Nelson L S Tang

Nelson L S Tang

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Nelson L S Tang

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The association of liver function and quality of life of patients with liver cancer.

BMC Gastroenterol 2019 May 2;19(1):66. Epub 2019 May 2.

Department of Clinical Oncology, Prince of Wales Hospital, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR.

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http://dx.doi.org/10.1186/s12876-019-0984-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498612PMC
May 2019

Correlations of health-related quality of life with serum inflammatory indicators IL-8 and mIBI in patients with hepatocellular carcinoma.

Cancer Manag Res 2019 4;11:2719-2727. Epub 2019 Apr 4.

Department of Clinical Oncology, Prince of Wales Hospital, Faculty of Medicine, Hong Kong Cancer Institute, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong SAR,

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http://dx.doi.org/10.2147/CMAR.S178482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452825PMC
April 2019

Discovering Genetic Factors for psoriasis through exhaustively searching for significant second order SNP-SNP interactions.

Sci Rep 2018 Oct 12;8(1):15186. Epub 2018 Oct 12.

Department of Computer Science and Engineering, the Chinese University of Hong Kong, Hong Kong, China.

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http://www.nature.com/articles/s41598-018-33493-w
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http://dx.doi.org/10.1038/s41598-018-33493-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185942PMC
October 2018

Profiles of lipids, blood pressure and weight changes among premenopausal Chinese breast cancer patients after adjuvant chemotherapy.

BMC Womens Health 2017 07 27;17(1):55. Epub 2017 Jul 27.

Department of Clinical Oncology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR.

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http://dx.doi.org/10.1186/s12905-017-0409-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532788PMC
July 2017

The mechanism of transactivation regulation due to polymorphic short tandem repeats (STRs) using IGF1 promoter as a model.

Sci Rep 2016 12 2;6:38225. Epub 2016 Dec 2.

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.

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http://dx.doi.org/10.1038/srep38225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133613PMC
December 2016

Chemotherapy-Related Amenorrhea and Menopause in Young Chinese Breast Cancer Patients: Analysis on Incidence, Risk Factors and Serum Hormone Profiles.

PLoS One 2015 20;10(10):e0140842. Epub 2015 Oct 20.

Department of Clinical Oncology and Comprehensive Cancer Trials Unit, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140842PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613138PMC
June 2016

AGTR1 has undergone natural selection in Euro-Asian populations in relation to ambient temperature that predisposes Chinese populations to essential hypertension.

Int J Cardiol 2016 Apr 5;209:278-80. Epub 2016 Feb 5.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China; Department of Preventive Medicine, School of Medicine, Ningbo University, Ningbo, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.02.031DOI Listing
April 2016

CrossNorm: a novel normalization strategy for microarray data in cancers.

Sci Rep 2016 Jan 6;6:18898. Epub 2016 Jan 6.

Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.

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http://dx.doi.org/10.1038/srep18898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702063PMC
January 2016

A network based covariance test for detecting multivariate eQTL in saccharomyces cerevisiae.

BMC Syst Biol 2016 Jan 11;10 Suppl 1. Epub 2016 Jan 11.

LMAM, School of Mathematical Sciences, Peking University, Yiheyuan Road, Beijing, 100871, China.

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http://dx.doi.org/10.1186/s12918-015-0245-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895706PMC
January 2016

Gender difference of serum angiotensin-converting enzyme (ACE) activity in DD genotype of ACE insertion/deletion polymorphism in elderly Chinese.

J Renin Angiotensin Aldosterone Syst 2014 Dec 6;15(4):547-52. Epub 2013 Feb 6.

Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, PR China

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http://dx.doi.org/10.1177/1470320313475906DOI Listing
December 2014

Exome sequencing identifies a rare HSPG2 variant associated with familial idiopathic scoliosis.

G3 (Bethesda) 2014 Dec 12;5(2):167-74. Epub 2014 Dec 12.

Department of Orthopedics, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, 80045 Musculoskeletal Research Center, Children's Hospital Colorado, Aurora, Colorado, 80045

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http://dx.doi.org/10.1534/g3.114.015669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321025PMC
December 2014

Molecular evolution in the CREB1 signal pathway and a rare haplotype in CREB1 with genetic predisposition to schizophrenia.

J Psychiatr Res 2014 Oct 24;57:84-9. Epub 2014 Jun 24.

Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan 650201, China; KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, Yunnan, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2014.06.008DOI Listing
October 2014

Inherited metabolic diseases in the Southern Chinese population: spectrum of diseases and estimated incidence from recurrent mutations.

Pathology 2014 Aug;46(5):375-82

1Department of Pediatrics, and 2Joint Metabolic Clinic, Prince of Wales Hospital, Hong Kong 3Department of Chemical Pathology, and 4Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong 5Shenzhen Research Institute, Chinese University of Hong Kong, Shenzhen 6Department of Anatomical and Cellular Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong 7Department of Dietetics, Prince of Wales Hospital, Hong Kong 8Department of Paediatrics and Adolescent Medicine, Alice Ho Miu Ling Nethersole Hospital, Hong Kong, China *these authors contributed equally.

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https://linkinghub.elsevier.com/retrieve/pii/S00313025163055
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http://dx.doi.org/10.1097/PAT.0000000000000140DOI Listing
August 2014

The predisposition to thyrotoxic periodic paralysis (TPP) is due to a genetic variant in the inward-rectifying potassium channel, KCNJ2.

Clin Endocrinol (Oxf) 2014 May 31;80(5):770-1. Epub 2013 Jul 31.

Department of Chemical Pathology, The Chinese University of Hong Kong, N.T., Hong Kong SAR; Functional Genomics and Biostatistical Computing Laboratory, Shenzhen Research Institute of the Chinese University of Hong Kong.

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http://dx.doi.org/10.1111/cen.12277DOI Listing
May 2014

Functional interaction between SNPs and microsatellite in the transcriptional regulation of insulin-like growth factor 1.

Hum Mutat 2013 Sep 8;34(9):1289-97. Epub 2013 Jul 8.

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/humu.22363DOI Listing
September 2013

Telomere length and cognitive function in southern Chinese community-dwelling male elders.

Age Ageing 2013 Jul 21;42(4):450-5. Epub 2013 Mar 21.

Psychiatry, The Chinese University of Hong Kong, G/F, Multi-Centre, Tai Po Hospital Chuen On Road, Tai Po, NT Hong Kong SAR, The People's Republic of China.

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http://dx.doi.org/10.1093/ageing/aft036DOI Listing
July 2013

The role of the Ala746Thr variant in the ATP13A2 gene among Chinese patients with Parkinson's disease.

J Clin Neurosci 2013 May 20;20(5):761-2. Epub 2013 Mar 20.

Division of Neurology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1016/j.jocn.2012.05.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209840PMC
May 2013

Lack of association between polymorphisms from genome-wide association studies and tuberculosis in the Chinese population.

Scand J Infect Dis 2013 Apr 31;45(4):310-4. Epub 2012 Oct 31.

Department of Biochemistry, School of Medicine, Ningbo University, Ningbo, China.

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http://dx.doi.org/10.3109/00365548.2012.726739DOI Listing
April 2013

Role of pharmacogenetics on adjuvant chemotherapy-induced neutropenia in Chinese breast cancer patients.

J Cancer Res Clin Oncol 2013 Mar 10;139(3):419-27. Epub 2012 Nov 10.

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.

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http://link.springer.com/10.1007/s00432-012-1345-5
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http://dx.doi.org/10.1007/s00432-012-1345-5DOI Listing
March 2013

Genetic adaptation of the hypoxia-inducible factor pathway to oxygen pressure among eurasian human populations.

Mol Biol Evol 2012 Nov 23;29(11):3359-70. Epub 2012 May 23.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.

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http://dx.doi.org/10.1093/molbev/mss144DOI Listing
November 2012

MxA polymorphisms are associated with risk and age-at-onset in Alzheimer disease and accelerated cognitive decline in Chinese elders.

Rejuvenation Res 2012 Oct 21;15(5):516-22. Epub 2012 Sep 21.

Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong .

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http://dx.doi.org/10.1089/rej.2012.1328DOI Listing
October 2012

Genetic epidemiology and heritability of AIS: A study of 415 Chinese female patients.

J Orthop Res 2012 Sep 23;30(9):1464-9. Epub 2012 Feb 23.

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/jor.22090DOI Listing
September 2012

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Authors:
Karol Estrada Unnur Styrkarsdottir Evangelos Evangelou Yi-Hsiang Hsu Emma L Duncan Evangelia E Ntzani Ling Oei Omar M E Albagha Najaf Amin John P Kemp Daniel L Koller Guo Li Ching-Ti Liu Ryan L Minster Alireza Moayyeri Liesbeth Vandenput Dana Willner Su-Mei Xiao Laura M Yerges-Armstrong Hou-Feng Zheng Nerea Alonso Joel Eriksson Candace M Kammerer Stephen K Kaptoge Paul J Leo Gudmar Thorleifsson Scott G Wilson James F Wilson Ville Aalto Markku Alen Aaron K Aragaki Thor Aspelund Jacqueline R Center Zoe Dailiana David J Duggan Melissa Garcia Natàlia Garcia-Giralt Sylvie Giroux Göran Hallmans Lynne J Hocking Lise Bjerre Husted Karen A Jameson Rita Khusainova Ghi Su Kim Charles Kooperberg Theodora Koromila Marcin Kruk Marika Laaksonen Andrea Z Lacroix Seung Hun Lee Ping C Leung Joshua R Lewis Laura Masi Simona Mencej-Bedrac Tuan V Nguyen Xavier Nogues Millan S Patel Janez Prezelj Lynda M Rose Serena Scollen Kristin Siggeirsdottir Albert V Smith Olle Svensson Stella Trompet Olivia Trummer Natasja M van Schoor Jean Woo Kun Zhu Susana Balcells Maria Luisa Brandi Brendan M Buckley Sulin Cheng Claus Christiansen Cyrus Cooper George Dedoussis Ian Ford Morten Frost David Goltzman Jesús González-Macías Mika Kähönen Magnus Karlsson Elza Khusnutdinova Jung-Min Koh Panagoula Kollia Bente Lomholt Langdahl William D Leslie Paul Lips Östen Ljunggren Roman S Lorenc Janja Marc Dan Mellström Barbara Obermayer-Pietsch José M Olmos Ulrika Pettersson-Kymmer David M Reid José A Riancho Paul M Ridker François Rousseau P Eline Slagboom Nelson L S Tang Roser Urreizti Wim Van Hul Jorma Viikari María T Zarrabeitia Yurii S Aulchenko Martha Castano-Betancourt Elin Grundberg Lizbeth Herrera Thorvaldur Ingvarsson Hrefna Johannsdottir Tony Kwan Rui Li Robert Luben Carolina Medina-Gómez Stefan Th Palsson Sjur Reppe Jerome I Rotter Gunnar Sigurdsson Joyce B J van Meurs Dominique Verlaan Frances M K Williams Andrew R Wood Yanhua Zhou Kaare M Gautvik Tomi Pastinen Soumya Raychaudhuri Jane A Cauley Daniel I Chasman Graeme R Clark Steven R Cummings Patrick Danoy Elaine M Dennison Richard Eastell John A Eisman Vilmundur Gudnason Albert Hofman Rebecca D Jackson Graeme Jones J Wouter Jukema Kay-Tee Khaw Terho Lehtimäki Yongmei Liu Mattias Lorentzon Eugene McCloskey Braxton D Mitchell Kannabiran Nandakumar Geoffrey C Nicholson Ben A Oostra Munro Peacock Huibert A P Pols Richard L Prince Olli Raitakari Ian R Reid John Robbins Philip N Sambrook Pak Chung Sham Alan R Shuldiner Frances A Tylavsky Cornelia M van Duijn Nick J Wareham L Adrienne Cupples Michael J Econs David M Evans Tamara B Harris Annie Wai Chee Kung Bruce M Psaty Jonathan Reeve Timothy D Spector Elizabeth A Streeten M Carola Zillikens Unnur Thorsteinsdottir Claes Ohlsson David Karasik J Brent Richards Matthew A Brown Kari Stefansson André G Uitterlinden Stuart H Ralston John P A Ioannidis Douglas P Kiel Fernando Rivadeneira

Nat Genet 2012 Apr 15;44(5):491-501. Epub 2012 Apr 15.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://kooperberg.fhcrc.org/papers/2012estrada.pdf
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http://www.nature.com/doifinder/10.1038/ng.2249
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http://dx.doi.org/10.1038/ng.2249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338864PMC
April 2012

Familial aggregation of narcolepsy.

Sleep Med 2011 Dec 28;12(10):947-51. Epub 2011 Oct 28.

Department of Psychiatry, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1016/j.sleep.2011.05.007DOI Listing
December 2011

A hidden two-locus disease association pattern in genome-wide association studies.

BMC Bioinformatics 2011 May 14;12:156. Epub 2011 May 14.

Department of Electronic and Computer Engineering, Hong Kong University of Science and Technology, Hong Kong.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-12-156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116488PMC
May 2011

Haplotype effect in the IGF1 promoter accounts for the association between microsatellite and serum IGF1 concentration.

Clin Endocrinol (Oxf) 2011 Apr;74(4):520-7

Department of Chemical Pathology, Faculty of Medicine School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.

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http://doi.wiley.com/10.1111/j.1365-2265.2010.03962.x
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http://dx.doi.org/10.1111/j.1365-2265.2010.03962.xDOI Listing
April 2011

Novel mutations in PHKA2 gene in glycogen storage disease type IX patients from Hong Kong, China.

Mol Genet Metab 2011 Feb 23;102(2):222-5. Epub 2010 Nov 23.

School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1016/j.ymgme.2010.11.004DOI Listing
February 2011

Shorter telomere length is associated with greater decrease in ankle-brachial index in elderly Chinese women but not men.

Angiology 2011 Jan 26;62(1):87-91. Epub 2010 May 26.

Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1177/0003319710371618DOI Listing
January 2011

Association of SRD5A2 variants and serum androstane-3alpha,17beta-diol glucuronide concentration in Chinese elderly men.

Clin Chem 2010 Nov 20;56(11):1742-9. Epub 2010 Sep 20.

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1373/clinchem.2010.150607DOI Listing
November 2010

Detecting two-locus associations allowing for interactions in genome-wide association studies.

Bioinformatics 2010 Oct 24;26(20):2517-25. Epub 2010 Aug 24.

Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology, Hong Kong, China.

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http://dx.doi.org/10.1093/bioinformatics/btq486DOI Listing
October 2010

PHF11 is not a major candidate gene for asthma or eczema in Chinese children.

Pediatr Pulmonol 2010 Sep;45(9):890-7

Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

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http://dx.doi.org/10.1002/ppul.21242DOI Listing
September 2010

BOOST: A fast approach to detecting gene-gene interactions in genome-wide case-control studies.

Am J Hum Genet 2010 Sep;87(3):325-40

Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology, China.

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http://linkinghub.elsevier.com/retrieve/pii/S000292971000378
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http://dx.doi.org/10.1016/j.ajhg.2010.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933337PMC
September 2010

Lack of association between the promoter polymorphisms of MMP-3 and IL-6 genes and adolescent idiopathic scoliosis: a case-control study in a Chinese Han population.

Spine (Phila Pa 1976) 2010 Aug;35(18):1701-5

Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.

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http://dx.doi.org/10.1097/BRS.0b013e3181c6ba13DOI Listing
August 2010

Association of plasma soluble CTLA-4 with lung function and gene polymorphism in Chinese asthmatic children.

Int Arch Allergy Immunol 2010 16;152(2):113-21. Epub 2009 Dec 16.

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, SAR, China.

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http://search.proquest.com/openview/640ce2684d28531ba9aa4a83
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http://www.karger.com/doi/10.1159/000265532
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http://dx.doi.org/10.1159/000265532DOI Listing
June 2010

Association of disease-predisposition polymorphisms of the melatonin receptors and sunshine duration in the global human populations.

J Pineal Res 2010 Mar 30;48(2):133-41. Epub 2009 Dec 30.

Department of Biochemistry and Genetics, School of Medicine, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.1111/j.1600-079X.2009.00736.xDOI Listing
March 2010

Sex-specific effect of Pirin gene on bone mineral density in a cohort of 4000 Chinese.

Bone 2010 Feb 18;46(2):543-50. Epub 2009 Sep 18.

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.bone.2009.09.012DOI Listing
February 2010

High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults.

Clin Chim Acta 2010 Jan 12;411(1-2):67-71. Epub 2009 Oct 12.

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

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http://dx.doi.org/10.1016/j.cca.2009.10.005DOI Listing
January 2010

Predictive rule inference for epistatic interaction detection in genome-wide association studies.

Bioinformatics 2010 Jan 30;26(1):30-7. Epub 2009 Oct 30.

Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology, Hong Kong, China.

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http://dx.doi.org/10.1093/bioinformatics/btp622DOI Listing
January 2010

Polymorphisms of the estrogen receptor alpha (ESR1) gene and the risk of Alzheimer's disease in a southern Chinese community.

Int Psychogeriatr 2009 Oct 9;21(5):977-86. Epub 2009 Jul 9.

Department of Chemical Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.

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http://dx.doi.org/10.1017/S1041610209990068DOI Listing
October 2009

Older men with higher self-rated socioeconomic status have shorter telomeres.

Age Ageing 2009 Sep 25;38(5):553-8. Epub 2009 Jun 25.

Department of Medicine & Therapeutics, The Chinese University of Hong Kong, 9/F, Prince of Wales Hospital, Shatin, N.T., Hong Kong.

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http://dx.doi.org/10.1093/ageing/afp098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729241PMC
September 2009

Novel mutations in ETFDH gene in Chinese patients with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.

Clin Chim Acta 2009 Jun 3;404(2):95-9. Epub 2009 Mar 3.

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong.

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http://dx.doi.org/10.1016/j.cca.2009.02.015DOI Listing
June 2009

Promoter polymorphism of matrilin-1 gene predisposes to adolescent idiopathic scoliosis in a Chinese population.

Eur J Hum Genet 2009 Apr 5;17(4):525-32. Epub 2008 Nov 5.

Spine Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.

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http://www.nature.com/articles/ejhg2008203
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http://dx.doi.org/10.1038/ejhg.2008.203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2986210PMC
April 2009

Interindividual and interethnic variation in genomewide gene expression: insights into the biological variation of gene expression and clinical implications.

Clin Chem 2009 Apr 20;55(4):774-85. Epub 2009 Feb 20.

Departments of Chemical Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.

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http://www.clinchem.org/cgi/doi/10.1373/clinchem.2008.119107
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http://dx.doi.org/10.1373/clinchem.2008.119107DOI Listing
April 2009

Association of early growth response-1 gene polymorphisms with total IgE and atopy in asthmatic children.

Pediatr Allergy Immunol 2009 Mar 28;20(2):142-50. Epub 2008 May 28.

Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/j.1399-3038.2008.00757.xDOI Listing
March 2009

MegaSNPHunter: a learning approach to detect disease predisposition SNPs and high level interactions in genome wide association study.

BMC Bioinformatics 2009 Jan 9;10:13. Epub 2009 Jan 9.

Department of Electronic and Computer Engineering, Hong Kong University of Science and Technology, Hong Kong, PR China.

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http://dx.doi.org/10.1186/1471-2105-10-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642772PMC
January 2009

Dopamine receptor D4 gene -521C/T polymorphism is associated with opioid dependence through cold-pain responses.

Ann N Y Acad Sci 2008 Oct;1139:20-6

Department of Anatomy, The Chinese University of Hong Kong, Shatin, Hong Kong S.A.R., China.

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http://dx.doi.org/10.1196/annals.1432.054DOI Listing
October 2008

Lack of association between the promoter polymorphism of the MTNR1A gene and adolescent idiopathic scoliosis.

Spine (Phila Pa 1976) 2008 Sep;33(20):2204-7

Spine Surgery, The Affiliated Drum Town Hospital of Nanjing University Medical School, Nanjing, China.

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http://dx.doi.org/10.1097/BRS.0b013e31817e0424DOI Listing
September 2008

Genetic association study of growth hormone receptor and idiopathic scoliosis.

Clin Orthop Relat Res 2007 Sep;462:53-8

Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1097/BLO.0b013e3180986dc2DOI Listing
September 2007

Genetic association of complex traits: using idiopathic scoliosis as an example.

Clin Orthop Relat Res 2007 Sep;462:38-44

Department of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.

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https://insights.ovid.com/crossref?an=00003086-200709000-000
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http://dx.doi.org/10.1097/BLO.0b013e3180d09dccDOI Listing
September 2007

The familial risk and HLA susceptibility among narcolepsy patients in Hong Kong Chinese.

Sleep 2007 Jul;30(7):851-8

Department of Psychiatry, The Chinese University of Hong Kong, Prince of Wales and Shatin Hospitals, Shatin, Hong Kong SAR.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978371PMC
http://dx.doi.org/10.1093/sleep/30.7.851DOI Listing
July 2007

Abnormal expressions of the subunits of the UDP-N-acetylglucosamine: lysosomal enzyme, N-acetylglucosamine-1-phosphotransferase, result in the formation of cytoplasmic vacuoles resembling those of the I-cells.

J Mol Med (Berl) 2007 Apr 8;85(4):351-60. Epub 2006 Dec 8.

Anatomical and Cellular Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR.

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http://dx.doi.org/10.1007/s00109-006-0128-3DOI Listing
April 2007

The alpha(1S) subunit of the L-type calcium channel is not a predisposition gene for thyrotoxic periodic paralysis.

Clin Endocrinol (Oxf) 2007 Feb;66(2):229-34

Department of Chemical Pathology, Faculty of Medicine, The Chinese Univerisity of Hong Kong SAR, China.

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http://dx.doi.org/10.1111/j.1365-2265.2006.02713.xDOI Listing
February 2007

Apolipoprotein E epsilon4 allele is associated with vascular dementia.

Dement Geriatr Cogn Disord 2006 22;22(4):301-5. Epub 2006 Aug 22.

Department of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China.

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http://dx.doi.org/10.1159/000095246DOI Listing
January 2007

Genetic association study between mbl2 and asthma phenotypes in Chinese children.

Pediatr Allergy Immunol 2006 Nov;17(7):501-7

Department of Paediatrics, The Chinese Univesity of Hong Kong, Prince of Wales Hospital, Hong Kong.

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http://dx.doi.org/10.1111/j.1399-3038.2006.00446.xDOI Listing
November 2006

Apolipoprotein epsilon-4 allele and the two-year progression of cognitive function in Chinese subjects with late-onset Alzheimer's disease.

Am J Alzheimers Dis Other Demen 2006 Mar-Apr;21(2):92-9

Department of Psychiatry, the Chinese University of Hong Kong, Shatin, Hong Kong, SAR.

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http://dx.doi.org/10.1177/153331750602100208DOI Listing
September 2006

Hepatitis C virus genotype distribution among intravenous drug user and the general population in Hong Kong.

J Med Virol 2006 May;78(5):574-81

Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/jmv.20578DOI Listing
May 2006

Evaluation of an algorithm of tagging SNPs selection by linkage disequilibrium.

Clin Biochem 2006 Mar 19;39(3):240-3. Epub 2006 Jan 19.

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1016/j.clinbiochem.2005.11.014DOI Listing
March 2006

How the SARS coronavirus causes disease: host or organism?

J Pathol 2006 Jan;208(2):142-51

Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, China.

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http://dx.doi.org/10.1002/path.1897DOI Listing
January 2006

Gene-gene interactions for asthma and plasma total IgE concentration in Chinese children.

J Allergy Clin Immunol 2006 Jan 2;117(1):127-33. Epub 2005 Dec 2.

Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

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http://dx.doi.org/10.1016/j.jaci.2005.09.031DOI Listing
January 2006

Novel mutations in type 2 Gaucher disease in Chinese and their functional characterization by heterologous expression.

Hum Mutat 2005 Jul;26(1):59-60

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China.

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http://dx.doi.org/10.1002/humu.9348DOI Listing
July 2005

Type I Gaucher disease with exophthalmos and pulmonary arteriovenous malformation.

BMC Med Genet 2005 Jun 9;6:25. Epub 2005 Jun 9.

Departments of Pediatric, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1186/1471-2350-6-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1164415PMC
June 2005

CD14 and toll-like receptors: potential contribution of genetic factors and mechanisms to inflammation and allergy.

Curr Drug Targets Inflamm Allergy 2005 Apr;4(2):169-75

Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.

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April 2005

Isolate diffuse thickening of glomerular capillary basement membrane: a renal lesion in prediabetes?

Mod Pathol 2004 Dec;17(12):1506-12

Department of Anatomical & Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China.

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http://dx.doi.org/10.1038/modpathol.3800219DOI Listing
December 2004

No mutation in the KCNE3 potassium channel gene in Chinese thyrotoxic hypokalaemic periodic paralysis patients.

Clin Endocrinol (Oxf) 2004 Jul;61(1):109-12

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Kong Kong.

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http://doi.wiley.com/10.1111/j.1365-2265.2004.02079.x
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http://dx.doi.org/10.1111/j.1365-2265.2004.02079.xDOI Listing
July 2004

Association between tumor necrosis factor-alpha promoter polymorphism and Alzheimer's disease.

Neurology 2004 Jan;62(2):307-9

Department of Chemical Pathology, Faculty of Medicine, Chinese University of Hong Kong, Shatin, China.

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http://dx.doi.org/10.1212/01.wnl.0000103288.49441.e4DOI Listing
January 2004

The C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese children.

Pediatr Allergy Immunol 2003 Aug;14(4):255-60

Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.

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August 2003

A novel mutation (G233D) in the glycogen phosphorylase gene in a patient with hepatic glycogen storage disease and residual enzyme activity.

Mol Genet Metab 2003 Jun;79(2):142-5

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, China.

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June 2003

Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients.

Int J Cancer 2003 May;104(5):611-6

Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR.

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http://dx.doi.org/10.1002/ijc.10971DOI Listing
May 2003

Carnitine level in Chinese epileptic patients taking sodium valproate.

Pediatr Neurol 2003 Jan;28(1):24-7

Department of Paediatrics; Prince of Wales Hospital, Shatin, Hong Kong.

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http://dx.doi.org/10.1016/s0887-8994(02)00460-5DOI Listing
January 2003

Impact of experimental acute hyponatremia on severe traumatic brain injury in rats: influences on injuries, permeability of blood-brain barrier, ultrastructural features, and aquaporin-4 expression.

Exp Neurol 2002 Dec;178(2):194-206

Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong.

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http://dx.doi.org/10.1006/exnr.2002.8037DOI Listing
December 2002

Genotype spectrum of cervical human papillomavirus infection among sexually transmitted disease clinic patients in Hong Kong.

J Med Virol 2002 Oct;68(2):273-7

Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/jmv.10189DOI Listing
October 2002

A founder mutation (R254X) of SLC22A5 (OCTN2) in Chinese primary carnitine deficiency patients.

Hum Mutat 2002 Sep;20(3):232

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1002/humu.9053DOI Listing
September 2002

Sensitization to common food allergens is a risk factor for asthma in young Chinese children in Hong Kong.

J Asthma 2002 Sep;39(6):523-9

Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR.

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http://dx.doi.org/10.1081/jas-120004922DOI Listing
September 2002

Inhalant allergens as risk factors for the development and severity of mild-to-moderate asthma in Hong Kong Chinese children.

J Asthma 2002 Jun;39(4):323-30

Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR.

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http://dx.doi.org/10.1081/jas-120002289DOI Listing
June 2002

Mutational and haplotype analysis of AGL in patients with glycogen storage disease type III.

J Hum Genet 2002 ;47(2):55-9

Department of Endocrinology and Metabolism, Okinaka Memorial Institute for Medical Research and Toranomon Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s100380200000DOI Listing
May 2002

Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients.

Clin Cancer Res 2002 Feb;8(2):464-70

Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People's Republic of China.

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February 2002

Thromboxane A2 receptor gene polymorphism is associated with the serum concentration of cat-specific immunoglobulin E as well as the development and severity of asthma in Chinese children.

Pediatr Allergy Immunol 2002 Feb;13(1):10-7

Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, SAR, China.

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February 2002

Determinants of cervical human papillomavirus infection: differences between high- and low-oncogenic risk types.

J Infect Dis 2002 Jan 5;185(1):28-35. Epub 2001 Dec 5.

Department of Microbiology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.

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http://dx.doi.org/10.1086/338010DOI Listing
January 2002