Publications by authors named "Neelamegam Devarasu"

2 Publications

  • Page 1 of 1

Dual-frequency bioelectrical phase angle to estimate the platelet count for the prognosis of dengue fever in Indian children.

Biomed Tech (Berl) 2020 Aug;65(4):417-428

Department of Electronics and Communication Engineering, Pondicherry Engineering College, Puducherry 605014, India.

A noninvasive investigation to ascertain the platelet (PLT) count was conducted on 44 hospitalized dengue hemorrhagic fever (DHF) subjects, male and female aged between 3 and 14 years using bioelectrical phase angle (BPhA). Among the 44 subjects, 30 subjects were confirmed to be non-structural protein-1 (NS1) positive at the time of admission, whose blood investigations such as hematocrit (HCT) level, PLT count, aspartate aminotransferase (AST) level and alanine aminotransferase (ALT) level were performed for the classification of risk as low-risk (LR) and high-risk (HR) DHF. It was found that the BPhA of the body reflects a linear correlation with the PLT count. To provide a better and more accurate estimate of PLT, a dual-frequency method is proposed to calculate the phase angle of the total body. The resistance at 5 kHz and reactance at 100 kHz were used to estimate the phase angle of the total body. The statistical analysis identified that the PLT count estimated using the proposed dual-frequency method shows a good correlation with the blood investigation results. In addition, statistical analysis of the proposed method on other fever subjects indicated a significant difference with DHF.
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http://dx.doi.org/10.1515/bmt-2018-0203DOI Listing
August 2020

Dual frequency bioelectrical impedance analysis to estimate hematocrit for prognosis of dengue fever in Indian children.

Biomed Tech (Berl) 2019 Aug;64(4):459-469

Department of Electronics and Communication Engineering, Pondicherry Engineering College, Puducherry, India.

A noninvasive investigation to ascertain the hematocrit (HCT) or packed cell volume (PCV) was conducted on 44 hospitalized dengue hemorrhagic fever (DHF) subjects, male and female aged between 3 and 14 years using bioelectrical impedance analysis (BIA). Among the 44 subjects, 30 subjects were confirmed to be non-structural protein-1 (NS1) positive at the time of admission, whose blood investigations such as HCT level, platelet (PLT) count, aspartate aminotransferase (AST) level and alanine aminotransferase (ALT) level were taken for the classification of risk as low risk (LR) and high risk (HR) DHF. Electrical conductivity of blood reflects a linear correlation with HCT. To provide a better and more accurate estimate of HCT, a dual frequency method is proposed to calculate the conductivities of plasma and blood cells. The resistance at 100 kHz is used to estimate the conductivity of blood cells and the impedance at 5 kHz to estimate the conductivity of plasma. Statistical analysis reveals that the HCT estimated using the proposed dual frequency method shows a significant difference with a single frequency (50 kHz) estimate of HCT and also shows a good correlation with the blood investigation results. In addition, statistical analysis of the proposed method on different fever subjects indicates a significant difference with DHF.
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http://dx.doi.org/10.1515/bmt-2017-0174DOI Listing
August 2019
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