Publications by authors named "Neven S Aref"

4 Publications

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Sesame Oil () as a New Challenge for Reinforcement of Conventional Glass Ionomer Cement, Could It Be?

Neven S Aref

Int J Dent 2021 22;2021:5516517. Epub 2021 Mar 22.

Department of Dental Biomaterials, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.

Purpose: Despite the advantages of glass ionomer cement (GIC) including chemical bonding to the tooth structure and fluoride release, its low-grade mechanical properties make it a topic for research. Accordingly, this study was conducted to assess the ability of sesame oil as a natural bioactive additive to reinforce conventional glass ionomer cement.

Materials And Methods: Sesame oil was blended into the liquid component of the cement in ratios of 3 and 5 (v/v%). One control and two experimental groups were enrolled in the study; I: unmodified GIC (control), II: 3 (v/v%) sesame oil-modified GICs, and III: 5(v/v%) sesame oil-modified GICs. Compressive strength, shear bond strength, diametral tensile strength, surface microhardness, surface roughness, and color stability were the parameters assessed. A representative specimen of each group was analyzed for its chemical structure by Fourier transformation infrared spectroscopy. One-way ANOVA followed by Tukey test was used to analyze the collected data of all evaluated parameters except the color stability results, which were analyzed by Student -test at < 0.05.

Results: Three and 5 (v/v%) sesame oil-modified GICs exhibited significant increase in their compressive strength, shear bond strength, diametral strength, and surface microhardness. Concurrently, there was a significant decrease in surface roughness ( < 0.05) in both formulations of the modified cement. Both 3 and 5 (v/v%) sesame oil-modified GICs showed a clinically acceptable color change.

Conclusions: Sesame oil seems to be a promising natural bioactive product for reinforcement of conventional GIC with a clinically agreeable esthetic.
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March 2021

An Assessment of Surface Roughness, Tensile Bond Strength and Antifungal Activity of Grape Seed Extract-modified Soft Liner.

Neven S Aref

J Contemp Dent Pract 2020 Apr 1;21(4):353-358. Epub 2020 Apr 1.

Dental Biomaterials Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt; Basic Oral and Medical Sciences Department, College of Dentistry, Qassim University, Buraydah, Kingdom of Saudi Arabia, Phone: +20 1003978955, e-mail:

Aim: This study was conducted to evaluate the grape seed extract (GSE)-modified soft liner regarding surface roughness, tensile bond strength to the denture base material, and the antifungal activity.

Materials And Methods: The GSE powder was blended with the soft liner powder in ratios of 5 and 10% w/w, and three groups were employed: I, control; II, 5% w/w GSE-modified soft liner; III, 10% w/w GSE-modified soft liner. Evaluation parameters included surface roughness, tensile bond strength to the denture base material, and the antifungal activity. Changes in surface topography were evaluated by scanning electron microscopy. The statistical analysis was performed using the one-way ANOVA followed by the Tukey's test (α = 0.05).

Results: The 5% w/w GSE-modified soft liner showed a significant increase in surface roughness, while both ratios (5 and 10% w/w) of the modified-soft liner exhibited significant increase in tensile bond strength and antifungal activity ( < 0.05).

Conclusion: The GSE of 10% w/w considerably enhanced the antifungal activity and tensile bond strength of the modified soft liner to the denture base material without compromising its surface roughness.

Clinical Significance: The 10% w/w GSE-modified soft liner may be a promising formulation with antifungal activity. It could inhibit fungal adherence and development of fungi-induced lesions or exacerbation of existing ones.
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April 2020

Does Modification of Amalgomer with Propolis Alter Its Physicomechanical Properties? An In Vitro Study.

Int J Biomater 2020 11;2020:3180879. Epub 2020 May 11.

Dental Biomaterials Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.

Objective: To assess if incorporating ethanolic extract of propolis into ceramic-reinforced glass ionomer (Amalgomer CR) might have an influence on its physicomechanical properties.

Materials And Methods: Three groups were assessed; group I: Amalgomer CR (control) and two experimental groups (II and III) of propolis added to the liquid of Amalgomer CR with 25 and 50 v/v %, respectively. Evaluation parameters were color stability, compressive strength, microhardness, and surface roughness. Representative specimens of each group were analyzed by Fourier-transform infrared spectroscopy, energy-dispersive X-ray, X-ray diffraction, and scanning electron microscopy. Analysis of variance (ANOVA) was used to compare the results, followed by a Tukey post hoc test ( < 0.05).

Results: Nonsignificant color change for both groups of modified Amalgomer CR. Meanwhile, the two experimental groups exhibited a significant increase in both compressive strength and microhardness. Simultaneously, there was a significant difference in roughness values among groups with the lowest roughness values exhibited by the 50 v/v % propolis concentration.

Conclusions: Modification of Amalgomer CR with 50 v/v % propolis may increase its mechanical properties without compromising its esthetic. . Modification of Amalgomer CR by 50 v/v % propolis is supposed to be a hopeful restorative material with favorable characteristics.
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May 2020

Resistance of resin-infiltrated enamel to surface changes in response to acidic challenge.

J Esthet Restor Dent 2019 07 20;31(4):353-358. Epub 2019 Mar 20.

Department of Orthodontics, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.

Objective: To investigate the ability of resin infiltration to protect demineralized enamel against acidic challenge.

Materials And Methods: Forty-five extracted healthy premolars were selected for the study, each of which was sectioned vertically into 2 halves, giving 90 specimens. Specimens were then divided into three groups, where specimens of group A were not decalcified (control), while those of groups B and C were either subjected to decalcification only, or decalcification followed by Icon resin infiltration, respectively. Each group was further divided into three subgroups, according to the type of storage medium (water, Coca-Cola, or Redbull). Evaluation parameters included color difference and surface roughness. Scanning electron microscope was used to evaluate enamel surface topography. Statistical analysis was performed by ANOVA followed by least significant difference test.

Results: Although Coca-Cola caused the highest color change and surface roughness among the studied specimens, yet, the resin-infiltrated enamel was more resistant to surface changes than the nonresin infiltrated enamel, even under acid attack.

Conclusion: Resin infiltration has the ability to provide and maintain protection to the demineralized enamel against acidic attack.

Clinical Significance: Resin infiltration may be considered as a promising solution to restore esthetic of demineralized enamel following orthodontic treatment and to protect it against acidic beverages.
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July 2019