Nicholas B Larson

Nicholas B Larson

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Nicholas B Larson

Nicholas B Larson

Publications by authors named "Nicholas B Larson"

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Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in and .

Drug Metab Dispos 2019 04 11;47(4):425-435. Epub 2019 Feb 11.

Departments of Molecular Pharmacology and Experimental Therapeutics (S.D., I.M., M.-F.H., L.W., R.M.W., J.M.R.) and Health Sciences Research (N.B.L., S.J.B.), Personalized Genomics Laboratory, Department of Laboratory Medicine and Pathology (A.M.M., J.L.B.), and Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Graduate School of Biomedical Sciences (D.R.N.), Mayo Clinic, Rochester, Minnesota; and Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas (S.E.S.)

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http://dx.doi.org/10.1124/dmd.118.084269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423619PMC
April 2019

A review of kernel methods for genetic association studies.

Genet Epidemiol 2019 03 2;43(2):122-136. Epub 2019 Jan 2.

Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/gepi.22180
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http://dx.doi.org/10.1002/gepi.22180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375780PMC
March 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 Jan 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Improving Single-Nucleotide Polymorphism-Based Fetal Fraction Estimation of Maternal Plasma Circulating Cell-Free DNA Using Bayesian Hierarchical Models.

J Comput Biol 2018 09 22;25(9):1040-1049. Epub 2018 Jun 22.

1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic , Rochester, Minnesota.

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https://www.liebertpub.com/doi/10.1089/cmb.2018.0056
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http://dx.doi.org/10.1089/cmb.2018.0056DOI Listing
September 2018

From genome-wide associations to candidate causal variants by statistical fine-mapping.

Nat Rev Genet 2018 08;19(8):491-504

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41576-018-0016-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050137PMC
August 2018

Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.

Cell 2018 07 19;174(3):564-575.e18. Epub 2018 Jul 19.

Princess Margaret Cancer Center, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.06.014DOI Listing
July 2018

Yield of the Genetic Test in Suspected Catecholaminergic Polymorphic Ventricular Tachycardia and Implications for Test Interpretation.

Circ Genom Precis Med 2018 02;11(2):e001424

From the Mayo Clinic School of Medicine (J.D.K., M.J.A.), Medical Scientist Training Program (J.D.K., M.J.A.), Mayo Clinic Graduate School of Biomedical Sciences, Department of Molecular Pharmacology and Experimental Therapeutics, Windland Smith Rice Sudden Death Genomics Laboratory (J.D.K., D.J.T., M.J.A.), Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (N.B.L.), Division of Heart Rhythm Services, Department of Cardiovascular Diseases (D.J.T., M.J.A.), and Division of Pediatric Cardiology, Department of Pediatrics (M.J.A.), Mayo Clinic, Rochester, MN; Department of Medicine, Stanford University, Stanford, CA (K.N.P.); Transgenomic Inc, New Haven, CT (T.E.C.); and Department of Clinical Genetics (H.B.) and Heart Centre, Department of Clinical and Experimental Cardiology (A.A.M.W.), Academic Medical Center, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1161/CIRCGEN.116.001424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364978PMC
February 2018

An integrative approach to assess X-chromosome inactivation using allele-specific expression with applications to epithelial ovarian cancer.

Genet Epidemiol 2017 12 8;41(8):898-914. Epub 2017 Nov 8.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1002/gepi.22091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726546PMC
December 2017

Hepatocyte Growth Factor Is Positively Associated With Risk of Stroke: The MESA (Multi-Ethnic Study of Atherosclerosis).

Stroke 2016 11 11;47(11):2689-2694. Epub 2016 Oct 11.

From the Division of Epidemiology (E.J.B., S.J.B.) and Division of Biomedical Statistics and Informatics (N.B.L., P.A.D.), Department of Health Sciences Research, Mayo Clinic, Rochester, MN; Division of Epidemiology and Community Health (J.S.P.) and Laboratory of Medicine and Pathology (M.Y.T., N.Q.H.), University of Minnesota, Minneapolis; Department of Pathology and Laboratory Medicine, College of Medicine, University of Vermont, Colchester (C.L.W.); and Departments of Neurology and Epidemiology, University of Washington, Seattle, WA (W.T.L.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079769PMC
http://dx.doi.org/10.1161/STROKEAHA.116.014172DOI Listing
November 2016

Improvement in Cardiovascular Risk Prediction with Electronic Health Records.

J Cardiovasc Transl Res 2016 06 9;9(3):214-22. Epub 2016 Mar 9.

Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s12265-016-9687-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874910PMC
June 2016

Regularized rare variant enrichment analysis for case-control exome sequencing data.

Genet Epidemiol 2014 Feb 30;38(2):104-13. Epub 2013 Dec 30.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1002/gepi.21783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985431PMC
February 2014

Kernel canonical correlation analysis for assessing gene-gene interactions and application to ovarian cancer.

Eur J Hum Genet 2014 Jan 17;22(1):126-31. Epub 2013 Apr 17.

1] Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA [2] Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA.

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http://dx.doi.org/10.1038/ejhg.2013.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865403PMC
January 2014

A kernel regression approach to gene-gene interaction detection for case-control studies.

Genet Epidemiol 2013 Nov 19;37(7):695-703. Epub 2013 Jul 19.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/gepi.21749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800261PMC
November 2013

PurBayes: estimating tumor cellularity and subclonality in next-generation sequencing data.

Bioinformatics 2013 Aug 6;29(15):1888-9. Epub 2013 Jun 6.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55901, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712213PMC
August 2013