Neelroop Parikshak

Neelroop Parikshak

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Neelroop Parikshak

Neelroop Parikshak

Publications by authors named "Neelroop Parikshak"

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Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.

Nature 2018 08;560(7718):E30

Center for Autism Research and Treatment and Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, 90095, USA.

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http://dx.doi.org/10.1038/s41586-018-0295-8DOI Listing
August 2018

Sex-chromosome dosage effects on gene expression in humans.

Proc Natl Acad Sci U S A 2018 07 26;115(28):7398-7403. Epub 2018 Jun 26.

Neurogenetics Program, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.

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http://dx.doi.org/10.1073/pnas.1802889115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048519PMC
July 2018

Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex.

J Neurodev Disord 2018 06 1;10(1):18. Epub 2018 Jun 1.

Department of Molecular Biology, Cell Biology and Biochemistry, and Carney Institute for Brain Science, Brown University, Providence, RI, 02912, USA.

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http://dx.doi.org/10.1186/s11689-018-9237-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984825PMC
June 2018

Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.

Nature 2016 12 5;540(7633):423-427. Epub 2016 Dec 5.

Center for Autism Research and Treatment and Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/nature20612DOI Listing
December 2016

Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder.

Nat Neurosci 2016 11 29;19(11):1463-1476. Epub 2016 Aug 29.

Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nn.4373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841760PMC
November 2016

Chromosome conformation elucidates regulatory relationships in developing human brain.

Nature 2016 10 19;538(7626):523-527. Epub 2016 Oct 19.

Department of Neurology, Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/nature19847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358922PMC
October 2016

The road to precision psychiatry: translating genetics into disease mechanisms.

Nat Neurosci 2016 10;19(11):1397-1407

Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nn.4409DOI Listing
October 2016

Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders.

Nat Commun 2016 Feb 19;7:10717. Epub 2016 Feb 19.

Center for Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ncomms10717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762891PMC
February 2016

The PsychENCODE project.

Nat Neurosci 2015 Dec;18(12):1707-12

Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675669PMC
December 2015

Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders.

Nat Rev Genet 2015 Aug 7;16(8):441-58. Epub 2015 Jul 7.

1] Program in Neurobehavioral Genetics, Semel Institute, and Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA. [2] Interdepartmental Program in Neuroscience, University of California, Los Angeles, California 90095, USA. [3] Center for Autism Treatment and Research, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA. [4] Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA.

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http://www.nature.com/articles/nrg3934
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http://dx.doi.org/10.1038/nrg3934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699316PMC
August 2015

Specific responses of human hippocampal neurons are associated with better memory.

Proc Natl Acad Sci U S A 2015 Aug 3;112(33):10503-8. Epub 2015 Aug 3.

Department of Neurosurgery, David Geffen School of Medicine and Semel Institute For Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095; Functional Neurosurgery Unit, Tel-Aviv Medical Center and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel

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http://dx.doi.org/10.1073/pnas.1423036112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547223PMC
August 2015

A quantitative framework to evaluate modeling of cortical development by neural stem cells.

Neuron 2014 Jul;83(1):69-86

Neurogenetics Program, Department of Neurology, Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.05.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277209PMC
July 2014

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism.

Cell 2013 Nov;155(5):1008-21

Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Interdepartmental Program in Neuroscience, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.cell.2013.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934107PMC
November 2013

Rare inherited variation in autism: beginning to see the forest and a few trees.

Neuron 2013 Jan;77(2):209-11

Program in Neurogenetics, Department of Neurology and Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S08966273130005
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http://dx.doi.org/10.1016/j.neuron.2013.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691080PMC
January 2013

RBFOX1 regulates both splicing and transcriptional networks in human neuronal development.

Hum Mol Genet 2012 Oct 23;21(19):4171-86. Epub 2012 Jun 23.

Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/hmg/dds240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441119PMC
October 2012

Brain structure and obesity.

Hum Brain Mapp 2010 Mar;31(3):353-64

Department of Pathology, University of Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1002/hbm.20870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826530PMC
March 2010

Measurement of cortical thickness from MRI by minimum line integrals on soft-classified tissue.

Hum Brain Mapp 2009 Oct;30(10):3188-99

Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1002/hbm.20740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903209PMC
October 2009

Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls.

Neuroimage 2009 Mar 8;45(1 Suppl):S3-15. Epub 2008 Nov 8.

Laboratory of Neuro Imaging, Dept. of Neurology, UCLA School of Medicine, Neuroscience Research Building 225E, 635 Charles Young Drive, Los Angeles, CA 90095-1769, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2008.10.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733354PMC
March 2009

Tensor-based morphometry as a neuroimaging biomarker for Alzheimer's disease: an MRI study of 676 AD, MCI, and normal subjects.

Neuroimage 2008 Nov 22;43(3):458-69. Epub 2008 Jul 22.

Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Neuroscience Research Building 225E, 635 Charles Young Drive, Los Angeles, CA 90095-1769, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2008.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197851PMC
November 2008

SEGMENTATION-FREE MEASURING OF CORTICAL THICKNESS FROM MRI.

Proc IEEE Int Symp Biomed Imaging 2008 May;2008:1625-1628

Laboratory of Neuro Imaging, University of California-Los Angeles, School of Medicine, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1109/ISBI.2008.4541324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346190PMC
May 2008