Nerea Ferreiros

Nerea Ferreiros

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Nerea Ferreiros

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Implementation of lipidomics in clinical routine: Can fluoride/citrate blood sampling tubes improve preanalytical stability?

Talanta 2020 Mar 26;209:120593. Epub 2019 Nov 26.

Pharmazentrum Frankfurt/ ZAFES, Institute of Clinical Pharmacology, Goethe University, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2019.120593DOI Listing
March 2020

Tumors Provoke Inflammation and Perineural Microlesions at Adjacent Peripheral Nerves.

Cells 2020 Jan 29;9(2). Epub 2020 Jan 29.

Institute of Clinical Pharmacology, University Hospital Goethe University Frankfurt, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.3390/cells9020320DOI Listing
January 2020

A viral kinase counteracts in vivo restriction of murine cytomegalovirus by SAMHD1.

Nat Microbiol 2019 12 23;4(12):2273-2284. Epub 2019 Sep 23.

Institute of Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41564-019-0529-zDOI Listing
December 2019

Cytokine-induced endogenous production of prostaglandin D is essential for human group 2 innate lymphoid cell activation.

J Allergy Clin Immunol 2019 Jun 19;143(6):2202-2214.e5. Epub 2018 Dec 19.

Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.10.069DOI Listing
June 2019

Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.

Immunity 2019 05 23;50(5):1232-1248.e14. Epub 2019 Apr 23.

Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE, Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Sigmund-Freud-Str. 27, 53127 Bonn, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193013
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http://dx.doi.org/10.1016/j.immuni.2019.03.014DOI Listing
May 2019

Thromboxane-Induced α-CGRP Release from Peripheral Neurons Is an Essential Positive Feedback Loop in Capsaicin-Induced Neurogenic Inflammation.

J Invest Dermatol 2019 03 26;139(3):656-664. Epub 2018 Oct 26.

Institute of Clinical Pharmacology, Pharmazentrum Frankfurt, University Hospital Frankfurt, Germany; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine and Pharmacology, Frankfurt/Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.10.011DOI Listing
March 2019

Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes.

Sci Rep 2019 Jan 24;9(1):747. Epub 2019 Jan 24.

Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Branch for Translational Medicine and Pharmacology TMP, Theodor-Stern-Kai 7, 60596, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1038/s41598-018-37342-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345911PMC
January 2019

Simultaneous determination of PUFA-derived pro-resolving metabolites and pathway markers using chiral chromatography and tandem mass spectrometry.

Anal Chim Acta 2018 Nov 8;1031:185-194. Epub 2018 May 8.

pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University Frankfurt, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00032670183060
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http://dx.doi.org/10.1016/j.aca.2018.05.020DOI Listing
November 2018

The relevance of ceramides and their synthesizing enzymes for multiple sclerosis.

Clin Sci (Lond) 2018 09 17;132(17):1963-1976. Epub 2018 Aug 17.

Pharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany

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http://clinsci.org/lookup/doi/10.1042/CS20180506
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http://dx.doi.org/10.1042/CS20180506DOI Listing
September 2018

Mutual inversion of flurbiprofen enantiomers in various rat and mouse strains.

Chirality 2018 May 6;30(5):632-641. Epub 2018 Feb 6.

Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Research Center for Translational Medicine and Pharmacology TMP, Industriepark Höchst, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1002/chir.22826DOI Listing
May 2018

The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.

Mob DNA 2018 28;9:11. Epub 2018 Mar 28.

1Institute of Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nürnberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1186/s13100-018-0116-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872582PMC
March 2018

CD200 selectively upregulates prostaglandin E and D synthesis in LPS-treated bone marrow-derived macrophages.

Prostaglandins Other Lipid Mediat 2017 Nov 3;133:53-59. Epub 2017 Jun 3.

Institute of Clinical Pharmacology, pharmazentrum frankfurt/ZAFES, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10988823173001
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http://dx.doi.org/10.1016/j.prostaglandins.2017.06.002DOI Listing
November 2017

Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis.

Mol Immunol 2017 10 30;90:255-263. Epub 2017 Aug 30.

Institute of Biochemistry I - Pathobiochemistry, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine & Pharmacology TMP, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2017.08.011DOI Listing
October 2017

AMPK contributes to aerobic exercise-induced antinociception downstream of endocannabinoids.

Neuropharmacology 2017 Sep 4;124:134-142. Epub 2017 May 4.

Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2017.05.002DOI Listing
September 2017

Angiotensin II-AT1-receptor signaling is necessary for cyclooxygenase-2-dependent postnatal nephron generation.

Kidney Int 2017 04 28;91(4):818-829. Epub 2016 Dec 28.

Institute of Clinical Pharmacology, Johann Wolfgang Goethe-University, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.11.003DOI Listing
April 2017

GPVI and Thromboxane Receptor on Platelets Promote Proinflammatory Macrophage Phenotypes during Cutaneous Inflammation.

J Invest Dermatol 2017 03 3;137(3):686-695. Epub 2016 Nov 3.

Institut für Klinische Pharmakologie, pharmazentrum frankfurt, ZAFES, Klinikum der Goethe-Universität Frankfurt, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.09.036DOI Listing
March 2017

Epigenetic control of microsomal prostaglandin E synthase-1 by HDAC-mediated recruitment of p300.

J Lipid Res 2017 02 2;58(2):386-392. Epub 2016 Dec 2.

Institute for Cardiovascular Physiology, Medical Faculty, Goethe-University Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1194/jlr.M072280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282954PMC
February 2017

Microfluidic coagulation assay for monitoring anticoagulant therapy in acute stroke patients.

Thromb Haemost 2017 02 26;117(3):519-528. Epub 2017 Jan 26.

Oliver C. Singer, MD, Department of Neurology, HELIOS HSK Kliniken, Ludwig-Erhard-Str. 100, 65199 Wiesbaden, Germany, Tel.: +49 611 432376, Fax: +49 611 432732, E-mail:

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http://dx.doi.org/10.1160/TH16-08-0619DOI Listing
February 2017

Tetrahydrobiopterin Attenuates DSS-evoked Colitis in Mice by Rebalancing Redox and Lipid Signalling.

J Crohns Colitis 2016 Aug 29;10(8):965-78. Epub 2016 Feb 29.

Department of Clinical Pharmacology, Goethe-University Hospital Frankfurt, Germany

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http://dx.doi.org/10.1093/ecco-jcc/jjw056DOI Listing
August 2016

Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels.

Int J Mol Sci 2016 Jun 13;17(6). Epub 2016 Jun 13.

Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie, Goethe University Hospital, Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.3390/ijms17060922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926455PMC
June 2016

Activation-Induced Cell Death of Dendritic Cells Is Dependent on Sphingosine Kinase 1.

Front Pharmacol 2016 15;7:94. Epub 2016 Apr 15.

Department of General Pharmacology and Toxicology, Pharmazentrum Frankfurt/ZAFES, Clinic of the Goethe University Frankfurt, Germany.

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http://journal.frontiersin.org/Article/10.3389/fphar.2016.00
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http://dx.doi.org/10.3389/fphar.2016.00094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832589PMC
May 2016

Rhythmic control of endocannabinoids in the rat pineal gland.

Chronobiol Int 2015 10;32(6):869-74. Epub 2015 Jun 10.

Dr. Senckenbergische Anatomie, Institut für Anatomie II, Johann Wolfgang Goethe-Universität , Frankfurt am Main , Germany .

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http://dx.doi.org/10.3109/07420528.2015.1041596DOI Listing
April 2016

Sphingosine-1-phosphate receptor inhibition prevents denervation-induced dendritic atrophy.

Acta Neuropathol Commun 2016 Mar 31;4:28. Epub 2016 Mar 31.

Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe-University Frankfurt, Theodor-Stern-Kai 7, Frankfurt, 60590, Germany.

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http://dx.doi.org/10.1186/s40478-016-0303-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818430PMC
March 2016

Drug Release and Targeting: the Versatility of Polymethacrylate Nanoparticles for Peroral Administration Revealed by Using an Optimized In Vitro-Toolbox.

Pharm Res 2015 Dec 28;32(12):3986-98. Epub 2015 Jul 28.

Institute of Pharmaceutical Technology, Goethe University, Max-von-Laue-Str. 9, 60438, Frankfurt (Main), Germany.

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http://link.springer.com/10.1007/s11095-015-1759-2
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http://dx.doi.org/10.1007/s11095-015-1759-2DOI Listing
December 2015

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.

FASEB J 2015 Dec 19;29(12):5029-43. Epub 2015 Aug 19.

*Fraunhofer Institute for Molecular Biology and Applied Ecology, Project Group Translational Medicine and Pharmacology, Institute of Clinical Pharmacology, Pharmazentrum Frankfurt, and Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt, Germany; and Department of Medical Biochemistry and Biophysics, Division of Chemistry 2, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.1096/fj.15-275487DOI Listing
December 2015

AMP-activated protein kinase is activated by non-steroidal anti-inflammatory drugs.

Eur J Pharmacol 2015 Sep 3;762:299-305. Epub 2015 Jun 3.

Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.06.001DOI Listing
September 2015

Cardiovascular drug determination in bioanalysis: an update.

Bioanalysis 2015 Sep 23;7(18):2399-2417. Epub 2015 Sep 23.

Department of Analytical Chemistry, Faculty of Science & Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Basque Country, Spain.

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http://dx.doi.org/10.4155/bio.15.163DOI Listing
September 2015

COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex.

J Neurosci 2015 Aug;35(34):11791-810

Sorbonne Universités, UPMC Université Paris 06, Institut de Biologie Paris-Seine (IBPS), UM 119, Neuroscience Paris Seine, F-75005, Paris, France, CNRS, UMR 8246, Neuroscience Paris Seine, F-75005, Paris, France, INSERM, UMR-S 1130, Neuroscience Paris Seine, F-75005, Paris, France,

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http://dx.doi.org/10.1523/JNEUROSCI.0651-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705452PMC
August 2015

Lack of ceramide synthase 2 suppresses the development of experimental autoimmune encephalomyelitis by impairing the migratory capacity of neutrophils.

Brain Behav Immun 2015 May 16;46:280-92. Epub 2015 Feb 16.

Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2015.02.010DOI Listing
May 2015

Identification and characterisation of a prototype for a new class of competitive PPARγ antagonists.

Eur J Pharmacol 2015 May 5;755:16-26. Epub 2015 Mar 5.

Institute of Biochemistry I - Pathobiochemistry, Faculty of Medicine, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.02.034DOI Listing
May 2015

Quantitation of endogenous nucleoside triphosphates and nucleosides in human cells by liquid chromatography tandem mass spectrometry.

Anal Bioanal Chem 2015 May 8;407(13):3693-704. Epub 2015 Mar 8.

pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00216-015-8588-3DOI Listing
May 2015

Variations in serum sphingolipid levels associate with liver fibrosis progression and poor treatment outcome in hepatitis C virus but not hepatitis B virus infection.

Hepatology 2015 Mar 28;61(3):812-22. Epub 2015 Jan 28.

Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Frankfurt am Main, Germany; Goethe University Hospital, Medizinische Klinik 1, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1002/hep.27587DOI Listing
March 2015

Telaprevir drug monitoring during antiviral therapy of hepatitis C graft infection after liver transplantation.

Liver Int 2015 Jan 9;35(1):176-83. Epub 2014 Apr 9.

Medizinische Klinik 1, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, Frankfurt, 60590, Germany.

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http://dx.doi.org/10.1111/liv.12532DOI Listing
January 2015

Regulation of circulating endocannabinoids associated with cancer and metastases in mice and humans.

Oncoscience 2014 30;1(4):272-282. Epub 2014 Apr 30.

pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University Hospital, Frankfurt am Main, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278301PMC
http://dx.doi.org/10.18632/oncoscience.33DOI Listing
January 2015

Role of telaprevir plasma levels for predicting response to antiviral therapy in patients with hepatitis C virus genotype 1 infection.

Scand J Gastroenterol 2014 Dec 11;49(12):1473-9. Epub 2014 Nov 11.

Medizinische Klinik 1, Universitätsklinikum Frankfurt , Theodor-Stern-Kai 7, 60590 Frankfurt am Main , Germany.

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http://dx.doi.org/10.3109/00365521.2014.978363DOI Listing
December 2014

Ceramide synthases CerS4 and CerS5 are upregulated by 17β-estradiol and GPER1 via AP-1 in human breast cancer cells.

Biochem Pharmacol 2014 Dec 22;92(4):577-89. Epub 2014 Oct 22.

pharmazentrum frankfurt/ZAFES, Institute for Clinical Pharmacology, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952140059
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http://dx.doi.org/10.1016/j.bcp.2014.10.007DOI Listing
December 2014

Regulation of ceramide synthase 6 in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent.

Biochem Pharmacol 2014 Nov 27;92(2):326-35. Epub 2014 Aug 27.

pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952140048
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http://dx.doi.org/10.1016/j.bcp.2014.08.016DOI Listing
November 2014

R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice.

EMBO Mol Med 2014 Nov;6(11):1398-422

Institute of Clinical Pharmacology Goethe-University Hospital, Frankfurt am Main, Germany Fraunhofer Institute of Molecular Biology and Applied Ecology Project Group Translational Medicine and Pharmacology (IME-TMP), Frankfurt am Main, Germany

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http://dx.doi.org/10.15252/emmm.201404168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237468PMC
November 2014

Lipoxin A₄: problems with its determination using reversed phase chromatography-tandem mass spectrometry and confirmation with chiral chromatography.

Talanta 2014 Sep 29;127:82-7. Epub 2014 Mar 29.

pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University, Frankfurt, Germany; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine and Pharmacology (TMP), Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.talanta.2014.03.051DOI Listing
September 2014

Chiral chromatography-tandem mass spectrometry applied to the determination of pro-resolving lipid mediators.

J Chromatogr A 2014 Sep 29;1360:150-63. Epub 2014 Jul 29.

pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2014.07.068DOI Listing
September 2014

Phosphodiesterase 2A localized in the spinal cord contributes to inflammatory pain processing.

Anesthesiology 2014 Aug;121(2):372-82

From the Pharmazentrum Frankfurt/Zentrum für Arzneimittelforschung, -entwicklung und -sicherheit, Institut für Klinische Pharmakologie, Universitätsklinikum Frankfurt, Frankfurt am Main, Germany (W.K-.G., R.L., A.B., D.T., J.E.L., N.L., N.F., G.G., A.S.); Institut für Pharmakologie und Toxikologie, Zentrum für Biomedizinische Ausbildung und Forschung, Universität Witten/Herdecke, Witten, Germany (R.L., C.I.R., A.S.); and Institut für Klinische Neuroanatomie, Neuroscience Center, Goethe-Universität, Frankfurt am Main, Germany (J.S., D.D.T.). Current address: Institut für Neuroradiologie, Universitätsklinikum Frankfurt, Frankfurt am Main, Germany (A.B.).

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http://dx.doi.org/10.1097/ALN.0000000000000270DOI Listing
August 2014

Hypoxia-inducible factor 1 regulates heat and cold pain sensitivity and persistence.

Antioxid Redox Signal 2014 Jun 30;20(16):2555-71. Epub 2014 Jan 30.

1 Pharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University Hospital Frankfurt , Frankfurt, Germany .

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http://dx.doi.org/10.1089/ars.2013.5494DOI Listing
June 2014

Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses.

Diabetologia 2014 May 1;57(5):1067-77. Epub 2014 Feb 1.

Faculty of Medicine, Institute of Biochemistry I/ZAFES, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00125-014-3173-4DOI Listing
May 2014

Prostacyclin mediates neuropathic pain through interleukin 1β-expressing resident macrophages.

Pain 2014 Mar 11;155(3):545-55. Epub 2013 Dec 11.

Institute of Clinical Pharmacology, Pharmazentrum Frankfurt/ZAFES, Hospital of the Goethe-University, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pain.2013.12.006DOI Listing
March 2014

Intranasal sufentanil/ketamine analgesia in children.

Paediatr Anaesth 2014 Feb 1;24(2):170-80. Epub 2013 Oct 1.

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Paediatric Pain Service, Department of Anaesthesiology, The Juliane Marie Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/pan.12268DOI Listing
February 2014

PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis.

Biochem Pharmacol 2014 Feb 16;87(4):625-35. Epub 2013 Dec 16.

pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine and Pharmacology (TMP), Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.bcp.2013.12.006DOI Listing
February 2014

Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1.

Bioorg Med Chem 2013 Dec 16;21(24):7874-83. Epub 2013 Oct 16.

Institute of Pharmaceutical Chemistry, Goethe-University Frankfurt, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.bmc.2013.10.006DOI Listing
December 2013

Recent advances in LC-MS/MS analysis of Δ(9)-tetrahydrocannabinol and its metabolites in biological matrices.

Authors:
Nerea Ferreirós

Bioanalysis 2013 Nov;5(21):2713-31

pharmazentrum grankfurt/ZAFES, Institute of Clinical Pharmacology, Uniklinik der J. W. Goethe Universität, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.4155/bio.13.218DOI Listing
November 2013

Exogenous delta⁹-tetrahydrocannabinol influences circulating endogenous cannabinoids in humans.

J Clin Psychopharmacol 2013 Oct;33(5):699-705

Institute of Clinical Pharmacology, Goethe-University, Frankfurt am Main, Germany.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/JCP.0b013e3182984015DOI Listing
October 2013

Pharmacokinetics of intraluminally administered serum papaverine for spasm prophylaxis of the internal mammary artery.

Heart Surg Forum 2013 Oct;16(5):E266-70

Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt am Main.

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http://dx.doi.org/10.1532/HSF98.2013201DOI Listing
October 2013

Anandamide deficiency and heightened neuropathic pain in aged mice.

Neuropharmacology 2013 Aug 15;71:204-15. Epub 2013 Apr 15.

Pharmazentrum Frankfurt, Institute of Clinical Pharmacology, Goethe-University Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.neuropharm.2013.03.021DOI Listing
August 2013

Ceramide metabolism in mouse tissue.

Int J Biochem Cell Biol 2013 Aug 19;45(8):1886-94. Epub 2013 Jun 19.

Pharmazentrum Frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Frankfurt/Main 60590, Germany.

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http://dx.doi.org/10.1016/j.biocel.2013.06.004DOI Listing
August 2013

The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.

Int J Biochem Cell Biol 2013 Jul 26;45(7):1195-203. Epub 2013 Mar 26.

Pharmazentrum Frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.

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http://dx.doi.org/10.1016/j.biocel.2013.03.012DOI Listing
July 2013

Heterologously expressed formyl peptide receptor 2 (FPR2/ALX) does not respond to lipoxin A₄.

Biochem Pharmacol 2013 Jun 1;85(12):1795-802. Epub 2013 May 1.

Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.bcp.2013.04.019DOI Listing
June 2013

Inhibition of GTP cyclohydrolase reduces cancer pain in mice and enhances analgesic effects of morphine.

J Mol Med (Berl) 2012 Dec 17;90(12):1473-86. Epub 2012 Jun 17.

pharmazentrum frankfurt, ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor Stern Kai 7, Hs 74, 60590 Frankfurt, Germany.

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http://link.springer.com/10.1007/s00109-012-0927-7
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http://dx.doi.org/10.1007/s00109-012-0927-7DOI Listing
December 2012

Genetic-epigenetic interaction modulates μ-opioid receptor regulation.

Hum Mol Genet 2012 Nov 8;21(21):4751-60. Epub 2012 Aug 8.

Institute of Clinical Pharmacology, Goethe-University, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1093/hmg/dds314DOI Listing
November 2012

Necessity and risks of arterial blood sampling in healthy volunteer studies.

Clin Pharmacokinet 2012 Oct;51(10):629-38

pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, J. W. Goethe-University Hospital, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s40262-012-0001-1DOI Listing
October 2012

Ceramide synthase 6 plays a critical role in the development of experimental autoimmune encephalomyelitis.

J Immunol 2012 Jun 27;188(11):5723-33. Epub 2012 Apr 27.

Pharmazentrum Frankfurt, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, 60590 Frankfurt/Main, Germany.

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http://dx.doi.org/10.4049/jimmunol.1103109DOI Listing
June 2012

Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth.

Int J Biochem Cell Biol 2012 Apr 2;44(4):620-8. Epub 2012 Jan 2.

Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.

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http://dx.doi.org/10.1016/j.biocel.2011.12.019DOI Listing
April 2012

Inhibitors of specific ceramide synthases.

Biochimie 2012 Feb 17;94(2):558-65. Epub 2011 Sep 17.

Pharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.

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http://dx.doi.org/10.1016/j.biochi.2011.09.007DOI Listing
February 2012

The protein kinase IKKε is a potential target for the treatment of inflammatory hyperalgesia.

J Immunol 2011 Sep 3;187(5):2617-25. Epub 2011 Aug 3.

Pharmazentrum Frankfurt/Das Zentrum für Arzneimittelforschung, Entwicklung und -Sicherheit, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.4049/jimmunol.1004088DOI Listing
September 2011

Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator.

Biochem Pharmacol 2011 Mar 14;81(5):617-25. Epub 2010 Dec 14.

Institut für Pharmakologie, Universitätsklinikum Essen, Germany.

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http://dx.doi.org/10.1016/j.bcp.2010.12.002DOI Listing
March 2011

Development of an LC-MS/MS method for the quantitation of 55 compounds prescribed in combined cardiovascular therapy.

J Chromatogr B Analyt Technol Biomed Life Sci 2011 Feb 15;879(3-4):243-52. Epub 2010 Dec 15.

Analytical Chemistry Department, Science and Technology Faculty Leioa, Spain.

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http://dx.doi.org/10.1016/j.jchromb.2010.12.007DOI Listing
February 2011

LC-MS/MS method for the determination of several drugs used in combined cardiovascular therapy in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Oct 6;878(28):2685-92. Epub 2010 Aug 6.

Analytical Chemistry Department, Science and Technology Faculty, Basque Country University/EHU, P.O. Box 644, 48080 Bilbao, Basque Country, Spain.

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http://dx.doi.org/10.1016/j.jchromb.2010.07.026DOI Listing
October 2010

Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds.

J Mass Spectrom 2010 Oct;45(10):1186-94

Institute of Forensic Medicine, Forensic Toxicology, University Medical Center Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/jms.1811DOI Listing
October 2010

Validation of a fast liquid chromatography-UV method for the analysis of drugs used in combined cardiovascular therapy in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2009 Oct 19;877(27):3045-53. Epub 2009 Jul 19.

Pintura Saila, Arte Ederretako Fakultatea, Euskal Herriko Unibertsitatea/UPV, P.K. 644, 48080 Bilbo, Basque Country, Spain.

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http://dx.doi.org/10.1016/j.jchromb.2009.07.018DOI Listing
October 2009

Fatal and severe codeine intoxication in 3-year-old twins--interpretation of drug and metabolite concentrations.

Int J Legal Med 2009 Sep 7;123(5):387-94. Epub 2009 Apr 7.

Institute of Forensic Medicine, Freiburg University Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00414-009-0340-0DOI Listing
September 2009