
August 2019

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection.

Cell Rep 2019 08;28(7):1758-1772.e4

Division of Immunology, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711398PMC
August 2019

Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β.

Front Immunol 2019 1;10:904. Epub 2019 May 1.

Division of Immunology/Molecular Immunology, Department of Medical Biology, The Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2019.00904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506781PMC
June 2020

A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma Patients.

Cancer Immunol Res 2019 07 14;7(7):1162-1174. Epub 2019 May 14.

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0500DOI Listing
July 2019

Quantifying NK cell growth and survival changes in response to cytokines and regulatory checkpoint blockade helps identify optimal culture and expansion conditions.

J Leukoc Biol 2019 06 12;105(6):1341-1354. Epub 2019 May 12.

Division of Molecular Immunology, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

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http://dx.doi.org/10.1002/JLB.MA0718-296RDOI Listing
June 2019

The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy.

Trends Immunol 2019 02 10;40(2):142-158. Epub 2019 Jan 10.

Molecular Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria 3010, Australia; Biomedicine Discovery Institute and the Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.it.2018.12.003DOI Listing
February 2019

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells.

Mol Immunol 2019 11 23;115:56-63. Epub 2018 Aug 23.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Victoria, 3010 Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2018.08.017DOI Listing
November 2019

Immune homeostasis in health and disease.

Immunol Cell Biol 2018 05;96(5):451-452

The Walter and Eliza Hall Institute, 1G Royal Parade, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1111/imcb.12043DOI Listing
May 2018

Molecular insight into targeting the NK cell immune response to cancer.

Immunol Cell Biol 2018 05 17;96(5):477-484. Epub 2018 Apr 17.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1111/imcb.12045DOI Listing
May 2018

A new checkpoint for Natural Killer cell activation.

Immunol Cell Biol 2018 01 15;96(1):5-7. Epub 2017 Dec 15.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic. 3052, Australia.

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http://doi.wiley.com/10.1111/imcb.1027
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http://dx.doi.org/10.1111/imcb.1027DOI Listing
January 2018

Identification of Novel Human NK Cell Progenitor Subsets.

Int J Mol Sci 2017 Dec 15;18(12). Epub 2017 Dec 15.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.3390/ijms18122716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751317PMC
December 2017

The life and death of immune cell types: the role of BCL-2 anti-apoptotic molecules.

Immunol Cell Biol 2017 11 6;95(10):870-877. Epub 2017 Sep 6.

Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/icb.2017.72DOI Listing
November 2017

Natural-Killer-like B Cells Display the Phenotypic and Functional Characteristics of Conventional B Cells.

Immunity 2017 08;47(2):199-200

Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, Marseille, France; Service d'Immunologie, Hôpital de la Timone, Assistance Publique - Hôpitaux de Marseille, Marseille, France.

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http://dx.doi.org/10.1016/j.immuni.2017.07.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705200PMC
August 2017

Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis.

Cancer Res 2017 09 26;77(17):4684-4696. Epub 2017 Jun 26.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0393DOI Listing
September 2017

Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis.

Oncoimmunology 2017 7;6(2):e1267892. Epub 2017 Feb 7.

Immunology of Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia; School of Medicine, The University of Queensland, Herston, Queensland, Australia.

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https://www.tandfonline.com/doi/full/10.1080/2162402X.2016.1
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http://dx.doi.org/10.1080/2162402X.2016.1267892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353935PMC
February 2017

Regulation of Murine Natural Killer Cell Development.

Front Immunol 2017 15;8:130. Epub 2017 Feb 15.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2017.00130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309223PMC
February 2017

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.

Blood 2017 02 7;129(5):630-642. Epub 2016 Dec 7.

Bone Marrow Transplantation Laboratory, Immunology Department, Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1182/blood-2016-08-734020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290987PMC
February 2017

IL-15 signaling in NK cell cancer immunotherapy.

Curr Opin Immunol 2017 Feb 11;44:1-6. Epub 2016 Nov 11.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2016.10.004DOI Listing
February 2017

Type 1 Innate Lymphoid Cell Biology: Lessons Learnt from Natural Killer Cells.

Front Immunol 2016 12;7:426. Epub 2016 Oct 12.

Molecular Immunology Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2016.00426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059362PMC
October 2016

Deciphering the Innate Lymphoid Cell Transcriptional Program.

Cell Rep 2016 10;17(2):436-447

The Walter and Eliza Hall Institute of Medical Research and Department of Medical Biology, University of Melbourne, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.025DOI Listing
October 2016

Targeting natural killer cells in cancer immunotherapy.

Nat Immunol 2016 08;17(9):1025-36

Immunology of Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.

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http://dx.doi.org/10.1038/ni.3518DOI Listing
August 2016

Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells.

J Immunol 2016 09 29;197(5):2000-8. Epub 2016 Jul 29.

Immunology Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia; Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia

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http://dx.doi.org/10.4049/jimmunol.1600181DOI Listing
September 2016

Transforming growth factor-β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells.

Sci Signal 2016 05 3;9(426):ra46. Epub 2016 May 3.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia. Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1126/scisignal.aaf2176DOI Listing
May 2016

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway.

Sci Signal 2016 Feb 16;9(415):ra19. Epub 2016 Feb 16.

Centre International de Recherche en Infectiologie (CIRI), 69007 Lyon, France. INSERM U1111, 69007 Lyon, France. Ecole Normale Supérieure de Lyon, 69007 Lyon, France. Université Lyon 1, 69007 Lyon, France. CNRS, UMR5308, 69007 Lyon, France.

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http://dx.doi.org/10.1126/scisignal.aad1884DOI Listing
February 2016

Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells.

Curr Opin Immunol 2016 Feb 29;38:86-93. Epub 2015 Dec 29.

The Walter and Eliza Hall Institute of Medical Research, and Department of Medical Biology, University of Melbourne, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2015.11.008DOI Listing
February 2016

DNAM-1: would the real natural killer cell please stand up!

Oncotarget 2015 Oct;6(30):28537-8

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.18632/oncotarget.5952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745675PMC
October 2015

Development, Homeostasis, and Heterogeneity of NK Cells and ILC1.

Curr Top Microbiol Immunol 2016 ;395:37-61

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1007/82_2015_474DOI Listing
June 2016

DNAM-1 expression marks an alternative program of NK cell maturation.

Cell Rep 2015 Apr 26;11(1):85-97. Epub 2015 Mar 26.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia; School of Medicine, University of Queensland, Herston, QLD 4006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.03.006DOI Listing
April 2015

A novel mouse model for stable engraftment of a human immune system and human hepatocytes.

PLoS One 2015 17;10(3):e0119820. Epub 2015 Mar 17.

Innate Immunity Unit, Department of Immunology, Institut Pasteur, Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U668, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119820PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364106PMC
March 2016

Peripheral natural killer cell maturation depends on the transcription factor Aiolos.

EMBO J 2014 Nov 15;33(22):2721-34. Epub 2014 Oct 15.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia

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http://dx.doi.org/10.15252/embj.201487900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282578PMC
November 2014

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells.

Nat Commun 2014 Aug 14;5:4539. Epub 2014 Aug 14.

1] The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia [2] Department of Medical Biology, University of Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1038/ncomms5539DOI Listing
August 2014

Nfil3 is required for the development of all innate lymphoid cell subsets.

J Exp Med 2014 Aug 4;211(9):1733-40. Epub 2014 Aug 4.

Division of Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, Victoria 3010, Australia

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http://dx.doi.org/10.1084/jem.20140145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144736PMC
August 2014

Lymphoid tissue and plasmacytoid dendritic cells and macrophages do not share a common macrophage-dendritic cell-restricted progenitor.

Immunity 2014 Jul;41(1):104-15

The Walter and Eliza Hall Institute, Parkville, VIC 3050, Australia; Department of Medical Biology, The University of Melbourne, VIC 3010, Australia; Burnet Institute, Melbourne, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.05.020DOI Listing
July 2014

CD19 differentially regulates BCR signalling through the recruitment of PI3K.

Autoimmunity 2014 Nov 23;47(7):430-7. Epub 2014 Jun 23.

The Walter and Eliza Hall Institute of Medical Research , Department of Medical Biology, The University of Melbourne , Australia .

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http://dx.doi.org/10.3109/08916934.2014.921810DOI Listing
November 2014

NK cell recognition of unconventional ligands.

Immunol Cell Biol 2014 Mar;92(3):208-9

Department of Molecular Immunology, The Walter & Eliza Hall Institute, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/icb.2014.6DOI Listing
March 2014

Differential requirement for Nfil3 during NK cell development.

J Immunol 2014 Mar 14;192(6):2667-76. Epub 2014 Feb 14.

Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia;

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http://dx.doi.org/10.4049/jimmunol.1302605DOI Listing
March 2014

The unconventional expression of IL-15 and its role in NK cell homeostasis.

Immunol Cell Biol 2014 Mar 4;92(3):210-3. Epub 2014 Feb 4.

The Walter and Eliza Hall Institute, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/icb.2014.1DOI Listing
March 2014

Regulation of murine natural killer cell commitment.

Front Immunol 2013 30;4:14. Epub 2013 Jan 30.

Molecular Immunology Division, Walter and Eliza Hall Institute of Medical Research Parkville, VIC, Australia ; Department of Medical Biology, The University of Melbourne Parkville, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2013.00014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558707PMC
February 2013

Phosphatidylinositol-3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase.

Immunol Cell Biol 2012 Oct 10;90(9):903-11. Epub 2012 Jul 10.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

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http://dx.doi.org/10.1038/icb.2012.31DOI Listing
October 2012

Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.

J Immunol 2012 May 9;188(10):5094-105. Epub 2012 Apr 9.

Department of Microbiology and Immunology, I3 Research Group, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.

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http://dx.doi.org/10.4049/jimmunol.1103395DOI Listing
May 2012

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Proc Natl Acad Sci U S A 2011 Aug 25;108(32):13224-9. Epub 2011 Jul 25.

Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam, Center for Immunology Amsterdam, 1105AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1073/pnas.1101398108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156191PMC
August 2011

Autonomous and extrinsic regulation of thymopoiesis in human immune system (HIS) mice.

Eur J Immunol 2011 Oct 30;41(10):2883-93. Epub 2011 Aug 30.

Innate Immunity Unit, Immunology Department, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1002/eji.201141586DOI Listing
October 2011

A role for Blimp1 in the transcriptional network controlling natural killer cell maturation.

Blood 2011 Feb 3;117(6):1869-79. Epub 2010 Dec 3.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1182/blood-2010-08-303123DOI Listing
February 2011

Cutting Edge: a thymocyte-thymic epithelial cell cross-talk dynamically regulates intrathymic IL-7 expression in vivo.

J Immunol 2010 Jun 3;184(11):5949-53. Epub 2010 May 3.

Cytokines and Lymphoid Development Unit, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.4049/jimmunol.1000601DOI Listing
June 2010

CpG inhibits pro-B cell expansion through a cathepsin B-dependent mechanism.

J Immunol 2010 May 16;184(10):5678-85. Epub 2010 Apr 16.

Unité du Développement des Lymphocytes, Département d'Immunologie, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.4049/jimmunol.0903854DOI Listing
May 2010

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7.

Int Immunol 2009 Jun 19;21(6):715-25. Epub 2009 May 19.

Cytokines and Lymphoid Development Unit, Institut Pasteur, 25 rue du Docteur Roux, Paris, France.

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http://dx.doi.org/10.1093/intimm/dxp043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980998PMC
June 2009

Characterization of the thymic IL-7 niche in vivo.

Proc Natl Acad Sci U S A 2009 Feb 21;106(5):1512-7. Epub 2009 Jan 21.

Cytokines and Lymphoid Development Unit, Lymphocyte Development Unit, Plate-Forme Technologique Centre d'Ingénierie Génétique Murine, and Laboratory of Lymphoid Tissue Development, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1073/pnas.0809559106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635771PMC
February 2009

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo.

J Exp Med 2009 Jan 22;206(1):25-34. Epub 2008 Dec 22.

Immunology Department, 2 Institut National de la Santé et de la Recherche Médicale U668, 3 INSERM U883, Unité de Régulation Immunitaire et Vaccinologie, Institut Pasteur, Paris 75724, France.

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http://dx.doi.org/10.1084/jem.20082013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626663PMC
January 2009

Developmental pathways that generate natural-killer-cell diversity in mice and humans.

Nat Rev Immunol 2007 Sep;7(9):703-14

Cytokines and Lymphoid Development Unit and Inserm Unit 668, Institut Pasteur, 25 Rue du Docteur Roux, 75724 Paris, Cedex 15, France.

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http://dx.doi.org/10.1038/nri2154DOI Listing
September 2007

10th Meeting of the Society for Natural Immunity, Cambridge, UK, 11-14 April 2007.

Immunol Cell Biol 2007 Oct 7;85(7):508-10. Epub 2007 Aug 7.

Cytokines and Lymphoid Development Unit, Institut Pasteur, Inserm U668, Paris, France.

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http://dx.doi.org/10.1038/sj.icb.7100110DOI Listing
October 2007

NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation.

J Immunol 2007 Apr;178(8):4764-70

Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.4049/jimmunol.178.8.4764DOI Listing
April 2007

Different kinetics of blimp-1 induction in B cell subsets revealed by reporter gene.

J Immunol 2007 Apr;178(7):4104-11

Immunology Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria, Australia.

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http://dx.doi.org/10.4049/jimmunol.178.7.4104DOI Listing
April 2007

Functional subsets of mouse natural killer cells.

Immunol Rev 2006 Dec;214:47-55

Cancer Immunology Program, Sir Donald and Lady Trescowick Laboratories, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/j.1600-065X.2006.00454.xDOI Listing
December 2006

CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers.

Nat Immunol 2006 Feb 25;7(2):190-8. Epub 2005 Dec 25.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia.

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http://www.nature.com/articles/ni1292
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http://dx.doi.org/10.1038/ni1292DOI Listing
February 2006

A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells.

J Exp Med 2005 May;201(9):1421-33

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1084/jem.20042294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213181PMC
May 2005

Lyn tyrosine kinase: accentuating the positive and the negative.

Immunity 2005 Jan;22(1):9-18

The Walter and Eliza Hall Institute of Medical Research, Melbourne 3050, Australia.

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http://dx.doi.org/10.1016/j.immuni.2004.12.004DOI Listing
January 2005

CD45: direct and indirect government of immune regulation.

Immunol Lett 2004 Jul;94(3):167-74

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic. 3050, Australia.

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http://dx.doi.org/10.1016/j.imlet.2004.05.011DOI Listing
July 2004