Neil E Fleshner

Neil E Fleshner

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Neil E Fleshner

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Risk of Bone Fractures Following Urinary Intestinal Diversion: A Population Based Study.

J Urol 2019 08 8;202(2):319-325. Epub 2019 Jul 8.

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and University of Toronto , Toronto , Ontario , Canada.

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http://dx.doi.org/10.1097/JU.0000000000000213DOI Listing
August 2019

Reply by Authors.

J Urol 2019 08 8;202(2):325. Epub 2019 Jul 8.

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and University of Toronto , Toronto , Ontario , Canada.

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http://dx.doi.org/10.1097/01.JU.0000558494.56102.dbDOI Listing
August 2019

An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer.

Mol Metab 2019 Jul 10;25:119-130. Epub 2019 Apr 10.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600047PMC
July 2019

A Phase 1 Pilot Study of Preoperative Radiation Therapy for Prostate Cancer: Long-Term Toxicity and Oncologic Outcomes.

Int J Radiat Oncol Biol Phys 2019 May 6;104(1):61-66. Epub 2019 Jan 6.

Department of Radiation Oncology, University of Toronto, Toronto, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada; Techna Institute, University Health Network, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.12.054DOI Listing
May 2019

Population-based outcomes of men with a single negative prostate biopsy: Importance of continued follow-up among older patients.

Urol Oncol 2019 May 13;37(5):298.e19-298.e27. Epub 2019 Feb 13.

Department of Surgical Oncology, University Health Network, Toronto, ON, Canada; Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2019.01.030DOI Listing
May 2019

The who, when, and why of primary adrenal malignancies: Insights into the epidemiology of a rare clinical entity.

Cancer 2019 Apr 18;125(7):1050-1059. Epub 2018 Dec 18.

Department of Surgical Oncology, Division of Urology, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/cncr.31916
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http://dx.doi.org/10.1002/cncr.31916DOI Listing
April 2019

Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression.

Clin Epigenetics 2019 03 27;11(1):54. Epub 2019 Mar 27.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 60 Murray Street, L6-304B, Toronto, ON, M5T 3L9, Canada.

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http://dx.doi.org/10.1186/s13148-019-0651-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438015PMC
March 2019

Abiraterone Acetate for Nonmetastatic Castration-Resistant Prostate Cancer-The Forgotten Dance Partner?

JAMA Oncol 2019 Feb;5(2):144-145

Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamaoncol.2018.5191DOI Listing
February 2019

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2019 02;51(2):363

Institute of Cancer Research, London, UK.

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http://www.nature.com/articles/s41588-018-0330-6
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http://dx.doi.org/10.1038/s41588-018-0330-6DOI Listing
February 2019

Statin use and time to progression in men on active surveillance for prostate cancer.

Prostate Cancer Prostatic Dis 2018 11 6;21(4):509-515. Epub 2018 Jun 6.

Division of Urology, Department of Surgery, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41391-018-0053-xDOI Listing
November 2018

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2018 07 11;50(7):928-936. Epub 2018 Jun 11.

Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1038/s41588-018-0142-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568012PMC
July 2018

Assessment of Serum microRNA Biomarkers to Predict Reclassification of Prostate Cancer in Patients on Active Surveillance.

J Urol 2018 06 12;199(6):1475-1481. Epub 2017 Dec 12.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00225347177806
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http://dx.doi.org/10.1016/j.juro.2017.12.006DOI Listing
June 2018

Impact of oral hypoglycemic agents on mortality among diabetic patients with non-muscle-invasive bladder cancer: A populationbased analysis.

Can Urol Assoc J 2018 Jun 23;12(6):203-210. Epub 2018 Feb 23.

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, ON; Canada.

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http://dx.doi.org/10.5489/cuaj.4870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994977PMC
June 2018

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

Authors:
Tokhir Dadaev Edward J Saunders Paul J Newcombe Ezequiel Anokian Daniel A Leongamornlert Mark N Brook Clara Cieza-Borrella Martina Mijuskovic Sarah Wakerell Ali Amin Al Olama Fredrick R Schumacher Sonja I Berndt Sara Benlloch Mahbubl Ahmed Chee Goh Xin Sheng Zhuo Zhang Kenneth Muir Koveela Govindasami Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Hakansson Catharine West Alison M Dunning Neil Burnet Lorelei Mucci Edward Giovannucci Gerald Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry Rosenstein Sarah Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Laura Fachal Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weisher Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Chavdar Slavov Vanio Mitev Matthew Parliament Sandeep Singhal Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Andrzej Kierzek Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Peter Kraft Matthew Freedman Fredrik Wiklund Stephen Chanock Brian E Henderson Douglas F Easton Christopher A Haiman Rosalind A Eeles David V Conti Zsofia Kote-Jarai

Nat Commun 2018 06 11;9(1):2256. Epub 2018 Jun 11.

The Institute of Cancer Research, London, SW7 3RP, UK.

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http://dx.doi.org/10.1038/s41467-018-04109-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995836PMC
June 2018

Prehabilitation for radical prostatectomy: A multicentre randomized controlled trial.

Surg Oncol 2018 Jun 7;27(2):289-298. Epub 2018 May 7.

Department of Anesthesia, McGill University Health Centre, Montreal, Quebec, Canada; Department of Surgery, Division of Urology, McGill University, Quebec, Canada; Department of Anesthesia, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.suronc.2018.05.010DOI Listing
June 2018

Re: Urinary DNA Methylation Biomarkers for Noninvasive Prediction of Aggressive Disease in Patients with Prostate Cancer on Active Surveillance: F. Zhao, E. Olkhov-Mitsel, T. van der Kwast, J. Sykes, D. Zdravic, V. Venkateswaran, A. R. Zlotta, A. Loblaw, N. E. Fleshner, L. Klotz, D. Vesprini and B. Bapat J Urol 2017;197:335-341.

J Urol 2018 05 9;199(5):1354-1355. Epub 2018 Feb 9.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2017.10.061DOI Listing
May 2018

Extended Venous Thromboembolism Prophylaxis after Radical Cystectomy: A Call for Adherence to Current Guidelines.

J Urol 2018 04 4;199(4):906-914. Epub 2017 Nov 4.

Department of Surgery, Division of Urology, University Health Network, Princess Margaret Cancer Center, Toronto, Ontario, Canada; Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2017.08.130DOI Listing
April 2018

Does perioperative chemotherapy improve survival in upper tract urothelial carcinoma? A population based analysis.

Oncotarget 2018 Apr 10;9(27):18797-18810. Epub 2018 Apr 10.

Division of Urology, Department of Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.18632/oncotarget.24694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922356PMC
April 2018

High competing risks minimize real-world utility of adjuvant targeted therapy in renal cell carcinoma: a population-based analysis.

Oncotarget 2018 Mar 30;9(24):16731-16743. Epub 2018 Mar 30.

Department of Surgical Oncology, Division of Urology, University Health Network, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.18632/oncotarget.24675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908282PMC
March 2018

Lymphadenectomy in Gleason 7 prostate cancer: Adherence to guidelines and effect on clinical outcomes.

Urol Oncol 2018 01 14;36(1):13.e11-13.e18. Epub 2017 Sep 14.

Department of Surgical Oncology, University Health Network, University of Toronto, Toronto, Ontario, Canada; Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2017.08.023DOI Listing
January 2018

Body Mass Index, Diet-Related Factors, and Bladder Cancer Prognosis: A Systematic Review and Meta-Analysis.

Bladder Cancer 2018 Jan 20;4(1):91-112. Epub 2018 Jan 20.

Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.3233/BLC-170147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798521PMC
January 2018

Metastatic renal cell carcinoma: Patterns and predictors of metastases-A contemporary population-based series.

Urol Oncol 2017 11 17;35(11):661.e7-661.e14. Epub 2017 Jul 17.

Department of Surgical Oncology, Division of Urologic Oncology, University Health Network and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2017.06.060DOI Listing
November 2017

Creation and internal validation of a biopsy avoidance prediction tool to aid in the choice of diagnostic approach in patients with prostate cancer suspicion.

Urol Oncol 2017 10 7;35(10):604.e17-604.e24. Epub 2017 Aug 7.

Department of Surgery, University Health Network, University of Toronto, Toronto, Canada; Department of Pathology, University Health Network, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2017.06.044DOI Listing
October 2017

Variant Histology and Clinicopathological Features of Prostate Cancer in Men Younger than 50 Years Treated with Radical Prostatectomy.

J Urol 2017 07 24;198(1):79-85. Epub 2017 Jan 24.

Department of Pathology, Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada; Division of Urology, Department of Surgery (MEN, NEF), University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2017.01.061DOI Listing
July 2017

Propensity Score Analysis of Radical Cystectomy Versus Bladder-Sparing Trimodal Therapy in the Setting of a Multidisciplinary Bladder Cancer Clinic.

J Clin Oncol 2017 Jul 14;35(20):2299-2305. Epub 2017 Apr 14.

Girish S. Kulkarni, Thomas Hermanns, Yanliang Wei, Bimal Bhindi, Raj Satkunasivam, Paul Athanasopoulos, Peter J. Bostrom, Kathy Li, Arnoud J. Templeton, Srikala S. Sridhar, Peter Chung, Robert G. Bristow, Michael Milosevic, Padraig Warde, Neil E. Fleshner, Michael A.S. Jewett, Shaheena Bashir, and Alexandre R. Zlotta, Princess Margaret Cancer Center, University Health Network, University of Toronto; Cynthia Kuk and Alexandre R. Zlotta, Mount Sinai Hospital, University of Toronto; Theodorus H. Van Der Kwast, University Health Network, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1200/JCO.2016.69.2327DOI Listing
July 2017

Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder Cancer.

Transl Oncol 2017 Apr 3;10(2):168-177. Epub 2017 Feb 3.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 60 Murray St., Toronto, Ontario, Canada, M5T 3L9; Department of Laboratory Medicine and Pathobiology, University of Toronto, 27 King's College Circle, Toronto, Ontario, Canada, M5S 1A1; Department of Pathology, University Health Network, 200 Elizabeth St., Toronto, Ontario, Canada, M5G 2C4. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19365233163025
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http://dx.doi.org/10.1016/j.tranon.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293735PMC
April 2017

Urinary DNA Methylation Biomarkers for Noninvasive Prediction of Aggressive Disease in Patients with Prostate Cancer on Active Surveillance.

J Urol 2017 02 18;197(2):335-341. Epub 2016 Aug 18.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Pathology, University Health Network, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.08.081DOI Listing
February 2017

Limitations in Predicting Organ Confined Prostate Cancer in Patients with Gleason Pattern 4 on Biopsy: Implications for Active Surveillance.

J Urol 2017 01 22;197(1):75-83. Epub 2016 Jul 22.

Division of Urology, Department of Surgical Oncology, University Health Network, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2016.07.076DOI Listing
January 2017

Effects of long-term androgen deprivation therapy on cognitive function over 36 months in men with prostate cancer.

Cancer 2017 01 1;123(2):237-244. Epub 2016 Sep 1.

Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.30320DOI Listing
January 2017

The Relationship Between Metformin and Serum Prostate-Specific Antigen Levels.

Prostate 2016 11 12;76(15):1445-53. Epub 2016 Jul 12.

Clinical Nutrition and Risk Factor Modification Center, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pros.23228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053259PMC
November 2016

The uptake of active surveillance for the management of prostate cancer: A population-based analysis.

Can Urol Assoc J 2016 Sep-Oct;10(9-10):333-338

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto.

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http://dx.doi.org/10.5489/cuaj.3684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085913PMC
November 2016

The uptake of active surveillance for the management of prostate cancer: A population-based analysis.

Can Urol Assoc J 2016 Sep-Oct;10(9-10):E342-E346. Epub 2016 Oct 13.

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto.

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http://dx.doi.org/10.5489/cuaj.4207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085922PMC
October 2016

Author Reply.

Urology 2016 07 22;93:85. Epub 2016 Apr 22.

Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.urology.2016.01.045DOI Listing
July 2016

Diabetes Mellitus Type 2: A Driving Force for Urological Complications.

Trends Endocrinol Metab 2016 05 8;27(5):249-261. Epub 2016 Mar 8.

Princess Margaret Cancer Centre, University Health Network, 610 University Avenue, M5G 2M9, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2016.02.006DOI Listing
May 2016

Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis.

Clin Epigenetics 2016 15;8:32. Epub 2016 Mar 15.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON Canada ; Mount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto, ON Canada.

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http://dx.doi.org/10.1186/s13148-016-0195-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791926PMC
April 2016

Cancer-related fatigue and associated disability in post-treatment cancer survivors.

J Cancer Surviv 2016 Feb 16;10(1):51-61. Epub 2015 Apr 16.

Cancer Survivorship Program, Princess Margaret Cancer Centre, University Health Network, 200 Elizabeth Street, Munk Building B PMB 148, Toronto, ON, M5G 2C4, Canada.

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http://link.springer.com/content/pdf/10.1007%2Fs11764-015-04
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http://link.springer.com/10.1007/s11764-015-0450-2
Publisher Site
http://dx.doi.org/10.1007/s11764-015-0450-2DOI Listing
February 2016

Identification of the best complete blood count-based predictors for bladder cancer outcomes in patients undergoing radical cystectomy.

Br J Cancer 2016 Jan 10;114(2):207-12. Epub 2015 Dec 10.

Division of Urology, Department of Surgery, University Health Network, University of Toronto, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada.

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http://dx.doi.org/10.1038/bjc.2015.432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815810PMC
January 2016

Phase II, randomised, double-blind, placebo-controlled trial of methylphenidate for reduction of fatigue levels in patients with prostate cancer receiving LHRH-agonist therapy.

BJU Int 2015 Nov 8;116(5):744-52. Epub 2015 Jun 8.

Princess Margaret Cancer Centre, Departments of Surgical Oncology/Urology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/bju.12755DOI Listing
November 2015

Baseline Perineural Invasion is Associated with Shorter Time to Progression in Men with Prostate Cancer Undergoing Active Surveillance: Results from the REDEEM Study.

J Urol 2015 Nov 16;194(5):1258-63. Epub 2015 May 16.

Division of Urology, Department of Surgery and the Samuel Oschin Comprehensive Cancer Institute, Cedars Sinai Medical Center, Los Angeles, California; Urology Section, Veterans Affairs Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.juro.2015.04.113DOI Listing
November 2015

miRNAs dysregulated in association with Gleason grade regulate extracellular matrix, cytoskeleton and androgen receptor pathways.

J Pathol 2015 Oct 24;237(2):226-37. Epub 2015 Jul 24.

Department of Laboratory Medicine, and the Keenan Research Centre for Biomedical Science at the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.

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http://dx.doi.org/10.1002/path.4568DOI Listing
October 2015

Capsaicin reduces the metastatic burden in the transgenic adenocarcinoma of the mouse prostate model.

Prostate 2015 Sep 5;75(12):1300-11. Epub 2015 Jun 5.

Department of Surgery (Urology), Sunnybrook Health Sciences Center, Toronto, Ontario.

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http://dx.doi.org/10.1002/pros.23013DOI Listing
September 2015

The effect of metformin on cancer-specific survival outcomes in diabetic patients undergoing radical cystectomy for urothelial carcinoma of the bladder.

Urol Oncol 2015 Sep 19;33(9):386.e7-13. Epub 2015 Jun 19.

Department of Surgery, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Canada; Department of Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2015.05.024DOI Listing
September 2015

Long-term impact of androgen-deprivation therapy on physical function and quality of life.

Cancer 2015 Jul 24;121(14):2350-7. Epub 2015 Mar 24.

Department of Medicine, University Health Network, Toronto, Canada.

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http://dx.doi.org/10.1002/cncr.29355DOI Listing
July 2015

Health-related quality of life in robotic versus open radical prostatectomy.

Can Urol Assoc J 2015 May-Jun;9(5-6):179-87

Department of Surgery (Urology) and Oncology, Princess Margaret Cancer Centre, University Health Network and the Department of Surgery, University of Toronto, Toronto, ON;

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http://dx.doi.org/10.5489/cuaj.2618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479638PMC
July 2015

Magnetic resonance imaging detected prostate evasive anterior tumours: Further insights.

Can Urol Assoc J 2015 May-Jun;9(5-6):E267-72

Division of Urology, Princess Margaret Hospital, University Health Network, Toronto, ON.

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http://dx.doi.org/10.5489/cuaj.2562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439222PMC
June 2015

The effects of serum from prostate cancer patients with elevated body mass index on prostate cancer cells in vitro.

Lipid Insights 2015 19;8:11-9. Epub 2015 Apr 19.

Division of Urology, Department of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://journals.sagepub.com/doi/10.4137/LPI.S23135
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http://dx.doi.org/10.4137/LPI.S23135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404997PMC
May 2015

Capsaicin: a novel radio-sensitizing agent for prostate cancer.

Prostate 2015 Feb 13;75(2):113-25. Epub 2014 Oct 13.

Division of Urology, Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pros.22896DOI Listing
February 2015

Reply: To PMID 25530379.

Urology 2015 Jan;85(1):171

Division of Urology, Department of Surgery, University Health Network, Toronto, Canada.

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http://dx.doi.org/10.1016/j.urology.2014.07.083DOI Listing
January 2015

Reply from Authors re: Andrea Gallina, Alessandro Nini, Francesco Montorsi, Alberto Briganti. Metabolic Syndrome as a Marker for Prostate Cancer: Still a Work in Progress. Eur Urol 2015;67:71-2.

Eur Urol 2015 Jan 13;67(1):72-73. Epub 2014 Apr 13.

Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.eururo.2014.04.001DOI Listing
January 2015

Perceived quality of interprofessional interactions between physicians and nurses in oncology outpatient clinics.

Eur J Oncol Nurs 2014 Dec 15;18(6):619-25. Epub 2014 Jul 15.

Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ejon.2014.06.004DOI Listing
December 2014

Obesity is associated with risk of progression for low-risk prostate cancers managed expectantly.

Eur Urol 2014 Nov 18;66(5):841-8. Epub 2014 Jun 18.

Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.eururo.2014.06.005DOI Listing
November 2014

Health-related quality of life following radical prostatectomy: long-term outcomes.

Qual Life Res 2014 Oct 9;23(8):2309-17. Epub 2014 Mar 9.

Department of Surgical Oncology, Princess Margaret Cancer Centre, Toronto, ON, Canada,

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http://dx.doi.org/10.1007/s11136-014-0664-1DOI Listing
October 2014

The importance of surgeon characteristics on impacting oncologic outcomes for patients undergoing radical cystectomy.

J Urol 2014 Sep 1;192(3):714-9. Epub 2014 Mar 1.

Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada; Institute for Clinical and Evaluative Sciences, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2014.02.093DOI Listing
September 2014

FGFR3 mutations, but not FGFR3 expression and FGFR3 copy-number variations, are associated with favourable non-muscle invasive bladder cancer.

Virchows Arch 2014 Aug 1;465(2):207-13. Epub 2014 Jun 1.

Department of Surgical Oncology (Urology), The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00428-014-1596-4DOI Listing
August 2014

What we've learned so far about ADT.

Authors:
Neil E Fleshner

Can Urol Assoc J 2014 Jul;8(7-8 Suppl 4):S133

Division of Urology, University Health Network, University of Toronto, Toronto, ON.

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http://dx.doi.org/10.5489/cuaj.2283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145691PMC
July 2014

Metabolic syndrome and diabetes for the urologist.

Can Urol Assoc J 2014 Jul;8(7-8 Suppl 5):S159-61

Resident in Urology, University of Toronto, Toronto, ON.

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http://dx.doi.org/10.5489/cuaj.2314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145702PMC
July 2014

Lean methodology improves efficiency in outpatient academic uro-oncology clinics.

Urology 2014 May 25;83(5):992-7. Epub 2014 Mar 25.

Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.urology.2013.11.048DOI Listing
May 2014

Obesity is associated with larger prostate volume but not with worse urinary symptoms: analysis of a large multiethnic cohort.

Urology 2014 Jan 14;83(1):81-7. Epub 2013 Sep 14.

Division of Urology, Department of Surgical Oncology, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.urology.2013.07.039DOI Listing
January 2014

Impact of provider volume on operative mortality after radical cystectomy in a publicly funded healthcare system.

Can Urol Assoc J 2013 Nov-Dec;7(11-12):425-9

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON; ; Keenan Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto, ON; ; Institute for Clinical Evaluative Sciences, Toronto, ON.

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http://dx.doi.org/10.5489/cuaj.361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876442PMC
January 2014

MicroRNA signature helps distinguish early from late biochemical failure in prostate cancer.

Clin Chem 2013 Nov 19;59(11):1595-603. Epub 2013 Aug 19.

Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute St. Michael's Hospital, Toronto, Canada;

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http://dx.doi.org/10.1373/clinchem.2013.205450DOI Listing
November 2013

Higher surgeon and hospital volume improves long-term survival after radical cystectomy.

Cancer 2013 Oct 9;119(19):3546-54. Epub 2013 Jul 9.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.28235DOI Listing
October 2013

Exercise does not counteract the effects of a "westernized" diet on prostate cancer xenografts.

Prostate 2013 Aug 30;73(11):1223-32. Epub 2013 Apr 30.

Division of Urology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pros.22673DOI Listing
August 2013

Pathological, oncologic and functional outcomes of radical prostatectomy following active surveillance.

J Urol 2013 Jul 12;190(1):91-5. Epub 2013 Jan 12.

Division of Urology, Department of Surgical Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2013.01.019DOI Listing
July 2013

Urologists in cyberspace: A review of the quality of health information from American urologists' websites using three validated tools.

Can Urol Assoc J 2013 Mar-Apr;7(3-4):100-7

Division of Uro-oncology, Department of Surgical Oncology, Princess Margaret Hospital, University of Toronto, Toronto, ON.

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http://dx.doi.org/10.5489/cuaj.501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650761PMC
May 2013