Nichola Cruickshanks

Nichola Cruickshanks

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Nichola Cruickshanks

Nichola Cruickshanks

Publications by authors named "Nichola Cruickshanks"

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34Publications

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The p53 Pathway in Glioblastoma.

Cancers (Basel) 2018 Sep 1;10(9). Epub 2018 Sep 1.

Department of Microbiology, Immunology & Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.3390/cancers10090297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162501PMC
September 2018

p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.

Glia 2018 05 2;66(5):999-1015. Epub 2018 Feb 2.

Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, 1340 Jefferson Park Ave, Charlottesville, Virginia.

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http://dx.doi.org/10.1002/glia.23297DOI Listing
May 2018

Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma.

Cancers (Basel) 2017 Jul 11;9(7). Epub 2017 Jul 11.

Department of Neurology and The Cancer Center, Department of Microbiology, Immunology & Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.

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http://www.mdpi.com/2072-6694/9/7/87
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http://dx.doi.org/10.3390/cancers9070087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532623PMC
July 2017

When to screen and not to screen.

Cancer Biol Ther 2014 14;15(2):147-8. Epub 2014 Jan 14.

Department of Biochemistry; Virginia Commonwealth University; Richmond, VA USA.

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http://dx.doi.org/10.4161/cbt.27741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115864PMC
May 2016

Differential regulation of autophagy and cell viability by ceramide species.

Cancer Biol Ther 2015 ;16(5):733-42

a Department of Biochemistry and Molecular Biology; Virginia Commonwealth University ; Richmond , VA , USA.

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http://dx.doi.org/10.1080/15384047.2015.1026509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623104PMC
March 2016

Nexavar/Stivarga and viagra interact to kill tumor cells.

J Cell Physiol 2015 Sep;230(9):2281-98

Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1002/jcp.24961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835179PMC
September 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://www.ilcambiamento.it/files/carcinogenesi.pdf
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

Mol Cancer Ther 2014 Oct 7;13(10):2384-98. Epub 2014 Aug 7.

Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185238PMC
October 2014

PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells.

Cancer Biol Ther 2014 Jun 20;15(6):758-67. Epub 2014 Mar 20.

Department of Biochemistry; Virginia Commonwealth University; Richmond, VA USA.

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http://dx.doi.org/10.4161/cbt.28553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049791PMC
June 2014

The role of cell signalling in the crosstalk between autophagy and apoptosis.

Cell Signal 2014 Mar 2;26(3):549-55. Epub 2013 Dec 2.

Department of Neurosurgery, Virginia Commonwealth University, 401 College St, Richmond, VA 23298, United States; Virginia Institute of Molecular Medicine, Virginia Commonwealth University, 401 College St, Richmond, VA 23298, United States.

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http://dx.doi.org/10.1016/j.cellsig.2013.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054685PMC
March 2014

HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells.

Cancer Biol Ther 2014 Mar 18;15(3):305-16. Epub 2013 Dec 18.

Department of Neurosurgery; Virginia Commonwealth University; Richmond, VA USA.

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http://dx.doi.org/10.4161/cbt.27309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974832PMC
March 2014

Phosphodiesterase 5 inhibitors enhance chemotherapy killing in gastrointestinal/genitourinary cancer cells.

Mol Pharmacol 2014 Mar 18;85(3):408-19. Epub 2013 Dec 18.

Departments of Biochemistry and Molecular Biology (L.B., J.L.R., N.C., A.C., P.D.), Cardiology (D.E.D., A.D., R.C.K.), Medicine (S.G., A.P.), Human and Molecular Genetics (P.B.F.), Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1124/mol.113.090043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935155PMC
March 2014

Sorafenib/regorafenib and phosphatidyl inositol 3 kinase/thymoma viral proto-oncogene inhibition interact to kill tumor cells.

Mol Pharmacol 2013 Oct 22;84(4):562-71. Epub 2013 Jul 22.

Departments of Neurosurgery (G.B.S., H.A.H., N.C., L.B., S.T., J.S., P.D.) and Medicine (S.G., A.P.), Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1124/mol.113.088005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781387PMC
October 2013

PARP and CHK inhibitors interact to cause DNA damage and cell death in mammary carcinoma cells.

Cancer Biol Ther 2013 May;14(5):458-65

Department of Neurosurgery, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.4161/cbt.24424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672190PMC
May 2013

Lapatinib and obatoclax kill breast cancer cells through reactive oxygen species-dependent endoplasmic reticulum stress.

Mol Pharmacol 2012 Dec 18;82(6):1217-29. Epub 2012 Sep 18.

Department of Neurosurgery, School of Medicne, Virginia Commonwealth University, Richmond, VA 23298-0035, USA.

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http://dx.doi.org/10.1124/mol.112.081539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502625PMC
December 2012

OSU-03012 interacts with lapatinib to kill brain cancer cells.

Cancer Biol Ther 2012 Dec 18;13(14):1501-11. Epub 2012 Sep 18.

Department of Neurosurgery, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.4161/cbt.22275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542242PMC
December 2012

Lapatinib and obatoclax kill tumor cells through blockade of ERBB1/3/4 and through inhibition of BCL-XL and MCL-1.

Mol Pharmacol 2012 May 22;81(5):748-58. Epub 2012 Feb 22.

Department of Neurosurgery, Virginia Commonwealth University, Richmond, VA 23298-0035, USA.

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http://dx.doi.org/10.1124/mol.112.077586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336802PMC
May 2012

Obatoclax and lapatinib interact to induce toxic autophagy through NOXA.

Mol Pharmacol 2012 Apr 4;81(4):527-40. Epub 2012 Jan 4.

Department of Neurosurgery, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298-0035, USA.

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http://dx.doi.org/10.1124/mol.111.076851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310419PMC
April 2012

Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death.

Cancer Biol Ther 2011 Aug 1;12(3):215-28. Epub 2011 Aug 1.

Department of Neurosurgery, Virginia Commonwealth University, School of Medicine, Richmond, VA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230482PMC
http://dx.doi.org/10.4161/cbt.12.3.16218DOI Listing
August 2011

Can hsp90alpha-targeted siRNA combined with TMZ be a future therapy for glioma?

Cancer Invest 2010 Jul;28(6):608-14

Brain Tumour North West, Faculty of Science and Technology, University of Central Lancashire, Preston, United Kingdom.

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http://dx.doi.org/10.3109/07357901003630967DOI Listing
July 2010

Can the lack of HSP90alpha protein in brain normal tissue and cell lines, rationalise it as a possible therapeutic target for gliomas?

Cancer Invest 2008 Nov;26(9):900-4

Neurosurgery Department, Royal Preston Hospital, Brain Tumor North West, Preston, UK.

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http://dx.doi.org/10.1080/07357900802087259DOI Listing
November 2008

Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma.

Brain Res 2007 Feb 2;1134(1):45-52. Epub 2007 Jan 2.

Department of Biological Sciences, University of Central Lancashire, and Neurosurgery Department, Royal Preston Hospital, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S000689930603510
Publisher Site
http://dx.doi.org/10.1016/j.brainres.2006.11.093DOI Listing
February 2007