Neal S Peachey

Neal S Peachey

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Neal S Peachey

Publications by authors named "Neal S Peachey"

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Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

Cell Mol Life Sci 2019 Sep 3;76(17):3407-3432. Epub 2019 Apr 3.

Department of Ophthalmology, Duke University Medical Center, DUEC 3802, 2351 Erwin Road, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1007/s00018-019-03078-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698218PMC
September 2019

Impact of MCT1 Haploinsufficiency on the Mouse Retina.

Adv Exp Med Biol 2018 ;1074:375-380

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-3-319-75402-4_46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708593PMC
May 2019

Use of Direct Current Electroretinography for Analysis of Retinal Pigment Epithelium Function in Mouse Models.

Methods Mol Biol 2018 ;1753:103-113

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/978-1-4939-7720-8_7DOI Listing
January 2019

Modulating GLUT1 expression in retinal pigment epithelium decreases glucose levels in the retina: impact on photoreceptors and Müller glial cells.

Am J Physiol Cell Physiol 2019 Jan 21;316(1):C121-C133. Epub 2018 Nov 21.

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University , Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1152/ajpcell.00410.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383144PMC
January 2019

Deletion of GLUT1 in mouse lens epithelium leads to cataract formation.

Exp Eye Res 2018 07 28;172:45-53. Epub 2018 Mar 28.

Department of Pathology, Anatomy & Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2018.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716165PMC
July 2018

Author Correction: Prevention of Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome.

Sci Rep 2018 Mar 6;8(1):4289. Epub 2018 Mar 6.

Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41598-018-22647-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840346PMC
March 2018

Noninvasive Electroretinographic Procedures for the Study of the Mouse Retina.

Curr Protoc Mouse Biol 2018 Mar;8(1):1-16

Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

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http://dx.doi.org/10.1002/cpmo.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060644PMC
March 2018

A mutagenesis-derived mouse mutant with abnormal retinal vasculature and low bone mineral density.

Mol Vis 2017 18;23:140-148. Epub 2017 Mar 18.

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH; Cole Eye Institute, Cleveland Clinic, Cleveland, OH; Louis Stokes Cleveland VA Medical Center, Cleveland, OH.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360454PMC
February 2018

Prevention of Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome.

Sci Rep 2018 01 19;8(1):1286. Epub 2018 Jan 19.

Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41598-018-19592-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775248PMC
January 2018

Rational Tuning of Visual Cycle Modulator Pharmacodynamics.

J Pharmacol Exp Ther 2017 07 5;362(1):131-145. Epub 2017 May 5.

Department of Pharmacology, School of Medicine (P.D.K., J.Z., K.P.), Department of Chemistry (M.B., G.P.T.), Case Western Reserve University, Cleveland, Ohio; Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio (P.D.K., N.S.P.); Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio (J.K., N.S.P.); and Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio (N.S.P.)

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http://dx.doi.org/10.1124/jpet.117.240721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490204PMC
July 2017

Complement anaphylatoxin receptors C3aR and C5aR are required in the pathogenesis of experimental autoimmune uveitis.

J Leukoc Biol 2016 Mar 22;99(3):447-54. Epub 2015 Sep 22.

*Eye Research Institute, Tianjin Medical University Eye Center, Tianjin, China; Department of Immunology, Lerner Research Institute, Department of Ophthalmic Research, Cole Eye Institute, and Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio, USA; and Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1189/jlb.3A0415-157RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608042PMC
March 2016

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

Authors:
Lars G Fritsche Wilmar Igl Jessica N Cooke Bailey Felix Grassmann Sebanti Sengupta Jennifer L Bragg-Gresham Kathryn P Burdon Scott J Hebbring Cindy Wen Mathias Gorski Ivana K Kim David Cho Donald Zack Eric Souied Hendrik P N Scholl Elisa Bala Kristine E Lee David J Hunter Rebecca J Sardell Paul Mitchell Joanna E Merriam Valentina Cipriani Joshua D Hoffman Tina Schick Yara T E Lechanteur Robyn H Guymer Matthew P Johnson Yingda Jiang Chloe M Stanton Gabriëlle H S Buitendijk Xiaowei Zhan Alan M Kwong Alexis Boleda Matthew Brooks Linn Gieser Rinki Ratnapriya Kari E Branham Johanna R Foerster John R Heckenlively Mohammad I Othman Brendan J Vote Helena Hai Liang Emmanuelle Souzeau Ian L McAllister Timothy Isaacs Janette Hall Stewart Lake David A Mackey Ian J Constable Jamie E Craig Terrie E Kitchner Zhenglin Yang Zhiguang Su Hongrong Luo Daniel Chen Hong Ouyang Ken Flagg Danni Lin Guanping Mao Henry Ferreyra Klaus Stark Claudia N von Strachwitz Armin Wolf Caroline Brandl Guenther Rudolph Matthias Olden Margaux A Morrison Denise J Morgan Matthew Schu Jeeyun Ahn Giuliana Silvestri Evangelia E Tsironi Kyu Hyung Park Lindsay A Farrer Anton Orlin Alexander Brucker Mingyao Li Christine A Curcio Saddek Mohand-Saïd José-Alain Sahel Isabelle Audo Mustapha Benchaboune Angela J Cree Christina A Rennie Srinivas V Goverdhan Michelle Grunin Shira Hagbi-Levi Peter Campochiaro Nicholas Katsanis Frank G Holz Frédéric Blond Hélène Blanché Jean-François Deleuze Robert P Igo Barbara Truitt Neal S Peachey Stacy M Meuer Chelsea E Myers Emily L Moore Ronald Klein Michael A Hauser Eric A Postel Monique D Courtenay Stephen G Schwartz Jaclyn L Kovach William K Scott Gerald Liew Ava G Tan Bamini Gopinath John C Merriam R Theodore Smith Jane C Khan Humma Shahid Anthony T Moore J Allie McGrath Reneé Laux Milam A Brantley Anita Agarwal Lebriz Ersoy Albert Caramoy Thomas Langmann Nicole T M Saksens Eiko K de Jong Carel B Hoyng Melinda S Cain Andrea J Richardson Tammy M Martin John Blangero Daniel E Weeks Bal Dhillon Cornelia M van Duijn Kimberly F Doheny Jane Romm Caroline C W Klaver Caroline Hayward Michael B Gorin Michael L Klein Paul N Baird Anneke I den Hollander Sascha Fauser John R W Yates Rando Allikmets Jie Jin Wang Debra A Schaumberg Barbara E K Klein Stephanie A Hagstrom Itay Chowers Andrew J Lotery Thierry Léveillard Kang Zhang Murray H Brilliant Alex W Hewitt Anand Swaroop Emily Y Chew Margaret A Pericak-Vance Margaret DeAngelis Dwight Stambolian Jonathan L Haines Sudha K Iyengar Bernhard H F Weber Gonçalo R Abecasis Iris M Heid

Nat Genet 2016 Feb 21;48(2):134-43. Epub 2015 Dec 21.

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.3448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745342PMC
February 2016

Light-Regulated Thyroid Hormone Signaling Is Required for Rod Photoreceptor Development in the Mouse Retina.

Invest Ophthalmol Vis Sci 2015 Dec;56(13):8248-57

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States 2Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, United States.

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http://dx.doi.org/10.1167/iovs.15-17743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733501PMC
December 2015

Deficiency of CC chemokine ligand 2 and decay-accelerating factor causes retinal degeneration in mice.

Exp Eye Res 2015 Sep 3;138:126-33. Epub 2015 Jul 3.

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA; Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.exer.2015.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509212PMC
September 2015

Glycosylation of rhodopsin is necessary for its stability and incorporation into photoreceptor outer segment discs.

Hum Mol Genet 2015 May 30;24(10):2709-23. Epub 2015 Jan 30.

Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA,

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http://dx.doi.org/10.1093/hmg/ddv031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406288PMC
May 2015

Ciliary neurotrophic factor for macular telangiectasia type 2: results from a phase 1 safety trial.

Am J Ophthalmol 2015 Apr 19;159(4):659-666.e1. Epub 2014 Dec 19.

Department of Inherited Eye Disease, Moorfields Eye Hospital, London, United Kingdom.

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http://dx.doi.org/10.1016/j.ajo.2014.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361328PMC
April 2015

Early retinal pigment epithelium dysfunction is concomitant with hyperglycemia in mouse models of type 1 and type 2 diabetes.

J Neurophysiol 2015 Feb 26;113(4):1085-99. Epub 2014 Nov 26.

Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio; Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio; and Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1152/jn.00761.2014DOI Listing
February 2015

Transient receptor potential melastatin 1: a hair cell transduction channel candidate.

PLoS One 2013 11;8(10):e77213. Epub 2013 Oct 11.

Otolaryngology Head and Neck Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077213PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795643PMC
August 2014

Presence of the Gpr179(nob5) allele in a C3H-derived transgenic mouse.

Mol Vis 2013 31;19:2615-25. Epub 2013 Dec 31.

Department of Ophthalmology, Inselspital, University of Bern, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883591PMC
July 2014

Inducing a visceral organ to protect a peripheral capillary bed: stabilizing hepatic HIF-1α prevents oxygen-induced retinopathy.

Am J Pathol 2014 Jun 13;184(6):1890-9. Epub 2014 Apr 13.

Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio; Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.02.017DOI Listing
June 2014

Mouse b-wave mutants.

Doc Ophthalmol 2014 Apr 7;128(2):77-89. Epub 2014 Jan 7.

Rehabilitation Research and Development Center of Excellence, Atlanta VA Medical Center, 1670 Clairmont Road, Decatur, GA, 30033, USA.

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http://dx.doi.org/10.1007/s10633-013-9424-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010232PMC
April 2014

GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.

J Neurosci 2014 Apr;34(18):6334-43

Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, Kentucky 40202, Department of Psychological and Brain Sciences, University of Louisville, Louisville, Kentucky 40292, Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, Kentucky 40202, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio 44106, Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44195, and Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky 40202.

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http://dx.doi.org/10.1523/JNEUROSCI.4044-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004817PMC
April 2014

Myosin 6 is required for iris development and normal function of the outer retina.

Invest Ophthalmol Vis Sci 2013 Nov 1;54(12):7223-33. Epub 2013 Nov 1.

Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio.

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http://dx.doi.org/10.1167/iovs.13-12887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816618PMC
November 2013

Ultrastructural localization of GPR179 and the impact of mutant forms on retinal function in CSNB1 patients and a mouse model.

Invest Ophthalmol Vis Sci 2013 Oct 23;54(10):6973-81. Epub 2013 Oct 23.

Retinal Signal Processing, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1167/iovs.13-12293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808102PMC
October 2013

Seven new loci associated with age-related macular degeneration.

Authors:
Lars G Fritsche Wei Chen Matthew Schu Brian L Yaspan Yi Yu Gudmar Thorleifsson Donald J Zack Satoshi Arakawa Valentina Cipriani Stephan Ripke Robert P Igo Gabriëlle H S Buitendijk Xueling Sim Daniel E Weeks Robyn H Guymer Joanna E Merriam Peter J Francis Gregory Hannum Anita Agarwal Ana Maria Armbrecht Isabelle Audo Tin Aung Gaetano R Barile Mustapha Benchaboune Alan C Bird Paul N Bishop Kari E Branham Matthew Brooks Alexander J Brucker William H Cade Melinda S Cain Peter A Campochiaro Chi-Chao Chan Ching-Yu Cheng Emily Y Chew Kimberly A Chin Itay Chowers David G Clayton Radu Cojocaru Yvette P Conley Belinda K Cornes Mark J Daly Baljean Dhillon Albert O Edwards Evangelos Evangelou Jesen Fagerness Henry A Ferreyra James S Friedman Asbjorg Geirsdottir Ronnie J George Christian Gieger Neel Gupta Stephanie A Hagstrom Simon P Harding Christos Haritoglou John R Heckenlively Frank G Holz Guy Hughes John P A Ioannidis Tatsuro Ishibashi Peronne Joseph Gyungah Jun Yoichiro Kamatani Nicholas Katsanis Claudia N Keilhauer Jane C Khan Ivana K Kim Yutaka Kiyohara Barbara E K Klein Ronald Klein Jaclyn L Kovach Igor Kozak Clara J Lee Kristine E Lee Peter Lichtner Andrew J Lotery Thomas Meitinger Paul Mitchell Saddek Mohand-Saïd Anthony T Moore Denise J Morgan Margaux A Morrison Chelsea E Myers Adam C Naj Yusuke Nakamura Yukinori Okada Anton Orlin M Carolina Ortube Mohammad I Othman Chris Pappas Kyu Hyung Park Gayle J T Pauer Neal S Peachey Olivier Poch Rinki Ratna Priya Robyn Reynolds Andrea J Richardson Raymond Ripp Guenther Rudolph Euijung Ryu José-Alain Sahel Debra A Schaumberg Hendrik P N Scholl Stephen G Schwartz William K Scott Humma Shahid Haraldur Sigurdsson Giuliana Silvestri Theru A Sivakumaran R Theodore Smith Lucia Sobrin Eric H Souied Dwight E Stambolian Hreinn Stefansson Gwen M Sturgill-Short Atsushi Takahashi Nirubol Tosakulwong Barbara J Truitt Evangelia E Tsironi André G Uitterlinden Cornelia M van Duijn Lingam Vijaya Johannes R Vingerling Eranga N Vithana Andrew R Webster H-Erich Wichmann Thomas W Winkler Tien Y Wong Alan F Wright Diana Zelenika Ming Zhang Ling Zhao Kang Zhang Michael L Klein Gregory S Hageman G Mark Lathrop Kari Stefansson Rando Allikmets Paul N Baird Michael B Gorin Jie Jin Wang Caroline C W Klaver Johanna M Seddon Margaret A Pericak-Vance Sudha K Iyengar John R W Yates Anand Swaroop Bernhard H F Weber Michiaki Kubo Margaret M Deangelis Thierry Léveillard Unnur Thorsteinsdottir Jonathan L Haines Lindsay A Farrer Iris M Heid Gonçalo R Abecasis

Nat Genet 2013 Apr 3;45(4):433-9, 439e1-2. Epub 2013 Mar 3.

Institute of Human Genetics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.2578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739472PMC
April 2013

Response properties of slow PIII in the Large (vls) mutant.

Doc Ophthalmol 2012 Dec 4;125(3):203-9. Epub 2012 Aug 4.

Louis Stokes Cleveland VA Medical Center, 10701 East Boulevard, Cleveland, OH, 44106, USA.

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http://dx.doi.org/10.1007/s10633-012-9347-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706866PMC
December 2012

A novel role of complement in retinal degeneration.

Invest Ophthalmol Vis Sci 2012 Nov 19;53(12):7684-92. Epub 2012 Nov 19.

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1167/iovs.12-10069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606790PMC
November 2012

Exclusion of aldose reductase as a mediator of ERG deficits in a mouse model of diabetic eye disease.

Vis Neurosci 2012 Nov 29;29(6):267-74. Epub 2012 Oct 29.

Research Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio 44106, USA.

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http://www.journals.cambridge.org/abstract_S0952523812000326
Publisher Site
http://dx.doi.org/10.1017/S0952523812000326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745719PMC
November 2012

Abnormal vascularization in mouse retina with dysregulated retinal cholesterol homeostasis.

J Clin Invest 2012 Aug 23;122(8):3012-23. Epub 2012 Jul 23.

Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1172/JCI63816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408752PMC
August 2012

Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.

J Neurosci 2012 May;32(20):6859-68

The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0267-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383066PMC
May 2012

Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia.

Exp Eye Res 2012 Mar 16;96(1):124-31. Epub 2011 Dec 16.

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.exer.2011.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368555PMC
March 2012

Visual abnormalities associated with enhanced optic nerve myelination.

Brain Res 2011 Feb 21;1374:36-42. Epub 2010 Dec 21.

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.brainres.2010.12.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395475PMC
February 2011

Mutation screen of beta-crystallin genes in 274 patients with age-related macular degeneration.

Ophthalmic Genet 2010 Sep;31(3):129-34

Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.

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http://dx.doi.org/10.3109/13816810.2010.486774DOI Listing
September 2010

Light-evoked responses of the retinal pigment epithelium: changes accompanying photoreceptor loss in the mouse.

J Neurophysiol 2010 Jul 19;104(1):391-402. Epub 2010 May 19.

Research Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1152/jn.00088.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904221PMC
July 2010

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

Proc Natl Acad Sci U S A 2010 Apr 12;107(16):7401-6. Epub 2010 Apr 12.

Center for Statistical Genetics, Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.0912702107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867722PMC
April 2010

Protective effect of paraoxonase 1 gene variant Gln192Arg in age-related macular degeneration.

Am J Ophthalmol 2010 Mar 30;149(3):513-22. Epub 2009 Dec 30.

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1016/j.ajo.2009.09.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026437PMC
March 2010

Suppression of Ca2+ signaling in a mouse model of Best disease.

Hum Mol Genet 2010 Mar 6;19(6):1108-18. Epub 2010 Jan 6.

Department of Ophthalmology and Vision Science, University of Arizona, 655 N. Alvernon Way, Suite 108, Tucson, AZ 85711, USA.

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http://dx.doi.org/10.1093/hmg/ddp583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830833PMC
March 2010

Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization.

Cell 2009 Oct;139(2):285-98

Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.cell.2009.07.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779707PMC
October 2009

Early synaptic defects in tulp1-/- mice.

Invest Ophthalmol Vis Sci 2009 Jul 14;50(7):3074-83. Epub 2009 Feb 14.

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1167/iovs.08-3190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021947PMC
July 2009

Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers.

Mol Cell Proteomics 2009 Jun 6;8(6):1338-49. Epub 2009 Feb 6.

Cole Eye Institute, Lerner Research Inst., Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1074/mcp.M800453-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690477PMC
June 2009

Functional roles of bestrophins in ocular epithelia.

Prog Retin Eye Res 2009 May 4;28(3):206-26. Epub 2009 May 4.

Department of Ophthalmology and Vision Science, University of Arizona, Tucson, AZ 85711, USA.

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http://dx.doi.org/10.1016/j.preteyeres.2009.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740978PMC
May 2009

A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells.

J Neurosci 2009 May;29(19):6088-93

Department of Ophthalmology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0132-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752970PMC
May 2009

Ankyrin-B is required for coordinated expression of beta-2-spectrin, the Na/K-ATPase and the Na/Ca exchanger in the inner segment of rod photoreceptors.

Exp Eye Res 2009 Jan 1;88(1):57-64. Epub 2008 Nov 1.

Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.exer.2008.09.022DOI Listing
January 2009

Attenuation of oscillatory potentials in nob2 mice.

Doc Ophthalmol 2007 Nov 4;115(3):173-86. Epub 2007 May 4.

Cole Eye Institute (I-31), Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1007/s10633-007-9058-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883774PMC
November 2007

Electrophysiologic assessment of the mouse visual system.

Doc Ophthalmol 2007 Nov 7;115(3):125. Epub 2007 Sep 7.

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http://dx.doi.org/10.1007/s10633-007-9080-yDOI Listing
November 2007

Status of the feline retina 5 years after subretinal implantation.

J Rehabil Res Dev 2006 Sep-Oct;43(6):723-32

Atlanta Department of Veterans Affairs Medical Center, Decatur, GA 30033, USA.

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October 2007

Formation and progression of sub-retinal pigment epithelium deposits in Efemp1 mutation knock-in mice: a model for the early pathogenic course of macular degeneration.

Hum Mol Genet 2007 Oct 30;16(20):2423-32. Epub 2007 Jul 30.

Department of Ophthalmology and Vision Science, University of Arizona, Tucson, AZ 85711, USA.

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http://dx.doi.org/10.1093/hmg/ddm199DOI Listing
October 2007

An intramembrane glutamic acid governs peripherin/rds function for photoreceptor disk morphogenesis.

Invest Ophthalmol Vis Sci 2007 Jul;48(7):2975-86

Eye Research Institute, Oakland University, Rochester, Michigan 48309, USA.

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http://dx.doi.org/10.1167/iovs.07-0049DOI Listing
July 2007

Interaction between the photoreceptor-specific tubby-like protein 1 and the neuronal-specific GTPase dynamin-1.

Invest Ophthalmol Vis Sci 2007 Jun;48(6):2837-44

Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1167/iovs.06-0059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021943PMC
June 2007

Branch retinal artery occlusion associated with compound heterozygous genotype for methylenetetrahydrofolate reductase.

Doc Ophthalmol 2007 May 15;114(3):163-8. Epub 2007 Mar 15.

Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://link.springer.com/content/pdf/10.1007/s10633-007-9051
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http://link.springer.com/10.1007/s10633-007-9051-3
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http://dx.doi.org/10.1007/s10633-007-9051-3DOI Listing
May 2007

Voltage-dependent calcium channel CaV1.3 subunits regulate the light peak of the electroretinogram.

J Neurophysiol 2007 May 21;97(5):3731-5. Epub 2007 Mar 21.

Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1152/jn.00146.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846711PMC
May 2007

Partial rescue of retinal function and sterol steady-state in a rat model of Smith-Lemli-Opitz syndrome.

Pediatr Res 2007 Mar;61(3):273-8

Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, Missouri 63104, USA.

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http://dx.doi.org/10.1203/pdr.0b013e318030d1cfDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072818PMC
March 2007

Bilateral macular lesions in a 10-year-old girl.

Am J Ophthalmol 2007 Jan 1;143(1):184-5. Epub 2006 Sep 1.

Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.ajo.2006.07.035DOI Listing
January 2007

Functional abnormalities in the retinal pigment epithelium of CFTR mutant mice.

Exp Eye Res 2006 Aug 14;83(2):424-8. Epub 2006 Apr 14.

Cole Eye Institute, Cole Eye Institute (I-31), Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.exer.2006.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871190PMC
August 2006

Visual cortical plasticity following unilateral sensorimotor cortical lesions in the neonatal rat.

Exp Neurol 2006 May 11;199(1):122-9. Epub 2006 May 11.

Department of Clinical Neurophysiology, The Cyprus Institute of Neurology and Genetics, 6 International Airport Avenue, PO Box 23462, Nicosia, Cyprus.

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http://dx.doi.org/10.1016/j.expneurol.2006.02.115DOI Listing
May 2006

Light-induced exacerbation of retinal degeneration in a rat model of Smith-Lemli-Opitz syndrome.

Exp Eye Res 2006 Mar 19;82(3):496-504. Epub 2005 Dec 19.

Department of Biology, University of Wisconsin Oshkosh, Oshkosh, WI, USA.

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http://dx.doi.org/10.1016/j.exer.2005.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844790PMC
March 2006

Cochlin and glaucoma: a mini-review.

Vis Neurosci 2005 Sep-Oct;22(5):605-13

Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1017/S0952523805225099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483214PMC
January 2006

Pharmacological studies of the mouse cone electroretinogram.

Vis Neurosci 2005 Sep-Oct;22(5):631-6

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1017/S0952523805225129DOI Listing
January 2006

Probing inner retinal circuits in the rod pathway: a comparison of c-fos activation in mutant mice.

Vis Neurosci 2004 Nov-Dec;21(6):873-81

Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1017/S0952523804216078DOI Listing
April 2005

Proteomics reveal Cochlin deposits associated with glaucomatous trabecular meshwork.

J Biol Chem 2005 Feb 3;280(7):6080-4. Epub 2004 Dec 3.

Cole Eye Institute and Lerner Research Institute (i31), Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1074/jbc.M411233200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483217PMC
February 2005

A model of best vitelliform macular dystrophy in rats.

Invest Ophthalmol Vis Sci 2004 Oct;45(10):3733-9

Department of Ophthalmology, University of Arizona College of Medicine, Tucson, Arizona 85711, USA.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
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http://dx.doi.org/10.1167/iovs.04-0307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834278PMC
October 2004

Contribution of Kir4.1 to the mouse electroretinogram.

Mol Vis 2004 Sep 1;10:650-4. Epub 2004 Sep 1.

Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883771PMC
September 2004