Publications by authors named "Nguyen Minh Duc"

185 Publications

The value of quantitative magnetic resonance imaging signal intensity in distinguishing between spinal meningiomas and schwannomas.

Int J Med Sci 2022 21;19(7):1110-1117. Epub 2022 Jun 21.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Prior studies have suggested a number of the subjective visual characteristics that help distinguish between spinal meningiomas and schwannomas on magnetic resonance imaging and computed tomography; however, objective quantification of the signal intensity can be useful information. This study assessed whether quantitative magnetic resonance imaging (MRI) signal intensity (SI) measurements could distinguish intradural-extramedullary schwannomas from meningiomas. From July 2019 to September 2021, 54 patients with intradural-extramedullary tumors (37 meningiomas and 17 schwannomas) underwent surgery, and tumors were verified pathologically. Defined regions of interest were used to quantify SI values on T1- (T1W) and T2-weighted images (T2W). Receiver operating characteristic curve analysis was used to obtain cutoff values and calculate the area under the curve (AUC), sensitivity (SE), specificity (SP), positive predictive value (PPV), and negative predictive value (NPV). Both Maximum (T2) and mean (T2) T2W SI values demonstrated outstanding (AUC: 0.91) abilities to differentiate meningiomas from schwannomas with Se, Sp, PPV, and NPV values of 94.6%, 70.6%, 87.5%, and 85.7%, respectively, for T2 and 81.1%, 88.2%, 93.8%, and 68.2% for T2. The maximum SI value on contrast-enhanced T1W (T1CE) and the T2W tumor: fat SI ratio (rTF) demonstrated acceptable abilities (AUC: 0.73 and 0.79, respectively) to differentiate meningiomas from schwannomas with Se, Sp, PPV, and NPV values of 94.6%, 70.6%, 87.5%, and 85.7%, respectively, for T1CE and 81.1%, 88.2%, 93.8%, and 68.2% for rTF. Quantitative SI values (T2, T2 T2, T1CE, rTF) can be used to differentiate intradural-extramedullary schwannomas from meningiomas.
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http://dx.doi.org/10.7150/ijms.73319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339414PMC
August 2022

The value of quantitative magnetic resonance imaging signal intensity in distinguishing between spinal meningiomas and schwannomas.

Int J Med Sci 2022 21;19(7):1110-1117. Epub 2022 Jun 21.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Prior studies have suggested a number of the subjective visual characteristics that help distinguish between spinal meningiomas and schwannomas on magnetic resonance imaging and computed tomography; however, objective quantification of the signal intensity can be useful information. This study assessed whether quantitative magnetic resonance imaging (MRI) signal intensity (SI) measurements could distinguish intradural-extramedullary schwannomas from meningiomas. From July 2019 to September 2021, 54 patients with intradural-extramedullary tumors (37 meningiomas and 17 schwannomas) underwent surgery, and tumors were verified pathologically. Defined regions of interest were used to quantify SI values on T1- (T1W) and T2-weighted images (T2W). Receiver operating characteristic curve analysis was used to obtain cutoff values and calculate the area under the curve (AUC), sensitivity (SE), specificity (SP), positive predictive value (PPV), and negative predictive value (NPV). Both Maximum (T2) and mean (T2) T2W SI values demonstrated outstanding (AUC: 0.91) abilities to differentiate meningiomas from schwannomas with Se, Sp, PPV, and NPV values of 94.6%, 70.6%, 87.5%, and 85.7%, respectively, for T2 and 81.1%, 88.2%, 93.8%, and 68.2% for T2. The maximum SI value on contrast-enhanced T1W (T1CE) and the T2W tumor: fat SI ratio (rTF) demonstrated acceptable abilities (AUC: 0.73 and 0.79, respectively) to differentiate meningiomas from schwannomas with Se, Sp, PPV, and NPV values of 94.6%, 70.6%, 87.5%, and 85.7%, respectively, for T1CE and 81.1%, 88.2%, 93.8%, and 68.2% for rTF. Quantitative SI values (T2, T2 T2, T1CE, rTF) can be used to differentiate intradural-extramedullary schwannomas from meningiomas.
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http://dx.doi.org/10.7150/ijms.73319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339414PMC
August 2022

Diagnosis of symmetric bilateral lateral ventricular subependymomas: A case report.

Exp Ther Med 2022 Aug 8;24(2):503. Epub 2022 Jun 8.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City 700000, Vietnam.

Subependymomas are rare benign tumors that are hypovascular and noninvasive. Subependymomas tend to present as solitary lesions in the fourth ventricle or the frontal horn of the lateral ventricle. When multiple lesions are present, determining the correct diagnosis between subependymoma and other intraventricular neoplasms can be challenging. The characterization of imaging features and enhancement patterns can help narrow down the list of potential differential diagnoses. In this article, we describe a case of bilateral subependymomas in the lateral ventricles in a 40-year-old Asian man, including the clinical features, imaging results from conventional magnetic resonance imaging, magnetic resonance spectroscopy, and magnetic resonance perfusion, histological outcomes, and the disease management approach.
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http://dx.doi.org/10.3892/etm.2022.11429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257959PMC
August 2022

A rare case of fusiform basilar trunk aneurysm.

Radiol Case Rep 2022 Sep 4;17(9):3256-3259. Epub 2022 Jul 4.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Aneurysms in the posterior circulation and distal sites are more common among the pediatric population than among adults, with a male predominance. Symptoms of an aneurysm in the posterior circulation can include a stiff neck or severe headache due to a ruptured aneurysm, whereas an unruptured aneurysm can cause mass effects or neurological deficits. However, in children, the complete occlusion of the aneurysm while preserving the flow of the main artery can be difficult to achieve when attempting a stent-assisted coil embolization technique. A 25-month-old girl presented with left hemiparesis and was diagnosed with a basilar artery aneurysm 10 months prior, but she did not receive any specific treatment. No history of trauma and no significant familial history were recorded. Angiography showed a fusiform aneurysm on the basilar artery trunk, which was successfully occluded using stent-assisted coiling following dual antiplatelet therapy with clopidogrel and aspirin. She was discharged with the complete restoration of motor deficits.
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http://dx.doi.org/10.1016/j.radcr.2022.06.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270206PMC
September 2022

A rare case of pleuropulmonary blastoma detected in fetus.

Radiol Case Rep 2022 Sep 4;17(9):3251-3255. Epub 2022 Jul 4.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Pleuropulmonary blastoma (PPB) is among the rarest malignant tumors diagnosed in children. PPBs can be histopathologically classified into 3 types: cystic tumor (type I), mixed cystic and solid tumor (type II), and pure solid tumor (type III). We describe a case of type III PPB that was detected in a prenatal fetus, confirmed using histopathological methods. To the best of our knowledge, this is the first case describing a type III PPB detected in a fetus. Prenatal ultrasonography is an excellent tool for detecting pulmonary lesions during the diagnostic phase, and the possibility of PPB should be considered when solid tumors are detected. Early detection can allow for the performance of full resection, leading to a better prognosis for this cancerous tumor.
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http://dx.doi.org/10.1016/j.radcr.2022.06.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270209PMC
September 2022

The efficacy of quantitative magnetic resonance imaging in the diagnosis of unstable L4/L5 degenerative spondylolisthesis.

Biomed Rep 2022 Aug 8;17(2):67. Epub 2022 Jun 8.

Department of Radiology, Hanoi Medical University, Hanoi 100000, Vietnam.

Lumbar degenerative spondylolisthesis (LDS) is a common degenerative disease that particularly affects the elderly. LDS can occur in any segment of the spine but is most commonly found in the L4/L5 segment. In the present study, a quantitative study of lumbar MRI measurements was conducted to identify predisposing factors indicative of spinal instability in patients with L4/L5 LDS. In total, 81 patients [58 patients in the stable group (SG) and 23 patients in the unstable group (UG)] who were diagnosed with L4/L5 LDS on X-ray and MRI between January 2021 and January 2022 were included in this study. Disk height, disk signal intensity on T1-weighted (T1W) and T2-weighted (T2W) images, facet joint fluid thickness, and ligamentum flavum thickness were measured on MRI, and the differences in these parameters between the two groups were evaluated. The receiver operating characteristic curve was generated, and the area under the curve (AUC), cut-off value, sensitivity (Se), specificity (Sp), positive predictive value (PPV), and negative predictive value (NPV) were calculated for parameters found to be significantly different between the two groups. The facet joint fluid was significantly thicker in the UG than in the SG (P<0.01), and a cut-off value of 1.45 mm was found to have an AUC of 0.77 and an SE, SP, PPV, and NPV of 73.9, 67.2, 69.3, and 69.77%, respectively. No significant differences were identified between the two groups for mean disk height, ligamentum flavum thickness, or disk signal intensity on T1W or T2W images. The facet joint fluid thickness on axial T2W images may represent a useful predictor of spinal instability in patients with LDS. Therefore, spinal instability should be assessed, and additional evaluation methods, such as standing lateral flexion-extension radiographs, should be performed when facet fluid is detected on lumbar MRI.
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http://dx.doi.org/10.3892/br.2022.1550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260153PMC
August 2022

Features of International Publications in Vietnamese Radiological Societies after The Enactment of 37/2018/QĐ-TTg.

Acta Inform Med 2022 Mar;30(1):48-52

Department of Radiology, Hanoi Medical University, Ha Noi, Vietnam.

Background: In Vietnam, after the enactment of 37/2018/QĐ-TTg, a distinct shift could be observed in the international publications by radiological societies.

Objctive: This study examined trends in the international publications achieved by Vietnamese radiological societies following the enactment of 37/2018/QĐ-TTg.

Methods: This retrospective study evaluated data that are freely accessible and available online and, therefore, did not require institutional review board approval. We assessed the publication characteristics of the members of four Vietnamese radiological societies: Vietnamese Society of Radiology and Nuclear Medicine (VSRNM, = 67); Radiological Society of Ho Chi Minh City (RSHCM, = 25); Vietnamese Society of Ultrasound in Medicine (VSUM, = 29); and Vietnamese Society of Interventional Radiology (VSIR, n = 18), following the enactment of 37/2018/QĐ-TTg.

Results: Following the enactment of 37/2018/QĐ-TTg, we observed that total publications, number of first authors, number of last authors, number of articles indexed in Web of Science, and number of articles indexed in Scopus were significantly higher for the VSRNM and VSIR than for the RSHCM and VSUM. All publication parameters were significantly higher men, individuals who secured professorship, PhD and Master's degree holders, public hospital employees, those in the radiological field, and those in the north and south regions, compared with the values for women, individuals without professorships, Specialist II and I degree holders, private hospital employees, those in the nuclear medicine field, and those in the middle region, respectively.

Conclusion: The enactment of 37/2018/QĐ-TTg triggered a new trend in international publication among the members of four Vietnamese radiological societies. However, strong discrepancies remain in total publications, number of first authors, number of last authors, number of articles indexed in Web of Science, and number of articles indexed in Scopus among the members of the four main Vietnamese radiological societies.
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http://dx.doi.org/10.5455/aim.2022.30.48-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226757PMC
March 2022

The Effectiveness of Sperm Preparation Using Density Mini-Gradient and Single-Layer Centrifugation for Oligospermia Samples.

Acta Inform Med 2022 Jun;30(2):100-104

Department of Histology and Embryology, Hanoi Medical University, Hanoi, Vietnam.

Background: Sperm preparation is an important step during assisted reproduction, and different assisted reproductive techniques have different sperm quality requirements. For intrauterine insemination (IUI), the total motile sperm count is a predictor of a patient's fertility.

Objective: The aim of this study was to compare the sperm recovery rate and DNA fragmentation index (DFI) outcomes following density mini-gradient and single-layer centrifugation in preparation for intrauterine insemination (IUI).

Methods: A total of 30 semen samples with concentrations under 15 million cells/ml were obtained, and each sample was divided into 3 aliquots, with each aliquot subjected to 1 of 3 separation methods: mini-gradient, single-layer using a 90% density layer (single 90-layer), and single-layer using a 45% density layer (single 45-layer). Total sperm motility and sperm recovery rates were compared before and after preparation using each method.

Results: The sperm concentration obtained using single 45-layer was higher than the other groups (p<0.05), but sperm motility was higher using the mini-gradient and single 90-layer methods higher than the single 45-layer method (p<0.05). The recovered sperm motility rates for the mini-gradient, single 90-layer, and single 45-layer methods were 57.6% ± 20.6%, 62.8% ± 18.5%, and 78.7% ± 12.4%, respectively, indicating a better outcome for the single 45-layer method than for the other methods.

Conclusion: All of these methods can be applied to sperm preparation for IUI, and the optimal method can be selected based on initial sperm quality to collect sperm with good motility and DNA integrity to achieve a satisfactory pregnancy rate.
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http://dx.doi.org/10.5455/aim.2022.30.100-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233458PMC
June 2022

Reconstruction of Dorsal Hand Burn Scars Using Microdissected Tailoring of the Free Anterolateral Thigh Flap.

Acta Inform Med 2022 Jun;30(2):125-128

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Background: Currently, large defects of the dorsum and finger of the hand pose a great challenge to plastic surgeons. The most difficult problem is finding a suitable material that has a large area and a thin, reliable blood supply and can be tailored into many small flaps to cover the fingers.

Case Series: We present the cases of two patients admitted to our hospital with scars on the dorsal side of the hand after gas burns. The defects after scar release were reconstructed by microdissected tailoring of the free anterolateral thigh flap. Complete survival was achieved for all flaps, including the small flaps tailored for finger defects. The function and aesthetics of the hands significantly improved. The patients were satisfied after the pain, itching, and burning symptoms of the scar were relieved.

Conclusion: Microdissected tailoring of the free anterolateral thigh flap is an ideal method for addressing hand defects. The microdissected tailoring technique allows the surgeon to construct a thin flap with a reliable blood supply from the perforator.
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http://dx.doi.org/10.5455/aim.2022.30.125-128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233477PMC
June 2022

Cutoff Values for Serum Ferritin in Predicting Cirrhosis Severity due to Cholestatic Jaundice in Vietnamese Children.

Med Arch 2022 Apr;76(2):122-126

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Background: High serum ferritin levels are associated with liver cirrhosis severity and worse outcomes for hepatopathies. This study determined the serum ferritin cutoff values for predicting cirrhosis severity in children with cholestatic jaundice.

Methods: A retrospective study was performed, including all cases diagnosed with cirrhosis in children aged 1 month to 16 years at Children's Hospital 2-Vietnam between 2016 and 2021. Receiver operating characteristic (ROC) curve analysis was used to estimate ferritin cutoff values for predicting disease severity.

Results: The study included 95 patients with cirrhosis due to cholestatic jaundice. Decompensated cirrhosis accounted for the majority (74.7%) of cases. Increased serum ferritin concentrations predicted cirrhosis severity in children, and the optimal ferritin cutoff value for predicting decompensated cirrhosis was determined to be 195 μg/l, resulting in a sensitivity of 65.22%, a specificity of 95.83%, and an area under the ROC curve (AUC) or 0.82. The Child-Pugh C group had higher ferritin levels than the Child-Pugh A and B group (p < 0.001), and the ferritin cutoff value for distinguishing between Child-Pugh classifications was 195 μg/l, resulting in a sensitivity of 71.2%, a specificity of 87.9%, and an AUC of 0.80.

Conclusions: Serum ferritin levels are significantly associated with decompensated cirrhosis and disease severity (as assessed by Child-Pugh score). Routine serum ferritin testing may contribute to predicting cirrhosis severity in children.
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http://dx.doi.org/10.5455/medarh.2022.76.122-126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233469PMC
April 2022

Preoperative embolization of hypervascular spinal tumors: Two case reports.

J Clin Imaging Sci 2022 2;12:21. Epub 2022 May 2.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

The performance of preoperative embolization on a spinal tumor can be a useful adjunctive procedure that minimizes blood loss and complications, particularly for both metastatic and non-metastatic hypervascular tumors. We discuss two cases of hypervascular spinal tumors that were successfully treated with preoperative embolization and surgery. The first patient was an 18-year-old man who presented with cervical and shoulder pain for two months without paralysis or weakness. Magnetic resonance imaging revealed a tumor located in the D2 posterior vertebral arch that extended into the spinal canal and compressed the spinal cord. The second patient was a 68-year-old man with back pain that radiated to the legs for ten days. Magnetic resonance imaging revealed a mass in the L4 vertebral body. Both patients received tumor embolization and surgery. After surgery, neither patient experienced any major complications. Histological examination revealed osteoblastoma in the first patient and plasmacytoma in the second patient.
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http://dx.doi.org/10.25259/JCIS_20_2022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168289PMC
May 2022

Prognostic Significance of PD-L1 Expression and Standardized Uptake Values in the Primary Lesions of Stage IV Adenocarcinoma Lung Cancer.

Front Med (Lausanne) 2022 13;9:895401. Epub 2022 May 13.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Background: This study evaluated the prognostic ability of F-fluorodeoxyglucose (F-FDG) positron emission tomography (PET)/computed tomography (CT) in patients with stage IV adenocarcinoma lung cancer to detect protein death-ligand 1 (PD-L1) expression levels.

Methods: In total, 86 patients with stage IV adenocarcinoma lung cancer underwent F-FDG PET/CT imaging and PD-L1 expression evaluation before treatment from February 2019 to November 2020 at Bach Mai Hospital, Hanoi, Vietnam. The assessed patient characteristics in this study included sex, age, smoking status, epidermal growth factor receptor () mutation, PD-L1 expression level, survival status, tumor, node, and metastasis (TNM) stage, and metastasis locations.

Results: The average age was 62.23 ± 9.51 years, and men and women represented 67.4% and 32.6% of the population, respectively. The mutation rate was 36%. PD-L1 expression was negative (detected in <1% of the tumor) in 40.7% of cases and positive in 59.3% of cases (detected in 1-49% of the tumor in 32.6%; detected in ≥50% of the tumor in 26.7%). The mean maximum standardized uptake value (SUV) was 11.09 ± 3.94. SUV was significantly higher in PD-L1-positive tumors than in PD-L1-negative tumors (12.24 ± 4.01 and 9.43 ± 3.22, respectively; = 0.001). Receiver operating characteristic curve analysis revealed an area under the curve of SUVmax was 0.681 (95% confidence interval 0.570-0.793, = 0.004). Compared with PD-L1-negative cases, SUV was significantly different in all PD-L1-positive cases ( = 0.001), weakly PD-L1-positive cases (1-49%, = 0.005), and strongly PD-L1-positive cases (≥50%, = 0.003). PD-L1 expression levels were significantly associated with SUV ( = 0.001), tumor size ( = 0.022), and mutation status ( = 0.045).

Conclusions: SUV in the primary lesions was able to predict PD-L1 expression and may play a role in predicting PD-L1 immunotherapy efficacy in patients with stage IV lung adenocarcinoma.
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http://dx.doi.org/10.3389/fmed.2022.895401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137395PMC
May 2022

Percutaneous transhepatic holmium laser lithotripsy for cholelithiasis and balloon dilation for common bile duct stone removal.

Radiol Case Rep 2022 Jul 12;17(7):2506-2509. Epub 2022 May 12.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.

Biliary lithiasis is common in clinical practice. We present the case of a 53-year-old man referred to our hospital with a history of biliary lithiasis. Abdominal magnetic resonance imaging revealed gallbladder stones and common bile duct stones. To avoid surgery, we opted to apply percutaneous transhepatic techniques to clear gallbladder and bile duct stones. This study reports our experience using these techniques, including percutaneous transhepatic holmium laser lithotripsy for cholelithiasis combined with balloon dilation to remove common bile duct stones and avoid open surgery.
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http://dx.doi.org/10.1016/j.radcr.2022.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114155PMC
July 2022

Pulmonary arteriovenous malformation and inherent complications with solitary lung nodule biopsy-literature overview and case report.

Radiol Case Rep 2022 Jul 6;17(7):2353-2361. Epub 2022 May 6.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Pulmonary arteriovenous malformation, also known as an arteriovenous fistula, is typically a congenital disease caused by structural deficiencies, particularly the lack of capillary wall development, leading to the abnormal dilation of the pulmonary capillaries. The majority of pulmonary arteriovenous malformation cases are associated with Rendu-Osler-Weber syndrome, also known as hereditary hemorrhagic telangiectasia. Pulmonary arteriovenous malformation rarely occurs due to chest trauma. Pulmonary arteriovenous malformations are long-lasting and often first diagnosed in adults. More than two-thirds of pulmonary arteriovenous malformation lesions are found in the lower lung lobe and the subpleural area, and the vast majority of cases present with the monofocal form. The initial diagnosis is often based on the identification of a solitary pulmonary nodule. However, a solitary nodule detected on chest computed tomography that is not correctly diagnosed as pulmonary arteriovenous malformation, even after intravenous contrast injection, can lead to the performance of a transthoracic biopsy. Biopsy of pulmonary arteriovenous malformations can lead to stroke occurrence, during which the patient often presents with severe pleural bleeding, which can have lifelong consequences if not immediately treated. We report a case of pulmonary arteriovenous malformation that was discovered incidentally in an adult patient who underwent non-contrast computed tomography. Misdiagnosis occurred, and transthoracic lung biopsy was performed. Complications were discovered late, and the patient underwent surgical pulmonary arteriovenous malformation removal and was treated for hemothorax.
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http://dx.doi.org/10.1016/j.radcr.2022.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096463PMC
July 2022

Percutaneous Transhepatic Cholecystolithotomy by Holmium Laser for Non-high-Risk Patients with Symptomatic Gallbladder Stones.

Med Arch 2022 Feb;76(1):29-33

Department of Radiology, Pham Ngoc Thach University of Medicine, Hanoi, Vietnam.

Background: The development of gallstones, also known as cholelithiasis, is one of the most common diseases associated with the gastrointestinal tract. In developing countries 10% to 15% of men and >25% of women experience gallstones.

Objective: The aim of the study was to evaluate the outcomes following percutaneous transhepatic cholecystolithotomy by holmium laser in non-high-risk patients with symptomatic gallbladder stones.

Methods: This was an intervention study without control and with longitudinal follow-up. Subjects included patients who had only gallbladder stones, a normal gallbladder contractility index, and required a conservative treatment.

Results: The study included 44 patients (20 men, 24 women), with a mean age of 41.5 ± 13.4 years. The success rate was 97.7%, and only 1 of 44 patients required follow-up laparoscopic cholecystectomy. Gallstones were successfully removed from 43 of 44 patients (97.7%). The complication rate was 13.6% (6/44 patients), and only minor complications were reported for 5 of the 6 patients with complications. In 34 of 43 patients, follow-up examinations were performed after 1 and 6 months. The gallstone recurrence rate at six-month follow-up was 11.8%, and a collapsed gallbladder was detected in 1 of 34 patients, with the remaining 33 patients retaining normal gallbladder contractility indices (>40%).

Conclusion: Percutaneous transhepatic cholecystolithotomy by holmium laser has a high gallstone removal rate (97.7%); however, recurrence remains a major problem. The complication rate was about 13.6%, most of which were minor complications. Cases associated with treatment failure or serious complications should be detected and treated promptly.
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http://dx.doi.org/10.5455/medarh.2022.76.29-33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976887PMC
February 2022

Dinoprostone Vaginal Insert for Induction of Labor in Women with Low-Risk Pregnancies: A Prospective Study.

Med Arch 2022 Feb;76(1):39-44

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Background: Induction of labor (IOL) is a technique to establish vaginal delivery when the risks for continuing the pregnancy for mother or baby are higher than the risks of delivery. It is usually performed in high-risk pregnancies, but can also be beneficial in low-risk populations, as shown in the ARRIVE trial.

Objective: To evaluate the effectiveness and safety of slow-release vaginal dinoprostone (prostaglandin E2 10 mg) for labor induction in women with low-risk pregnancies.

Methods: A prospective study was performed at Hanoi Obstetrics and Gynecology Hospital, Vietnam. We recruited women with low-risk pregnancies from 39 weeks + 0 days to 40 weeks + 6 days of gestation and an unfavorable cervix. Women who participated received 10 mg intravaginal slow-release dinoprostone (Propess) for induction of labor. Labor, deliveries, and post-partum management were performed according to the local protocol.

Results: From September 2020 to March 2021, 102 low-risk women were eligible to participate in the study. Among these women, 67.6% had vaginal deliveries, 6.9% had postpartum bleeding, and 3.9% experienced tachysystole. All newborns were healthy, with good APGAR scores. None of the women needed respiratory support or intensive care unit admission. All other maternal or fetal complications were explored. The rate of cesarean section was 3.8 higher in nulliparous than multiparous women and 2.2 times higher in women who did not receive epidural analgesia than in those who did. The risk of cesarean section increased if the time between labor induction and active labor was greater than 12.5 hours.

Conclusion: Slow-release dinoprostone insert is safe and effective for the induction of labor in low-risk pregnant women. The risk of cesarean section was elevated in nulliparous patients and those who did not receive epidural analgesia during labor. As the time from labor induction to active labor increased, the risk of cesarean section increased.
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http://dx.doi.org/10.5455/medarh.2022.76.39-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976886PMC
February 2022

Primary mediastinal lymph node tuberculosis diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration: Literature review and case report.

Radiol Case Rep 2022 May 23;17(5):1709-1717. Epub 2022 Mar 23.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Tuberculosis bacilli can enter the human body through the respiratory system, digestive system, or skin and mucous membranes, with the respiratory tract representing the primary point of entry. Once inside the body, tuberculosis bacilli can enter the bloodstream and attack other organs, including the lymphatic system. One manifestation associated with lymphatic tuberculosis infiltration is the presence of large hilar and mediastinal lymph nodes, which are common in children and classified as primary tuberculosis. A diagnosis of primary tuberculosis in adults is often overlooked by doctors due to its low frequency. When a single enlarged mediastinal lymph node is observed, most doctors suspect other causes, especially malignancy. Determining the correct diagnosis for enlarged hilar and mediastinal lymph nodes can be difficult because diagnostic interventions in this area are challenging to perform. We report a clinical case of primary lymph node tuberculosis in an adult, confirmed by endobronchial ultrasound-guided transbronchial needle aspiration. We aim to provide doctors with a more comprehensive approach for diagnosing this disease.
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http://dx.doi.org/10.1016/j.radcr.2022.02.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956921PMC
May 2022

Phlebosclerotic colitis with long-term herbal medicine use.

Radiol Case Rep 2022 May 22;17(5):1696-1701. Epub 2022 Mar 22.

Department of Radiology, Hanoi Medical University, Hanoi, Vietnam.

Phlebosclerotic colitis (PC), also known as idiopathic mesenteric phlebosclerosis, is a rare disease resulting in ischemic colon due to venous sclerosis and calcifications that can be identified by characteristic imaging features on computed tomography and colonoscopy. Clinical examination reveals nonspecific symptoms with slow progression in the majority of cases. Patients with PC often require late-stage hospitalization and colectomy. We report a 79-year-old man with long-term clinical symptoms who used herbal medicines. Computed tomography and colonoscopy studies revealed several classical PC characteristics, and the patient subsequently underwent emergency total colectomy.
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http://dx.doi.org/10.1016/j.radcr.2022.02.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942791PMC
May 2022

Primary lymphatic tuberculosis in children - Literature overview and case report.

Radiol Case Rep 2022 May 21;17(5):1656-1664. Epub 2022 Mar 21.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Tuberculosis bacilli can enter the human body through the digestive system, the skin, and the mucous membranes, although they mainly enter through the respiratory tract. TB bacilli can enter the bloodstream and attack other organs including the lymphatic system. The TB bacillus can cause miliary tuberculosis once they have entered the bloodstream and infiltrated the lymphatic system, which can then manifest as large lymph nodes in the hilum, mediastinum, and lung. Complicated primary TB infection occurs when enlarged lymph nodes compress the airways, causing a partial or complete obstruction that can lead to air retention or atelectasis. More serious complications can occur if the lymph nodes fill with pus and burst, as this can lead to TB spreading through the airways via a humoral mechanism. Making a differential diagnosis of hilar and mediastinal lymphadenopathy is often difficult because diagnostic interventions in this area are problematic. We report on a clinical case of a child with primary TB of the lymphatic system. The patient presented with mediastinal lymphadenopathy and miliary lesions in the lung, which was confirmed by a transthoracic biopsy performed under CT guidance. It is hoped that this report can provide doctors with a more comprehensive approach when diagnosing this disease.
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http://dx.doi.org/10.1016/j.radcr.2022.02.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942788PMC
May 2022

Pulmonary lymphangioleiomyomatosis (LAM): A literature overview and case report.

Radiol Case Rep 2022 May 21;17(5):1646-1655. Epub 2022 Mar 21.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Lymphangioleiomyomatosis is a rare multisystem disease associated with genetic mutations. The disease usually occurs in women of childbearing age and is characterized by infiltration of immature smooth muscle cells into the lungs, airways, and axial lymphatic systems of the chest and abdomen. The disease often destroys lung parenchyma and produces air cysts. Lymphangioleiomyomatosis cell infiltration of the lymphatic axis can affect hilar lymph nodes, mediastinal ganglia, and extrathoracic lymph nodes. The disease can cause lymphatic dilation in the lungs and thoracic ducts, causing chylous effusion into the pleural or abdominal cavities. Invasion of cells into the walls of pulmonary veins can lead to venous obstruction and pulmonary venous hypertension with hemoptysis. Most patients present with cough, dyspnea, pneumothorax, hemoptysis, and abnormal lung function. Definitive diagnosis is usually based on histopathology and immunohistochemistry. We present a case of LAM in a 36-year-old female patient who was confirmed by specimens obtained from pneumothorax surgery and positive immunohistochemical staining with HMB-45.
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http://dx.doi.org/10.1016/j.radcr.2022.02.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938872PMC
May 2022

Paragonimiasis diagnosed by CT-guided transthoracic lung biopsy: Literature review and case report.

Radiol Case Rep 2022 May 14;17(5):1591-1597. Epub 2022 Mar 14.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh, Vietnam.

More than 40 different species of the parasitic flatworm have been identified worldwide, including in Vietnam, but only 10 species are known to cause disease in humans, particularly are transmitted through the ingestion of raw foods, especially freshwater shrimp, and crab. Paragonimiasis causes pneumonia, which can present as acute or chronic, with symptoms including prolonged cough, chest pain, shortness of breath, and hemoptysis. Hematologic changes include eosinophilia and the presence of specific antibodies for in the blood. Diagnosis is confirmed when specimens or eggs are found in the sputum or pleural fluid. The specificity of imaging is not high, but imaging can be used to guide the diagnosis. After the failure of microbiological diagnostic methods, lung biopsy can be used to confirm a diagnosis of paragonimiasis. We present a paragonimiasis case associated with unique features, including epidemiologic factors, atypical clinical signs, no increases in blood eosinophils, and negative microbiological tests. Although the patient was suspected of tuberculosis or lung cancer, imaging studies were consistent with the presence of lung flukes. Three transthoracic lung biopsies were performed, and pathology revealed a cystic structure containing on the third biopsy.
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http://dx.doi.org/10.1016/j.radcr.2022.02.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927937PMC
May 2022

Mycotic Aneurysm with Iliac Artery-Colonic Fistula.

Case Rep Med 2022 4;2022:3250749. Epub 2022 Mar 4.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Although mycotic (infected) aneurysms are uncommon, they can affect any artery. The most frequently involved vessel is the aorta as well as femoral and cerebral arteries. A vascular-colonic fistula from infected aneurysms is even rarer, which remains a challenge for diagnosis and treatment. In this case report, we aimed to illustrate an 89-year-old man presenting initially with an aneurysm of the right common iliac artery. Forty days later, this lesion was infected and produced fresh blood in the rectum and sigmoid colon observed by colonoscopy. The final diagnosis of this case was a right common iliac artery aneurysm-colonic fistula due to infection. The patient was successfully diagnosed and treated with surgery at our hospital.
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http://dx.doi.org/10.1155/2022/3250749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916886PMC
March 2022

Multisystem Langerhans cell histiocytosis: Literature review and case report.

Radiol Case Rep 2022 May 2;17(5):1407-1412. Epub 2022 Mar 2.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh, Vietnam.

Langerhans cell histiocytosis (LCH) refers to a group of diseases of unknown etiology, typically discovered in childhood, characterized by the accumulation of Langerhans cells (white blood cells with large cell nuclei that may contain cytoplasmic histiocytosis X bodies) involving one or more organ systems, including bones, lungs, pituitary gland, skin, lymph nodes, and liver. This disease is also known as histiocytosis X or eosinophilic granuloma. Pulmonary LCH is common (identified in 40% of LCH patients) and may be isolated to the lung or involve other organs. Although LCH is characterized by clonal cell proliferation, adult LCH is considered likely to represent the manifestation of an aberrant immune response to an unspecified antigenic stimulus rather than a manifestation of tumor proliferation. We report a very complicated clinical case of LCH, with multiple organ damage that received a variety of different diagnoses. An LCH diagnosis was confirmed based on postoperative spinal cord pathology results and immunohistochemistry examinations. This case report highlights the clinical, laboratory, and imaging signs observed in this case that should be noted to help doctors more quickly recognize, diagnose, and treat similar cases.
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http://dx.doi.org/10.1016/j.radcr.2022.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891995PMC
May 2022

Gastric rupture following multiple blunt trauma.

Radiol Case Rep 2022 May 2;17(5):1380-1383. Epub 2022 Mar 2.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Gastric injury due to trauma is a rare complication that occurs in approximately 0.04%-1.2% of all instances of abdominal trauma. When imaging trauma cases, certain areas can be obscured by several inevitable reasons. Despite its rarity, the high mortality rate of a gastric injury requires an early and accurate diagnosis. We present the case of an 18-year-old male who suffered a gastric rupture of the greater curvature following a road traffic collision before providing a brief review of the literature.
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http://dx.doi.org/10.1016/j.radcr.2022.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892026PMC
May 2022

Intralobar pulmonary sequestration supplied by vessel from the inferior vena cava: Literature overview and case report.

Radiol Case Rep 2022 Apr 21;17(4):1345-1353. Epub 2022 Feb 21.

Department of Radiology, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Ward 12 District 10, Ho Chi Minh City, Vietnam.

Sequestration is a congenital abnormality that can occur in both children and adults. The clinical presentation often manifests as recurrent pneumonia throughout the lifetime of the patient. Pathologically, sequestration is a disorganized region of lung parenchyma without a normal pulmonary artery and with no interconnecting air passage (ie, it is isolated from the bronchi and pulmonary arteries). Sequestration can be either intralobar or extralobar and is usually supplied with blood from an anomalous vessel originating from the thoracic aorta or abdominal aorta (big circulation/systemic circulation), which is one of the mandatory criteria for diagnosing sequestration. CT angiography or catheter angiography can assist in identifying the anomalous vessel both for diagnosis and surgical resection. We present a rare case of intralobar sequestration with the distinction of being supplied with blood from the abdominal vena cava, as confirmed by CT angiography, surgery, and postoperative pathology. It is hoped that this study will contribute to the literature by introducing a rare case of congenital lung abnormality and pulmonary vascular malformation.
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http://dx.doi.org/10.1016/j.radcr.2022.01.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866838PMC
April 2022

Primary intraperitoneal solitary fibrous tumor in mesentery: How does it present?

Radiol Case Rep 2022 Apr 18;17(4):1318-1324. Epub 2022 Feb 18.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

Intra-abdominal solitary fibrous tumor (SFT), also known as hemangiopericytoma, is rare, especially for those with a mesenteric location, and only a few cases have been reported. Distinguishing a hemangiopericytoma from other intra-abdominal benign or malignant tumors can be difficult, as they have similar presentations on both computed tomography and magnetic resonance imaging. In the present study, the records for a 31-year-old Vietnamese woman who underwent abdominal surgery for greater omental tumor resection and received histopathological results revealing SFT are retrospectively reviewed. The case is discussed and similar reported cases are reviewed. Due to the aggressive behavior and high rate of postoperative recurrence associated with SFT, a thorough understanding of the radiologic and histopathological features of the disease is necessary to achieve an appropriate diagnosis and treatment.
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http://dx.doi.org/10.1016/j.radcr.2022.01.068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861309PMC
April 2022

Unilateral pulmonary vein atresia: Literature overview and case report.

Radiol Case Rep 2022 Apr 17;17(4):1313-1317. Epub 2022 Feb 17.

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

The unilateral absence of the pulmonary vein, known as pulmonary vein atresia, is a rare type of unilateral pulmonary venous hypoplasia caused by the congenital atrophy of the long pulmonary vein segments in one lung. The involved lung may be normal in size or present with hypoplasia and is often characterized by increased interstitial attenuation and interlobular septal thickening due to venous stasis, edema, and fibrosis. Pulmonary angiography often reveals a reduced size for the lateral pulmonary artery, peripherally sparse pulmonary vessels, contrast stasis, and the inability to visualize pulmonary veins. Symptoms include coughing up blood and infection. We present the clinical case of a patient who was initially diagnosed with recurrent hemoptysis due to pulmonary tuberculosis, followed by unsuccessful treatment. Imaging by 64-slice computed tomography with contrast injection using multiplanar reformation and volume rendering techniques allowed this case to be definitively diagnosed. This report emphasizes the epidemiological factors and clinical and imaging features of unilateral pulmonary vein atresia to prevent confusion and facilitate proper diagnosis in similar cases.
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http://dx.doi.org/10.1016/j.radcr.2022.01.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857560PMC
April 2022

Evaluation of Bite Force After Treatment of Le Fort Fractures by Internal Fixation and Mandibulomaxillary Fixation.

Med Arch 2021 Oct;75(5):371-374

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.

Objectives: Evaluation of bite force one, two, and four weeks after discharge following treatment of Le Fort I and/or Le Fort II fracture by rigid fixation and mandibulomaxillary fixation.

Objective: The aim of this study was to evaluate bite force following treatment of Le Fort I and/or Le Fort II fractures by rigid fixation and mandibulomaxillary fixation at one, two, and four weeks after discharge. This provides valuable results to guide the development of a treatment protocol for Le Fort fractures.

Method: This was a prospective study including 31 patients who underwent followup examination three times after being discharged from hospital. The examination evaluated bite force using a bite force meter in the right molar, left molar, and incisor regions.

Results: One week after discharge, bite forces in the right molar, left molar, and incisor regions were 94.29 ± 58.80 N, 95.42 ± 57.34 N, and 39,94 ± 30,29 N, respectively. Two weeks after discharge, bite forces in the right molar, left molar, and incisor regions were 153.84 ± 89.14 N, 153.00 ± 78.55 N, and 65,9 ± 43.89 N, respectively. Four weeks after discharge, bite forces in the right molar, left molar, and incisor regions were 279.77 ± 95.46 N, 285.00 ± 90,47 N, and 123.42 ± 54.04 N, respectively.

Conclusions: Bite forces in the right molar, left molar, and incisor regions were significantly increased one week, two weeks, and four weeks after discharge. Bite force may be a helpful parameter to confirm the stability of the midface bone after treatment of Le Fort fractures.
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http://dx.doi.org/10.5455/medarh.2021.75.371-374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740670PMC
October 2021

A Novel Approach to the Treatment of Le Fort Fractures Using Internal Fixation to Achieve Mandibulomaxillary Fixation.

Med Arch 2021 Oct;75(5):366-370

Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.

Background: We aimed to determine the minimum effective period of mandibulomaxillary fixation after the inadequate internal fixation of Le Fort I or Le Fort II fracture.

Objective: The aim of this study was to investigate the stability of the skeleton after the treatment of Le Fort I or Le Fort II fractures by measuring bite forces and to determine the minimum time required for effective mandibulomaxillary fixation following treatment with internal fixation and mandibulomaxillary fixation.

Method: A prospective study was performed to examine the treatment of Le Fort I or Le Fort II fracture in the Department of Maxillofacial Surgery at the National Hospital of Odonto-Stomatology in Ho Chi Minh City, Vietnam. A total of 31 patients were included, with up to 1 month of follow-up after discharge from the hospital. Midface bone stability and the mandibulomaxillary fixation time were evaluated using bite force criteria after 1, 2, and 4 weeks.

Results: Midface bone stability values 1, 2, and 4 weeks after treatment were 87.1%, 100%, and 100%, respectively. After 1 week, 87.1% of patients achieved intermaxillary fixation, and 96.3% of these patients were treated with at least three rigid plates. The remaining 12.9% of patients achieved fixation after 2 weeks, and all of these patients were fixed only at zygomaticomaxillary sutures (p < 0.05). Bite forces increased significantly at 2 weeks compared with 1 week and at 4 weeks compared with 2 weeks (p < 0.05).

Conclusion: When treated using only rigid fixation, through the placement of plates and screws at zygomaticomaxillary buttresses, patients with Le Fort I and Le Fort II fractures can achieve mandibulomaxillary fixation after 2 weeks. For Le Fort I fractures, rigid fixation using plates and screws at zygomaticomaxillary buttresses and canine buttress at three positions can achieve mandibulomaxillary fixation after only 1 week (p = 0.0001).
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http://dx.doi.org/10.5455/medarh.2021.75.366-370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740663PMC
October 2021

Pancreaticopleural fistula in children: Report of 2 cases.

Radiol Case Rep 2022 Mar 18;17(3):987-990. Epub 2022 Jan 18.

Department of Radiology, Children's Hospital 2, Ho Chi Minh City, Vietnam.

Pancreaticopleural fistula is an extremely rare complication of pancreatic duct injury. The reported treatments include conservative approaches, such as pleural drainage, and interventional approaches, such as sphincter stenting via endoscopic retrograde cholangiopancreatography and surgery. However, no specific consensus treatment has been defined. We present 2 cases of pediatric patients with pancreaticopleural fistulas due to pancreatic trauma and pancreatitis that were successfully treated surgically. The most prominent symptom in both cases was dyspnea caused by pleural effusion. Thoracoabdominal computed tomography scans showed large pleural effusions and visible fistulas from the pancreatic duct to the thoracic cavity through the esophageal hiatus and aortic hiatus. Following unsuccessful conservative treatment using pleural drainage, the 2 patients underwent surgical fistulo-jejunostomy and cystojejunostomy. Both patients were stable and were discharged on postoperative days 10 and 12. Conservative treatment for pancreaticopleural fistula often fails, and a surgical approach, such as fistulo-jejunostomy and cystojejunostomy, can serve as an efficacious management strategy when conservative treatment fails.
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http://dx.doi.org/10.1016/j.radcr.2022.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784284PMC
March 2022
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