Nicholas A Watkins

Nicholas A Watkins

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Nicholas A Watkins

Nicholas A Watkins

Publications by authors named "Nicholas A Watkins"

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39Publications

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Evidence-Based Policy and Practice Leads to Changes in the Criteria for MSM to Donate Blood.

Transfus Med Hemother 2013 Jun 17;40(3):155-8. Epub 2013 May 17.

Division of Health Sciences, Medical School, University of Warwick, Birmingham, UK.

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http://dx.doi.org/10.1159/000351770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725011PMC
June 2013

The management of blood safety in the presence of uncertain risk: a United kingdom perspective.

Transfus Med Rev 2012 Jul 29;26(3):238-51. Epub 2011 Nov 29.

National Health Service Blood and Transplant, Cambridge, UK.

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http://dx.doi.org/10.1016/j.tmrv.2011.09.003DOI Listing
July 2012

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation.

Br J Haematol 2010 Feb 8;148(4):627-37. Epub 2009 Dec 8.

Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Whiteknights, Reading, Berkshire.

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http://dx.doi.org/10.1111/j.1365-2141.2009.07994.xDOI Listing
February 2010

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

Nat Genet 2009 Nov 11;41(11):1182-90. Epub 2009 Oct 11.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108459PMC
November 2009

A single-nucleotide polymorphism in the human ITGB3 gene is associated with the platelet-specific alloantigen Va (HPA-17bw) involved in fetal maternal alloimmune thrombocytopenia.

Transfusion 2008 Jul 15;48(7):1432-8. Epub 2008 May 15.

The Department of Haematology, University of Cambridge and NHS Blood and Transplant, Cambridge, UK.

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http://dx.doi.org/10.1111/j.1537-2995.2008.01737.xDOI Listing
July 2008

Identification of variation in the platelet transcriptome associated with glycoprotein 6 haplotype.

Platelets 2008 Jun;19(4):258-67

Department of Haematology, University of Cambridge and National Health Service Blood and Transplant, Cambridge, UK.

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http://dx.doi.org/10.1080/09537100801947434DOI Listing
June 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ng.2007.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro.

Blood 2007 Jun 20;109(11):4806-9. Epub 2007 Feb 20.

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Addembrookes Hospital, Hills Road, Cambridge, UK.

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http://dx.doi.org/10.1182/blood-2006-09-047449DOI Listing
June 2007

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.

Proc Natl Acad Sci U S A 2007 Apr 13;104(17):7169-74. Epub 2007 Apr 13.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0608889104
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http://dx.doi.org/10.1073/pnas.0608889104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855357PMC
April 2007

A naturally occurring LeuVal mutation in beta3-integrin impairs the HPA-1a epitope: the third allele of HPA-1.

Transfusion 2006 May;46(5):790-9

Institute for Clinical Immunology and Transfusion Medicine, Justus Liebig University, Giessen, Germany.

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http://dx.doi.org/10.1111/j.1537-2995.2006.00797.xDOI Listing
May 2006

Platelet genomics and proteomics in human health and disease.

J Clin Invest 2005 Dec;115(12):3370-7

Department of Haematology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1172/JCI26885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297260PMC
December 2005

Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts.

Nat Med 2005 Oct 18;11(10):1056-8. Epub 2005 Sep 18.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1038/nm1288DOI Listing
October 2005

NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.

J Biol Chem 2004 Aug 3;279(33):34963-70. Epub 2004 Jun 3.

Medical Research Council Centre for Protein Engineering, Hills Road, Cambridge CB2 2QH, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M405016200DOI Listing
August 2004

Single-chain antibody fragments derived from a human synthetic phage-display library bind thrombospondin and inhibit sickle cell adhesion.

Blood 2003 Jul 27;102(2):718-24. Epub 2003 Mar 27.

Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA.

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http://dx.doi.org/10.1182/blood-2002-11-3497DOI Listing
July 2003

Platelet alphaIIbbeta3 recombinant autoantibodies from the B-cell repertoire of a post-transfusion purpura patient.

Br J Haematol 2002 Mar;116(3):677-85

Division of Transfusion Medicine, University of Cambridge, Department of Haematology, Cambridge, UK.

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http://dx.doi.org/10.1046/j.0007-1048.2001.03301.xDOI Listing
March 2002