Nicholas Clarke

Nicholas Clarke

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Nicholas Clarke

Nicholas Clarke

Publications by authors named "Nicholas Clarke"

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99Publications

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FerriTag is a new genetically-encoded inducible tag for correlative light-electron microscopy.

Nat Commun 2018 07 4;9(1):2604. Epub 2018 Jul 4.

Centre for Mechanochemical Cell Biology, Warwick Medical School, Gibbet Hill Road, Coventry, CV4 7AL, UK.

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July 2018

Robotic-assisted microvascular surgery: skill acquisition in a rat model.

J Robot Surg 2018 Jun 10;12(2):331-336. Epub 2017 Aug 10.

Division of Cardiothoracic Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-8879, USA.

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June 2018

Liver resection for non-colorectal non-neuroendocrine metastases.

ANZ J Surg 2018 Apr 3;88(4):E313-E317. Epub 2016 Aug 3.

University of Adelaide Discipline of Surgery, The Queen Elizabeth Hospital, Woodville, South Australia, Australia.

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April 2018

Influence of metformin and insulin on myocardial substrate oxidation under conditions encountered during cardiac surgery.

Surgery 2018 02 11;163(2):436-443. Epub 2017 Dec 11.

Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX.

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February 2018

The potential role of variations in juvenile hip geometry on the development of Legg-Calvé-Perthes disease: a biomechanical investigation.

Comput Methods Biomech Biomed Engin 2018 Feb 8;21(2):194-200. Epub 2018 Feb 8.

a School of Engineering and Computer Science , University of Hull , Hull , United Kingdom of Great Britain and Northern Ireland.

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February 2018

Correlating light microscopy with serial block face scanning electron microscopy to study mitotic spindle architecture.

Methods Cell Biol 2018 ;145:29-43

Centre for Mechanochemical Cell Biology, Warwick Medical School, Coventry, United Kingdom. Electronic address:

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January 2018

New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision.

J Cell Biol 2017 12 27;216(12):4351-4365. Epub 2017 Sep 27.

Centre for Mechanochemical Cell Biology, Warwick Medical School, University of Warwick, Coventry, England, UK

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December 2017

Hypertrophic obstructive cardiomyopathy: review of surgical treatment.

Asian Cardiovasc Thorac Ann 2017 Nov 13;25(9):594-607. Epub 2017 Sep 13.

1 Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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November 2017

Mixed Total Anomalous Pulmonary Venous Return With Ascending and Descending Vertical Veins.

World J Pediatr Congenit Heart Surg 2017 09;8(5):633-634

4 Division of Pediatric Cardiothoracic Surgery, Rady Children's Hospital, University of California, San Diego, CA, USA.

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September 2017

Factors influencing trainee doctor emigration in a high income country: a mixed methods study.

Hum Resour Health 2017 09 25;15(1):66. Epub 2017 Sep 25.

Department of Epidemiology and Public Health Medicine, RCSI, Beaux Lane House, Mercer Street, Dublin 2, Ireland.

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September 2017

'You do not cross them': Hierarchy and emotion in doctors' narratives of power relations in specialist training.

Soc Sci Med 2017 08 27;186:70-77. Epub 2017 May 27.

Royal College of Surgeons in Ireland, Department of Epidemiology and Public Health Medicine, Ireland. Electronic address:

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August 2017

Coxiella burnetti-associated thoracic endovascular stent graft infection.

J Card Surg 2017 Aug 26;32(8):506-507. Epub 2017 Jun 26.

Division of Pediatric Cardiothoracic Surgery, Rady Children's Hospital, University of California, San Diego, California.

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August 2017

Does Late Hip Dysplasia Occur After Normal Ultrasound Screening in Breech Babies?

J Pediatr Orthop 2017 Aug 11. Epub 2017 Aug 11.

*Child Health †NIHR Research Design Service South Central, University Hospital Southampton NHS Foundation Trust ‡Department of Paediatric Orthopaedics, University of Southampton, Southampton, UK.

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August 2017

Persistent Left Superior Vena Cava: Incidence and Management in Patients Undergoing Repair of Partial Anomalous Pulmonary Venous Connection.

World J Pediatr Congenit Heart Surg 2017 07;8(4):440-444

3 Division of Pediatric Cardiothoracic Surgery, Nicklaus Children's Hospital, Miami, FL, USA.

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July 2017

Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment.

J Cell Biol 2017 06 11;216(6):1623-1639. Epub 2017 May 11.

Centre for Mechanochemical Cell Biology, Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, England, UK

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June 2017

Ethnicity as a confounding factor for the incidence of developmental dysplasia of the hip in the UK.

Arch Dis Child 2017 May 13;102(5):477. Epub 2017 Mar 13.

Department of Paediatric Orthopaedics, Southampton Children's Hospital, University Hospital Southampton, Southampton, Hampshire, UK.

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May 2017

Transplantation in a patient on extracorporeal membrane oxygenation with infective endocarditis, pericarditis and heparin-induced thrombocytopenia.

Interact Cardiovasc Thorac Surg 2017 03;24(3):462-463

Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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March 2017

Vitamin D Deficiency in Slipped Upper Femoral Epiphysis: Time to Physeal Fusion.

J Pediatr Orthop 2016 Apr-May;36(3):247-52

*Child Health §NIHR Research Design Service South Central, Southampton General Hospital †Faculty of Medicine ∥Southampton General Hospital, University of Southampton, Southampton ‡Bristol Children's Hospital/Bristol Royal Infirmary, Bristol, UK.

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November 2016

Scimitar syndrome with atrial fibrillation: Repair in an adult.

J Thorac Cardiovasc Surg 2016 11 18;152(5):e105-e107. Epub 2016 Jun 18.

Division of Pediatric Cardiothoracic Surgery, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, Tex.

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November 2016

Closed Reduction for Developmental Dysplasia of the Hip: Early-term Results From a Prospective, Multicenter Cohort.

J Pediatr Orthop 2016 Nov 11. Epub 2016 Nov 11.

*Division of Orthopaedics, Children's Hospital of Philadelphia, Philadelphia, PA †University Hospital Southampton NHS Foundation Trust, University of Southampton, Southampton, UK ‡Arnold Palmer Medical Center, Orlando, FL §Hospital for Sick Children, Toronto, ON ¶British Columbia Children's Hospital #Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada ∥Boston Children's Hospital, Boston, MA **Rady Children's Hospital, San Diego, CA ††Women's and Children's Hospital, North Adelaide ‡‡Centre for Orthopaedic and Trauma Research, University of Adelaide, Adelaide, SA, Australia.

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November 2016

Aortoesophageal Fistula in a Child With Undiagnosed Vascular Ring: Life-Threatening or Lethal?

Ann Thorac Surg 2016 Oct;102(4):e325-7

Division of Pediatric Cardiothoracic Surgery, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, Texas.

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October 2016

Skeletal immaturity, rostral sparing, and disparate hip morphologies as biomechanical causes for Legg-Calvé-Perthes' disease.

Clin Anat 2016 Sep 31;29(6):759-72. Epub 2016 Mar 31.

Medical and Biological Engineering Research Group, School of Engineering, University of Hull, Hull, East Yorkshire, HU6 7RX, United Kingdom.

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September 2016

Acetabuloplasties at Open Reduction Prevent Acetabular Dysplasia in Intentionally Delayed Developmental Dysplasia of the Hip: A Case-control Study.

Clin Orthop Relat Res 2016 May;474(5):1180-8

University of Southampton and University Hospital Southampton Foundation Trust, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.

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May 2016

Transient neonatal radial nerve palsy. A case series and review of the literature.

J Hand Ther 2015 Apr-Jun;28(2):212-5; quiz 216. Epub 2014 Oct 29.

University Hospital of Southampton NHS Foundation Trust, Tremona Road, Southampton SO16 6YD, UK; Faculty of Medicine, University of Southampton, Tremona Road, Southampton SO16 6HW, UK.

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February 2016

Adverse Outcomes in Infantile Bilateral Developmental Dysplasia of the Hip.

J Pediatr Orthop 2015 Jul-Aug;35(5):490-5

*Southampton General Hospital †Department of Child Health, University Hospital Southampton NHS Foundation Trust ‡University of Southampton and Child Health, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UK.

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December 2015

Reliability of a New Radiographic Classification for Developmental Dysplasia of the Hip.

J Pediatr Orthop 2015 Jul-Aug;35(5):478-84

*Hospital for Sick Children, Toronto, ON †British Columbia Children's Hospital, Vancouver, BC, Canada ‡Children's Hospital of Philadelphia, Philadelphia, PA ∥Scripps Mercy Hospitals, San Diego, CA ¶Orlando Health, Orlando, FL §University of Southhampton, Southampton General Hospital, Hampshire, England.

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December 2015

Differences in childhood adiposity influence upper limb fracture site.

Bone 2015 Oct 29;79:88-93. Epub 2015 May 29.

Paediatric Endocrinology, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton SO16 6YD, UK.

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October 2015

Shelf acetabuloplasty for containment in the early stages of Legg-Calve-Perthes disease.

J Pediatr Orthop 2015 Mar;35(2):151-6

Department of Child Health, University Hospital Southampton, Southampton, Hampshire, UK.

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March 2015

Failed Pavlik harness treatment for DDH as a risk factor for avascular necrosis.

J Pediatr Orthop 2015 Mar;35(2):140-3

*University Hospital Southampton Foundation Trust; Southampton General Hospital †NIHR Research Design Service South Central ‡University of Southampton and Child Health, University Hospital Southampton Foundation Trust, Southampton General Hospital, Southampton, UK.

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March 2015

Clinically led performance management in secondary healthcare: evaluating the attitudes of medical and non-clinical managers.

BMJ Qual Saf 2015 Mar 27;24(3):212-20. Epub 2015 Jan 27.

Department of Human Resources, School of Management, University of Southampton, Southampton, UK.

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March 2015

Comparison of uptake of colorectal cancer screening based on fecal immunochemical testing (FIT) in males and females: a systematic review and meta-analysis.

Cancer Epidemiol Biomarkers Prev 2015 Jan 6;24(1):39-47. Epub 2014 Nov 6.

Department of Epidemiology and Public Health, University College Cork, Cork, Ireland.

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January 2015

Treatment and prevention of hip dysplasia in infants and young children.

Early Hum Dev 2014 Nov 11;90(11):731-4. Epub 2014 Sep 11.

Child Health, University Hospital Southampton Foundation Trust, Southampton, UK; Faculty of Medicine, University of Southampton, Southampton, UK. Electronic address:

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November 2014

A review of environmental factors implicated in human developmental dysplasia of the hip.

J Child Orthop 2014 Oct 25;8(5):375-9. Epub 2014 Oct 25.

Trauma and Orthopaedics, University Hospital Southampton NHS Foundation Trust, Southampton, England, UK.

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October 2014

Developmental dysplasia of the hip: diagnosis and management to 18 months.

Instr Course Lect 2014 ;63:307-11

Professor and Consultant Orthopaedic Surgeon, Department of Child Health, University Hospital Southampton, Southampton, United Kingdom.

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September 2014

Incomplete periacetabular acetabuloplasty--reply.

Acta Orthop 2014 Aug;85(4):446

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August 2014

Development and cross-national validation of the Emotional Effort Scale (EEF).

Psicothema 2013 ;25(3):363-9

Northampton Business School, University of Northampton, Northampton, Reino Unido.

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July 2014

Increasing late stage colorectal cancer and rectal cancer mortality demonstrates the need for screening: a population based study in Ireland, 1994-2010.

BMC Gastroenterol 2014 May 13;14:92. Epub 2014 May 13.

National Cancer Registry, Building 6800, Cork Airport Business Park, Kinsale Road, Cork, Ireland.

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May 2014

Is the water footprint an appropriate tool for forestry and forest products: the Fennoscandian case.

Ambio 2014 Mar 19;43(2):244-56. Epub 2013 Feb 19.

Joensuu Research Unit, Finnish Forest Research Institute, P.O. Box 68, 80101, Joensuu, Finland,

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March 2014

Incomplete periacetabular acetabuloplasty.

Acta Orthop 2014 Feb 24;85(1):66-70. Epub 2014 Jan 24.

University Hospital Southampton NHS Foundation Trust, Southampton.

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February 2014

Transfer of training: the missing link in training and the quality of adult social care.

Authors:
Nicholas Clarke

Health Soc Care Community 2013 Jan 18;21(1):15-25. Epub 2012 Jul 18.

School of Management, University of Southampton, UK.

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January 2013

Digital calcinosis circumscripta: case series and review of the literature.

J Pediatr Orthop B 2012 Sep;21(5):443-7

Southampton General Hospital, Southampton, Hants, UK.

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September 2012

Personnel and unit factors impacting outcome after cardiac arrest in a dedicated pediatric cardiac intensive care unit.

Pediatr Crit Care Med 2012 Sep;13(5):583-8

Division of Cardiology, Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI, USA.

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September 2012

Strategies to improve nonoperative childhood management.

Orthop Clin North Am 2012 Jul;43(3):281-9

Southampton General Hospital, Southampton, United Kingdom.

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July 2012

The incidence of fractures in children under the age of 24 months--in relation to non-accidental injury.

Injury 2012 Jun 19;43(6):762-5. Epub 2011 Sep 19.

Southampton University Hospitals NHS Trust, MP 817, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, United Kingdom.

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June 2012

Managing bone and joint infection in children.

Arch Dis Child 2012 Jun 22;97(6):545-53. Epub 2012 Mar 22.

Clinical and Experimental Sciences, University of Southampton, Southampton, UK.

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June 2012

Twenty years experience of selective secondary ultrasound screening for congenital dislocation of the hip.

Arch Dis Child 2012 May 12;97(5):423-9. Epub 2012 Mar 12.

Department of Child Health, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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May 2012

Vitamin D deficiency: a paediatric orthopaedic perspective.

Curr Opin Pediatr 2012 Feb;24(1):46-9

University Hospital Southampton, NHS Foundation Trust Southampton University Hospitals, Southampton General Hospital, Southampton, Hampshire, UK.

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February 2012

Comparison of Ponseti versus surgical treatment in congenital talipes equinovarus.

J Foot Ankle Surg 2011 Sep-Oct;50(5):529-34. Epub 2011 Jun 15.

Southampton General Hospital, Southampton, UK.

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January 2012

Sugioka transtrochanteric valgus osteotomy for hinge abduction in children.

J Pediatr Orthop 2011 Oct-Nov;31(7):727-31

Southampton University Hospitals NHS Trust, Southampton, United Kingdom.

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January 2012

Epidemiology of vitamin D deficiency in children presenting to a pediatric orthopaedic service in the UK.

J Pediatr Orthop 2011 Oct-Nov;31(7):798-802

Pediatric Endocrinology, Southampton General Hospital, Southampton, UK.

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January 2012

Effect on soil chemistry of genetically modified (GM) vs. non-GM maize.

GM Crops 2010 May-Jun;1(3):157-61

Jilin Academy of Agricultural Sciences, Changchun, China.

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December 2011

Antipsychotic medication is associated with selective alterations in ventricular cerebrospinal fluid Aβ 40 and tau in patients with intractable unipolar depression.

Int J Geriatr Psychiatry 2011 Dec 9;26(12):1283-91. Epub 2011 Feb 9.

King's College London, Wolfson Centre for Age-Related Diseases, London, UK.

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December 2011

Standardized diagnostic criteria for developmental dysplasia of the hip in early infancy.

Clin Orthop Relat Res 2011 Dec 28;469(12):3451-61. Epub 2011 Sep 28.

Department of Orthopaedic Surgery, Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK.

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December 2011

Outcome of distal tibial physeal injuries.

J Pediatr Orthop B 2011 Jul;20(4):242-8

Department of Paediatric Orthopaedics, Southampton University Hospitals NHS Trust, Tremona Road, Southampton, UK.

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July 2011

Bilateral acromial fractures in a neonate with epileptic encephalopathy.

Pediatr Radiol 2011 Jun 13;41(6):788-9. Epub 2011 Jan 13.

Department of Paediatric Radiology, Southampton General Hospital, Tremona Road, Southampton, Hampshire, SO16 6YD, UK.

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June 2011

The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation.

Biomaterials 2010 Feb 18;31(6):1242-50. Epub 2009 Nov 18.

Bone & Joint Research Group, Centre for Human Development, Stem Cells and Regeneration, Developmental Origins of Health and Disease, Institute of Developmental Sciences, University of Southampton, General Hospital, Southampton, SO16 6YD, UK.

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February 2010

Inhaled muscarinic antagonists for COPD--does an anti-inflammatory mechanism really play a role?

Curr Opin Pharmacol 2009 Jun 13;9(3):250-5. Epub 2009 Mar 13.

Allergy and Respiratory Biology, Pfizer Global R&D, Sandwich, Kent, UK.

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June 2009

Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage.

J Orthop Res 2009 May;27(5):593-601

Bone and Joint Research Group, University of Southampton, Southampton, United Kingdom.

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May 2009

Influence of QA/QC procedures on non-sampling error in deposition monitoring in forests.

J Environ Monit 2009 Apr 27;11(4):745-50. Epub 2009 Feb 27.

CNR Institute for Ecosystem Study, Largo Tonolli 50, Verbania Pallanza, Italy. a.marchetto@ ise.cnr.it

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April 2009

The formation and fate of chlorinated organic substances in temperate and boreal forest soils.

Environ Sci Pollut Res Int 2009 Mar 23;16(2):127-43. Epub 2008 Dec 23.

Norwegian Forest and Landscape Institute, P.O. Box 115, 1431, As, Norway.

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March 2009

Group II introns in eubacteria and archaea: ORF-less introns and new varieties.

RNA 2008 Sep 1;14(9):1704-13. Epub 2008 Aug 1.

Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada.

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September 2008

Acute haematogenous osteomyelitis in children: is there any evidence for how long we should treat?

Curr Opin Infect Dis 2008 Jun;21(3):258-62

Paediatric Infectious Diseases Unit, St George's Hospital, London, UK.

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June 2008

The effect of mesenchymal populations and vascular endothelial growth factor delivered from biodegradable polymer scaffolds on bone formation.

Biomaterials 2008 Apr 29;29(12):1892-900. Epub 2008 Jan 29.

Bone and Joint Research Group, Centre for Human Development, Stem Cells and Regeneration, Developmental Origins of Health and Disease, Institute of Developmental Sciences, University of Southampton, Southampton, UK.

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April 2008

Genetic regulation of embryological limb development with relation to congenital limb deformity in humans.

J Child Orthop 2008 Feb 7;2(1):1-9. Epub 2008 Feb 7.

MP817, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK,

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February 2008

Pseudoparalysis in the Pavlik Harness: beware of septic arthritis.

J Child Orthop 2007 Nov 13;1(5):287-9. Epub 2007 Oct 13.

Department of Orthopaedics, Southampton University Hospitals, Southampton, UK.

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November 2007

Relapse rates following staged surgery in the treatment of recalcitrant talipes equinovarus: 9- to 16-year outcome study.

J Child Orthop 2007 Jul 23;1(2):115-9. Epub 2007 Jun 23.

Trauma and Orthopaedics, Southampton General Hospital, Southampton University Hospitals NHS Trust, Tremona Road, Southampton, SO16 6YD, UK.

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July 2007

Predicting the outcome of Legg-Calve-Perthes' disease in children under 6 years old.

J Child Orthop 2007 Jul;1(2):159

Department of Orthopaedics, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.

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July 2007

Predicting the outcome of Legg-Calve-Perthes' disease in children under 6 years old.

J Child Orthop 2007 Mar 9;1(1):27-32. Epub 2007 Feb 9.

Department of Orthopaedics, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.

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March 2007

Aluminum dynamics in forest soil waters in Norway.

Sci Total Environ 2006 Aug 31;367(2-3):942-57. Epub 2006 Mar 31.

Norwegian Forest Research Institute, Høgskoleveien 8, N-1432 As, Norway.

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August 2006

Determining the best ventilatory efficiency measure to predict mortality in patients with heart failure.

J Heart Lung Transplant 2006 May 23;25(5):589-95. Epub 2006 Mar 23.

Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48106, USA.

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May 2006

Perthes' disease in the very young child.

J Pediatr Orthop B 2006 Jan;15(1):16-22

Department of Orthopaedics, Southampton General Hospital, Southampton, UK.

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January 2006