Publications by authors named "Neerja Karnani"

55Publications

Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore.

Cell 2019 10;179(3):736-749.e15

Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China; Computational and Systems Biology, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674193107
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http://dx.doi.org/10.1016/j.cell.2019.09.019DOI Listing
October 2019

Myo-inositol alters 13C-labeled fatty acid metabolism in human placental explants.

J Endocrinol 2019 Aug 1. Epub 2019 Aug 1.

S Chan, Department of Obstetrics and Gynaecology, National University Singapore Yong Loo Lin School of Medicine, Singapore, Singapore.

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http://dx.doi.org/10.1530/JOE-19-0267DOI Listing
August 2019

Metabolism of 13C-Labeled Fatty Acids in Term Human Placental Explants by Liquid Chromatography-Mass Spectrometry.

Endocrinology 2019 06;160(6):1394-1408

Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1210/en.2018-01020DOI Listing
June 2019

HOXA9 is a novel myopia risk gene.

BMC Ophthalmol 2019 Jan 23;19(1):28. Epub 2019 Jan 23.

Center for Myopia and Eye Disease, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.1186/s12886-019-1038-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343304PMC
January 2019

Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP).

Sci Transl Med 2018 08;10(453)

Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.

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http://dx.doi.org/10.1126/scitranslmed.aan0941DOI Listing
August 2018

Improving mass-univariate analysis of neuroimaging data by modelling important unknown covariates: Application to Epigenome-Wide Association Studies.

Neuroimage 2018 06 12;173:57-71. Epub 2018 Feb 12.

Department of Biomedical Engineering, National University of Singapore, Singapore; Clinical Imaging Research Centre, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10538119183007
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http://dx.doi.org/10.1016/j.neuroimage.2018.01.073DOI Listing
June 2018

DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up.

Transl Psychiatry 2018 01 10;8(1):15. Epub 2018 Jan 10.

The Ludmer Centre for Neuroinformatics and Mental Health, Douglas Hospital Research Centre and Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, QC, H4H1R3, Canada.

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http://dx.doi.org/10.1038/s41398-017-0063-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802588PMC
January 2018

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity.

EBioMedicine 2017 May 26;19:60-72. Epub 2017 Apr 26.

NIHR Southampton Biomedical Research Centre, University of Southampton, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1016/j.ebiom.2017.03.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440605PMC
May 2017

Gestational Diabetes Alters Functions in Offspring's Umbilical Cord Cells With Implications for Cardiovascular Health.

Endocrinology 2017 07;158(7):2102-2112

Singapore Institute for Clinical Sciences, Institute of Molecular and Cell Biology, Agency for Science Technology and Research (A*STAR), Singapore 117609.

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http://dx.doi.org/10.1210/en.2016-1889DOI Listing
July 2017

An Alternative Strategy for Pan-acetyl-lysine Antibody Generation.

PLoS One 2016 8;11(9):e0162528. Epub 2016 Sep 8.

Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Republic of Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162528PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015836PMC
August 2017

Gene, Environment and Methylation (GEM): a tool suite to efficiently navigate large scale epigenome wide association studies and integrate genotype and interaction between genotype and environment.

BMC Bioinformatics 2016 Aug 2;17:299. Epub 2016 Aug 2.

School of Computer Science and Engineering, Nanyang Technological University (NTU), Singapore, 639798, Singapore.

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http://dx.doi.org/10.1186/s12859-016-1161-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970299PMC
August 2016

The effect of the intra-S-phase checkpoint on origins of replication in human cells.

Genes Dev 2011 Mar;25(6):621-33

Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virigina 22908, USA.

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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.2029711
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http://dx.doi.org/10.1101/gad.2029711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059835PMC
March 2011

Bubble-chip analysis of human origin distributions demonstrates on a genomic scale significant clustering into zones and significant association with transcription.

Genome Res 2011 Mar 20;21(3):377-89. Epub 2010 Dec 20.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.

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http://genome.cshlp.org/cgi/doi/10.1101/gr.111328.110
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http://dx.doi.org/10.1101/gr.111328.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044852PMC
March 2011

CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation.

Mol Cell 2010 Oct;40(1):9-21

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.molcel.2010.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966975PMC
October 2010

Genomic study of replication initiation in human chromosomes reveals the influence of transcription regulation and chromatin structure on origin selection.

Mol Biol Cell 2010 Feb 2;21(3):393-404. Epub 2009 Dec 2.

Departments of *Biochemistry and Molecular Genetics and Computer Science, University of Virginia, Charlottesville, VA 22908, USA.

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http://www.molbiolcell.org/doi/10.1091/mbc.e09-08-0707
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http://dx.doi.org/10.1091/mbc.e09-08-0707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814785PMC
February 2010

Microarray analysis of DNA replication timing.

Methods Mol Biol 2009 ;556:191-203

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1007/978-1-60327-192-9_14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201590PMC
September 2009

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:
Ewan Birney John A Stamatoyannopoulos Anindya Dutta Roderic Guigó Thomas R Gingeras Elliott H Margulies Zhiping Weng Michael Snyder Emmanouil T Dermitzakis Robert E Thurman Michael S Kuehn Christopher M Taylor Shane Neph Christoph M Koch Saurabh Asthana Ankit Malhotra Ivan Adzhubei Jason A Greenbaum Robert M Andrews Paul Flicek Patrick J Boyle Hua Cao Nigel P Carter Gayle K Clelland Sean Davis Nathan Day Pawandeep Dhami Shane C Dillon Michael O Dorschner Heike Fiegler Paul G Giresi Jeff Goldy Michael Hawrylycz Andrew Haydock Richard Humbert Keith D James Brett E Johnson Ericka M Johnson Tristan T Frum Elizabeth R Rosenzweig Neerja Karnani Kirsten Lee Gregory C Lefebvre Patrick A Navas Fidencio Neri Stephen C J Parker Peter J Sabo Richard Sandstrom Anthony Shafer David Vetrie Molly Weaver Sarah Wilcox Man Yu Francis S Collins Job Dekker Jason D Lieb Thomas D Tullius Gregory E Crawford Shamil Sunyaev William S Noble Ian Dunham France Denoeud Alexandre Reymond Philipp Kapranov Joel Rozowsky Deyou Zheng Robert Castelo Adam Frankish Jennifer Harrow Srinka Ghosh Albin Sandelin Ivo L Hofacker Robert Baertsch Damian Keefe Sujit Dike Jill Cheng Heather A Hirsch Edward A Sekinger Julien Lagarde Josep F Abril Atif Shahab Christoph Flamm Claudia Fried Jörg Hackermüller Jana Hertel Manja Lindemeyer Kristin Missal Andrea Tanzer Stefan Washietl Jan Korbel Olof Emanuelsson Jakob S Pedersen Nancy Holroyd Ruth Taylor David Swarbreck Nicholas Matthews Mark C Dickson Daryl J Thomas Matthew T Weirauch James Gilbert Jorg Drenkow Ian Bell XiaoDong Zhao K G Srinivasan Wing-Kin Sung Hong Sain Ooi Kuo Ping Chiu Sylvain Foissac Tyler Alioto Michael Brent Lior Pachter Michael L Tress Alfonso Valencia Siew Woh Choo Chiou Yu Choo Catherine Ucla Caroline Manzano Carine Wyss Evelyn Cheung Taane G Clark James B Brown Madhavan Ganesh Sandeep Patel Hari Tammana Jacqueline Chrast Charlotte N Henrichsen Chikatoshi Kai Jun Kawai Ugrappa Nagalakshmi Jiaqian Wu Zheng Lian Jin Lian Peter Newburger Xueqing Zhang Peter Bickel John S Mattick Piero Carninci Yoshihide Hayashizaki Sherman Weissman Tim Hubbard Richard M Myers Jane Rogers Peter F Stadler Todd M Lowe Chia-Lin Wei Yijun Ruan Kevin Struhl Mark Gerstein Stylianos E Antonarakis Yutao Fu Eric D Green Ulaş Karaöz Adam Siepel James Taylor Laura A Liefer Kris A Wetterstrand Peter J Good Elise A Feingold Mark S Guyer Gregory M Cooper George Asimenos Colin N Dewey Minmei Hou Sergey Nikolaev Juan I Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham Haiyan Huang Nancy R Zhang Ian Holmes James C Mullikin Abel Ureta-Vidal Benedict Paten Michael Seringhaus Deanna Church Kate Rosenbloom W James Kent Eric A Stone Serafim Batzoglou Nick Goldman Ross C Hardison David Haussler Webb Miller Arend Sidow Nathan D Trinklein Zhengdong D Zhang Leah Barrera Rhona Stuart David C King Adam Ameur Stefan Enroth Mark C Bieda Jonghwan Kim Akshay A Bhinge Nan Jiang Jun Liu Fei Yao Vinsensius B Vega Charlie W H Lee Patrick Ng Atif Shahab Annie Yang Zarmik Moqtaderi Zhou Zhu Xiaoqin Xu Sharon Squazzo Matthew J Oberley David Inman Michael A Singer Todd A Richmond Kyle J Munn Alvaro Rada-Iglesias Ola Wallerman Jan Komorowski Joanna C Fowler Phillippe Couttet Alexander W Bruce Oliver M Dovey Peter D Ellis Cordelia F Langford David A Nix Ghia Euskirchen Stephen Hartman Alexander E Urban Peter Kraus Sara Van Calcar Nate Heintzman Tae Hoon Kim Kun Wang Chunxu Qu Gary Hon Rosa Luna Christopher K Glass M Geoff Rosenfeld Shelley Force Aldred Sara J Cooper Anason Halees Jane M Lin Hennady P Shulha Xiaoling Zhang Mousheng Xu Jaafar N S Haidar Yong Yu Yijun Ruan Vishwanath R Iyer Roland D Green Claes Wadelius Peggy J Farnham Bing Ren Rachel A Harte Angie S Hinrichs Heather Trumbower Hiram Clawson Jennifer Hillman-Jackson Ann S Zweig Kayla Smith Archana Thakkapallayil Galt Barber Robert M Kuhn Donna Karolchik Lluis Armengol Christine P Bird Paul I W de Bakker Andrew D Kern Nuria Lopez-Bigas Joel D Martin Barbara E Stranger Abigail Woodroffe Eugene Davydov Antigone Dimas Eduardo Eyras Ingileif B Hallgrímsdóttir Julian Huppert Michael C Zody Gonçalo R Abecasis Xavier Estivill Gerard G Bouffard Xiaobin Guan Nancy F Hansen Jacquelyn R Idol Valerie V B Maduro Baishali Maskeri Jennifer C McDowell Morgan Park Pamela J Thomas Alice C Young Robert W Blakesley Donna M Muzny Erica Sodergren David A Wheeler Kim C Worley Huaiyang Jiang George M Weinstock Richard A Gibbs Tina Graves Robert Fulton Elaine R Mardis Richard K Wilson Michele Clamp James Cuff Sante Gnerre David B Jaffe Jean L Chang Kerstin Lindblad-Toh Eric S Lander Maxim Koriabine Mikhail Nefedov Kazutoyo Osoegawa Yuko Yoshinaga Baoli Zhu Pieter J de Jong
June 2007

Pan-S replication patterns and chromosomal domains defined by genome-tiling arrays of ENCODE genomic areas.

Genome Res 2007 Jun;17(6):865-76

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://www.genome.org/cgi/doi/10.1101/gr.5427007
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http://dx.doi.org/10.1101/gr.5427007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891345PMC
June 2007

Nuclear localization of RFC40 by RIalpha: a link between cellular signaling and proliferation.

Cancer Biol Ther 2005 Apr 29;4(4):438-9. Epub 2005 Apr 29.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.4161/cbt.4.4.1778DOI Listing
April 2005

Temporal profile of replication of human chromosomes.

Proc Natl Acad Sci U S A 2005 May 21;102(18):6419-24. Epub 2005 Apr 21.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1073/pnas.0405088102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088349PMC
May 2005

ABC multidrug transporter Cdr1p of Candida albicans has divergent nucleotide-binding domains which display functional asymmetry.

FEMS Yeast Res 2004 Oct;5(1):63-72

Membrane Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.

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http://dx.doi.org/10.1016/j.femsyr.2004.07.002DOI Listing
October 2004

Genome-wide expression profile of steroid response in Saccharomyces cerevisiae.

Biochem Biophys Res Commun 2004 Apr;317(2):406-13

Institute of Genomics and Integrative Biology, Mall Road, Delhi 110 007, India.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.053DOI Listing
April 2004

Identification of a negative regulatory element which regulates basal transcription of a multidrug resistance gene CDR1 of Candida albicans.

FEMS Yeast Res 2004 Jan;4(4-5):389-99

Membrane Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110-067, India.

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http://dx.doi.org/10.1016/S1567-1356(03)00204-6DOI Listing
January 2004

Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump.

Biochem Biophys Res Commun 2003 Oct;310(3):869-75

Membrane Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.

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http://dx.doi.org/10.1016/j.bbrc.2003.09.094DOI Listing
October 2003